Characterization of a molecular clone of HIV type 2 infectious for Macaca nemestrina

AIDS Research and Human Retroviruses

Volumn 14, Issue 1, 1998, Pages 65-77

  Kraus, Günter ^a,b   Radaelli, Antonia ^a,c   Talbott, Randy ^a,d   Leavitt, Mark ^a,e   Schmidt, Ann ^f   Badel, Patricia ^a   Bartz, Curtis ^f   Morton, William ^f   Wong Staal, Flossie ^a   Looney, David J ^a,g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d BRISTOL MYERS SQUIBB   (United States)

^e Immusol Inc   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

^g VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERMINAL REPEAT; MACACA; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROVIRUS; VIREMIA;

EID: 0031984742     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1998.14.65     Document Type: Article

References (57)

1. Kanki P, M'Boup S, Marlink R, Travers K, Hsieh CC, Gueye A, Boye C, Sankale JL, Donnelly C, Leisenring W, Siby T, Thior I, Dia M, Gueye E-H, N'Doye I, and Essex M: Prevalence and risk determinants of human immunodeficiency virus type 2 (HIV-2) and human immunodeficiency virus type 1 (HIV-1) in West African female prostitutes. Am J Epidemiol 1992;136:895-907.
2. Naucler A, Albino P, Da Silva AP, Andreasson PA, Andersson S, and Biberfeld G: HIV-2 infection in hospitalized patients in Bissau, Guinea-Bissau. AIDS 1991;5:301-304.
3. Marlink RG, Ricard D, M'Boup S, Kanki PJ, Romet-Lemonne J-L, N'Doye I, Diop K, Simpson MA, Greco F, Chou M-J, DeGruttola V, Hsieh C-C, Boye C, Barin F, Denis F, McLane MF, and Essex M: Clinical, hematologic, and immunologic cross-sectional evaluation of individuals exposed to human immunodeficiency virus type-2 (HIV-2). AIDS Res Hum Retroviruses 1988;4:137-148.
4. Kanki PJ and De Cock K: Epidemiological and natural history of HIV-2. AIDS 1994;8:S85-S93.
5. Marlink R, Kanki P, Thior I, Travers K, Eisen G, Siby T, Traore I, Hsieh C-C, Dia MC, Gueye E-H, Hellinger J, Gueye-Ndiaye A, Sankale J-L, Ndoye I, M'Boup S, and Essex M: Reduced rate of disease development after HIV-2 infection as compared to HIV-1. Science 1994;265(5178):1587-1590.
6. Franchini G, Gurgo C, Guo HG, Gallo RC, Collalti E, Fargnoli KA, Hall LF, Wong-Staal F, and Reitz MS Jr: Sequence of simian immunodeficiency virus and its relationship to the human immunodeficiency viruses. Nature (London) 1987;328(6130):539-543.
7. Hirsch VM, Olmsted RA, Murphey-Corb M, Purcell RH, and Johnson PR: An African primate lentivirus (SIVsm) closely related to HIV-2. Nature (London) 1989;339:389-392.
8. Sharp PM, Robertson DL, Gao F, and Hahn BH: Origins and diversity of human immunodeficiency viruses. AIDS 1994;8: S27-S42.
9. Marcon L, Choe H, Martin KA, Farzan M, Ponath PD, Wu L, Newman W, Gerard N, Gerard C, and Sodroski J: Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239. J Virol 1997; 71(3):2522-2527.
10. Chen Z, Zhou P, Ho DD, Landau NR, and Marx PA: Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry. J Virol 1997;71(4):2705-2714.
11. Endres MJ, Ctapham PR, Marsh M, Ahuja M, Turner JD, McKnight A, Thomas JF, Stoebenau-Haggarty B, Choe S, Vance PJ, Wells TNC, Power CA, Sutterwala SS, Doms RW, Landau NR, and Hoxie JA: CD4-independent infection by HIV-2 is mediated by fusion/CXCR4. Cell 1996;87(4):745-756.
12. McKnight A, Wilkinson D, Simmons G, Talbot S, Picard L, Ahuja M, Marsh M, Hoxie JA, and Clapham PR: Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent. J Virol 1997;71(2):1692-1696.
13. Cocchi F, DeVico A, Garzino-Demo A, Arya SK, Gallo RC, and Lusso P: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995;270(5243):1811-1815.
14. Franchini G, Markham P, Gard E, Fargnoli K, Keubaruwa S, Jagodzinski L, Robert-Guroff M, Lusso P, Ford G, Wong-Staal F, and Gallo RC: Persistent infection of rhesus macaques with a molecular clone of human immunodeficiency virus type 2: Evidence of minimal genetic drift and low pathogenetic effects. J Virol 1990;64:4462-4467.
15. Putkonen P, Thorstensson R, Albert J, Hild K, Norrby E, Biberfeld P, and Biberfeld G: Infection of cynomolgus monkeys with HIV-2 protects against pathogenic consequences of a subsequent simian immunodeficiency virus infection. AIDS 1990;4:783-789.
16. Ho RJ, Agy MB, Morton WR, Scheibel M, McClure J, Watson A, Hu SL, Nosbisch C, Dorofeeva N, and Unadkat JD: Development of a chronically catheterized maternal-fetal macaque model to study in utero mother-to-fetus HIV transmission: A preliminary report. J Med Primatol 1996;25(3):218-224.
17. Livartowski J, Dormont D, Boussin F, Chamaret S, Guetard D, Vazeux R, Lebon P, Metivier H, and Montagnier L: Clinical and virological aspects of HIV2 infection in rhesus monkeys. Cancer Detect Prevent 1992;16(5-6):341-345.
18. Petry H, Jurkiewicz E, Makoschey B, Stahl-Hennig C, Coulibaly C, Luke W, Dittmer U, and Hunsmann G: Activation of HIV-2ben by superinfection with SIVmac251/32H is correlated with protection against disease in macaques. In: Vaccines '94. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1994, pp. 243-246.
19. Castro BA, Nepomuceno M, Lerche NW, Eichberg JW, and Levy JA: Persistent infection of baboons and rhesus monkeys with different strains of HIV-2. Virology 1991;184:219-226.
20. Otten RA, Brown BG, Simon M, Lupo LD, Parekh BS, Lairmore MD, Schable CA, Schochetman G, and Rayfield MA: Differential replication and pathogenic effects of HIV-1 and HIV-2 in Macaca nemestrina. AIDS 1994;8(3):297-306.
21. Agy MB, Frumkin LR, Corey L, Coombs RW, Wolinsky SM, Koehler J, Morton WR, and Katze MG: Infection of Macaca nemestrina by human immunodeficiency virus type-1. Science 1992;257(5066):103-106.
22. Reimann KA, Li JT, Veazey R, Halloran M, Park IW, Karlsson GB, Sodroski J, and Letvin NL: A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J Virol 1996; 70(1):6922-6928.
23. Dunn CS, Beyer C, Kieny MP, Gloeckler L, Schmitt D, Gut JP, Kim A, and Aubertin AM: High viral load and CD4 lymphopenia in rhesus and cynomolgus macaques infected by a chimeric primate lentivirus constructed using the env, rev, tat, and vpu genes from HIV-1 Lai. Virology 1996;223(2):351-361.
24. Joag SV, Li Z, Foresman L, Stephens EB, Zhao LJ, Adany I, Pinson DM, McClure HM and Narayan O: Chimeric simian/human immunodeficiency virus that causes progressive loss of CD44+ T cells and AIDS in pig-tailed macaques. J Virol 1996;70(5): 3189-3197.
25. Stahl-Hennig C, Herchenroder O, Nick S, Evers M, Stille-Siegener M, Jentsch KD, Kirchhoff F, Tolle T, Gatesman TJ, Luke W, and Hunsmann G: Experimental infection of macaques with HIV-2ben G, a novel HIV-2 isolate. AIDS 1990;4:611-617.
26. Petry H, Dittmer U, Stahl-Hennig C, Coulibaly C, Makoschey B, Fuchs D, Wachter H, Tolle T, Morys-Wortmann C, Kaup FJ, Jurkiewicz E, Luke W, and Hunsmann G: Reactivation of human immunodeficiency virus type 2 in macaques after simian immunodeficiency virus SIVmac superinfection. J Virol 1995;69:1564-1574.
27. Putkonen P, Walther L, Zhang YJ, Li SL, Nilsson C, Albert J, Biberfeld P, Thorstensson R, and Biberfeld G: Long-term protection against SIV-induced disease in macaques vaccinated with a live attenuated HIV-2 vaccine. Nature Med 1995;1:914-918.
28. Barnett SW, Murthy KK, Herndier BG, and Levy JA: An AIDS-like condition induced in baboons by HIV-2. Science 1994; 266:642-646.
29. Franchini G, Fargnoli KA, Giombini F, Jagodzinski L, De Rossi A, Bosch M, Biberfeld G, Fenyö EM, Albert J, Gallo RC, and Wong-Staal F: Molecular and biological characterization of a replication competent human immunodeficiency type 2 (HIV-2) clone. Proc Natl Acad Sci USA 1989;86:2433-2437.
30. Barnett SW, Quiroga M, Werner A, Dina D, and Levy JA: Distinguishing features of an infectious molecular clone of the highly divergent and noncytopathic human immunodeficiency virus type 2 UC1 strain. J Virol 1993;67:1006-1014.
31. Kuhnel H, von Briesen H, Dietrich U, Adamski M, Mix D, Biesert L, Kreutz R, Immelmann A, Henco K, Meichsner C, Andreesen R, Gelderblom H, and Rubsamen-Waigmann H: Molecular cloning of two West African human immunodeficiency virus type 2 isolates that replicate well in macrophages: A Gambian isolate, from a patient with neurologic acquired immunodeficiency syndrome, and a highly divergent Ghanian isolate. Proc Natl Acad Sci USA 1989;86:2383-2387.
32. Kumar P, Hui H, Kappes JC, Haggarty BS, Hoxie JA, Arya SK, Shaw GM, and Hahn BH: Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate. J Virol 1990;64:890-901.
33. Kirchhoff F, Jentsch KD, Bachmann B, Stuke A, Laloux C, Luke W, Stahl-Hennig C, Schneider J, Nieselt K, Eigen M, and Hunsmann G: A novel proviral clone of HIV-2: Biological and phylogenetic relationship to other primate immunodeficiency viruses. Virology 1990;177(1):305-311.
34. Vogt G, le Grand R, Vaslin B, Boussin F, Auboyer MH, Riviere Y, Putkonen P, Sonigo P, Kieny MP, Girard M, and Dormont D: Heterologous HIV-2 challenge of rhesus monkeys immunized with recombinant vaccinia viruses and purified recombinant HIV-2 proteins. Vaccine 1995;13:202-208.
35. Abimiku AG, Franchini G, Tartaglia J, Aldrich K, Myagkikh M, Markham PD, Chong P, Klein M, Kieny PM, Paoletti E, Gallo RC, and Robert-Guroff M: HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques. Nature Med 1995;1:321-329.
36. Putkonen P, Nilsson C, Walther L, Ghavamzadeh L, Hild K, Broliden K, Biberfeld G, and Thorstensson R: Efficacy of inactivated whole HIV-2 vaccines with various adjuvants in cynomolgus monkeys. J Med Primatol 1994;23:89-94.
37. Looney DJ, McClure J, Kent SJ, Radaelli A, Kraus G, Schmidt A, Steffy K, Greenberg P, Hu S-L, Morton WM, and Wong-Staal F: A minimally replicative HIV-2 live-virus vaccine protects M. nemestrina from disease after HIV-2287 challenge. Virology 1998; accepted.
38. Radaelli A, Kraus G, Schmidt A, Badel P, McClure J, Hu S-L, Morton WM, De Giuli Morghen C, Wong-Staal F, and Looney DJ: Genetic variation in an HIV-2 live-virus M. nemestrina vaccine model. Submitted (1998).
39. Corpet F: Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res 1988;16:10881-10890.
40. Pearson WR: Using the FASTA program to search protein and DNA sequence databases. Methods Mol Biol 1994;24:307-331.
41. Felsenstein J: PHYUP (Phytogeny Inference Package), version 3.5c. Copyright J Felsenstein and the Department of Genetics, University of Washington, Seattle, Washington, 1993.
42. Novembre FJ, Hirsch VM, McClure HM, and Johnson PR: Molecular diversity of SIVsmm/PBj and a cognate variant, SIVsmm/PGg. J Med Primatol 1991;20:188-192.
43. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, and Berger EA: CC CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996;272(5270):1955-1958.
44. Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, Cayanan C, Maddon PJ, Koup RA, Moore JP, and Paxton WA: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature (London) 1996;381(6584):667-673.
45. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis C, Peiper SC, Schall TJ, Littman DR, and Landau NR: Identification of a major coreceptor for primary isolates of HIV-1. Nature (London) 1996;381(6584):661-666.
46. Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, and Doms RW: A dual-tropic primarily HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996;85(7):1149-1158.
47. Feng Y, Broder CC, Kennedy PE, and Berger EA: HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996;272(5263):872-877.
48. Kong LI, Lee SW, Kappes JC, Parkin JS, Decker D, Hoxie JA, Hahn BH, and Shaw GM: West African HIV-2-related human retrovirus with attenuated cytopathicity. Science 1988;240:1525-1529.
49. Mulligan MJ, Kumar P, Hui HX, Owens RJ, Ritter GD Jr, Hahn BH, and Compans RW: The Env protein of an infectious noncytopathic HIV-2 is deficient in syncytium formation. Aids Res Hum Retroviruses 1990;6:707-720.
50. Hoxie JA, Brass LF, Pletcher CH, Haggarty BS, and Hahn BH: Cytopathic variants of an attenuated isolate of human immunodeficiency virus type 2 exhibit increased affinity for CD4. J Virol 1991;65(9):5096-5101.
51. Chakrabarti L, Emerman M, Tiollais P, and Sonigo P: The cytoplasmic domain of simian immunodeficiency virus transmembrane protein modulates infectivity. J Virol 1989;63:4395-4403.
52. Mulligan MJ, Yamshchikov GV, Ritter GD Jr, Gao F, Jin MJ, Nail CD, Spies CP, Hahn BH, and Compans RW: Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types. J Virol 1992;66:3971-3975.
53. Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, and Desrosiers RC: Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 1992;258:1938-1941.
54. Marthas ML, Miller CJ, Sutjipto S, Higgins J, Torten J, Lohman BL, Unger RE, Ramos RA, Kyono H, McGhee JR, Marx P, and Pedersen N: Efficacy of live-attenuated and whole-inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV. J Med Primatol 1992;21:99-107.
55. Clements JE, Montelaro RC, Zink MC, Amedee AM, Miller S, Trichel AM, Jagerski B, Hauer D, Martin LN, Bohm RP, and Murphy-Corb M: Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus. J Virol 1995;69:2737-2744.
56. Wyand MS, Manson KH, Garcia-Moll M, Montefiori D, and Desrosiers RC: Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J Virol 1996;70:3724-3733.
57. Baba TW, Trichel AM, An L, Liska V, Martin LN, Murphey-Corb M, and Ruprecht RM: Infection and AIDS in adult macaques after nontraumatic oral exposure to cell-free SIV. Science 1996;272(5267):1486-1489.