Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays

Molecular Diversity

Volumn 4, Issue 2, 1998, Pages 91-102

  Appel, Jon R ^a   Johnson, Jill ^b   Narayanan, Ven L ^b   Houghten, Richard A ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antitumor agents; Cancer drug discovery; Combinatorial chemistry; High throughput screening; Mixtures; Positional scanning; Synthetic combinatorial libraries

Indexed keywords

ANTINEOPLASTIC AGENT;

ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; FACTUAL DATABASE; HEALTH CARE ORGANIZATION; HUMAN; MOUSE; SYNTHESIS; UNITED STATES;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DATABASES, FACTUAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; NATIONAL INSTITUTES OF HEALTH (U.S.); TUMOR CELLS, CULTURED; UNITED STATES;

EID: 0032234338     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026441400053     Document Type: Article

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