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Volumn 373, Issue 4, 1996, Pages 619-631

Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: Neurochemical correlates of selective vulnerability

Author keywords

amyotrophic lateral sclerosis; calbindin; motoneuron; neurofilament; stereology

Indexed keywords

CALBINDIN; CALRETININ; CHOLINE ACETYLTRANSFERASE; NEUROFILAMENT PROTEIN; SUPEROXIDE DISMUTASE;

EID: 0029793872     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960930)373:4<619::AID-CNE9>3.0.CO;2-4     Document Type: Article
Times cited : (83)

References (83)
  • 1
    • 0027946813 scopus 로고
    • The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis
    • Alexianu, M.E., B.-K. Ho, A.H. Mohamed, V. La Bella, R.G. Smith, and S.H. Appel (1994) The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. Ann. Neurol. 36:846-858.
    • (1994) Ann. Neurol. , vol.36 , pp. 846-858
    • Alexianu, M.E.1    Ho, B.-K.2    Mohamed, A.H.3    La Bella, V.4    Smith, R.G.5    Appel, S.H.6
  • 2
    • 0027447304 scopus 로고
    • Calcium-binding proteins: Selective markers of nerve cells
    • Andressen, C., I. Blümcke, and M.R. Celio (1993) Calcium-binding proteins: Selective markers of nerve cells. Cell Tissue Res. 271:181-208.
    • (1993) Cell Tissue Res. , vol.271 , pp. 181-208
    • Andressen, C.1    Blümcke, I.2    Celio, M.R.3
  • 3
    • 0025371643 scopus 로고
    • Calcium-binding proteins, parvalbumin- and calbindin-D28k-immunoreactive neurons in the rat spinal cord and dorsal root ganglia: A light and electron microscopic study
    • Antal, M., T.F. Freund, and E. Polgar (1990) Calcium-binding proteins, parvalbumin- and calbindin-D28k-immunoreactive neurons in the rat spinal cord and dorsal root ganglia: A light and electron microscopic study. J. Comp. Neurol. 295:467-484.
    • (1990) J. Comp. Neurol. , vol.295 , pp. 467-484
    • Antal, M.1    Freund, T.F.2    Polgar, E.3
  • 4
  • 5
    • 0026589438 scopus 로고
    • Distribution of calbindin D28k-like immunoreactivity (LI) in the monkey ventral horn: Do Renshaw cells contain calbindin D28k-LI?
    • Arvidsson, U., B. Ulfhake, S. Cullheim, V. Ramirez, O. Shupliakov, and T. Hökfelt (1992) Distribution of calbindin D28k-like immunoreactivity (LI) in the monkey ventral horn: Do Renshaw cells contain calbindin D28k-LI? J. Neurosci. 12:718-728.
    • (1992) J. Neurosci. , vol.12 , pp. 718-728
    • Arvidsson, U.1    Ulfhake, B.2    Cullheim, S.3    Ramirez, V.4    Shupliakov, O.5    Hökfelt, T.6
  • 6
    • 0027280338 scopus 로고
    • Pathological implications of nitric oxide, superoxide and peroxynitrite formation
    • Beckman, J.S., and J.P. Crow (1993) Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans. 21:330-334.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 330-334
    • Beckman, J.S.1    Crow, J.P.2
  • 8
    • 0027440584 scopus 로고
    • The use of the optical dissector to estimate the number of neurons, glial and endothelial cells in the spinal cord of the mouse - With a comparative note on the rat spinal cord
    • Bjugn, R. (1993) The use of the optical dissector to estimate the number of neurons, glial and endothelial cells in the spinal cord of the mouse - With a comparative note on the rat spinal cord. Brain Res. 627:25-33.
    • (1993) Brain Res. , vol.627 , pp. 25-33
    • Bjugn, R.1
  • 9
    • 0027500127 scopus 로고
    • Estimate of the total number of neurons and glial and endothelial cells in the rat spinal cord by means of the optical dissector
    • Bjugn, R., and H.J.G. Gundersen (1993) Estimate of the total number of neurons and glial and endothelial cells in the rat spinal cord by means of the optical dissector. J. Comp. Neurol. 328:406-414.
    • (1993) J. Comp. Neurol. , vol.328 , pp. 406-414
    • Bjugn, R.1    Gundersen, H.J.G.2
  • 10
    • 0027406083 scopus 로고
    • Motor neurons and neurofilaments in sickness and in health
    • Brady, S.T. (1993) Motor neurons and neurofilaments in sickness and in health. Cell 73:1-3.
    • (1993) Cell , vol.73 , pp. 1-3
    • Brady, S.T.1
  • 11
    • 0025267398 scopus 로고
    • The cells of origin of the spinothalamic tract of the rat: A quantitative reexamination
    • Burstein, R., R.J. Dado, and G.J. Giesler, Jr. (1990) The cells of origin of the spinothalamic tract of the rat: A quantitative reexamination. Brain Res. 511:329-337.
    • (1990) Brain Res. , vol.511 , pp. 329-337
    • Burstein, R.1    Dado, R.J.2    Giesler Jr., G.J.3
  • 12
    • 0024550350 scopus 로고
    • Monoclonal antibody to neurofilament protein (SMI-32) labels a subpopulation of pyramidal neurons in the human and monkey neocortex
    • Campbell, M.J., and J.H. Morrison (1989) Monoclonal antibody to neurofilament protein (SMI-32) labels a subpopulation of pyramidal neurons in the human and monkey neocortex. J. Comp. Neurol. 282:191-205.
    • (1989) J. Comp. Neurol. , vol.282 , pp. 191-205
    • Campbell, M.J.1    Morrison, J.H.2
  • 13
    • 0025358573 scopus 로고
    • Calbindin D-28k and parvalbumin in the rat nervous system
    • Celio, M.R. (1990) Calbindin D-28k and parvalbumin in the rat nervous system. Neuroscience 35:375-475.
    • (1990) Neuroscience , vol.35 , pp. 375-475
    • Celio, M.R.1
  • 14
    • 0027730919 scopus 로고
    • Calcium buffering properties of calbindin D-28k and parvalbumin in rat sensory neurones
    • Chard, P.S., D. Bleakman, S. Christakos, C.S. Fullmer, and R.J. Miller (1993) Calcium buffering properties of calbindin D-28k and parvalbumin in rat sensory neurones. J. Physiol. 472:341-357.
    • (1993) J. Physiol. , vol.472 , pp. 341-357
    • Chard, P.S.1    Bleakman, D.2    Christakos, S.3    Fullmer, C.S.4    Miller, R.J.5
  • 15
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Coté, F., J.-F. Collard, and J.-P. Julien (1993) Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis. Cell 73:35-46.
    • (1993) Cell , vol.73 , pp. 35-46
    • Coté, F.1    Collard, J.-F.2    Julien, J.-P.3
  • 16
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J.T., and P. Puttfarcken (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 17
    • 0023942881 scopus 로고
    • Neurofilament phosphorylation in axons and perikarya: Immunofluorescence study of the rat spinal cord and dorsal root ganglia with monoclonal antibodies
    • Dahl, D., B. Labkovsky, and A. Bignami (1988) Neurofilament phosphorylation in axons and perikarya: Immunofluorescence study of the rat spinal cord and dorsal root ganglia with monoclonal antibodies. J. Comp. Neurol. 271:445-450.
    • (1988) J. Comp. Neurol. , vol.271 , pp. 445-450
    • Dahl, D.1    Labkovsky, B.2    Bignami, A.3
  • 18
    • 0027946294 scopus 로고
    • Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Dal Canto, M.C., and M.E. Gurney (1994) Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Pathol. 145:1271-1279.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1271-1279
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 20
    • 0027417571 scopus 로고
    • Calbindin D-28k and parvalbumin immunoreactivity in the frontal cortex in patients with frontal lobe dementia of non-Alzheimer type associated with amyotrophic lateral sclerosis
    • Ferrer, I., T. Tuñon, M.T. Serrano, R. Casas, S. Alcantara, M.J. Zujar, and R.M. Rivera (1993) Calbindin D-28k and parvalbumin immunoreactivity in the frontal cortex in patients with frontal lobe dementia of non-Alzheimer type associated with amyotrophic lateral sclerosis. Neurol. Neurosurg. Psychiatr. 56:257-261.
    • (1993) Neurol. Neurosurg. Psychiatr. , vol.56 , pp. 257-261
    • Ferrer, I.1    Tuñon, T.2    Serrano, M.T.3    Casas, R.4    Alcantara, S.5    Zujar, M.J.6    Rivera, R.M.7
  • 21
    • 0028001606 scopus 로고
    • Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
    • Figlewicz, D.A., A. Krizus, M.G. Martinoli, V. Meininger, M. Dib, G.A. Rouleau, and J.-P. Julien (1994) Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet. 3:1757-1761.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1757-1761
    • Figlewicz, D.A.1    Krizus, A.2    Martinoli, M.G.3    Meininger, V.4    Dib, M.5    Rouleau, G.A.6    Julien, J.-P.7
  • 22
    • 0016138931 scopus 로고
    • Synaptic connections made by horizontal cells within the outer plexiform layer of the retina of the cat and the rabbit
    • Fisher, S.K., and B.B. Boycott (1974) Synaptic connections made by horizontal cells within the outer plexiform layer of the retina of the cat and the rabbit. Proc. R. Soc. London B. 186:317-331.
    • (1974) Proc. R. Soc. London B. , vol.186 , pp. 317-331
    • Fisher, S.K.1    Boycott, B.B.2
  • 24
    • 0022499336 scopus 로고
    • The spinothalamic system of the rat. I. Location of cells of origin
    • Granum, S.L. (1986) The spinothalamic system of the rat. I. Location of cells of origin. J. Comp. Neurol. 247:159-180.
    • (1986) J. Comp. Neurol. , vol.247 , pp. 159-180
    • Granum, S.L.1
  • 27
    • 0024370364 scopus 로고
    • Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities
    • Hendry, S.H., E.G. Jones, P.C. Emson, D.E. Lawson, C.W. Heizmann, and P. Streit (1989) Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities. Exp. Brain Res. 76:467-72.
    • (1989) Exp. Brain Res. , vol.76 , pp. 467-472
    • Hendry, S.H.1    Jones, E.G.2    Emson, P.C.3    Lawson, D.E.4    Heizmann, C.W.5    Streit, P.6
  • 28
    • 0026042995 scopus 로고
    • Cytopathology of amyotrophic lateral sclerosis
    • L.P. Rowland (ed): New York: Raven Press, Ltd.
    • Hirano, A. (1991) Cytopathology of amyotrophic lateral sclerosis. In L.P. Rowland (ed): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York: Raven Press, Ltd., pp. 91-101.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 91-101
    • Hirano, A.1
  • 29
    • 0014063240 scopus 로고
    • Familial amyotrophic lateral sclerosis
    • Hirano, A., L.T. Kurland, and G.P. Sayre (1967) Familial amyotrophic lateral sclerosis. Arch. Neurol. 16:232-243.
    • (1967) Arch. Neurol. , vol.16 , pp. 232-243
    • Hirano, A.1    Kurland, L.T.2    Sayre, G.P.3
  • 30
    • 0028957486 scopus 로고
    • Neurofilament protein defines regional patterns of cortical organization in the macaque monkey visual system: A quantitative immunohistochemical analysis
    • Hof, P.R., and J.H. Morrison (1995) Neurofilament protein defines regional patterns of cortical organization in the macaque monkey visual system: A quantitative immunohistochemical analysis. J. Comp. Neurol. 352:161-186.
    • (1995) J. Comp. Neurol. , vol.352 , pp. 161-186
    • Hof, P.R.1    Morrison, J.H.2
  • 31
    • 0025036899 scopus 로고
    • Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: I. Superior frontal and inferior temporal cortex
    • Hof, P.R., K. Cox, and J.H. Morrison (1990) Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: I. Superior frontal and inferior temporal cortex. J. Comp. Neurol. 301:44-54.
    • (1990) J. Comp. Neurol. , vol.301 , pp. 44-54
    • Hof, P.R.1    Cox, K.2    Morrison, J.H.3
  • 32
    • 0027231535 scopus 로고
    • Calretinin-immunoreactive neocortical interneurons are unaffected in Alzheimer's disease
    • Hof, P.R., E.A. Nimchinsky, M.R. Celio, C. Bouras, and J.H. Morrison (1993) Calretinin-immunoreactive neocortical interneurons are unaffected in Alzheimer's disease. Neurosci. Lett. 152:145-149.
    • (1993) Neurosci. Lett. , vol.152 , pp. 145-149
    • Hof, P.R.1    Nimchinsky, E.A.2    Celio, M.R.3    Bouras, C.4    Morrison, J.H.5
  • 34
    • 0016541063 scopus 로고
    • The slow component of axonal transport
    • Hoffman, P.N., and R.J. Lasek (1975) The slow component of axonal transport. J. Cell Biol. 66:351-366.
    • (1975) J. Cell Biol. , vol.66 , pp. 351-366
    • Hoffman, P.N.1    Lasek, R.J.2
  • 35
    • 0021280389 scopus 로고
    • Control of axonal caliber by neurofilament transport
    • Hoffman, P.N., J.W. Griffin, and D.L. Price (1984) Control of axonal caliber by neurofilament transport. J. Cell Biol. 99:705-714.
    • (1984) J. Cell Biol. , vol.99 , pp. 705-714
    • Hoffman, P.N.1    Griffin, J.W.2    Price, D.L.3
  • 38
    • 0028085696 scopus 로고
    • The role of intracellular free calcium in motor neuron disease
    • Krieger, C., K. Jones, S.U. Kim, and A.A. Eisen (1994) The role of intracellular free calcium in motor neuron disease. J. Neurol. Sci. 124(Suppl):27-32.
    • (1994) J. Neurol. Sci. , vol.124 , Issue.SUPPL. , pp. 27-32
    • Krieger, C.1    Jones, K.2    Kim, S.U.3    Eisen, A.A.4
  • 39
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal, M., S. Pietri, M. Culcasi, and J. Bockaert (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364:535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 40
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death: Implication for the pathogenesis of human motor neuron disease
    • Lee, M.K., J.R. Marszalek, and D.W. Cleveland (1994) A mutant neurofilament subunit causes massive, selective motor neuron death: Implication for the pathogenesis of human motor neuron disease. Neuron 13:975-988.
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 41
    • 0023520075 scopus 로고
    • Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats
    • Lee, V.M., M.J. Carden, W.W. Schlaepfer, and J.Q. Trojanowski (1987) Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats. J. Neurosci. 7:3474-3488.
    • (1987) J. Neurosci. , vol.7 , pp. 3474-3488
    • Lee, V.M.1    Carden, M.J.2    Schlaepfer, W.W.3    Trojanowski, J.Q.4
  • 44
    • 0025999463 scopus 로고
    • Cytoskeletal pathology in motor neuron disease
    • L.P. Rowland (ed): New York: Raven Press, Ltd.
    • Leigh, P.N., and M. Swash (1991) Cytoskeletal pathology in motor neuron disease. In L.P. Rowland (ed): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York: Raven Press, Ltd., pp. 115-124.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 115-124
    • Leigh, P.N.1    Swash, M.2
  • 45
    • 0026486270 scopus 로고
    • Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis
    • Lledo, P.-M., B. Somasundaram, A.J. Morton, P.C. Emson, and W.T. Mason (1992) Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis. Neuron 9:943-954.
    • (1992) Neuron , vol.9 , pp. 943-954
    • Lledo, P.-M.1    Somasundaram, B.2    Morton, A.J.3    Emson, P.C.4    Mason, W.T.5
  • 46
    • 0028361193 scopus 로고
    • Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro
    • Lukas, W., and K.A. Jones (1994) Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro. Neuroscience 61:307-316.
    • (1994) Neuroscience , vol.61 , pp. 307-316
    • Lukas, W.1    Jones, K.A.2
  • 48
    • 0026069449 scopus 로고
    • Evidence for calcium-reducing and excitoprotective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons
    • Mattson, M.P., B. Rychlik, C. Chu, and S. Christakos (1991) Evidence for calcium-reducing and excitoprotective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons. Neuron 6:41-51.
    • (1991) Neuron , vol.6 , pp. 41-51
    • Mattson, M.P.1    Rychlik, B.2    Chu, C.3    Christakos, S.4
  • 49
    • 0023898954 scopus 로고
    • Neurofilament protein phosphorylation - Where, when and why
    • Matus, A. (1988) Neurofilament protein phosphorylation - Where, when and why. Trends Neurosci. 11:291-292.
    • (1988) Trends Neurosci. , vol.11 , pp. 291-292
    • Matus, A.1
  • 50
    • 0019878734 scopus 로고
    • The localization of motoneurons supplying the hindlimb muscles of the mouse
    • McHanwell, S., and T.J. Biscoe (1981) The localization of motoneurons supplying the hindlimb muscles of the mouse. Phil. Trans. R. Soc. London B 293:477-508.
    • (1981) Phil. Trans. R. Soc. London B , vol.293 , pp. 477-508
    • McHanwell, S.1    Biscoe, T.J.2
  • 51
    • 0024428392 scopus 로고
    • Focal accumulation of phosphorylated neurofilaments within anterior horn cell in familial amyotrophic lateral sclerosis
    • Mizusawa, H., S. Matsumoto, S.-H. Yen, A. Hirano, R.R. Rojas-Corona, and H. Donnenfeld (1989) Focal accumulation of phosphorylated neurofilaments within anterior horn cell in familial amyotrophic lateral sclerosis. Acta Neuropathol. 79:37-43.
    • (1989) Acta Neuropathol. , vol.79 , pp. 37-43
    • Mizusawa, H.1    Matsumoto, S.2    Yen, S.-H.3    Hirano, A.4    Rojas-Corona, R.R.5    Donnenfeld, H.6
  • 52
    • 0028198969 scopus 로고
    • Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D-28k
    • Mockel, V., and G. Fischer (1994) Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D-28k. Brain Res. 648:109-120.
    • (1994) Brain Res. , vol.648 , pp. 109-120
    • Mockel, V.1    Fischer, G.2
  • 53
    • 0023278930 scopus 로고
    • A monoclonal antibody to nonphosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease
    • Morrison, J.H., D.A. Lewis, M.J. Campbell, G.W. Huntley, D.L. Benson, and C. Bouras (1987) A monoclonal antibody to nonphosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease. Brain Res. 416:331-336.
    • (1987) Brain Res. , vol.416 , pp. 331-336
    • Morrison, J.H.1    Lewis, D.A.2    Campbell, M.J.3    Huntley, G.W.4    Benson, D.L.5    Bouras, C.6
  • 54
    • 0023738527 scopus 로고
    • Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients
    • Munoz, D.G., F.R.C.P.(C), C. Greene, D.P. Perl, and D.J. Selkoe (1988) Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients. J. Neuropathol. Exp. Neurol. 47:9-18.
    • (1988) J. Neuropathol. Exp. Neurol. , vol.47 , pp. 9-18
    • Munoz, D.G.1    Greene, C.2    Perl, D.P.3    Selkoe, D.J.4
  • 55
    • 0020535775 scopus 로고
    • Motor neuron columns in the lumbar spinal cord of the rat
    • Nicolopoulos-Stournaras, S., and J.F. Iles (1983) Motor neuron columns in the lumbar spinal cord of the rat. J. Comp. Neurol. 217:75-85.
    • (1983) J. Comp. Neurol. , vol.217 , pp. 75-85
    • Nicolopoulos-Stournaras, S.1    Iles, J.F.2
  • 56
    • 0024560042 scopus 로고
    • Evidence for sequential degeneration of the neurons in the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: A topographic and quantitative investigation
    • Oyanagi, K., F. Ikuta, and Y. Horikawa (1989) Evidence for sequential degeneration of the neurons in the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: A topographic and quantitative investigation. Acta Neuropathol. 77:343-349.
    • (1989) Acta Neuropathol. , vol.77 , pp. 343-349
    • Oyanagi, K.1    Ikuta, F.2    Horikawa, Y.3
  • 57
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo, C.A., Z. Xu, D.R. Borchelt, D.L. Price, S.S. Sisodia, and D.W. Cleveland (1995) Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc. Natl. Acad. Sci. USA 92:954-958.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3    Price, D.L.4    Sisodia, S.S.5    Cleveland, D.W.6
  • 58
    • 0025934141 scopus 로고
    • Altered glutamatergic mechanisms and selective motor neuron degeneration in amyotrophic lateral sclerosis
    • L.P. Rowland (ed): New York: Raven Press, Ltd.
    • Plaitakis, A. (1991) Altered glutamatergic mechanisms and selective motor neuron degeneration in amyotrophic lateral sclerosis. In L.P. Rowland (ed): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York: Raven Press, Ltd., pp. 319-326.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 319-326
    • Plaitakis, A.1
  • 59
    • 0028303110 scopus 로고
    • A comparative study of the calcium-binding proteins calbindin-D28k, calretinin, calmodulin and parvalbumin in the rat spinal cord
    • Ren, K., and M.A. Ruda (1994) A comparative study of the calcium-binding proteins calbindin-D28k, calretinin, calmodulin and parvalbumin in the rat spinal cord. Brain Res. Rev. 19:163-179.
    • (1994) Brain Res. Rev. , vol.19 , pp. 163-179
    • Ren, K.1    Ruda, M.A.2
  • 60
    • 0026567734 scopus 로고
    • Calretinin in rat brain: An immunohistochemical study
    • Resibois, A., and J.H. Rogers (1992) Calretinin in rat brain: An immunohistochemical study. Neuroscience 46:101-134.
    • (1992) Neuroscience , vol.46 , pp. 101-134
    • Resibois, A.1    Rogers, J.H.2
  • 61
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps, M.E., G.W. Huntley, P.R. Hof, J.H. Morrison, and J.W. Gordon (1995) Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 92:689-693.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 64
    • 0027274623 scopus 로고
    • Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity
    • Rothstein, J.D., L. Jin, M. Dykes-Hoberg, and R.W. Kuncl (1993) Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natl. Acad. Sci. USA 90:6591-6595.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6591-6595
    • Rothstein, J.D.1    Jin, L.2    Dykes-Hoberg, M.3    Kuncl, R.W.4
  • 65
    • 0020038258 scopus 로고
    • Immunoelectronmicroscopical localization of the three neurofilament triplet proteins along neurofilaments of cultured dorsal root ganglion neurones
    • Sharp, G.A., G. Shaw, and K. Weber (1982) Immunoelectronmicroscopical localization of the three neurofilament triplet proteins along neurofilaments of cultured dorsal root ganglion neurones. Exp. Cell Res. 137:403-413.
    • (1982) Exp. Cell Res. , vol.137 , pp. 403-413
    • Sharp, G.A.1    Shaw, G.2    Weber, K.3
  • 66
    • 0000994037 scopus 로고
    • Neurofilament proteins
    • R.D. Burgoyne (ed): New York: Wiley-Liss, Inc.
    • Shaw, G. (1991) Neurofilament proteins. In R.D. Burgoyne (ed): The Neuronal Cytoskeleton. New York: Wiley-Liss, Inc., pp. 185-214.
    • (1991) The Neuronal Cytoskeleton , pp. 185-214
    • Shaw, G.1
  • 69
    • 0028194834 scopus 로고
    • Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line
    • Smith, R.G., M.E. Alexianu, G. Crawford, O. Nyormoi, E. Stefani, and S.H. Appel (1994) Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line. Proc. Natl. Acad. Sci. USA 91:3393-3397.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3393-3397
    • Smith, R.G.1    Alexianu, M.E.2    Crawford, G.3    Nyormoi, O.4    Stefani, E.5    Appel, S.H.6
  • 70
    • 0002918293 scopus 로고
    • Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
    • Sternberger, L.A., and N.H. Sternberger (1983) Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc. Natl. Acad. Sci. USA 80:6126-6130.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6126-6130
    • Sternberger, L.A.1    Sternberger, N.H.2
  • 71
    • 0002634911 scopus 로고
    • Clinical features and differential diagnosis of classical motor neuron disease
    • A.C. Williams (ed): London: Chapman and Hall
    • Tandan, R. (1994) Clinical features and differential diagnosis of classical motor neuron disease. In A.C. Williams (ed): Motor Neuron Disease. London: Chapman and Hall, pp. 3-28.
    • (1994) Motor Neuron Disease , pp. 3-28
    • Tandan, R.1
  • 72
    • 0028325407 scopus 로고
    • Disease-specific patterns of neuronal loss in the spinal ventral horn in amyotrophic lateral sclerosis, multiple system atrophy and x-linked recessive bulbospinal neuronopathy, with special reference to the loss of small neurons in the intermediate zone
    • Terao, S., G. Sobue, Y. Hashizume, T. Mitsuma, and A. Takahashi (1994) Disease-specific patterns of neuronal loss in the spinal ventral horn in amyotrophic lateral sclerosis, multiple system atrophy and x-linked recessive bulbospinal neuronopathy, with special reference to the loss of small neurons in the intermediate zone. J. Neurol. 241:196-203.
    • (1994) J. Neurol. , vol.241 , pp. 196-203
    • Terao, S.1    Sobue, G.2    Hashizume, Y.3    Mitsuma, T.4    Takahashi, A.5
  • 73
    • 0022623396 scopus 로고
    • Expression of neurofilament subunits in neurons of the central and peripheral nervous system: An immunohistochemical study with monoclonal antibodies
    • Trojanowski, J.Q., N. Walkenstein, and V.M.-Y. Lee (1986) Expression of neurofilament subunits in neurons of the central and peripheral nervous system: An immunohistochemical study with monoclonal antibodies. J. Neurosci. 6:650-660.
    • (1986) J. Neurosci. , vol.6 , pp. 650-660
    • Trojanowski, J.Q.1    Walkenstein, N.2    Lee, V.M.-Y.3
  • 74
    • 0026452101 scopus 로고
    • Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis
    • Troost, D., P.A.E. Sillevis Smitt, J.M.B.V. de Jong, and D.F. Swaab (1992) Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis. Acta Neuropathol. 84:664-673.
    • (1992) Acta Neuropathol. , vol.84 , pp. 664-673
    • Troost, D.1    Sillevis Smitt, P.A.E.2    De Jong, J.M.B.V.3    Swaab, D.F.4
  • 75
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu, P.-H., P. Raju, K.A. Robinson, M.E. Gurney, J.Q. Trojanowski, and V.M.-Y. Lee (1996) Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. USA 93:3155-3160.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3155-3160
    • Tu, P.-H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.-Y.6
  • 76
    • 0026634688 scopus 로고
    • The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig
    • Vickers, J.C., and M. Costa (1992) The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig. Neuroscience 49:73-100.
    • (1992) Neuroscience , vol.49 , pp. 73-100
    • Vickers, J.C.1    Costa, M.2
  • 77
    • 0026041623 scopus 로고
    • Slow non-NMDA receptor mediated neurotoxicity and amyotrophic lateral sclerosis
    • L.P. Rowland (ed): New York: Raven Press, Ltd.
    • Weiss, J.H., and D.W. Choi (1991) Slow non-NMDA receptor mediated neurotoxicity and amyotrophic lateral sclerosis. In L.P. Rowland (ed): Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. New York: Raven Press, Ltd., pp. 311-318.
    • (1991) Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases , pp. 311-318
    • Weiss, J.H.1    Choi, D.W.2
  • 78
    • 0027194462 scopus 로고
    • New stereological methods for counting neurons
    • West, M.J. (1993) New stereological methods for counting neurons. Neurobiol. Aging 14:275-285.
    • (1993) Neurobiol. Aging , vol.14 , pp. 275-285
    • West, M.J.1
  • 79
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West, M.J., L. Slomianka, and H.J.G. Gundersen (1991) Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231:482-497.
    • (1991) Anat. Rec. , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.G.3
  • 81
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong, P.C., C.A. Pardo, D.H. Borchelt, M.K. Lee, N.G. Copeland, N.A. Jenkins, S.S. Sisodia, D.W. Cleveland, and D.L. Price (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.H.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 82
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu, Z., L.C. Cork, J.W. Griffin, and D.W. Cleveland (1993) Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73:23-33.
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.