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Volumn 152, Issue 2, 1998, Pages 376-387

In vitro to in vivo extrapolation for trichloroethylene metabolism in humans

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAL HYDRATE; CYTOCHROME P450; GLUCOSE 6 PHOSPHATASE; TRICHLOROETHYLENE;

EID: 0032191413     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8485     Document Type: Article
Times cited : (77)

References (52)
  • 1
    • 0030694692 scopus 로고    scopus 로고
    • A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol and trichloroethanol glucuronide in B6C3F1 mice
    • Abbas R., Fisher J. W. A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol and trichloroethanol glucuronide in B6C3F1 mice. Toxicol. Appl. Pharmacol. 147:1997;15-30.
    • (1997) Toxicol. Appl. Pharmacol. , vol.147 , pp. 15-30
    • Abbas, R.1    Fisher, J.W.2
  • 2
    • 0030453962 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice
    • Abbas R. R., Seckel C. S., Kidney J. K., Fisher J. W. Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice. Drug Metab. Dispos. 24:1996;1340-1346.
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 1340-1346
    • Abbas, R.R.1    Seckel, C.S.2    Kidney, J.K.3    Fisher, J.W.4
  • 3
    • 0027535473 scopus 로고
    • Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans
    • Allen B. C., Fisher J. W. Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans. Risk Anal. 13:1993;71-85.
    • (1993) Risk Anal. , vol.13 , pp. 71-85
    • Allen, B.C.1    Fisher, J.W.2
  • 6
    • 0030036369 scopus 로고    scopus 로고
    • Evaluating human variability in chemical risk assessment: Hazard identification and dose-response assessment for noncancer oral toxicity of trichloroethylene
    • Barton H. A., Flemming C. D., Lipscomb J. C. Evaluating human variability in chemical risk assessment: Hazard identification and dose-response assessment for noncancer oral toxicity of trichloroethylene. Toxicology. 110:1996;271-287.
    • (1996) Toxicology , vol.110 , pp. 271-287
    • Barton, H.A.1    Flemming, C.D.2    Lipscomb, J.C.3
  • 7
    • 0017609420 scopus 로고
    • The metabolism of drugs in isolated hepatocytes: A comparison within vivo
    • Billings R. E., McMahon R. E., Ashmore J., Wagle S. R. The metabolism of drugs in isolated hepatocytes: A comparison within vivo. Drug Metab. Dispos. 5:1977;518-526.
    • (1977) Drug Metab. Dispos. , vol.5 , pp. 518-526
    • Billings, R.E.1    McMahon, R.E.2    Ashmore, J.3    Wagle, S.R.4
  • 8
    • 0030850023 scopus 로고    scopus 로고
    • Scaling factors to relate metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: Studies with induced livers involving diazepam
    • Carlile D. J., Zomorodi K., Houston J. B. Scaling factors to relate metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: Studies with induced livers involving diazepam. Drug Metab. Dispos. 25:1997;903-911.
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 903-911
    • Carlile, D.J.1    Zomorodi, K.2    Houston, J.B.3
  • 9
    • 0015959243 scopus 로고
    • Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism
    • Carlson G. P. Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism. Res. Comm. Chem. Pathol. Pharmacol. 7:1974;637-640.
    • (1974) Res. Comm. Chem. Pathol. Pharmacol. , vol.7 , pp. 637-640
    • Carlson, G.P.1
  • 11
    • 77957179532 scopus 로고
    • Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse
    • Daniel F. B., DeAngelo A. B., Stober J. A., Olson G. R., Page N. R. Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse. Fundam. Appl. Toxicol. 19:1992;159-168.
    • (1992) Fundam. Appl. Toxicol. , vol.19 , pp. 159-168
    • Daniel, F.B.1    Deangelo, A.B.2    Stober, J.A.3    Olson, G.R.4    Page, N.R.5
  • 14
    • 0027994150 scopus 로고
    • A new technique for isolating and culturing human hepatocytes from whole or split livers not used for transplantation
    • Dorko K., Freeswick P. D., Bartoli F., Cicalese L., Bardsley B. A., Tzakis A., Nussler A. K. A new technique for isolating and culturing human hepatocytes from whole or split livers not used for transplantation. Cell Transplant. 3:1994;387-395.
    • (1994) Cell Transplant. , vol.3 , pp. 387-395
    • Dorko, K.1    Freeswick, P.D.2    Bartoli, F.3    Cicalese, L.4    Bardsley, B.A.5    Tzakis, A.6    Nussler, A.K.7
  • 15
    • 0030297476 scopus 로고    scopus 로고
    • Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 rats
    • el Masri H. A., Constan A. A., Ramsdell H. S., Yang R. S. Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 rats. Toxicol. Appl. Pharmacol. 121:1996;124-132.
    • (1996) Toxicol. Appl. Pharmacol. , vol.121 , pp. 124-132
    • El Masri, H.A.1    Constan, A.A.2    Ramsdell, H.S.3    Yang, R.S.4
  • 16
    • 0000593892 scopus 로고
    • Sensitivity analysis and the design of gas uptake inhalation studies
    • Evans M. V., Andersen M. E. Sensitivity analysis and the design of gas uptake inhalation studies. Inhalation Toxicol. 7:1995;1075-1094.
    • (1995) Inhalation Toxicol. , vol.7 , pp. 1075-1094
    • Evans, M.V.1    Andersen, M.E.2
  • 17
    • 0025826666 scopus 로고
    • Physiologically based pharmacokinetic modeling with trichloroethylene and its metabolite, trichloroacetic acid, in the rat and mouse
    • Fisher J. W., Gargas M. L., Allen B. C., Andersen M. E. Physiologically based pharmacokinetic modeling with trichloroethylene and its metabolite, trichloroacetic acid, in the rat and mouse. Toxicol. Appl. Pharmacol. 109:1991;183-195.
    • (1991) Toxicol. Appl. Pharmacol. , vol.109 , pp. 183-195
    • Fisher, J.W.1    Gargas, M.L.2    Allen, B.C.3    Andersen, M.E.4
  • 18
    • 0032192157 scopus 로고    scopus 로고
    • A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol
    • Fisher J. W., Mahle D. A., Abbas R. A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol. Toxicol. Appl. Pharmacol. 1998.
    • (1998) Toxicol. Appl. Pharmacol.
    • Fisher, J.W.1    Mahle, D.A.2    Abbas, R.3
  • 19
    • 0000428146 scopus 로고
    • Analysis and characterization of enzymes
    • A.W. Hayes. New York: Raven Press
    • Guengerich F. P. Analysis and characterization of enzymes. Hayes A. W. Principles and Methods of Toxicology. 1989;777-814 Raven Press, New York.
    • (1989) Principles and Methods of Toxicology , pp. 777-814
    • Guengerich, F.P.1
  • 20
    • 0026035519 scopus 로고
    • Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich F. P., Kim D. H., Iwasaki M. Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4:1991;168-179.
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.H.2    Iwasaki, M.3
  • 21
    • 0023510171 scopus 로고
    • The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver
    • Herren-Freund S. L., Periera M. A., Khoury M. D., Olson G. The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver. Toxicol. Appl. Pharmacol. 90:1987;183-189.
    • (1987) Toxicol. Appl. Pharmacol. , vol.90 , pp. 183-189
    • Herren-Freund, S.L.1    Periera, M.A.2    Khoury, M.D.3    Olson, G.4
  • 22
    • 0028342648 scopus 로고
    • Utility of in vitro drug metabolism data in predictingin vivo
    • Houston J. B. Utility of in vitro drug metabolism data in predictingin vivo. Biochem. Pharmacol. 47:1994;1469-1479.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1469-1479
    • Houston, J.B.1
  • 23
    • 0344333422 scopus 로고    scopus 로고
    • Prediction of hepatic clearance from microsomes, hepatocytes and liver slices
    • Houston J. B., Carlile D. J. Prediction of hepatic clearance from microsomes, hepatocytes and liver slices. Drug Metab. Rev. 29:1997;891-922.
    • (1997) Drug Metab. Rev. , vol.29 , pp. 891-922
    • Houston, J.B.1    Carlile, D.J.2
  • 27
    • 0030246901 scopus 로고    scopus 로고
    • Prediction of furan pharmacokinetics from hepatocyte studies: Comparison of bioactivation and hepatocyte dosimetry in rats, mice and humans
    • Kedderis G. L., Held S. D. Prediction of furan pharmacokinetics from hepatocyte studies: Comparison of bioactivation and hepatocyte dosimetry in rats, mice and humans. Toxicol. Appl. Pharmacol. 140:1996;124-130.
    • (1996) Toxicol. Appl. Pharmacol. , vol.140 , pp. 124-130
    • Kedderis, G.L.1    Held, S.D.2
  • 29
    • 0026684304 scopus 로고
    • Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice
    • Larson J. L., Bull R. J. Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice. Toxicol. Appl. Pharmacol. 115:1992;268-277.
    • (1992) Toxicol. Appl. Pharmacol. , vol.115 , pp. 268-277
    • Larson, J.L.1    Bull, R.J.2
  • 30
    • 0013814496 scopus 로고
    • Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate
    • Leibman K. H. Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate. Mol. Pharmacol. 1:1965;239-246.
    • (1965) Mol. Pharmacol. , vol.1 , pp. 239-246
    • Leibman, K.H.1
  • 32
    • 0018962319 scopus 로고
    • Kinetic studies on the dethylation of ethoxybenzamide: A comparative study with isolated hepatocytes and liver microsomes of rat
    • Lin J. H., Sugiyama Y., Awazu S., Hanano M. Kinetic studies on the dethylation of ethoxybenzamide: A comparative study with isolated hepatocytes and liver microsomes of rat. Biochem. Pharmacol. 29:1980;2825-2830.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 2825-2830
    • Lin, J.H.1    Sugiyama, Y.2    Awazu, S.3    Hanano, M.4
  • 33
    • 0020279521 scopus 로고
    • Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtainedin vitro
    • Lin J. H., Sugiyama Y., Awazu S., Hanano M. Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtainedin vitro. J. Pharmacokinet. Biopharm. 10:1982;649-661.
    • (1982) J. Pharmacokinet. Biopharm. , vol.10 , pp. 649-661
    • Lin, J.H.1    Sugiyama, Y.2    Awazu, S.3    Hanano, M.4
  • 34
    • 0031062286 scopus 로고    scopus 로고
    • Cytochrome P450 dependent metabolism of trichloroethylene: Interindividual differences in humans
    • Lipscomb J. C., Garrett C. M., Snawder J. E. Cytochrome P450 dependent metabolism of trichloroethylene: Interindividual differences in humans. Toxicol. Appl. Pharmacol. 142:1997;311-318.
    • (1997) Toxicol. Appl. Pharmacol. , vol.142 , pp. 311-318
    • Lipscomb, J.C.1    Garrett, C.M.2    Snawder, J.E.3
  • 35
    • 2642709830 scopus 로고    scopus 로고
    • Use of kinetic and mechanistic data in species extrapolation of bioactivation: Cytochrome P-450 dependent trichloroethylene metabolism at occupationally relevant concentrations
    • Lipscomb J. C., Garrett C. M., Snawder J. E. Use of kinetic and mechanistic data in species extrapolation of bioactivation: Cytochrome P-450 dependent trichloroethylene metabolism at occupationally relevant concentrations. J. Occup. Health. 40:1998;110-117.
    • (1998) J. Occup. Health , vol.40 , pp. 110-117
    • Lipscomb, J.C.1    Garrett, C.M.2    Snawder, J.E.3
  • 36
    • 0018950417 scopus 로고
    • Gas chromatographic method for the halothane metabolites, trifluoroacetic acid and bromide, in biological fluids
    • Maiorino R. M., Gandolfi A. J., Sipes I. G. Gas chromatographic method for the halothane metabolites, trifluoroacetic acid and bromide, in biological fluids. Anal. Tox. 4:1980;250-254.
    • (1980) Anal. Tox. , vol.4 , pp. 250-254
    • Maiorino, R.M.1    Gandolfi, A.J.2    Sipes, I.G.3
  • 37
    • 0025106144 scopus 로고
    • Drug metabolizing capacityin vitroin vivo.
    • Matthew D. E., Houston J. B. Drug metabolizing capacityin vitroin vivo. Biochem. Pharmacol. 40:1990a;743-749.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 743-749
    • Matthew, D.E.1    Houston, J.B.2
  • 38
    • 0025032055 scopus 로고
    • Drug metabolizing capacityin vitroin vivo.
    • Matthew D. E., Houston J. B. Drug metabolizing capacityin vitroin vivo. Biochem. Pharmacol. 40:1990b;751-758.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 751-758
    • Matthew, D.E.1    Houston, J.B.2
  • 40
    • 0016284292 scopus 로고
    • Metabolism of trichloroethylene in man. II Pharmacokinetics of the metabolites
    • Muller G., Spassovski M., Henschler D. Metabolism of trichloroethylene in man. II Pharmacokinetics of the metabolites. Arch. Toxicol. 32:1974;283-295.
    • (1974) Arch. Toxicol. , vol.32 , pp. 283-295
    • Muller, G.1    Spassovski, M.2    Henschler, D.3
  • 41
    • 0016806538 scopus 로고
    • Metabolism of trichloroethylene in man. III Interaction of trichloroethylene and ethanol
    • Muller G., Spassovski M., Henschler D. Metabolism of trichloroethylene in man. III Interaction of trichloroethylene and ethanol. Arch. Toxicol. 33:1975;173-189.
    • (1975) Arch. Toxicol. , vol.33 , pp. 173-189
    • Muller, G.1    Spassovski, M.2    Henschler, D.3
  • 42
    • 0023719057 scopus 로고
    • Ethanol-induced enhancement of trichloroethylene metabolism and hepatotoxicity: Difference from the effect of phenobarbital
    • Nakajima T., Okino T., Okuyama S., Kaneko T., Yonekura I., Sato A. Ethanol-induced enhancement of trichloroethylene metabolism and hepatotoxicity: Difference from the effect of phenobarbital. Toxicol. Appl. Pharmacol. 94:1988;227-237.
    • (1988) Toxicol. Appl. Pharmacol. , vol.94 , pp. 227-237
    • Nakajima, T.1    Okino, T.2    Okuyama, S.3    Kaneko, T.4    Yonekura, I.5    Sato, A.6
  • 43
    • 78651165715 scopus 로고
    • The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T., Sato R. The carbon monoxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239:1964;2370-2378.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 44
    • 0024351276 scopus 로고
    • Intra- and interindividual variability in the kinetics of a poorly and highly metabolizing solvent
    • Opdam J. J. G. Intra- and interindividual variability in the kinetics of a poorly and highly metabolizing solvent. Br. J. Ind. Med. 46:1989;831-845.
    • (1989) Br. J. Ind. Med. , vol.46 , pp. 831-845
    • Opdam, J.J.G.1
  • 48
    • 0018350651 scopus 로고
    • A vial-equilibration method to evaluate the drug-metabolizing enzyme activity for volatile hydrocarbons
    • Sato A., Nakajima T. A vial-equilibration method to evaluate the drug-metabolizing enzyme activity for volatile hydrocarbons. Toxicol. Appl. Pharmacol. 47:1979;41-46.
    • (1979) Toxicol. Appl. Pharmacol. , vol.47 , pp. 41-46
    • Sato, A.1    Nakajima, T.2
  • 49
    • 0015752890 scopus 로고
    • Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion
    • Seglan P. O. Preparation of rat liver cells. III. Enzymatic requirements for tissue dispersion. Exp. Cell. Res. 82:1973;391-398.
    • (1973) Exp. Cell. Res. , vol.82 , pp. 391-398
    • Seglan, P.O.1
  • 50
    • 0031468634 scopus 로고    scopus 로고
    • Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene
    • Simon T. W. Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene. Regul. Toxicol. Pharmacol. 26:1997;257-270.
    • (1997) Regul. Toxicol. Pharmacol. , vol.26 , pp. 257-270
    • Simon, T.W.1
  • 51
    • 0018755319 scopus 로고
    • N-Demethylation of aminopyrinein vivo
    • Stewart D. J., Inaba T. N-Demethylation of aminopyrinein vivo. Biochem. Pharmacol. 28:1979;461-464.
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 461-464
    • Stewart, D.J.1    Inaba, T.2


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