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Lee ER, Marshall J, Siegel CS, Jiang C, Yew NS, Nichols MR, Nietupski JB, Ziegler RJ, Lane MB, Wang KX. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Hum Gene Ther. 7:1996;1701-1717.
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Synthesis, activity, and structure-activity relationship studies of novel cationic lipids for DNA transfer
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Byk G, Dubertret C, Escriou V, Frederic M, Jaslin G, Rangara R, Pitard B, Crouzet J, Wils P, Schwartz B, Scherman D. Synthesis, activity, and structure-activity relationship studies of novel cationic lipids for DNA transfer. J Med Chem. 41:1998;224-235.
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Scherman, D.11
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0031561102
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A cationic lipid for rapid and efficient delivery of plasmid DNA into mammalian cells
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Zhang G, Gurtu V, Smith TH, Nelson P, Kain SR. A cationic lipid for rapid and efficient delivery of plasmid DNA into mammalian cells. Biochem Biophys Res Commun. 236:1997;126-129.
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Zhang, G.1
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Okayama R, Noji M, Nakanishi M. Cationic cholesterol with a hydroxyethylamino head group promotes significantly liposome-mediated gene transfection. FEBS Lett. 408:1997;232-234.
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Okayama, R.1
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0031041965
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Legendre JY, Trzeciak A, Bohrmann B, Deuschle U, Kitas E, Supersaxo A. Dioleoylmelittin as a novel serum-insensitive reagent for efficient transfection of mammalian cells. Bioconjug Chem. 8:1997;57-63.
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of special interest. A membrane disruption agent, dodecyl-2-(imidazolyl)propionate (DIP), was incorporated in a delivery vector and showed enhancement of transgene expression by fivefold in vitro by selectively increasing the release of endosomally encapsulated DNA.
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Liang E, Hughes J. Characterization of a pH-sensitive surfactant, dodecyl-2-(1'-imidazolyl) propionate (DIP), and preliminary studies in liposome mediated gene transfer. of special interest Biochim Biophys Acta. 1369:1998;39-50 A membrane disruption agent, dodecyl-2-(imidazolyl)propionate (DIP), was incorporated in a delivery vector and showed enhancement of transgene expression by fivefold in vitro by selectively increasing the release of endosomally encapsulated DNA.
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Liang, E.1
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Probing DNA-cationic lipid interactions with the fluorophore trimethylammonium diphenylhexatriene (TMADPH)
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Hirsch-Lerner D, Barenholz Y. Probing DNA-cationic lipid interactions with the fluorophore trimethylammonium diphenylhexatriene (TMADPH). Biochim Biophys Acta. 1370:1998;17-30.
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14
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of outstanding interest. To investigate the possibility of studying a DNA transfection event by contrast NMR, a gadolinium-chelated liposomal contrast agent was prepared. DNA transfection in vitro confirmed the activity of the contrast agent and exemplified the potential of this system for developing new imaging and DNA delivery vehicles.
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Wisner ER, Aho-Sharon KL, Bennett MJ, Penn SG, Lebrilla CB, Nantz MH. A modular lymphographic magnetic resonance imaging contrast agent: contrast enhancement with DNA transfection potential. of outstanding interest J Med Chem. 40:1997;3992-3996 To investigate the possibility of studying a DNA transfection event by contrast NMR, a gadolinium-chelated liposomal contrast agent was prepared. DNA transfection in vitro confirmed the activity of the contrast agent and exemplified the potential of this system for developing new imaging and DNA delivery vehicles.
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Wisner, E.R.1
Aho-Sharon, K.L.2
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Lebrilla, C.B.5
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Blessing T, Rémy JS, Behr JP. Molecular collapse of plasmid DNA into stable virus-like particles. Proc Natl Acad Sci USA. 95:1998;1427-1431.
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Blessing, T.1
Rémy, J.S.2
Behr, J.P.3
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Anchordoquy J, Carpenter JF, Kroll DJ. Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration. Arch Biochem Biophys. 348:1997;199-206.
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Carpenter, J.F.2
Kroll, D.J.3
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19
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of outstanding interest. This paper shows that DNA associated with unilamellar liposomes of DOTAP/DOPC form multilamellar vesicles containing the DNA molecules intercalated between the lipid bilayers.
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Radler, J.O.1
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Virus-sized self-assembling lamellar complexes between plasmid DNA and cationic micelles promote gene transfer
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Pitard B, Aguerre O, Airiau M, Lachagès AM, Boukhnikachvili T, Byk G, Dubertret C, Herviou C, Scherman D, Mayaux JF, Crouzet J. Virus-sized self-assembling lamellar complexes between plasmid DNA and cationic micelles promote gene transfer. Proc Natl Acad Sci USA. 94:1997;14412-14417.
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Pitard, B.1
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Dubertret, C.7
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Scherman, D.9
Mayaux, J.F.10
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Matsui H, Johnson LG, Randell SH, Boucher RC. Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. J Biol Chem. 272:1997;1117-1126.
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Vandenbranden, M.6
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25
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Escriou V, Ciolina C, Lacroix F, Byk G, Scherman D, Wils P. Cationic lipid-mediated gene transfer: effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes. Biochim Biophys Acta. 1368:1998;276-288.
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0030876816
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Analysis of cationic liposome-mediated interactions of plasmid DNA with murine and human melanoma cells in vitro
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Reimer DL, Kong S, Bally MB. Analysis of cationic liposome-mediated interactions of plasmid DNA with murine and human melanoma cells in vitro. J Biol Chem. 272:1997;19480-19487.
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Reimer, D.L.1
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Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression
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of special interest. This paper gives a detailed quantitative analysis of intracellular DNA delivery and transgene expression at the single cell level. The results show that plasmid delivery heterogeneity in a cell population is responsible for transfection heterogeneity.
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Tseng WC, Haselton FR, Giorgio TD. Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. of special interest J Biol Chem. 272:1997;25641-25647 This paper gives a detailed quantitative analysis of intracellular DNA delivery and transgene expression at the single cell level. The results show that plasmid delivery heterogeneity in a cell population is responsible for transfection heterogeneity.
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Tseng, W.C.1
Haselton, F.R.2
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Stegman T, Legendre JY. Gene transfer mediated by cationic lipids: lack of correlation between lipid mixing and transfection. Biochim Biophys Acta. 1325:1997;71-79.
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Stegman, T.1
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Pollard H, Remy JS, Loussouarn G, Demolomble S, Behr JP, Escande D. Polyethylenimine but not cationic lipids promote transgene delivery to the nucleus in mammalian cells. J Biol Chem. 273:1998;7507-7511.
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31
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An electron microscopy study into the mechanism to gene transfer with lipopolyamines
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Labat-Moleur F, Steffan AM, Brisson C, Perron H, Feugeas O, Furstenberger P, Oberling F, Brambilla E, Behr JP. An electron microscopy study into the mechanism to gene transfer with lipopolyamines. Gene Ther. 3:1996;1010-1017.
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Wagner JA, Gardner P. Toward cystic fibrosis gene therapy. Annu Rev Med. 48:1997;203-216.
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Knowles MR, Noone PG, Hohneker K, Johnson LG, Boucher RC, Efthimiou J, Crawford C, Brown R, Schwartzbach C, Pearlman R. A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis. Hum Gene Ther. 9:1998;249-269.
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Oudrhiri N, Vigneron JP, Peuchmaur M, Leclerc T, Lehn JM, Lehn P. Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo. Proc Natl Acad Sci USA. 94:1997;1651-1656.
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36
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8244224532
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Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7
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Rubin J, Galanis E, Pitot HC, Richardson RL, Burch PA, Charboneau JW, Reading CC, Lewis BD, Stahl S, Akporiaye ET, Harris DT. Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7. Gene Ther. 4:1997;419-425.
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Hui KM, Ang PT, Huang L, Tay SK. Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Ther. 4:1997;783-790.
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Zlokovic BV, Apuzzo ML. Cellular and molecular neurosurgery: pathways from concept to reality - part II: vector systems and delivery methodologies for gene therapy of the central nervous system. Neurosurgery. 40:1997;805-812.
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Okamoto T, Kaneda Y, Yuzuki D, Huang SK, Chi DD, Hoon DS. Induction of antibody response to human tumor antigens by gene therapy using a fusigenic viral liposome vaccine. Gene Ther. 4:1997;969-976.
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