Scaling factors to relate drug metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: Studies with induced livers involving diazepam

Drug Metabolism and Disposition

Volumn 25, Issue 8, 1997, Pages 903-911

  Carlile, David J ^c   Zomorodi, Katayoun ^a   Houston, J Brian ^b  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DEXAMETHASONE; DIAZEPAM; PHENOBARBITAL;

ARTICLE; CELL ISOLATION; DRUG METABOLISM; HYDROXYLATION; LIVER CELL; LIVER MICROSOME; METABOLIC CLEARANCE RATE; PREDICTION; PRIORITY JOURNAL;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DIAZEPAM; LIVER; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030850023     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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