메뉴 건너뛰기




Volumn 27, Issue 2-3, 1998, Pages 129-140

Intracellular cytokine expression in the CD4+ and CD8+ T cells from intestinal mucosa of simian immunodeficiency virus infected macaques

Author keywords

AIDS; Enteropathy; HIV; IEL; IFN ; IL 10; Intracellular flow cytometry; LPL; Nonhuman primates; SIV

Indexed keywords

ANIMALIA; MACACA; PRIMATES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0032036787     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0684.1998.tb00237.x     Document Type: Article
Times cited : (14)

References (76)
  • 1
    • 0009519778 scopus 로고    scopus 로고
    • Lamina propria lymphocytes: A unique population of mucosal lymphocytes
    • Kagnoff MF and Kiyono H (eds). Academic Press, Inc., London
    • ABREU-MARTIN MT, TARGAN SR: Lamina propria lymphocytes: a unique population of mucosal lymphocytes. In: Essentials of Mucosal Immunology. Kagnoff MF and Kiyono H (eds). Academic Press, Inc., London, pp 227-245, 1996.
    • (1996) Essentials of Mucosal Immunology , pp. 227-245
    • Abreu-Martin, M.T.1    Targan, S.R.2
  • 2
    • 0027245531 scopus 로고
    • IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding
    • ADAMS RB, PLANCHON SM, ROCHE JK: IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding. J Immunol 150:2356-2363, 1993.
    • (1993) J Immunol , vol.150 , pp. 2356-2363
    • Adams, R.B.1    Planchon, S.M.2    Roche, J.K.3
  • 3
    • 0028232637 scopus 로고
    • Th1 and Th2 cytokine production by peripheral blood mononuclear cells from HIV-infected patients
    • BARCELLINI W, RIZZARDI GP, BORGHI MO, FAIN C, LAZZARIN A, MERONI PL: Th1 and Th2 cytokine production by peripheral blood mononuclear cells from HIV-infected patients. AIDS 8:757, 1994.
    • (1994) AIDS , vol.8 , pp. 757
    • Barcellini, W.1    Rizzardi, G.P.2    Borghi, M.O.3    Fain, C.4    Lazzarin, A.5    Meroni, P.L.6
  • 5
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial γδT cells
    • BOISMENU R, HAVRAN WL: Modulation of epithelial cell growth by intraepithelial γδT cells. Science 266:1253, 1994.
    • (1994) Science , vol.266 , pp. 1253
    • Boismenu, R.1    Havran, W.L.2
  • 6
    • 0027441514 scopus 로고
    • Interleukin-2 and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa
    • BREESE E, BRAEGGER CP, CORRIGAN CJ, WALKER-SMITH JA, MACDONALD TT: Interleukin-2 and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa. Immunology 78:127-131, 1993.
    • (1993) Immunology , vol.78 , pp. 127-131
    • Breese, E.1    Braegger, C.P.2    Corrigan, C.J.3    Walker-Smith, J.A.4    Macdonald, T.T.5
  • 8
    • 0017646342 scopus 로고
    • Isolation and functional characterization of human intestinal mucosal lymphoid cells
    • BULL DM, BOOKMAN MA: Isolation and functional characterization of human intestinal mucosal lymphoid cells. J Clin Invest 59:966-974, 1977.
    • (1977) J Clin Invest , vol.59 , pp. 966-974
    • Bull, D.M.1    Bookman, M.A.2
  • 9
    • 0028172540 scopus 로고
    • Toxoplasma gondii oral infection induces specific cytotoxic CD3 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes
    • CHARDES T, BUZONI-GATEL D, LEPAGE A, BERNARD F, BOUT D: Toxoplasma gondii oral infection induces specific cytotoxic CD3 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes. Journal of Immunology 153:4596-4603, 1994.
    • (1994) Journal of Immunology , vol.153 , pp. 4596-4603
    • Chardes, T.1    Buzoni-Gatel, D.2    Lepage, A.3    Bernard, F.4    Bout, D.5
  • 11
    • 0027340164 scopus 로고
    • A TH1→TH2 switch is a critical step in the etiology of HIV infection
    • CLERICI M, SHEARER GM: A TH1→TH2 switch is a critical step in the etiology of HIV infection. Immunol Today 14:107-111, 1993.
    • (1993) Immunol Today , vol.14 , pp. 107-111
    • Clerici, M.1    Shearer, G.M.2
  • 12
    • 43949158538 scopus 로고
    • The Th1-Th2 hypothesis of HIV infection: New insights
    • CLERICI M, SHEARER GM: The Th1-Th2 hypothesis of HIV infection: New insights. Immunol Today 15:575-581, 1994.
    • (1994) Immunol Today , vol.15 , pp. 575-581
    • Clerici, M.1    Shearer, G.M.2
  • 13
    • 1842292203 scopus 로고    scopus 로고
    • Direct ex vivo simian immunodeficiency virus (SIV)-specific cytotoxic activity detected from small intestine intraepithelial lymphocytes of SIV-infected macaques at an advanced stage of infection
    • COUEDEL-COURTEILLE A, LE GRAND R, TULLIEZ M, GUILLET JG, VENET A: Direct ex vivo simian immunodeficiency virus (SIV)-specific cytotoxic activity detected from small intestine intraepithelial lymphocytes of SIV-infected macaques at an advanced stage of infection. J Virol 71:1052-1057, 1997.
    • (1997) J Virol , vol.71 , pp. 1052-1057
    • Couedel-Courteille, A.1    Le Grand, R.2    Tulliez, M.3    Guillet, J.G.4    Venet, A.5
  • 14
    • 0019479358 scopus 로고
    • Preparation and purification of lymphocytes from the epithelium and lamina propria of murine small intestine
    • DAVIES MDJ, PARROTT DVM: Preparation and purification of lymphocytes from the epithelium and lamina propria of murine small intestine. Gut 22:481-488, 1981.
    • (1981) Gut , vol.22 , pp. 481-488
    • Davies, M.D.J.1    Parrott, D.V.M.2
  • 15
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocyts: An autoregulatory role of IL-10 produced by monocytes
    • DE WAAL MALEFYT R, ABRAMS J, BENNETT B, FIGDOR CG, DE VRIES JE: Interleukin 10(IL-10) inhibits cytokine synthesis by human monocyts: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174:1209-1220, 1991.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 16
    • 0025976165 scopus 로고
    • Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells
    • DEEM RL, SHANAHAN F, TARGAN SR: Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells. Clin Exp Immunol 83:79-84, 1991.
    • (1991) Clin Exp Immunol , vol.83 , pp. 79-84
    • Deem, R.L.1    Shanahan, F.2    Targan, S.R.3
  • 17
    • 0026722286 scopus 로고
    • D-xylose malabsorption: Characteristic finding in patients with the AIDS wasting syndrome and chornic diarrhea
    • EHRENPREIS ED, GANGER DR, KOCHVAR GT, PATTERSON BK, CRAIG RM: D-xylose malabsorption: characteristic finding in patients with the AIDS wasting syndrome and chornic diarrhea. J Acquir Immune Defic Syndr 5:1047-1050, 1992.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 1047-1050
    • Ehrenpreis, E.D.1    Ganger, D.R.2    Kochvar, G.T.3    Patterson, B.K.4    Craig, R.M.5
  • 19
    • 0028980812 scopus 로고
    • Differential production of interferongamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo
    • FERRICK DA, SCHRENZEL MD, MULVANIA T, HSIEH B, FERLIN WG, LEPPER H: Differential production of interferongamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo. Nature 373:255-257, 1995.
    • (1995) Nature , vol.373 , pp. 255-257
    • Ferrick, D.A.1    Schrenzel, M.D.2    Mulvania, T.3    Hsieh, B.4    Ferlin, W.G.5    Lepper, H.6
  • 21
    • 0024545655 scopus 로고
    • Detection of HIV-1 RNA in the lamina propria of patients with AIDS and gastrointestinal disease
    • Fox CH, KOTLER D, TIERNEY A, WILSON CS, FAUCI AS: Detection of HIV-1 RNA in the lamina propria of patients with AIDS and gastrointestinal disease. J Infect Dis 159:467-471, 1989.
    • (1989) J Infect Dis , vol.159 , pp. 467-471
    • Fox, C.H.1    Kotler, D.2    Tierney, A.3    Wilson, C.S.4    Fauci, A.S.5
  • 22
    • 0026501181 scopus 로고
    • CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice
    • GAZZINELLI RT, MAKINO M, CHATTOPADHYAY SK, SNAPPER CM, SHER A, HUGIN AW, MORSE HCD: CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice. J Immunol 148:182-188, 1992.
    • (1992) J Immunol , vol.148 , pp. 182-188
    • Gazzinelli, R.T.1    Makino, M.2    Chattopadhyay, S.K.3    Snapper, C.M.4    Sher, A.5    Hugin, A.W.6    Morse, H.C.D.7
  • 24
    • 0028575383 scopus 로고
    • Comparative analysis of constitutive cytokine expression in peripheral blood and lymph nodes of HIV-infected individuals
    • GRAZIOSI C, PANTALEO G, FAUCI AS: Comparative analysis of constitutive cytokine expression in peripheral blood and lymph nodes of HIV-infected individuals. Res Immunol 145:602-607, 1994.
    • (1994) Res Immunol , vol.145 , pp. 602-607
    • Graziosi, C.1    Pantaleo, G.2    Fauci, A.S.3
  • 26
    • 0026101507 scopus 로고
    • AIDS enteropathy: Occult enteric infections and duodenal mucosal alterations in chronic diarrhea
    • GREENSON JK, BELITSOS PC, YARDLEY JH, BARTLETT JG: AIDS enteropathy: occult enteric infections and duodenal mucosal alterations in chronic diarrhea. Ann Intern Med 114:366-372, 1991.
    • (1991) Ann Intern Med , vol.114 , pp. 366-372
    • Greenson, J.K.1    Belitsos, P.C.2    Yardley, J.H.3    Bartlett, J.G.4
  • 27
    • 0025911278 scopus 로고
    • Human immunodeficiency virus infection of enterocytes and mononuclear cells in human jejunal mucosa
    • HEISE C, DANDEKAR S, KUMAR P, DUPLANTIER R, DONOVAN RM, HALSTED CH: Human immunodeficiency virus infection of enterocytes and mononuclear cells in human jejunal mucosa. Gastroenterology 100:1521-1527, 1991.
    • (1991) Gastroenterology , vol.100 , pp. 1521-1527
    • Heise, C.1    Dandekar, S.2    Kumar, P.3    Duplantier, R.4    Donovan, R.M.5    Halsted, C.H.6
  • 28
    • 0028100635 scopus 로고
    • Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction
    • HEISE C, MILLER CJ, LACKNER A, DANDEKAR S: Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction. J Infect Dis 169:1116-1120, 1994.
    • (1994) J Infect Dis , vol.169 , pp. 1116-1120
    • Heise, C.1    Miller, C.J.2    Lackner, A.3    Dandekar, S.4
  • 29
    • 0027755134 scopus 로고
    • Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes
    • HEISE C, VOGEL P, MILLER CJ, HALSTED CH, DANDEKAR S: Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes. Am J Pathol 142:1759-1771, 1993.
    • (1993) Am J Pathol , vol.142 , pp. 1759-1771
    • Heise, C.1    Vogel, P.2    Miller, C.J.3    Halsted, C.H.4    Dandekar, S.5
  • 30
    • 0027549618 scopus 로고
    • Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS
    • HEISE C, VOGEL P, MILLER CJ, LACKNER A, DANDEKAR S: Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS. J Med Primatol 22:187-193, 1993.
    • (1993) J Med Primatol , vol.22 , pp. 187-193
    • Heise, C.1    Vogel, P.2    Miller, C.J.3    Lackner, A.4    Dandekar, S.5
  • 31
    • 0025600961 scopus 로고
    • Current approach to the treatment of human immunodeficiency virus-associated weight loss: Pathophysiologic considerations and emerging management strategies
    • HELLERSTEIN MK, KAHN J, MUDIE H, VITERI F: Current approach to the treatment of human immunodeficiency virus-associated weight loss: pathophysiologic considerations and emerging management strategies. Semin Oncol 17:17-33, 1990.
    • (1990) Semin Oncol , vol.17 , pp. 17-33
    • Hellerstein, M.K.1    Kahn, J.2    Mudie, H.3    Viteri, F.4
  • 32
    • 0023219278 scopus 로고
    • Predominance of helper-inducer T cells in mesenteric lymph nodes and intestinal lamina propria of normal nonhuman primates
    • JAMES SP, GRAEFF AS, ZEITZ M: Predominance of helper-inducer T cells in mesenteric lymph nodes and intestinal lamina propria of normal nonhuman primates. Cell Immunol 107:372-383, 1987.
    • (1987) Cell Immunol , vol.107 , pp. 372-383
    • James, S.P.1    Graeff, A.S.2    Zeitz, M.3
  • 33
    • 0030591587 scopus 로고    scopus 로고
    • Isolation and characterization of highly purified rat intestinal intraepithelial lymphocytes
    • KEARSEY JA, STADNYK AW: Isolation and characterization of highly purified rat intestinal intraepithelial lymphocytes. J Immunol Methods 194:35-48, 1996.
    • (1996) J Immunol Methods , vol.194 , pp. 35-48
    • Kearsey, J.A.1    Stadnyk, A.W.2
  • 34
    • 0030971242 scopus 로고    scopus 로고
    • Demonstration of the Th1 and Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry
    • KLEIN SA, DOEMEYER JM, DOBMEYER TS, PAPE M, OTTMANN OG, HELM EB, HOELZER D, ROSSOL R: Demonstration of the Th1 and Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry. Aids 11:1111-1118, 1997.
    • (1997) Aids , vol.11 , pp. 1111-1118
    • Klein, S.A.1    Doemeyer, J.M.2    Dobmeyer, T.S.3    Pape, M.4    Ottmann, O.G.5    Helm, E.B.6    Hoelzer, D.7    Rossol, R.8
  • 35
    • 0030916025 scopus 로고    scopus 로고
    • Analysis of cytokine producing activity of intestinal intraepithelial T cells from TCR beta-chain and delta-chain mutant mice
    • KOHYAMA M, HACHIMURA S, NANNO M, ISHIKAWA H, KAMINOGAWA S: Analysis of cytokine producing activity of intestinal intraepithelial T cells from TCR beta-chain and delta-chain mutant mice. Microbiol Immunol 41:353-359, 1997.
    • (1997) Microbiol Immunol , vol.41 , pp. 353-359
    • Kohyama, M.1    Hachimura, S.2    Nanno, M.3    Ishikawa, H.4    Kaminogawa, S.5
  • 36
    • 0025949779 scopus 로고
    • Detection, localization, and quantitation of HIV-associtated antigens in intestinal biopsies from patients with HIV
    • KOTKER DP, REKA S, BORCICH A, CRONIN WJ: Detection, localization, and quantitation of HIV-associtated antigens in intestinal biopsies from patients with HIV. Am J Pathol 139:823-830, 1991.
    • (1991) Am J Pathol , vol.139 , pp. 823-830
    • Kotker, D.P.1    Reka, S.2    Borcich, A.3    Cronin, W.J.4
  • 38
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enetrocollitis
    • KUHN R, LOHLER J, RENNICK D, RAJEWSKY K, MULLER W: Interleukin-10-deficient mice develop chronic enetrocollitis. Cell 75:263-274, 1993.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 39
    • 0025108695 scopus 로고
    • Animal models for AIDS
    • LETVIN NL: Animal models for AIDS. Immunol Today 11:322-326, 1990.
    • (1990) Immunol Today , vol.11 , pp. 322-326
    • Letvin, N.L.1
  • 41
    • 0030239819 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggest T helper 1 and cytotoxic functions
    • LUNDQVIST C, MELGAR S, YEUNG MM, HAMMARSTROM S, HAMMARSTROM ML: Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggest T helper 1 and cytotoxic functions. J Immunol 157:1926-1934, 1996.
    • (1996) J Immunol , vol.157 , pp. 1926-1934
    • Lundqvist, C.1    Melgar, S.2    Yeung, M.M.3    Hammarstrom, S.4    Hammarstrom, M.L.5
  • 42
    • 0024553788 scopus 로고
    • Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers
    • MADARA JL, STAFFORD J: Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 83:724-727, 1989.
    • (1989) J Clin Invest , vol.83 , pp. 724-727
    • Madara, J.L.1    Stafford, J.2
  • 44
    • 0028899454 scopus 로고
    • Bone marrow monocyte/macrophages are an early cellular target of pathogenic and nonpathogenic isolates of simian immunodeficiency virus (SIVmac) in rhesus macaques
    • MANDELL CP, JAIN NC, MILLER CJ, DANDEKAR S: Bone marrow monocyte/macrophages are an early cellular target of pathogenic and nonpathogenic isolates of simian immunodeficiency virus (SIVmac) in rhesus macaques. Lab Invest 72:323-333, 1995.
    • (1995) Lab Invest , vol.72 , pp. 323-333
    • Mandell, C.P.1    Jain, N.C.2    Miller, C.J.3    Dandekar, S.4
  • 45
    • 0030907897 scopus 로고    scopus 로고
    • Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis
    • MCDONALD SA, PALMEN MJ, VAN REES EP, MACUONALD TT: Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis. Immunology 91:73-80, 1997.
    • (1997) Immunology , vol.91 , pp. 73-80
    • Mcdonald, S.A.1    Palmen, M.J.2    Van Rees, E.P.3    Macuonald, T.T.4
  • 47
    • 0028561865 scopus 로고
    • Changes in cytokine release by CD4+ T cells in HIV1 infection
    • MEYAARD L, MIEDEMA F: Changes in cytokine release by CD4+ T cells in HIV1 infection. Res Immunol 145:607-611, 1994.
    • (1994) Res Immunol , vol.145 , pp. 607-611
    • Meyaard, L.1    Miedema, F.2
  • 49
    • 0026552488 scopus 로고
    • Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis
    • MULLIN GE, LAZENBY AJ, HARRIS ML, BAYLESS TM, JAMES SP: Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis. Gastroenterology 102:1620-1627, 1992.
    • (1992) Gastroenterology , vol.102 , pp. 1620-1627
    • Mullin, G.E.1    Lazenby, A.J.2    Harris, M.L.3    Bayless, T.M.4    James, S.P.5
  • 50
    • 0023874691 scopus 로고
    • Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms
    • NELSON JA, WILEY CA, REYNOLDS KC, REESE CE, MARGARETTEN W, LEVY JA: Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms. Lancet 1:259-262, 1988.
    • (1988) Lancet , vol.1 , pp. 259-262
    • Nelson, J.A.1    Wiley, C.A.2    Reynolds, K.C.3    Reese, C.E.4    Margaretten, W.5    Levy, J.A.6
  • 52
    • 0028559147 scopus 로고
    • Cytokine regulation of acute and chronic HIV infection in vitro: From cells lines to primary mononuclear cells
    • POLI G, KINTER AL, VICENZI E, FAUCI AS: Cytokine regulation of acute and chronic HIV infection in vitro: From cells lines to primary mononuclear cells. Res Immunol 145:578-582, 1994.
    • (1994) Res Immunol , vol.145 , pp. 578-582
    • Poli, G.1    Kinter, A.L.2    Vicenzi, E.3    Fauci, A.S.4
  • 53
    • 0029586280 scopus 로고
    • Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies
    • PRUSSIN C, METCALFE DD: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 188:117-128, 1995.
    • (1995) J Immunol Methods , vol.188 , pp. 117-128
    • Prussin, C.1    Metcalfe, D.D.2
  • 55
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • SADLACK B, MERZ H, SCHORLE H, SCHIMPL A, FELLER AC, HORAK I: Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75:253-261, 1993.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horak, I.6
  • 56
    • 0028303005 scopus 로고
    • Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia
    • SARWAR SR, DOHERTY PC: Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia. J Virol 68:3112-3119, 1994.
    • (1994) J Virol , vol.68 , pp. 3112-3119
    • Sarwar, S.R.1    Doherty, P.C.2
  • 57
    • 0028069352 scopus 로고
    • Cytokines in the Intestinal inflammation: Pathophysiological and clinical considerations
    • SARTOR RB: Cytokines in the Intestinal inflammation: Pathophysiological and clinical considerations. Gastroenterology 106:533-539, 1994.
    • (1994) Gastroenterology , vol.106 , pp. 533-539
    • Sartor, R.B.1
  • 58
    • 0028811367 scopus 로고
    • Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood
    • Berlin Diarrhea/Wasting Syndrome Study Group
    • SCHNEIDER T, JAHN HU, SCHMIDT W, RIECKEN EO, ZEITZ M, ULLRICH R: Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group. Gut 37:524-549, 1995.
    • (1995) Gut , vol.37 , pp. 524-549
    • Schneider, T.1    Jahn, H.U.2    Schmidt, W.3    Riecken, E.O.4    Zeitz, M.5    Ullrich, R.6
  • 59
    • 0028292762 scopus 로고
    • Abnormalities in subset distribution, activation, and differentiation of T cells isolated from large intestine biopsies in HIV infection
    • The Berlin Diarrhea/ Wasting Syndrome Study Group
    • SCHNEIDER T, ULLRICH R, BERGS C, SCHMIDT W, RIECKEN EO, ZEITZ M: Abnormalities in subset distribution, activation, and differentiation of T cells isolated from large intestine biopsies in HIV infection. The Berlin Diarrhea/ Wasting Syndrome Study Group. Clin Exp Immunol 95:430-435, 1994.
    • (1994) Clin Exp Immunol , vol.95 , pp. 430-435
    • Schneider, T.1    Ullrich, R.2    Bergs, C.3    Schmidt, W.4    Riecken, E.O.5    Zeitz, M.6
  • 62
    • 0026536326 scopus 로고
    • Pathologic featurs of SIV-induced disease and the association of macrophage infection with disease evolution
    • SIMON MA, CHALIFOUX LV, RINGLER DJ: Pathologic featurs of SIV-induced disease and the association of macrophage infection with disease evolution. AIDS Res Hum Retroviruses 8:327-337, 1992.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , pp. 327-337
    • Simon, M.A.1    Chalifoux, L.V.2    Ringler, D.J.3
  • 63
    • 0023928865 scopus 로고
    • Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etology and response to therapy
    • SMITH PD, LANE HC, GILL VJ, MANISCHEWITZ JF, QUINNAN GV, FAUCI A, MASUR H: Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etology and response to therapy. Ann Intern Med 108:328-333, 1988.
    • (1988) Ann Intern Med , vol.108 , pp. 328-333
    • Smith, P.D.1    Lane, H.C.2    Gill, V.J.3    Manischewitz, J.F.4    Quinnan, G.V.5    Fauci, A.6    Masur, H.7
  • 64
    • 0027981275 scopus 로고
    • Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques
    • STONE JD, HEISE CC, MILLER CJ, HALSTED CH, DANDEKAR S: Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques. Aids 8:1245-1256, 1994.
    • (1994) Aids , vol.8 , pp. 1245-1256
    • Stone, J.D.1    Heise, C.C.2    Miller, C.J.3    Halsted, C.H.4    Dandekar, S.5
  • 66
    • 0024336112 scopus 로고
    • Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): Evidence for HIV-induced enteropathy
    • ULLRICH R, ZEITZ M, HEISE W, L'AGE M, HOFFKEN G, RECKEN EO: Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy. Ann Intern Med 111:15-21, 1989.
    • (1989) Ann Intern Med , vol.111 , pp. 15-21
    • Ullrich, R.1    Zeitz, M.2    Heise, W.3    L'Age, M.4    Hoffken, G.5    Recken, E.O.6
  • 70
    • 0029129385 scopus 로고
    • Comparative sequence analysis of cytokine genes from human and nonhuman primates
    • VELLINGER F, BRAR SS, MAYNE A, CHIKKALA N, ANSAR AA: Comparative sequence analysis of cytokine genes from human and nonhuman primates. J Immunol 155:3946-3954, 1995.
    • (1995) J Immunol , vol.155 , pp. 3946-3954
    • Vellinger, F.1    Brar, S.S.2    Mayne, A.3    Chikkala, N.4    Ansar, A.A.5
  • 71
    • 0027788321 scopus 로고
    • Qualitative and quantitative studies of cytokines synthesized and secreted by non-human primate peripheral blood mononuclear cells
    • VILLINGER F, HUNT D, MAYNE A, VUCHETICH M, FINDLEY H, ANSARI AA: Qualitative and quantitative studies of cytokines synthesized and secreted by non-human primate peripheral blood mononuclear cells. Cytokine 5:469-479, 1993.
    • (1993) Cytokine , vol.5 , pp. 469-479
    • Villinger, F.1    Hunt, D.2    Mayne, A.3    Vuchetich, M.4    Findley, H.5    Ansari, A.A.6
  • 75
    • 0023871935 scopus 로고
    • Lymphocytes isolated from the intestinal lamina propria of normal non-human primates have increased expression of genes associated with T cell activation
    • ZEITZ M, GREEN WC, PEFFER NJ, JAMES SP: Lymphocytes isolated from the intestinal lamina propria of normal non-human primates have increased expression of genes associated with T cell activation. Gastroenterology 94: 647-655, 1988.
    • (1988) Gastroenterology , vol.94 , pp. 647-655
    • Zeitz, M.1    Green, W.C.2    Peffer, N.J.3    James, S.P.4
  • 76
    • 0028176064 scopus 로고
    • T-cell mediated immunopathology versus direct cytolysis by virus
    • ZINKERNAGEL RM, HENGARTNER H: T-cell mediated immunopathology versus direct cytolysis by virus. Immunol Today 15:262-268, 1994.
    • (1994) Immunol Today , vol.15 , pp. 262-268
    • Zinkernagel, R.M.1    Hengartner, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.