Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells

American Journal of Physiology - Renal Physiology

Volumn 272, Issue 4 41-4, 1997, Pages

  Johnson, David W ^a   Brew, Bronwyn K ^a   Poronnik, Philip ^a   Cook, David I ^a   Field, Michael J ^a   Györy, Akos Z ^a   Pollock, Carol A ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Intracellular pH; Kidney tubules; Microspectrofluorometry; Proximal tubule physiology; Sodium hydrogen antiporter

Indexed keywords

SOMATOMEDIN C;

ARTICLE; CELL PH; CELL STIMULATION; EPITHELIUM CELL; GLYCOSYLATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MICROFLUOROMETRY; NEPHROTOXICITY; PATHOGENESIS; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SODIUM TRANSPORT;

EID: 0030772356     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1997.272.4.f484     Document Type: Article

References (30)

1. Amemiya, M., J. Loffing, M. Lotscher, B. Kaissling, R. J. Alpern, and O. W. Moe. Expression of NHE- 3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int. 48: 1206-1215, 1995.
2. Baxter, R. C. Insulin-like growth factor binding proteins in the human circulation: a review. Horm. Res. 42: 140-144, 1994.
3. + transport. Am. J. Physiol. 255 (Cell Physiol. 24): C413-C417, 1988.
4. Boogaard, P. J., J. F. Nagelkerke, and G. J. Mulder. Renal proximal tubular cells in suspension or in primary culture as in vitro models to study nephrotoxicity. Chem. Biol. Interact. 76: 251-291, 1990.
5. + exchange activity in LLC-PK1/ PKE20 cells. II. Hormonal regulation. Pflügers Arch. 420: 282-289, 1992.
6. i transport in cultured kidney cells. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F712-F717, 1989.
7. Fine, L. G. The biology of renal hypertrophy. Kidney Int. 29: 619-634, 1986.
8. Fine, L. G., and J. T. Norman. Renal growth responses to acute and chronic injury: routes to therapeutic intervention. J. Am. Soc. Nephrol. 2: S206-S211, 1992.
9. Flyvbjerg, A., O. Thorlacius Ussing, R. Naeraa, J. Ingerslev, and H. Orskov. Kidney tissue somatomedin C and initial renal growth in diabetic and uninephrectomized rats. Diabetologia 31: 310-314, 1988.
10. + exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim. Biophys. Acta 988: 73-97, 1989.
11. Guler, H. P., K. U. Eckardt, J. Zapf, C. Bauer, and E. R. Froesch. Insulin-like growth factor I increase glomerular filtration rate and renal plasma flow in man. Acta Endocrinol. Copenhagen 121: 101-106, 1989.
12. Haggerty, J. G., N. Agarwal, R. F. Reilly, E. A. Adelberg, and C. W. Slayman. Pharmacologically different Na/H antiporters on the apical and basolateral surfaces of cultured porcine kidney cells (LLC-PK1). Proc. Natl. Acad. Sci. USA 85: 6797-6801, 1988.
13. Hammerman, M. R., and S. B. Miller. The growth hormone insulin-like growth factor axis in kidney revisited. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F1-F14, 1993.
14. Handler, J. S., F. M. Perkins, and J. P. Johnson. Studies of renal cell function using cell culture techniques. Am. J. Physiol. 238 (Renal Fluid Electrolyte Physiol. 7): F1-F9, 1980.
15. Johnson, D. W., B. K. Brew, P. Poronnik, D. I. Cook, M. J. Field, and C. A. Pollock. Transport characteristics of human proximal tubule cells in primary culture. Nephrology. In press.
16. Krieg, R., F. Santos, and J. Chan. Growth hormone, insulin-like growth factor and the kidney. Kidney Int. 48: 321-336, 1995.
17. + exchangers stably expressed in a fibroblast cell line. J. Biol. Chem. 268: 25527-25535, 1993.
18. + exchange is not required for induction of hypertrophy of renal cells in vitro. J. Am. Soc. Nephrol. 3: 1124-1130, 1992.
19. Mellas, J., J. R. Gavin, and M. R. Hammerman. Multiplication-stimulating activity-induced alkalinization of canine renal proximal tubular cells. J. Biol. Chem. 261: 14437-14442, 1986.
20. + exchange in cultured opossum kidney cells. Am. J. Physiol. 259 (Cell Physiol. 28): C121-C133, 1990.
21. Murer, H., R. Krapf, and C. Heimle Kolb. Regulation of renal proximal tubular Na/H-exchange: a tissue culture approach. Kidney Int. 44: S23-S31, 1994.
22. Negulescu, P. A., and T. E. Machen. Intracellular ion activities and membrane transport in parietal cells measured with fluorescent dyes. Methods Enzymol. 192: 38-81, 1990.
23. + exchanger isoforms. Am. J. Physiol. 268 (Cell Physiol. 37): C283-C296, 1995.
24. Pollock, C. A., and M. J. Field. Compensatory renal hypertrophy: tubular cell growth and transport studied in primary culture. Nephron 64: 615-620, 1993.
25. 3 symporter activities in chronic hyperfiltration. A model of cell hypertrophy. J. Gen. Physiol. 97: 195-217, 1991.
26. Roos, A., and W. F. Boron. Intracellular pH. Physiol. Rev. 61: 296-434, 1981.
27. + exchanger isoform NHE-3 in rabbit and canine kidney. Biochim. Biophys. Acta 1195: 89-95, 1994.
28. + exchanger isoform (NHE-2). J. Biol. Chem. 268: 11917-11924, 1993.
29. + exchanger isoform NHE-2 in rat kidney with confocal fluorescence microscopy (Abstract). FASEB J. 10: 370, 1996.
30. Yun, C. H., C. M. Tse, S. Nath, S. L. Levine, and M. Donowitz. Structure/function studies of mammalian Na-H exchangers: an update. J. Physiol. (Lond.) 482: 1S-6S, 1995.