A minimally replicative HIV-2 live-virus vaccine protects M. nemestrina from disease after HIV-2287 challenge

Virology

Volumn 242, Issue 1, 1998, Pages 150-160

  Looney, David J ^a,b,f   McClure, Jan ^d   Kent, Stephen J ^e   Radaelli, Antonia ^b,c   Kraus, Günter ^b,g   Schmidt, Ann ^e   Steffy, Kevin ^b,h   Greenberg, Phillip ^e   Hu, Shiu Lok ^d   Morton, William R ^e   Wong Staal, Flossie ^b  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d BRISTOL MYERS SQUIBB   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g UNIVERSITY OF MIAMI   (United States)

^h ABBOTT LABORATORIES   (United States)

Author keywords

Animal models; HIV 2; Vaccine; Virology quantitative

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LIVE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNIZATION; INFECTION PREVENTION; MACACA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS REPLICATION; VIRUS TITRATION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 2; MACACA; MACACA NEMESTRINA; RNA VIRUSES;

EID: 0032029779     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8992     Document Type: Article

References (43)

1. Abimiku A. G., Franchini G., Tartaglia J., Aldrich K., Myagkikh M., Markham P. D., Chong P., Klein M., Kieny P. M., Paoletti E., Gallo R. C., Robert-Guroff M. HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques. Nature Med. 1:1995;321-329.
2. Almond N., Kent K., Cranage M., Rud E., Clarke B., Stott E. J. Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. Lancet. 345:1995;1342-1344.
3. Baba T. W., Jeong Y. S., Pennick D., Bronson R., Greene M. F., Ruprecht R. M. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science. 267:1995;1820-1825.
4. Cao Y., Qin L., Zhang L., Safrit J., Ho D. D. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332:1995;201-208.
5. Chesebro B., Wehrly K., Metcalf J., Griffin D. E. Use of a new CD4-positive HeLa cell clone for direct quantitation of infectious human immunodeficiency virus from blood cells of AIDS patients. J. Infect. Dis. 163:1991;64-70.
6. Clements J. E., Montelaro R. C., Zink M. C., Amedee A. M., Miller S., Trichel A. M., Jagerski B., Hauer D., Martin L. N., Bohm R. P., Murphy-Corb M. Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus. J. Virol. 69:1995;2737-2744.
7. Daniel M. D., Kirchhoff F., Czajak S. C., Sehgal P. K., Desrosiers R. C. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science. 258:1992;1938-1941.
8. Gallimore A., Cranage M., Cook N., Almond N., Bootman J., Rud E., Silvera P., Dennis M., Corcoran T., Stott J., McMichael A., Gotch F. Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques. Nature Med. 1:1995;1167-1173.
9. Heeney J. L., van Els C., de Vries P., ten Haaft P., Otting N., Koornstra W., Boes J., Dubbes R., Niphuis H., Dings M., Cranage M., Norley S., Jonker M., Bontrop R. E., Osterhaus A. Major histocompatibility complex class I-associated vaccine protection from simian immunodeficiency virus-infected peripheral blood cells. J. Exp. Med. 180:1994;769-774.
10. Hirsch V. M., Fuerst T. R., Sutter G., Carroll M. W., Yang L. C., Goldstein S., Piatak M. Jr., Elkins W. R., Alvord W. G., Montefiori D. C., Moss B., Lifson J. D. Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: Effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara. J. Virol. 70:1996;3741-3752.
11. Ho R. J. Y., Agy M. B., Morton W. R., Scheibel M., McClure J., Watson A., Hu S.-L., Nobisch C., Dorofeeva N., Unadkat J. D. Development of a chronically catheterized maternal-fetal macaque model to study in utero mother-to-fetus HIV transmission: A preliminary report. J. Med. Primatol. 25:1996;218-224.
12. Hu S. L., Abrams K., Barber G. N., Moran P., Zarling J. M., Langlois A. J., Kuller L., Morton W. R., Benveniste R. E. Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science. 255:1992a;456-459.
13. Hu S. L., Abrams K., Misher L., Stallard V., Moran P., Zarling J. M., Langlois A. J., Kuller L., Morton W. R., Benveniste R. E. Evaluation of protective efficacy of recombinant subunit vaccines against simian immunodeficiency virus infection of macaques. J. Med. Primatol. 21:1992b;119-125.
14. Hu S. L., Stallard V., Abrams K., Barber G. N., Kuller L., Langlois A. J., Morton W. R., Benveniste R. E. Protection of vaccinia-primed macaques against SIVmne infection by combination immunization with recombinant vaccinia virus and SIVmne gp160. J. Med. Primatol. 22:1993;92-99.
15. Hulskotte E. G., Geretti A. M., Siebelink K. H., van Amerongen G., Cranage M. P., Rud E. W., Norley S. G., de Vries P., Osterhaus A. D. Vaccine-induced virus-neutralizing antibodies and cytotoxic T cells do not protect macaques from experimental infection with simian immunodeficiency virus SIVmac32H (J5). J. Virol. 69:1995;6289-6296.
16. Israel Z. R., Edmonson P. F., Maul D. H., O'Neil S. P., Mossman S. P., Thiriart C., Fabry L., Van Opstal O., Bruck C., Bex F., Burny A., Fultz P. N., Mullins J. I., Hoover E. A. Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines. J. Virol. 68:1994;1843-1853.
17. Johnson R. P. Macaque models for AIDS vaccine development. Curr. Opin. Immunol. 8:1996;554-560.
18. Kent S. J., Corey L., Agy M. B., Morton W. R., McElrath M. J., Greenberg P. D. Cytotoxic and proliferative T cell responses in HIV-1-infectedMacaca nemestrina. J. Clin. Invest. 95:1995;248-256.
19. Kent S. J., Hu S.-L., Corey L., Morton W. R., Greenberg P. D. Detection of simian immunodeficiency virus (SIV)-specific CD8+ T cells in macaques protected from SIV challenge. J. Virol. 70:1996;4941-4947.
20. Kimpton J., Emerman M. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66:1992;2232-2239.
21. Kraus G., Radaelli A., Leavitt M., Talbott R., Badel P., Schmidt A., Bartz C., Morton W., Wong-Staal F., Looney D. J. Characterization of a novel molecular clone of HIV-2 infectious forMacaca nemestrina. Aids Res. Hum. Retroviruses. 14:1998;65-77.
22. Lehner T., Wang Y., Crang M., Bergmeier L. A., Michell E., Tao L., Hall G., Dennis M., Cook N., Brookes R., Klavinskis L., Jones I., Doyle C., Ward R. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nature Med. 2:1996;767-775.
23. Letvin N. L., Li J., Halloran M., Cranage M. P., Rud E. W., Sodroski J. Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus. J. Virol. 69:1995;4569-4571.
24. Lohman B. L., McChesney M. B., Miller C. J., McGowan E., Joye S. M., Van Rompay K. K., Reay E., Antipa L., Pedersen N. C., Marthas M. L. A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge. J. Virol. 68:1994;7021-7029.
25. Lu S., Arthos J., Montefiori D. C., Yasutomi Y., Manson K., Mustafa F., Johnson E., Santoro J. C., Wissink J., Mullins J. I., Haynes J. R., Letvin N. L., Wyand M., Robinson L. H. Simian immunodeficiency virus DNA vaccine trial in macaques. J. Virol. 70:1996;3978-3991.
26. Mackett M., Smith G. L., Moss B. General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes. J. Virol. 49:1984;857-864.
27. Marthas M. L., Miller C. J., Sutjipto S., Higgins J., Torten J., Lohman B. L., Unger R. E., Kiyono H., Ramos R. A., McGhee J. R., Marx P., Pedersen N. Efficacy of live-attenuated and whole-inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV. J. Med. Primatol. 21:1992;99-107.
28. Marthas M. L., Sutjipto S., Higgins J., Lohman B., Torten J., Luciw P. A., Marx P. A., Pedersen N. C. Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV. J. Virol. 64:1990;3694-3700.
29. Mellors J. W., Rinaldo C. Jr., Gupta P., White R. M., Todd J. A., Kingsley L. A. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science. 272:1996;1167-1170.
30. Mossman S. P., Bex F., Berglund P., Arthos J., O'Neil S. P., Riley D., Maul D. H., Bruck C., Momin P., Burny A., Fultz P. N., Mullins J. I., Lijestrom P., Hoover E. A. Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J. Virol. 70:1996;1953-1960.
31. Panicali D., Paoletti E. Construction of poxviruses as cloning vectors: Insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. Proc. Natl. Acad. Sci. USA. 79:1982;4927-4931.
32. Petry H., Dittmer U., Stahl-Hennig C., Coulibaly C., Makoschey B., Fuchs D., Wachter H., Tolle T., Morys-Wortmann C., Kaup F. J., Jurkiewicz E., Luke W., Hunsmann G. Reactivation of human immunodeficiency virus type 2 in macaques after simian immunodeficiency virus SIVmac superinfection. J. Virol. 69:1995;1564-1574.
33. Putkonen P., Thorstensson R., Albert J., Hild K., Norrby E., Biberfeld P., Biberfeld G. Infection of cynomolgus monkeys with HIV-2 protects against pathogenic consequences of a subsequent simian immunodeficiency virus infection. AIDS. 4:1990;783-789.
34. Putkonen P., Walther L., Zhang Y. J., Li S. L., Nilsson C., Albert J., Biberfeld P., Thorstensson R., Biberfeld G. Long-term protection against SIV-induced disease in macaques vaccinated with a live attenuated HIV-2 vaccine. Nature Med. 1:1995;914-918.
35. Putkonen P., Nilsson C., Makitalo B., Biberfeld G., Thorstensson R., Cranage M., Erling R. Immunization with live attenuated SIVmac can protecte macaques against mucosal infection with SIVsm. Vaccines 1996. 1996;Cold Spring Harbor Laboratory Press, Cold Spring Harbor. p. 205-209.
36. Reimann K. A., Tenner-Racz K., Racz P., Montefiori D. C., Yasutomi Y., Lin W., Ransil B. J., Letvin N. L. Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques. J. Virol. 68:1994;2362-2370.
37. Rinaldo C., Huang X. L., Fan Z. F., Ding M., Beltz L., Logar A., Panicali D., Mazzara G., Liebmann J., Cottrill M., Phalguni G. High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors. J. Virol. 69:1995;5838-5842.
38. Sattentau Q. J. Neutralization of HIV-1 by antibody. Curr. Opin. Immunol. 8:1996;540-545.
39. Steffy K. R., Kraus G., Looney D. J., Wong-Staal F. Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2. J. Virol. 66:1992;4532-4535.
40. Vogt G., le Grand R., Vaslin B., Boussin F., Auboyer M. H., Riviere Y., Putkonen P., Sonigo P., Kieny M. P., Girard M., Dormont D. Heterologous HIV-2 challenge of rhesus monkeys immunized with recombinant vaccinia viruses and purified recombinant HIV-2 proteins. Vaccine. 13:1995;202-208.
41. Weir J. P., Bajszar G., Moss B. Mapping of the vaccinia virus thymidine kinase gene by marker rescue and by cell-free translation of selected mRNA. Proc. Natl. Acad. Sci. USA. 79:1982;1210-1214.
42. Wyand M. S., Manson K. H., Garcia-Moll M., Montefiori D., Desrosiers R. C. Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J. Virol. 70:1996;3724-3733.
43. Yasutomi Y., Koenig S., Woods R. M., Madsen J., Wassef N. M., Alving C. R., Klein H. J., Nolan T. E., Boots L. J., Kessler J. A., Emini E. A., Conley A. J., Letvin N. L. A vaccine-elicited, single viral epitope-specific cytotoxic T lymphocyte response does not protect against intravenous, cell-free simian immunodeficiency virus challenge. J. Virol. 69:1995;2279-2284.