Agonist activity of antimigraine drugs at recombinant human 5-HT(1A) receptors: Potential implications for prophylactic and acute therapy

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 355, Issue 6, 1997, Pages 682-688

  Newman Tancredi, A ^a   Conte, C ^a   Chaput, C ^a   Verfiele L ^a   Audinot Bouchez, V ^a   Lochon, S ^a   Lavielle, G ^a   Millan, M J ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

5 HT(1A) Receptors; 5HT(1D) Receptors; 35S GTP S Binding; Alniditan; GR 127,935; Migraine; Naratriptan; Sumatriptan

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; 3 [3 (2 DIMETHYLAMINOETHYL) 1H INDOL 5 YL] N (4 METHOXYBENZYL)ACRYLAMIDE; 5 FLUORO 3 [3 [4 (5 METHOXY 4 PYRIMIDINYL) 1 PIPERAZINYL]PROPYL] 1H INDOLE; ANTIMIGRAINE AGENT; DIHYDROERGOTAMINE; LISURIDE; METHYSERGIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 [5 [3 (2 AMINOETHYL) 1H INDOL 5 YL] 1,2,4 OXADIAZOL 3 YL]BENZYL]METHANESULFONAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 3 METHYL 4 (4 PYRIDYL)BENZAMIDE; NARATRIPTAN; PHOSPHOLAMBAN; PIZOTIFEN; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HEADACHE; MIGRAINE; NONHUMAN; RECEPTOR AFFINITY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BENZOPYRANS; BINDING, COMPETITIVE; CELL MEMBRANE; CRICETINAE; DIHYDROERGOTAMINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUINEA PIGS; HUMANS; INDOLES; LISURIDE; METHYSERGIDE; MIGRAINE DISORDERS; PIPERAZINES; PIPERIDINES; PIZOTYLINE; PROPRANOLOL; PROPYLAMINES; PROTEIN BINDING; PYRIDINES; PYRIMIDINES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RECOMBINANT PROTEINS; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SUMATRIPTAN; TRYPTAMINES;

EID: 0030776682     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005000     Document Type: Article

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