메뉴 건너뛰기




Volumn 123, Issue 2, 1998, Pages 205-214

Pharmacological analysis of the haemodynamic effects of 5-HT(1B/D) receptor agonists in the normotensive rat

Author keywords

5 HT(1A) receptors; 5 HT(1B D) receptors; Bradycardia; GR 127935; Hypotension; Rizatriptan; Sumatriptan; WAY 100635; Zolmitriptan

Indexed keywords

ANGIOTENSIN; ATROPINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PENTOBARBITAL; RIZATRIPTAN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B AGONIST; SEROTONIN 1D RECEPTOR; SEROTONIN AGONIST; SUMATRIPTAN; ZOLMITRIPTAN;

EID: 0031975780     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701593     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 0028988252 scopus 로고
    • 1-like receptors mediating vasoconstriction and vasodilatation: Their characterization and distribution in the intact canine cardiovascular system
    • 1-like receptors mediating vasoconstriction and vasodilatation: their characterization and distribution in the intact canine cardiovascular system. Br. J. Pharmacol., 114, 961-968.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 961-968
    • Cambridge, D.1    Whiting, M.V.2    Butterfield, L.J.3    Marston, C.4
  • 2
    • 0030598628 scopus 로고    scopus 로고
    • 1-like receptor agonist sumatriptan in anesthetized rabbits
    • 1-like receptor agonist sumatriptan in anesthetized rabbits. Eur. J. Pharmacol., 304, 87-92.
    • (1996) Eur. J. Pharmacol. , vol.304 , pp. 87-92
    • Choppin, A.1    O'Connor, S.E.2
  • 3
    • 0025145405 scopus 로고
    • Studies on the site and mechanism of the sympatholytic action of 8-OH-DPAT
    • CLEMENT, M.E. & MCCALL, R.B. (1990). Studies on the site and mechanism of the sympatholytic action of 8-OH-DPAT. Brain Res., 525, 232-241.
    • (1990) Brain Res. , vol.525 , pp. 232-241
    • Clement, M.E.1    Mccall, R.B.2
  • 4
    • 0026739902 scopus 로고
    • Evidence that the lateral tegmental field plays an important role in the central sympathoinhibitory action of 8-OH-DPAT
    • CLEMENT, M.E. & MCCALL, R.B. (1992). Evidence that the lateral tegmental field plays an important role in the central sympathoinhibitory action of 8-OH-DPAT. Brain Res., 587, 115-122.
    • (1992) Brain Res. , vol.587 , pp. 115-122
    • Clement, M.E.1    Mccall, R.B.2
  • 6
    • 0027336568 scopus 로고
    • 1B receptors mediate potent contractile responses to 5-HT in rat caudal artery
    • 1B receptors mediate potent contractile responses to 5-HT in rat caudal artery. Br. J. Pharmacol., 109, 609-611.
    • (1993) Br. J. Pharmacol. , vol.109 , pp. 609-611
    • Craig, D.A.1    Martin, G.R.2
  • 11
    • 0026657267 scopus 로고
    • Lack of effect of the antimigraine drugs, sumatriptan, ergotamine and dihydroergotamine on arteriovenous anastomotic shunting in the dura mater of the pig
    • DEN BOER, M.O., SOMERS, J.A.E. & SAXENA, P.R. (1992). Lack of effect of the antimigraine drugs, sumatriptan, ergotamine and dihydroergotamine on arteriovenous anastomotic shunting in the dura mater of the pig. Br. J. Pharmacol., 107, 577-583.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 577-583
    • Den Boer, M.O.1    Somers, J.A.E.2    Saxena, P.R.3
  • 12
    • 0031043405 scopus 로고    scopus 로고
    • The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90)in healthy volunteers
    • DIXON, R., GILLOTIN, C., GIBBENS, M., POSNER, J. & PECK, R.W. (1997). The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90)in healthy volunteers. Br. J. Clin. Pharmacol., 43, 273-281.
    • (1997) Br. J. Clin. Pharmacol. , vol.43 , pp. 273-281
    • Dixon, R.1    Gillotin, C.2    Gibbens, M.3    Posner, J.4    Peck, R.W.5
  • 13
    • 0027419370 scopus 로고
    • Clinical and experimental effects of sumatriptan in humans
    • FERRARI, M.D. & SAXENA, P.R. (1993). Clinical and experimental effects of sumatriptan in humans. Trends Pharmacol. Sci., 14, 129-133.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 129-133
    • Ferrari, M.D.1    Saxena, P.R.2
  • 15
    • 0023106392 scopus 로고
    • Cardiovascular response to 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in the rat: Site of action and pharmalogical analysis
    • FOZARD, J.R., MIR, A.K & MIDDLEMISS, D.N. (1987). Cardiovascular response to 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in the rat: site of action and pharmalogical analysis. J. Cardiovasc. Pharmacol., 9, 328-347.
    • (1987) J. Cardiovasc. Pharmacol. , vol.9 , pp. 328-347
    • Fozard, J.R.1    Mir, A.K.2    Middlemiss, D.N.3
  • 16
    • 84989498101 scopus 로고
    • 1A receptors with DP-5-CT and sumatriptan in anaesthetized rats
    • 1A receptors with DP-5-CT and sumatriptan in anaesthetized rats. Br. J. Pharmacol., 114, P448.
    • (1995) Br. J. Pharmacol. , vol.114
    • Gallacher, M.1    Ramage, A.G.2
  • 18
    • 0030272955 scopus 로고    scopus 로고
    • 1B/D receptor agonist zolmitriptan (311C90): Are brain stem sites therapeutic target in migraine?
    • 1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine? Pain, 67, 355-359.
    • (1996) Pain , vol.67 , pp. 355-359
    • Goadsby, P.J.1    Hoskin, K.L.2
  • 19
    • 0021873206 scopus 로고
    • Acute administration of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a selective 5-HT receptor agonist in Sprague-Dawley rat and the spontaneously hypertensive rat
    • GRADIN, K., PETTERSON, A., HEDNER, T. & PERSSON, B. (1985). Acute administration of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a selective 5-HT receptor agonist in Sprague-Dawley rat and the spontaneously hypertensive rat. J. Neural Transm., 62, 305-319.
    • (1985) J. Neural Transm. , vol.62 , pp. 305-319
    • Gradin, K.1    Petterson, A.2    Hedner, T.3    Persson, B.4
  • 20
    • 0027394053 scopus 로고
    • 1A receptor activation: Ventral medullary sites and mechanisms of action in the rat
    • 1A receptor activation: ventral medullary sites and mechanisms of action in the rat. J. Auton. Nerv. Syst., 42, 177-188.
    • (1993) J. Auton. Nerv. Syst. , vol.42 , pp. 177-188
    • Helke, C.J.1    Mcdonald, C.H.2    Phillips, E.T.3
  • 23
    • 0025767979 scopus 로고
    • The effects of 8-OH-DPAT on medullary 5-HT neurones and sympathetic activity in baroreceptor-denervated animals
    • KING, K.A. & MCCALL, R.B. (1991). The effects of 8-OH-DPAT on medullary 5-HT neurones and sympathetic activity in baroreceptor-denervated animals. Eur. J. Pharmacol., 200, 357-360.
    • (1991) Eur. J. Pharmacol. , vol.200 , pp. 357-360
    • King, K.A.1    Mccall, R.B.2
  • 26
    • 0023525983 scopus 로고
    • 2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity
    • 2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity. J. Pharmacol. Exp. Ther., 242, 1152-1159.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 1152-1159
    • Mccall, R.B.1    Patel, N.P.2    Harris, L.T.3
  • 30
    • 0024516042 scopus 로고
    • Overview of initial clinical studies with intravenous and oral GR43175 in acute migraine
    • PERRIN, V.L., FARKKILA, M., GOASGUEN, J., DOENICKE, A., BRAND, J. & TFELT-HANSEN, P. (1989). Overview of initial clinical studies with intravenous and oral GR43175 in acute migraine. Cephalalgia, 9 (Suppl 9), 63-72.
    • (1989) Cephalalgia , vol.9 , Issue.9 SUPPL. , pp. 63-72
    • Perrin, V.L.1    Farkkila, M.2    Goasguen, J.3    Doenicke, A.4    Brand, J.5    Tfelt-Hansen, P.6
  • 31
    • 0023235785 scopus 로고
    • 1A receptor agonist 8OH-DPAT and ipsapirone have a central hypotensive action that differs from that of clonidine in anesthetized cats
    • 1A receptor agonist 8OH-DPAT and ipsapirone have a central hypotensive action that differs from that of clonidine in anesthetized cats. Eur. J. Pharmacol., 138, 179-191.
    • (1987) Eur. J. Pharmacol. , vol.138 , pp. 179-191
    • Ramage, A.G.1    Fozard, J.R.2
  • 32
    • 0025129981 scopus 로고
    • Cardiovascular effects of serotonin agonists and antagonists
    • SAXENA, P.R. & VILLALON, C.M. (1990). Cardiovascular effects of serotonin agonists and antagonists. J. Cardiovasc. Pharmacol., 15, (Suppl. 7)S17-S34.
    • (1990) J. Cardiovasc. Pharmacol. , vol.15 , Issue.7 SUPPL.
    • Saxena, P.R.1    Villalon, C.M.2
  • 36
    • 0030610298 scopus 로고    scopus 로고
    • 7 receptors in the long-lasting hypotensive response induced by 5-hydroxytryptamine in the rat
    • 7 receptors in the long-lasting hypotensive response induced by 5-hydroxytryptamine in the rat. Br. J. Pharmacol., 121, 563-571.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 563-571
    • Terron, J.A.1
  • 37
    • 0026612128 scopus 로고
    • 1 binding sites in autonomic areas of the rat dorsomedial medulla oblongata
    • 1 binding sites in autonomic areas of the rat dorsomedial medulla oblongata. Synapse, 10, 217-227.
    • (1992) Synapse , vol.10 , pp. 217-227
    • Thor, K.B.1    Blitz-Siebert, A.2    Helke, C.J.3
  • 40
    • 0030593942 scopus 로고    scopus 로고
    • Nitric oxide regulation of TP receptor-mediated pulmonary vasoconstriction in the anesthetized, open chest rat
    • VALENTIN, J.P., BESSAC, A.M., MAFFRE, M. & JOHN, G.W. (1996a). Nitric oxide regulation of TP receptor-mediated pulmonary vasoconstriction in the anesthetized, open chest rat. Eur. J. Pharmacol., 317, 335-342.
    • (1996) Eur. J. Pharmacol. , vol.317 , pp. 335-342
    • Valentin, J.P.1    Bessac, A.M.2    Maffre, M.3    John, G.W.4
  • 42
    • 0343413503 scopus 로고
    • 1B/D receptor agonists, sumatriptan and naratriptan in anesthetized, open-chest pigs
    • 1B/D receptor agonists, sumatriptan and naratriptan in anesthetized, open-chest pigs. Cephalalgia, 15 (Suppl 14), 210.
    • (1995) Cephalalgia , vol.15 , Issue.14 SUPPL. , pp. 210
    • Verscheure, Y.1    De Courtois, F.2    John, G.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.