Mechanisms regulating the vascular smooth muscle Na/H exchanger (NHE-1) in diabetes

Biochemistry and Cell Biology

Volumn 76, Issue 5, 1998, Pages 751-759

  Hannan, Katherine M ^a   Little, Peter J ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

Complications; Diabetes; Sodium hydrogen exchanger; Vascular smooth muscle

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ANTIPORTER; DIACYLGLYCEROL; GLUCOSE; GROWTH FACTOR; INSULIN; SOMATOMEDIN C;

CELL PROLIFERATION; CONFERENCE PAPER; DIABETIC ANGIOPATHY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MOLECULAR MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; PROTON SODIUM EXCHANGE; VASCULAR SMOOTH MUSCLE;

EID: 0032467165     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o98-093     Document Type: Conference Paper

References (81)

1. + exchanger in renal microvillus membrane vesicles. Nature (London), 299: 161-163.
2. 2+-binding protein, p22, is required for constitutive membrane traffic. J. Biol. Chem. 271: 10 183-10 187.
3. Begum, N., Song, Y., Rienzie, J., and Ragolia, L. 1998. Vascular smooth muscle cell growth and insulin regulation of mitogen-activated protein kinase in hypertension. Am. J. Physiol. 275: C42-C49.
4. Berk, B.C., Canessa, M., Vallega, G., and Alexander, R.W. 1988. Agonist-mediated changes in intracellular pH: role in vascular smooth muscle cell function. J. Cardiovasc. Pharmacol. 12: S104-S114.
5. + exchanger gene expression: mitogenic stimulation increases NHE1 promoter activity. Am. J. Physiol. 274: C831-C839.
6. +-exchanger (NHE-1 isoform) in response to growth factors. J. Biol. Chem. 272: 271-279.
7. Bobik, A., Weissberg, P.L., and Little, P.J. 1987. Regulation of sodium influx and sodium, potassium pump activity by a sodium-hydrogen antiport in rat vascular smooth muscle. Clin. Exp. Pharmacol. Physiol. 14: 191-195.
8. Bobik, A., Grooms, A., Little, P.J., Cragoe, E.J., Jr., and Grinpukel, S. 1991. Ethyisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle cell growth. Am. J. Physiol. 260: C581-C588.
9. Cagliero, E., Roth, T., Taylor, A.W., and Lorenzi, M. 1995. The effects of high glucose on human endothelial cell growth and gene expression are not mediated by transforming growth factor-beta. Lab. Invest. 73: 667-673.
10. Cavalot, F., Anfossi, G., Russo, I., Mularoni, E., Massucco, P., Mattiello, L., Burzacca, S., Hahn, A.W., and Trovati, M. 1996. Nonenzymatic glycation of fibronectin impairs adhesive and proliferative properties of human vascular smooth muscle cells. Metab. Clin. Exp. 45: 285-292.
11. + exchange. Am. J. Physiol. 272: C818-C826.
12. Ceriello, A., Falleti, E., Motz, E., Taboga, C., Tonutti, L., Ezsol, Z., Gonano, F., and Bartoli, E. 1998. Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: the possible role of oxidative stress. Horm. Metab. Res. 30: 146-149.
13. Chappey, O., Dosquet, C., Wautier, M.-P., and Wautier, J.-L. 1997. Advanced glycation end products, oxidant stress and vascular lesions. Eur. J. Clin. Invest. 27: 97-108.
14. Counillon, L., and Pouyssegur, J. 1995. Structure-function studies and molecular regulation of the growth factor activatable sodium-hydrogen exchanger (NHE-1). Cardiovasc. Res. 29: 147-154.
15. + exchanger-1. Biochemistry, 36: 2951-2959.
16. Cox, G.A., Lutz, C.M., Yang, C.-L., Biemesderfer, D., Bronson, R.T., Fu, A., Aronson, P.S., Noebels, J.L., and Frankel, W.N. 1997. Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell, 91: 139-148.
17. Cruzado, M., Risler, N., Castro, C., and Ruttler, M.E. 1998. Proliferative effect of insulin on cultured smooth muscle cells from rat mesenteric resistance vessels. Am. J. Hypertens. 11: 54-58.
18. + exchange. J. Gen. Physiol. 109: 117-128.
19. Derkert, T., Poulsen, J.E., and Larsen, M. 1978. Prognosis of diabetes onset before the age of thirty-one. II. Factors influencing the prognosis. Diabetologia, 14: 371-377.
20. Diabetes Control and Complications Trial Research Group. 1993. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes. N. Engl. J. Med. 329: 977-986.
21. Erlinge, D. 1998. Extracellular ATP: a growth factor for vascular smooth muscle cells. Gen. Pharmacol. 31: 1-8.
22. Fliegel, L., and Dyck, J.R.B. 1995. Molecular biology of the cardiac sodium/hydrogen exchanger. Cardiovasc. Res. 29: 155-159.
23. Giugliano, D., Ceriello, A., and Paolisso, G. 1996. Oxidative stress and diabetic vascular complications. Diabetes Care, 19: 257-267.
24. Igarashi, M., Takeda, Y., Ishibashi, N., Mori, S., Tominaga, M., and Saito, Y 1997. Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterization. Horm. Metab. Res. 29: 444-449.
25. + exchanger (NHE-1): pH-maintenance, ATP-sensitive, and flexible loop domains. J. Biochem. (Tokyo), 121: 295-303.
26. Incerpi, S., Rizvi, S.I., De Vito, P., and Luly, P. 1997. Insulin stimulation of Na/H antiport in L-6 cells: a different mechanism in myoblasts and myotubes. J. Cell Physiol. 171: 235-242.
27. Ishii, H., Koya, D., and King, G.L. 1998. Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus. J. Mol. Med. 76: 21-31.
28. Jensen-Urstad, K.J., Reichard, P.G., Rosfors, J.S., Lindblad, L.E., and Jensen-Urstad, M.T. 1996. Early atherosclerosis is retarded by improved long-term blood glucose control in patients with IDDM. Diabetes, 45: 1253-1258.
29. Johnson, D., Brew, B., Poronnik, P., Cook, D.I., Field, M.J., Gyory, A.Z., and Pollock, C.A. 1997. Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells. Am. J. Physiol. 272: F484-F490.
30. Kornowski, R., Mintz, G.S., Kent, K.M., Pichard, A.D., Satler, F., Bucher, T.A., Hong, M.K., Popma, J.J., and Leon, M.B. 1997. Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia. Circulation, 95: 1366-1369.
31. + exchange. Circ. Res. 73: 264-268.
32. Krolewski, A.S., Warram, J.H., Valsania, P., Martin, B.C., Laffel, L.M.B., and Christlieb, A.R. 1991. Evolving natural history of coronary artery disease in diabetes mellitus. Am. J. Med. 90: 56S-61S.
33. Kusuhara, M., Chait, A., Cader, A., and Berk, B.C. 1997. Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages. Arterioscler. Thromb. Vasc. Biol. 17: 141-148.
34. Lin, X., and Barber, D.L. 1996. A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. Proc. Natl. Acad. Sci. U.S.A. 93: 12 631-12 636.
35. Little, P.J., Cragoe, E.J., Jr., and Bobik, A. 1986. Na-H exchange is a major pathway for Na influx in rat vascular smooth muscle. Am. J. Physiol. 251: C707-E712.
36. + antiport activation in cultured rat aortic smooth muscle on calmodulin, calcium, and ATP. J. Biol. Chem. 263: 16 780-16 786.
37. - mechanisms. Cardiovasc. Res. 29: 239-246.
38. Lucchesi, P.A., and Berk, B.C. 1995. Regulation of sodium-hydrogen exchange in vascular smooth muscle. Cardiovasc. Res. 29: 172-177.
39. + exchanger-1 alleles: strain distribution and correlation with activity. Immunogenetics, 43: 163-164.
40. + exchange in vascular smooth muscle cells: role of protein kinase C. Am. J. Physiol. 260: C562-C569.
41. + exchange inhibitors decrease neointimal formation after rat carotid injury. Effects on smooth muscle cell migration and proliferation. Circ. Res. 73: 269-275.
42. + exchange activity. Proc. Natl. Acad. Sci. U.S.A. 91: 5898-5902.
43. Morishita, R., Nakamura, S., Nakamura, Y., Aoki, M., Moriguchi, A., Kida, I., Yo, Y., Matsumoto, K., Nakamura, T., Higaki, J., and Ogihara, T. 1997. Potential role of an endothelium-specific growth factor, heptocyte growth factor, on endothelial damage in diabetes. Diabetes, 46: 138-142.
44. Murer, H., Hopfer, U., and Kinne, R. 1976. Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney. Biochem. J. 154: 597-604.
45. Natarajan, R., Lanting, L., Gonzales, N., and Nadler, J. 1996. Formation of an F2-isoprostane in vascular smooth muscle cells by elevated glucose and growth factors. Am. J. Physiol. 271: H159-H165.
46. + antiporter phenotype and turnover of immortalized lymphoblasts from type 1 diabetic patients with nephropathy. J. Clin. Invest. 93: 2750-2757.
47. + antiport in human platelets. Circulation, 95: 1370-1377.
48. Pfeiffer, A., and Schatz, H. 1995. Diabetic microvascular complications and growth factors. Exp. Clin. Endocrinol. Diabetes, 103: 7-14.
49. + exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells. Hypertension (Dallas), 29: 1265-1272.
50. Pugliese, G., Pricci, F., Romeo, G., Pugliese, F., Mene, P., Giannini, S., Cresci, B., Galli, G., Rotella, C.M., Vlassara, H., and Di Mario, U. 1997. Upregulation of mesangial growth factor and extracellular matrix synthesis by advanced glycation end products via a receptor-mediated mechanism. Diabetes, 46: 1881-1887.
51. + antiporter gene expression in vascular smooth muscle cells by hypertrophic and hyperplastic stimuli. J. Biol. Chem. 265: 19 393-19 396.
52. Rumble, J.R., Cooper, M.E., Soulis, T., Cox, A., Wu, L., Youssef, S., Jasik, M., Jerums, G., and Gilbert, R.E. 1997. Vascular hypertrophy in experimental diabetes: role of advanced glycation products. J. Clin. Invest. 99: 1016-1027.
53. + exchange in neonatal rat cardiac myocytes. Circ. Res. 82: 1053-1062.
54. Satoh, H., Togo, M., Hara, M., Miyata, T., Han, K., Maekawa, H., Ohno, M., Hashimoto, Y., Kurokawa, K., and Watanabe, T. 1997. Advanced glycation end products stimulate mitogen-activated protein kinase and proliferation in rabbit vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 239: 111-115.
55. Sayeski, P.P., and Kudlow, J.E. 1996. Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-alpha gene transcription. J. Biol. Chem. 271: 15 237-15 243.
56. Semplicini, A., Ceolotto, G., Felice, M., Bordin, L., Monari, A., Clari, G., and Pessina, A.C. 1996. Posttranslational effects of protein kinase C and insulin on red cell membrane phosphorylation and cation heteroexchange in hypertension. Blood Press. 1: 55-58.
57. + exchanger isoform 1 in human fibroblasts. Biochem. Biophys. Res. Commun. 209: 191-197.
58. + exchanger, NHE-1, in vascular myocytes from Wistar-Kyoto and spontaneously hypertensive rats. Metab. Clin. Exp. 45: 114-119.
59. + exchanger isoform 1 phosphorylation in normal Wistar-Kyoto and spontaneously hypertensive rats. Circ. Res. 76: 825-831.
60. + exchanger isoform-1. Metab. Clin. Exp. 46: 250-256.
61. + exchange in hypertension and in diabetes mellitus: facts and hypotheses. Basic Res. Cardiol. 91: 179-190.
62. + exchange and protein kinase C in aortic smooth muscle cells. Circ. Res. 76: 530-535.
63. Sowers, J.R. 1996. Effects of insulin and IGF-1 on vascular smooth muscle glucose and cation metabolism. Diabetes, 45: S47-S51.
64. Standley, P.R., Zhang, F., Zayas, R.M., Muniyappa, R., Walsh, M.F., Cragoe, E., and Sowers, J.R. 1997. IGF-1 regulation of Na(+)-K(+)-ATPase in rat arterial smooth muscle. Am. J. Physiol. 273: E113-E121.
65. Stiernberg, J., LaBelle, E., and Carney, D.H. 1983. Demonstration of a late amiloride-sensitive event as a necessary step in initiation of DNA synthesis by thrombin. J. Cell. Physiol. 117: 272-281.
66. + exchanger kinase. Circ. Res. 81: 268-273.
67. + antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system. J. Mol. Cell. Cardiol. 27: 729-742.
68. Touyz, R.M., and Schiffrin, E.L. 1997. Growth factors mediate intracellular signalling in vascular smooth muscle cells through protein kinase C-linked pathways. Hypertension (Dallas), 30: 1440-1447.
69. Voyno-Yasetskaya, T., Conklin, B.R., Gilbert, R.L., Hooley, R., Bourne, H.R., and Barber, D.L. 1994. Gα13 stimulates Na-H exchange. J. Biochem. 269: 4721-4724.
70. Vranes, D., Cooper, M.E., and Dilley, R.J. 1995. Angiotensin-converting enzyme inhibition reduces diabetes-induced vascular hypertrophy: morpholometric studies. J. Vasc. Res. 32: 183-189.
71. + exchanger NHE-1 through sequence-specific interaction. Biochemistry, 36: 12 854-12 861.
72. + exchanger through mitogen-activated protein kinase. Biochemistry, 36: 9151-9158.
73. + antiporter potentiates growth and retinoic acid-induced differentiation of P19 embryonal carcinoma cells. J. Biol. Chem. 272: 26 545-26 549.
74. + exchanger expression. Mol. Cell. Biochem. 176: 99-106.
75. Weissberg, P.L., Little, P.J., Cragoe, E.J., Jr., and Bobik, A. 1987. Na-H antiport in cultured rat aortic smooth muscle: its role in cytoplasmic pH regulation. Am. J. Physiol. 253: C193-C198.
76. + antiport activity and gene expression in cultured vascular smooth muscle cells. J. Clin. Invest. 93: 2623-2631.
77. Yang, W., Dyck, J.R.B., and Fliegel, L. 1996a. Regulation of NHE-1 expression in L6 muscle cells. Biochim. Biophys. Acta, 1306: 107-113.
78. Yang, W., Dyck, J.R.B., Wang, H., and Fliegel, L. 1996b. Regulation of NHE-1 promoter in mammalian myocardium. Am. J. Physiol. 270: H259-H266.
79. + exchanger isoform (NHE-2). Biochem. Biophys. Res. Commun. 193: 532-539.
80. + exchanger gene family: structure and function studies. Am. J. Physiol. 269: G1-G11.
81. Zaidi, K.F., and Yudkin, J.S. 1996. Characteristics of the sodium/ hydrogen exchange in non-insulin-dependent diabetic patients with microalbuminuria and hypertension. Clin. Sci. 90: 13-19.