Efficacy of inverse agonists in cells overexpressing a constitutively active β2-adrenoceptor and type II adenylyl cyclase

British Journal of Pharmacology

Volumn 123, Issue 2, 1998, Pages 335-343

  Stevens, Patricia A ^a   Milligan, Graeme ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

2 adrenoceptor; Constitutively active mutant receptor; Inverse agonist; NG108 15 cells; Type II adenylyl cyclase

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADENYLATE CYCLASE; ALKYLATING AGENT; ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BETAXOLOL; FORSKOLIN; ISOPRENALINE; PROPRANOLOL; SOTALOL; TIMOLOL;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; ENZYME ACTIVITY; GENETIC TRANSFECTION; GLIOMA; HYBRID; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; FORSKOLIN; GLIOMA; HUMANS; HYBRID CELLS; MUTATION; NEUROBLASTOMA; RECEPTORS, ADRENERGIC, BETA-2; TRITIUM;

EID: 0031975592     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701600     Document Type: Article

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