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Volumn 138, Issue 1, 1997, Pages 307-313

Human insulin-like growth factor I (IGF-I) produced in the mammary glands of transgenic rabbits: Yield, receptor binding, mitogenic activity, and effects on IGF-binding proteins

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

EID: 0031014901     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.1.4877     Document Type: Article
Times cited : (59)

References (39)
  • 2
    • 0027429427 scopus 로고
    • Growth hormone insensitivity syndromes: A preliminary report on changes in insulin-like growth factors and their binding proteins during treatment with recombinant insulin-like growth factor 1
    • Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes
    • Blum WF, Hall K, Ranke MB, Wilton P 1993 Growth hormone insensitivity syndromes: a preliminary report on changes in insulin-like growth factors and their binding proteins during treatment with recombinant insulin-like growth factor 1. Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes. Acta Paediatr [Suppl 82] 391:15-19
    • (1993) Acta Paediatr , vol.391 , Issue.82 SUPPL. , pp. 15-19
    • Blum, W.F.1    Hall, K.2    Ranke, M.B.3    Wilton, P.4
  • 3
    • 0027131718 scopus 로고
    • The composition and distribution of insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) in the serum of growth hormone receptor-deficient patients: Effects of IGF-1 therapy on IGFBP-3
    • Gargosky SE, Wilson KF, Fielder PJ, Vaccarello MA, Guevara Aguirre J, Diamond FB, Baxter RC, Rosenbloom AL, Rosenfeld RG 1993 The composition and distribution of insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) in the serum of growth hormone receptor-deficient patients: effects of IGF-1 therapy on IGFBP-3. J Clin Endocrinol Metab 77:1683-1689
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1683-1689
    • Gargosky, S.E.1    Wilson, K.F.2    Fielder, P.J.3    Vaccarello, M.A.4    Guevara Aguirre, J.5    Diamond, F.B.6    Baxter, R.C.7    Rosenbloom, A.L.8    Rosenfeld, R.G.9
  • 5
    • 0027370551 scopus 로고
    • Body fat in Laron syndrome patients: Effect of insulin-like growth factor I treatment
    • Laron Z, Klinger B 1993 Body fat in Laron syndrome patients: effect of insulin-like growth factor I treatment. Horm Res 40:16-22
    • (1993) Horm Res , vol.40 , pp. 16-22
    • Laron, Z.1    Klinger, B.2
  • 6
    • 0027135071 scopus 로고
    • Therapeutic potential of rhIGF-I in diabetes and conditions of insulin resistance
    • Froesch ER, Hussain M 1993 Therapeutic potential of rhIGF-I in diabetes and conditions of insulin resistance. J Intern Med 234:561-570
    • (1993) J Intern Med , vol.234 , pp. 561-570
    • Froesch, E.R.1    Hussain, M.2
  • 7
    • 0027141307 scopus 로고
    • Short-term effects of recombinant human insulin-like growth factor I on metabolic control of patients with type II diabetes mellitus
    • Schalch DS, Turman NJ, Marcsisin VS, Heffernan M, Guler HP 1993 Short-term effects of recombinant human insulin-like growth factor I on metabolic control of patients with type II diabetes mellitus. J Clin Endocrinol Metab 77:1563-1568
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1563-1568
    • Schalch, D.S.1    Turman, N.J.2    Marcsisin, V.S.3    Heffernan, M.4    Guler, H.P.5
  • 8
    • 0028123307 scopus 로고
    • Insulin-like growth factor-1 therapy in diabetes: Physiologic basis, clinical benefits, and risks
    • Kolaczynski JW, Caro JF 1994 Insulin-like growth factor-1 therapy in diabetes: physiologic basis, clinical benefits, and risks. Ann Intern Med 120:47-55
    • (1994) Ann Intern Med , vol.120 , pp. 47-55
    • Kolaczynski, J.W.1    Caro, J.F.2
  • 9
    • 0027501201 scopus 로고
    • Acquired growth hormone resistance in patients with hypercatabolism
    • Bentham J, Rodriguez Arnao J, Ross RJ 1993 Acquired growth hormone resistance in patients with hypercatabolism. Horm Res 40:87-91
    • (1993) Horm Res , vol.40 , pp. 87-91
    • Bentham, J.1    Rodriguez Arnao, J.2    Ross, R.J.3
  • 10
    • 0027954321 scopus 로고
    • Anabolic effects of recombinant insulin-like growth factor-1 in cachectic patients with the acquired immunodeficiency syndrome
    • Lieberman SA, Butterfield GE, Harrison D, Hoffman AR 1994 Anabolic effects of recombinant insulin-like growth factor-1 in cachectic patients with the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 78:404-410
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 404-410
    • Lieberman, S.A.1    Butterfield, G.E.2    Harrison, D.3    Hoffman, A.R.4
  • 11
    • 0027786850 scopus 로고
    • Insulin-like growth factor 1 and endotoxin-mediated kidney dysfunction in critically ill, parenterally fed rats
    • Manzo CB, Dickerson RN, Settle RG, Rajter JJ 1993 Insulin-like growth factor 1 and endotoxin-mediated kidney dysfunction in critically ill, parenterally fed rats. Nutrition 9:528-531
    • (1993) Nutrition , vol.9 , pp. 528-531
    • Manzo, C.B.1    Dickerson, R.N.2    Settle, R.G.3    Rajter, J.J.4
  • 12
    • 0027376084 scopus 로고
    • Formation-stimulating regimens other than sodium fluoride
    • Riggs BL 1993 Formation-stimulating regimens other than sodium fluoride. Am J Med 95:62S-68S
    • (1993) Am J Med , vol.95
    • Riggs, B.L.1
  • 13
    • 85047680306 scopus 로고
    • Improvement of doxorubicin induced cardiomyopathy in rats treated with insulin-like growth factor 1
    • Ambler GR, Johnston BM, Maxwell L, Gavin JB, Gluckman PD 1993 Improvement of doxorubicin induced cardiomyopathy in rats treated with insulin-like growth factor 1. Cardiovasc Res 27:1368-1373
    • (1993) Cardiovasc Res , vol.27 , pp. 1368-1373
    • Ambler, G.R.1    Johnston, B.M.2    Maxwell, L.3    Gavin, J.B.4    Gluckman, P.D.5
  • 14
    • 0027756168 scopus 로고
    • Trophic support of motoneurons: Physiological, pathophysiological, and therapeutic implications
    • Thoenen H, Hughes RA, Sendtner M 1993 Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications. Exp Neurol 124:47-55
    • (1993) Exp Neurol , vol.124 , pp. 47-55
    • Thoenen, H.1    Hughes, R.A.2    Sendtner, M.3
  • 16
    • 0027940365 scopus 로고
    • Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits
    • Brem G, Hartl P, Besenfelder U, Wolf E, Zinovieva N, Pfaller R 1994 Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits. Gene 149:351-355
    • (1994) Gene , vol.149 , pp. 351-355
    • Brem, G.1    Hartl, P.2    Besenfelder, U.3    Wolf, E.4    Zinovieva, N.5    Pfaller, R.6
  • 17
    • 0028379864 scopus 로고
    • Radioimmunoassays for insulin-like growth factors and their binding proteins
    • Blum WF, Breier BH 1994 Radioimmunoassays for insulin-like growth factors and their binding proteins. Growth Regul [Supp 1] 4:11-19
    • (1994) Growth Regul , vol.4 , Issue.1 SUPPL. , pp. 11-19
    • Blum, W.F.1    Breier, B.H.2
  • 19
    • 0027332480 scopus 로고
    • Insulin-like growth factors and their binding proteins in plasma and milk after growth hormone stimulated galactopoiesis in normally lactating women
    • Copenh
    • Breier BH, Milsom SR, Blum WF, Schwander J, Gallaher BW, Gluckman PD 1993 Insulin-like growth factors and their binding proteins in plasma and milk after growth hormone stimulated galactopoiesis in normally lactating women. Acta Endocrinol (Copenh) 129:427-435
    • (1993) Acta Endocrinol , vol.129 , pp. 427-435
    • Breier, B.H.1    Milsom, S.R.2    Blum, W.F.3    Schwander, J.4    Gallaher, B.W.5    Gluckman, P.D.6
  • 20
    • 0019163929 scopus 로고
    • Characterization of a specific receptor for somatomedin C (SM-C) on cultured human lymphocytes: Evidence that SM-C modulates homologous receptor concentration
    • Rosenfeld RG, Hintz RL 1980 Characterization of a specific receptor for somatomedin C (SM-C) on cultured human lymphocytes: evidence that SM-C modulates homologous receptor concentration. Endocrinology 107:1841-1848
    • (1980) Endocrinology , vol.107 , pp. 1841-1848
    • Rosenfeld, R.G.1    Hintz, R.L.2
  • 21
    • 0022658554 scopus 로고
    • Interaction of monoclonal antibodies αIR-1 and αIR-3 with insulin and somatomedin-C receptors
    • Jacobs S, Cook S, Svoboda ME, van Wyk JJ 1986 Interaction of monoclonal antibodies αIR-1 and αIR-3 with insulin and somatomedin-C receptors. Endocrinology 118:223-226
    • (1986) Endocrinology , vol.118 , pp. 223-226
    • Jacobs, S.1    Cook, S.2    Svoboda, M.E.3    Van Wyk, J.J.4
  • 22
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction
    • Cheng YC, Prusoff WH 1973 Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.C.1    Prusoff, W.H.2
  • 23
    • 0023886620 scopus 로고
    • Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells
    • Furlanetto R 1988 Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells. Endocrinology 122:2044-2053
    • (1988) Endocrinology , vol.122 , pp. 2044-2053
    • Furlanetto, R.1
  • 24
    • 0028061877 scopus 로고
    • Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: Endocrine changes and effects on body and organ growth
    • Wolf E, Kramer R, Blum WF, Föll J, Brem G 1994 Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: endocrine changes and effects on body and organ growth. Endocrinology 135:1877-1886
    • (1994) Endocrinology , vol.135 , pp. 1877-1886
    • Wolf, E.1    Kramer, R.2    Blum, W.F.3    Föll, J.4    Brem, G.5
  • 26
  • 28
    • 21144465831 scopus 로고
    • Production of foreign proteins in the mammary glands of transgenic mammals
    • Brem G, Besenfelder U, Hartl P 1993 Production of foreign proteins in the mammary glands of transgenic mammals. Chimica oggi 11:21-25
    • (1993) Chimica Oggi , vol.11 , pp. 21-25
    • Brem, G.1    Besenfelder, U.2    Hartl, P.3
  • 29
    • 0022506241 scopus 로고
    • Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I
    • Clemmons DR, Elgin RG, Han VKM, Casella SJ, D'Ercole AJ, Van Wyk JJ 1986 Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I. J Clin Invest 77:1548-1556
    • (1986) J Clin Invest , vol.77 , pp. 1548-1556
    • Clemmons, D.R.1    Elgin, R.G.2    Han, V.K.M.3    Casella, S.J.4    D'Ercole, A.J.5    Van Wyk, J.J.6
  • 30
    • 0026002202 scopus 로고
    • Insulin-like growth factor (IGF) binding to cell monolayers is directly modulated by the addition of IGF-binding proteins
    • McCusker RH, Busby WH, Dehoff MH, Camacho-Hubner C, Clemmons DR 1991 Insulin-like growth factor (IGF) binding to cell monolayers is directly modulated by the addition of IGF-binding proteins. Endocrinology 129:939-949
    • (1991) Endocrinology , vol.129 , pp. 939-949
    • McCusker, R.H.1    Busby, W.H.2    Dehoff, M.H.3    Camacho-Hubner, C.4    Clemmons, D.R.5
  • 31
    • 0030044883 scopus 로고    scopus 로고
    • Targeted expression of des(1-3) human insulin-like growth factor 1 in transgenic mice influences mammary gland development and IGF-binding protein expression
    • Hadsell DL, Greenberg NM, Fligger JM, Baumrucker CR, Rosen JR 1996 Targeted expression of des(1-3) human insulin-like growth factor 1 in transgenic mice influences mammary gland development and IGF-binding protein expression. Endocrinology 137:321-330
    • (1996) Endocrinology , vol.137 , pp. 321-330
    • Hadsell, D.L.1    Greenberg, N.M.2    Fligger, J.M.3    Baumrucker, C.R.4    Rosen, J.R.5
  • 32
    • 0027502282 scopus 로고
    • Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs
    • Oh Y, Müller HL, Lee DY, Fielder PJ, Rosenfeld RG 1943 Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs. Endocrinology 132:1337-1344
    • (1943) Endocrinology , vol.132 , pp. 1337-1344
    • Oh, Y.1    Müller, H.L.2    Lee, D.Y.3    Fielder, P.J.4    Rosenfeld, R.G.5
  • 33
    • 0024592852 scopus 로고
    • A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1)
    • Carlsson-Skwirut C, Lake M, Hartmanis M, Hall K, Sara VR 1989 A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1). Biochim Biophys Acta 1101:192-197
    • (1989) Biochim Biophys Acta , vol.1101 , pp. 192-197
    • Carlsson-Skwirut, C.1    Lake, M.2    Hartmanis, M.3    Hall, K.4    Sara, V.R.5
  • 34
    • 0025081082 scopus 로고
    • Regulation of binding proteins for insulin-like growth factors (IGF) in humans: Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia
    • Zapf J, Schmid C, Guler HP, Waldvogel M, Hauri C, Futo E, Hossenlopp P, Binoux M, Froesch ER 1990 Regulation of binding proteins for insulin-like growth factors (IGF) in humans: increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia. J Clin Invest 86:952-961
    • (1990) J Clin Invest , vol.86 , pp. 952-961
    • Zapf, J.1    Schmid, C.2    Guler, H.P.3    Waldvogel, M.4    Hauri, C.5    Futo, E.6    Hossenlopp, P.7    Binoux, M.8    Froesch, E.R.9
  • 35
    • 0027385551 scopus 로고
    • Recombinant insulin-like growth factor binding protein-1 inhibits IGF-1, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells
    • Figueroa JA, Sharma J, Jackson JG, McDermott MJ, Hilsenbeck SG, Yee D 1993 Recombinant insulin-like growth factor binding protein-1 inhibits IGF-1, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells. J Cell Physiol 157:229-236
    • (1993) J Cell Physiol , vol.157 , pp. 229-236
    • Figueroa, J.A.1    Sharma, J.2    Jackson, J.G.3    McDermott, M.J.4    Hilsenbeck, S.G.5    Yee, D.6
  • 36
    • 0027199617 scopus 로고
    • Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells: Cell surface binding and growth inhibition
    • Oh Y, Müller HL, Lamson G, Rosenfeld RG 1993 Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells: cell surface binding and growth inhibition. J Biol Chem 268:14964-14971
    • (1993) J Biol Chem , vol.268 , pp. 14964-14971
    • Oh, Y.1    Müller, H.L.2    Lamson, G.3    Rosenfeld, R.G.4
  • 37
    • 0024212837 scopus 로고
    • Maternal and neonatal somato-medin C/insulin-like growth factor-I (IGF-1) and IGF binding proteins during early lactation in the pig
    • Simmen FA, Simmen RC, Reinhart G 1988 Maternal and neonatal somato-medin C/insulin-like growth factor-I (IGF-1) and IGF binding proteins during early lactation in the pig. Dev Biol 130:16-27
    • (1988) Dev Biol , vol.130 , pp. 16-27
    • Simmen, F.A.1    Simmen, R.C.2    Reinhart, G.3
  • 38
    • 0026180777 scopus 로고
    • Insulin-like growth factor (IGF)-I and -II and IGF binding proteins in serum and mammary secretions during the dry period and early lactation in dairy cows
    • Vega JR, Gibson CA, Skaar TC, Hadsell DL, Baumrucker CR 1991 Insulin-like growth factor (IGF)-I and -II and IGF binding proteins in serum and mammary secretions during the dry period and early lactation in dairy cows. J Anim Sci 69:2538-2547
    • (1991) J Anim Sci , vol.69 , pp. 2538-2547
    • Vega, J.R.1    Gibson, C.A.2    Skaar, T.C.3    Hadsell, D.L.4    Baumrucker, C.R.5
  • 39
    • 0025967249 scopus 로고
    • Insulin-like growth factors I and II and their binding proteins in rat milk
    • Donovan SM, Hintz RL, Wilson DM, Rosenfeld RG 1991 Insulin-like growth factors I and II and their binding proteins in rat milk. Pediatr Res 29:50-55
    • (1991) Pediatr Res , vol.29 , pp. 50-55
    • Donovan, S.M.1    Hintz, R.L.2    Wilson, D.M.3    Rosenfeld, R.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.