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Volumn 10, Issue 4, 1998, Pages 279-294

The role of homeobox genes in hematopoiesis

Author keywords

Hematopoiesis; Homeobox genes; Stem cells leukemia; Transcription factors; Transgenic mice

Indexed keywords

HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR;

EID: 0031946319     PISSN: 0921299X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02678548     Document Type: Article
Times cited : (12)

References (126)
  • 2
    • 0024364615 scopus 로고    scopus 로고
    • Tamkum JK, Hartzell GW. The structure and function of the homeodomain.
    • Scott MF, Tamkum JK, Hartzell GW. The structure and function of the homeodomain. BBA 1989; 989: 25-48.
    • BBA 1989; 989: 25-48.
    • Scott, M.F.1
  • 3
    • 0028103855 scopus 로고    scopus 로고
    • Qiu Quian Y, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G, Wuthrich K. Homeodomain-DNA recognition.
    • Gehring W, Qiu Quian Y, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G, Wuthrich K. Homeodomain-DNA recognition. Cell 1994; 78:211-23.
    • Cell 1994; 78:211-23.
    • Gehring, W.1
  • 4
    • 0018240421 scopus 로고    scopus 로고
    • A gene complex controlling segmentation in Drosophila.
    • Lewis EB. A gene complex controlling segmentation in Drosophila. Nature 1978; 276: 565-70.
    • Nature 1978; 276: 565-70.
    • Lewis, E.B.1
  • 5
    • 0021717658 scopus 로고    scopus 로고
    • Rubin GM, Tjian R. Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila.
    • Levine M, Rubin GM, Tjian R. Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. Cell 1984; 38: 667-73.
    • Cell 1984; 38: 667-73.
    • Levine, M.1
  • 6
    • 0024592814 scopus 로고    scopus 로고
    • Hox and HOM: homologous gene clusters in insects and vertebrates.
    • Akam M. Hox and HOM: homologous gene clusters in insects and vertebrates. Cell 1989; 57: 347-9.
    • Cell 1989; 57: 347-9.
    • Akam, M.1
  • 7
    • 0024822383 scopus 로고    scopus 로고
    • D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncmelli E. The human HOX gene family.
    • Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncmelli E. The human HOX gene family. Nucl Acids Res 1989; 17: 10385-402.
    • Nucl Acids Res 1989; 17: 10385-402.
    • Acampora, D.1
  • 8
    • 0024341769 scopus 로고    scopus 로고
    • Dollé P. The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.
    • Duboule E, Dollé P. The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. Embo J 1989; 8: 1497-1505.
    • Embo J 1989; 8: 1497-1505.
    • Duboule, E.1
  • 9
    • 0024707103 scopus 로고    scopus 로고
    • Schugart K, Ruddle F. Two steps in the evolution of Antennapedia class vertebrate homeobox genes.
    • Kappen C, Schugart K, Ruddle F. Two steps in the evolution of Antennapedia class vertebrate homeobox genes. Proc Natl Acad Sei USA 1989; 86: 5459-63.
    • Proc Natl Acad Sei USA 1989; 86: 5459-63.
    • Kappen, C.1
  • 10
    • 0024589805 scopus 로고    scopus 로고
    • Papalopulu N, Krumlauf R. The murine and Drosophila homeobox clusters have common features of organization and expression.
    • Graham A, Papalopulu N, Krumlauf R. The murine and Drosophila homeobox clusters have common features of organization and expression. Cell 1989; 57: 367-78.
    • Cell 1989; 57: 367-78.
    • Graham, A.1
  • 11
    • 0026504525 scopus 로고    scopus 로고
    • Krumlauf R. Homeobox genes and axial patterning.
    • McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell 1992; 68: 283-302.
    • Cell 1992; 68: 283-302.
    • McGinnis, W.1
  • 12
    • 0028026651 scopus 로고    scopus 로고
    • Morata G. Homeobox genes: Their function in Drosophila segmentation and pattern formation.
    • Lawrence PA, Morata G. Homeobox genes: Their function in Drosophila segmentation and pattern formation. Cell 1994; 78: 181-9.
    • Cell 1994; 78: 181-9.
    • Lawrence, P.A.1
  • 13
    • 0030604724 scopus 로고    scopus 로고
    • Zakany J, Duboule D. Gene transpositions in the HOXD complex reveal a hierarchy of regulatory controls.
    • Van der Hoven F, Zakany J, Duboule D. Gene transpositions in the HOXD complex reveal a hierarchy of regulatory controls. Cell 1996; 85: 1025-35.
    • Cell 1996; 85: 1025-35.
    • Van Der Hoven, F.1
  • 15
    • 0026768070 scopus 로고    scopus 로고
    • Featherstone MS. An autoregulatory element of the murine HOX-4.2 gene.
    • Popped H, Featherstone MS. An autoregulatory element of the murine HOX-4.2 gene. EMBO J 1992; 11: 3673-80.
    • EMBO J 1992; 11: 3673-80.
    • Popped, H.1
  • 16
    • 0026529048 scopus 로고    scopus 로고
    • Simeone A, Guazzi S, Zappavigna V, Boncinelli E, Mavilio F. The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins.
    • Arcioni L, Simeone A, Guazzi S, Zappavigna V, Boncinelli E, Mavilio F. The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins. EMBO J 1992; 11: 265-77.
    • EMBO J 1992; 11: 265-77.
    • Arcioni, L.1
  • 17
    • 0029055810 scopus 로고    scopus 로고
    • Bienz M, Studer M, Chan SK, Aparicio S, Brenner S, Mann RS, Krumlauf R. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.
    • Popperl H, Bienz M, Studer M, Chan SK, Aparicio S, Brenner S, Mann RS, Krumlauf R. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 1995; 81: 1031-42.
    • Cell 1995; 81: 1031-42.
    • Popperl, H.1
  • 19
    • 0029160486 scopus 로고    scopus 로고
    • Guenther B, Desplan C, Kuriyan J. High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA.
    • Wilson DS, Guenther B, Desplan C, Kuriyan J. High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. Cell 1995; 82: 709-19.
    • Cell 1995; 82: 709-19.
    • Wilson, D.S.1
  • 21
    • 0027409040 scopus 로고    scopus 로고
    • Regulation of vertebrate homeobox-containing genes by morphogens.
    • Mavilio F. Regulation of vertebrate homeobox-containing genes by morphogens. Eur J Biochem 1993; 212: 273-88.
    • Eur J Biochem 1993; 212: 273-88.
    • Mavilio, F.1
  • 22
    • 0026485281 scopus 로고    scopus 로고
    • Largman C. Homeobox genes in normal hematopoiesis and leukemia.
    • Lawrence HJ, Largman C. Homeobox genes in normal hematopoiesis and leukemia. Blood 1992; 80: 2445-53.
    • Blood 1992; 80: 2445-53.
    • Lawrence, H.J.1
  • 23
    • 0029954818 scopus 로고    scopus 로고
    • Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis.
    • Lawrence HJ, Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells 1996; 14: 281-91.
    • Stem Cells 1996; 14: 281-91.
    • Lawrence, H.J.1
  • 24
    • 0030729371 scopus 로고    scopus 로고
    • Largman C, Lawrence HJ. Effects of HOX homeobox genes in blood cell differentiation.
    • Magli MC, Largman C, Lawrence HJ. Effects of HOX homeobox genes in blood cell differentiation. J Cell Physiol 1997; 173: 168-77.
    • J Cell Physiol 1997; 173: 168-77.
    • Magli, M.C.1
  • 25
    • 0025858183 scopus 로고    scopus 로고
    • Barba P, Celetti A, De Vita G, Cillo C, Boncinelli E. Coordinate regulation of HOX genes in human hematopoietic cells.
    • Magli MC, Barba P, Celetti A, De Vita G, Cillo C, Boncinelli E. Coordinate regulation of HOX genes in human hematopoietic cells. Proc Natl Acad Sei USA 1991; 88: 6348-52.
    • Proc Natl Acad Sei USA 1991; 88: 6348-52.
    • Magli, M.C.1
  • 26
    • 85176637662 scopus 로고    scopus 로고
    • Landsorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS, Largman C, Lawrence HJ, Humpries RK. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.
    • Sauvageau G, Landsorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS, Largman C, Lawrence HJ, Humpries RK. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sei USA 1994; 91: 12223-7.
    • Proc Natl Acad Sei USA 1994; 91: 12223-7.
    • Sauvageau, G.1
  • 27
    • 0025980567 scopus 로고    scopus 로고
    • Acampora D, Nigro V, Faiella A, D'Esposito M, Stornaiuolo A, Mavilio F, Boncinelli E. Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells.
    • Simeone A, Acampora D, Nigro V, Faiella A, D'Esposito M, Stornaiuolo A, Mavilio F, Boncinelli E. Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells. Mech Oev 1991; 33: 215-28.
    • Mech Oev 1991; 33: 215-28.
    • Simeone, A.1
  • 28
    • 0025003482 scopus 로고    scopus 로고
    • Acampora D, Arcioni A, Andrews P, Boncinelli E, Mavilio F. Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells.
    • Simeone A, Acampora D, Arcioni A, Andrews P, Boncinelli E, Mavilio F. Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells. Nature 1990; 346: 763-76.
    • Nature 1990; 346: 763-76.
    • Simeone, A.1
  • 30
    • 0029066642 scopus 로고    scopus 로고
    • Komatsu N, Moriuchi T. Overexpression of the HOX4A (HOXD3) homeobox gene in human erytroleukemia HEL cells results in altered adhesive properties.
    • Taniguchi Y, Komatsu N, Moriuchi T. Overexpression of the HOX4A (HOXD3) homeobox gene in human erytroleukemia HEL cells results in altered adhesive properties. Blood 1995; 10: 2786-94.
    • Blood 1995; 10: 2786-94.
    • Taniguchi, Y.1
  • 31
    • 0028883628 scopus 로고    scopus 로고
    • Sauvageau G, Ahmadi N, Lopez AR, LeBeau MM, Link M, Humphries K, Largman C. Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells.
    • Lawrence HJ, Sauvageau G, Ahmadi N, Lopez AR, LeBeau MM, Link M, Humphries K, Largman C. Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. Exp Hematol 1995; 23: 1160-6.
    • Exp Hematol 1995; 23: 1160-6.
    • Lawrence, H.J.1
  • 32
    • 0031031880 scopus 로고    scopus 로고
    • Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.
    • Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol 1997; 17:495-505.
    • Mol Cell Biol 1997; 17:495-505.
    • Thorsteinsdottir, U.1
  • 33
    • 85036686126 scopus 로고    scopus 로고
    • Benson GV, Rhoades KL, Maas RL, Tenen DG. HOXA10 deficient mice exhibit increased myelopoiesis and overproliferation of myeloid colony forming units.
    • Zhang P, Benson GV, Rhoades KL, Maas RL, Tenen DG. HOXA10 deficient mice exhibit increased myelopoiesis and overproliferation of myeloid colony forming units. Blood 1996; 88: 631a.
    • Blood 1996; 88: 631a.
    • Zhang, P.1
  • 34
    • 0025029192 scopus 로고    scopus 로고
    • Kongsuwan K, Visvader J, Adams JM, Cory S. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.
    • Perkins A, Kongsuwan K, Visvader J, Adams JM, Cory S. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc Natl Acad Sei USA 1990; 87: 8393-402.
    • Proc Natl Acad Sei USA 1990; 87: 8393-402.
    • Perkins, A.1
  • 35
    • 0027180437 scopus 로고    scopus 로고
    • Cory S. Conditional immortalization of mouse myelomonocytic megacaryocytic and mast cell progenitors by the HOX-2.4 homeobox gene.
    • Perkins A, Cory S. Conditional immortalization of mouse myelomonocytic megacaryocytic and mast cell progenitors by the HOX-2.4 homeobox gene. EMBO J 1993; 12: 383546.
    • EMBO J 1993; 12: 383546.
    • Perkins, A.1
  • 36
    • 0030891058 scopus 로고    scopus 로고
    • Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation.
    • Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. Immunity 1997; 6: 13-22.
    • Immunity 1997; 6: 13-22.
    • Sauvageau, G.1
  • 37
    • 0029091845 scopus 로고    scopus 로고
    • Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Landsorp PM, Humpries RK. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.
    • Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Landsorp PM, Humpries RK. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev 1995; 9: 1753-64.
    • Genes Dev 1995; 9: 1753-64.
    • Sauvageau, G.1
  • 38
    • 0029947439 scopus 로고    scopus 로고
    • Sauvageau G, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro.
    • Helgason CD, Sauvageau G, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. Blood 1996; 87: 2740-9.
    • Blood 1996; 87: 2740-9.
    • Helgason, C.D.1
  • 39
    • 0030942488 scopus 로고    scopus 로고
    • Helgason CD, Sauvageau G, Fong ST, Izon DJ, Humphries RK, Largman C. Mice bearing a targeted disruption of the homeobox HOXA9 have defects in myeloid, erythroid and lymphoid hematopoiesis.
    • Lawrence HJ, Helgason CD, Sauvageau G, Fong ST, Izon DJ, Humphries RK, Largman C. Mice bearing a targeted disruption of the homeobox HOXA9 have defects in myeloid, erythroid and lymphoid hematopoiesis. Blood 1997, 89: 1922-30.
    • Blood 1997, 89: 1922-30.
    • Lawrence, H.J.1
  • 40
    • 9044241254 scopus 로고    scopus 로고
    • Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K, Chen SJ, William CL, Chen IM, Feinberg AP, Jenkins NA, Copeland NG, Shaughnessy JD Jr. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;ll)(pl5;pl5) in human myeloid leukaemia.
    • Nakamura T, Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K, Chen SJ, William CL, Chen IM, Feinberg AP, Jenkins NA, Copeland NG, Shaughnessy JD Jr. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;ll)(pl5;pl5) in human myeloid leukaemia. Nature Genet 1996; 12: 154-8.
    • Nature Genet 1996; 12: 154-8.
    • Nakamura, T.1
  • 41
    • 9044249724 scopus 로고    scopus 로고
    • Shearman AM, Stanton VP Jr, Becher R, Collins T, Williams AJ, Dubé I, Katz F, Kwong YL, Morris C, Ohyashiki K, Toyama K, Rowley J, Housman DE. The t(7;ll)(pl5;pl5) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9.
    • Borrow J, Shearman AM, Stanton VP Jr, Becher R, Collins T, Williams AJ, Dubé I, Katz F, Kwong YL, Morris C, Ohyashiki K, Toyama K, Rowley J, Housman DE. The t(7;ll)(pl5;pl5) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9. Nature Genet 1996; 12: 159-67.
    • Nature Genet 1996; 12: 159-67.
    • Borrow, J.1
  • 42
    • 0030945893 scopus 로고    scopus 로고
    • Magnuson T. Murine Polycomb- and trithorax-gioup genes regulate homeotic pathways and beyond.
    • Schumacher A, Magnuson T. Murine Polycomb- and trithorax-gioup genes regulate homeotic pathways and beyond. TIG 1997; 13: 167-70.
    • TIG 1997; 13: 167-70.
    • Schumacher, A.1
  • 43
    • 0025833975 scopus 로고    scopus 로고
    • McCabe NR, Gill HJ, Espinosa R III, Patel J,Harden A, Rubinelli P, Smith SD, LeBeau MM, Rowley JD, Diaz MO. Identification of a gene, MLL, that spans the breakpoint in 1 Iq23 translocations associated with human leukemias.
    • Ziemin-van der Poel S, McCabe NR, Gill HJ, Espinosa R III, Patel J,Harden A, Rubinelli P, Smith SD, LeBeau MM, Rowley JD, Diaz MO. Identification of a gene, MLL, that spans the breakpoint in 1 Iq23 translocations associated with human leukemias. Proc Natl Acad Sei USA 1991; 88: 10735-9.
    • Proc Natl Acad Sei USA 1991; 88: 10735-9.
    • Ziemin-van Der Poel, S.1
  • 44
    • 0026454451 scopus 로고    scopus 로고
    • Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by Ilq23 chromosomal translocations in acute leukemias.
    • Tkachuk DC, Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by Ilq23 chromosomal translocations in acute leukemias. Cell 1992; 71: 691-700.
    • Cell 1992; 71: 691-700.
    • Tkachuk, D.C.1
  • 45
    • 0026496887 scopus 로고    scopus 로고
    • Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E. The t(4;ll) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.
    • Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E. The t(4;ll) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 1992; 71: 701-8.
    • Cell 1992; 71: 701-8.
    • Gu, Y.1
  • 46
    • 0030954681 scopus 로고    scopus 로고
    • Yu BD, Li B, Hanson R, Korsmeyer SJ. Defects in yolk sac hematopoiesis in Mil-Null embryos.
    • Hess JL, Yu BD, Li B, Hanson R, Korsmeyer SJ. Defects in yolk sac hematopoiesis in Mil-Null embryos. Blood 1997; 90: 1799-806.
    • Blood 1997; 90: 1799-806.
    • Hess, J.L.1
  • 47
    • 0025137176 scopus 로고    scopus 로고
    • Murre C, Sun XH, Baltimore D. A new homeobox gene contributes the DNA binding domain of the t( 1 ; 19) translocation protein in Pre-B ALL.
    • Kamps MP, Murre C, Sun XH, Baltimore D. A new homeobox gene contributes the DNA binding domain of the t( 1 ; 19) translocation protein in Pre-B ALL. Cell 1990; 60: 547-55.
    • Cell 1990; 60: 547-55.
    • Kamps, M.P.1
  • 48
    • 0025064238 scopus 로고    scopus 로고
    • Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary MC. Chromosomal translocation t(l;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.
    • Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary MC. Chromosomal translocation t(l;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 1990; 60: 535-45.
    • Cell 1990; 60: 535-45.
    • Nourse, J.1
  • 49
    • 85177156225 scopus 로고    scopus 로고
    • Cleary ML. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(l;19) leukemias.
    • LeBrun DL, Cleary ML. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(l;19) leukemias. Oncogene 1994; 9:1641-7.
    • Oncogene 1994; 9:1641-7.
    • Lebrun, D.L.1
  • 50
    • 0028231938 scopus 로고    scopus 로고
    • Wright DD, Kamps MP. Fusion with E2A converts the Pbxl homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(l;19) translocation.
    • Lu Q, Wright DD, Kamps MP. Fusion with E2A converts the Pbxl homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(l;19) translocation. Mol Cell Biol 1994; 14: 393818.
    • Mol Cell Biol 1994; 14: 393818.
    • Lu, Q.1
  • 51
    • 0027176915 scopus 로고    scopus 로고
    • Voorhoeve PM, Murre C. Pbxl is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.
    • Van Dijk MA, Voorhoeve PM, Murre C. Pbxl is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc Natl Acad Sei USA 1993; 90: 6061-5.
    • Proc Natl Acad Sei USA 1993; 90: 6061-5.
    • Van Ma, D.1
  • 52
    • 0027434620 scopus 로고    scopus 로고
    • Baltimore D. E2A-Pbxl, the t(l;19) translocation protein of human Pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice.
    • Kamps MP, Baltimore D. E2A-Pbxl, the t(l;19) translocation protein of human Pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice. Mol Cell Biol 1993; 13: 351-7.
    • Mol Cell Biol 1993; 13: 351-7.
    • Kamps, M.P.1
  • 53
    • 0026066608 scopus 로고    scopus 로고
    • Galili N, Nourse J, Saltman D, Cleary ML. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.
    • Monica K, Galili N, Nourse J, Saltman D, Cleary ML. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Mol Cell Biol 1991 ; 11 : 6149-57.
    • Mol Cell Biol 1991 ; 11 : 6149-57.
    • Monica, K.1
  • 54
    • 0027519720 scopus 로고    scopus 로고
    • Peifer M, Wieschaus E. Extradenticle, a regulator of homeotic gene activity, is a homolog of the homeoboxcontaining human proto-oncogene pbxl.
    • Rauskolb C, Peifer M, Wieschaus E. Extradenticle, a regulator of homeotic gene activity, is a homolog of the homeoboxcontaining human proto-oncogene pbxl. Cell 1993; 74: 1101-12.
    • Cell 1993; 74: 1101-12.
    • Rauskolb, C.1
  • 55
    • 85036686198 scopus 로고    scopus 로고
    • Chan SK. Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins.
    • Mann RS, Chan SK. Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins. TIG 1996; 12:2
    • TIG 1996; 12:2
    • Mann, R.S.1
  • 56
    • 0028947525 scopus 로고    scopus 로고
    • Shen WF, Rozenfeld S, Lawrence HJ, Largman C, Cleary ML. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.
    • Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C, Cleary ML. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes & Dev 1995; 9: 663-74.
    • Genes & Dev 1995; 9: 663-74.
    • Chang, C.P.1
  • 57
    • 0029008293 scopus 로고    scopus 로고
    • Rambaldi I, Featherstone MS. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif.
    • Phelan ML, Rambaldi I, Featherstone MS. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol Cell Biol 1995; 15: 3989-97.
    • Mol Cell Biol 1995; 15: 3989-97.
    • Phelan, M.L.1
  • 59
    • 85177147867 scopus 로고    scopus 로고
    • Peltenburg LTC, Van Dijk MA, Murre C. The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbxl and Pbx2 proteins.
    • Neuteboom SCT, Peltenburg LTC, Van Dijk MA, Murre C. The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbxl and Pbx2 proteins. Proc Natl Acad Sei USA 1995, 92: 9166-70.
    • Proc Natl Acad Sei USA 1995, 92: 9166-70.
    • Sct, N.1
  • 60
    • 0030929326 scopus 로고    scopus 로고
    • Rozenfeld S, Lawrence HJ, Largman C. The AbdB-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx 1 a on a novel DNA target.
    • Shen WF, Rozenfeld S, Lawrence HJ, Largman C. The AbdB-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx 1 a on a novel DNA target. J Biol Chem 1997; 13: 8198-206.
    • J Biol Chem 1997; 13: 8198-206.
    • Shen, W.F.1
  • 61
    • 0031031879 scopus 로고    scopus 로고
    • De Vivo I, Cleary ML. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbxl is necessary and sufficient for oncogenesis.
    • Chang CP, De Vivo I, Cleary ML. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbxl is necessary and sufficient for oncogenesis. Mol Cell Biol 1997; 17: 81-8.
    • Mol Cell Biol 1997; 17: 81-8.
    • Chang, C.P.1
  • 62
    • 0030896837 scopus 로고    scopus 로고
    • Florence B, Vaessin H, McGinnis W. A model for extradenticle function as a switch that changes HOX proteins from repressers to activators.
    • Pinsonneault J, Florence B, Vaessin H, McGinnis W. A model for extradenticle function as a switch that changes HOX proteins from repressers to activators. EMBO J 1997; 16: 2032-42.
    • EMBO J 1997; 16: 2032-42.
    • Pinsonneault, J.1
  • 63
    • 0029819070 scopus 로고    scopus 로고
    • Jenkins NA, Copeland NG. Identification of a new family of Pbx-related homeobox genes.
    • Nakamura T, Jenkins NA, Copeland NG. Identification of a new family of Pbx-related homeobox genes. Oncogene 1996; 13: 2235-42.
    • Oncogene 1996; 13: 2235-42.
    • Nakamura, T.1
  • 64
    • 0021206564 scopus 로고    scopus 로고
    • Johnson DA, Jenkins NA, Copeland NG, Evans R. Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice.
    • Bedigian HG, Johnson DA, Jenkins NA, Copeland NG, Evans R.Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice. J Virol 1984; 51: 586-94.
    • J Virol 1984; 51: 586-94.
    • Bedigian, H.G.1
  • 65
    • 0029082385 scopus 로고    scopus 로고
    • Bullrich F, Huebner K, Daar IO, Buchberg AM. Meisl, a PBX 1-related homeobox gene involved in myeloid leukemia in BXH-2 mice.
    • Moskow JJ, Bullrich F, Huebner K, Daar IO, Buchberg AM. Meisl, a PBX 1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol Cell Biol 1995; 15: 5434-43.
    • Mol Cell Biol 1995; 15: 5434-43.
    • Moskow, J.J.1
  • 67
    • 0027332476 scopus 로고    scopus 로고
    • Sheng G, Lecuit T, Dostatni N, Desplan C. Cooperative dimerization of Paired class homeo domains on DNA.
    • Wilson DS, Sheng G, Lecuit T, Dostatni N, Desplan C. Cooperative dimerization of Paired class homeo domains on DNA. Genes Dev 1993; 7: 2120-34.
    • Genes Dev 1993; 7: 2120-34.
    • Wilson, D.S.1
  • 68
    • 0022904751 scopus 로고    scopus 로고
    • Burri M, Baumgartner S, Frigerio g, Noll M. Conservation of a large protein domain in the segmentation gene paired and in functionally related genes in Drosophila.
    • Bopp D, Burri M, Baumgartner S, Frigerio g, Noll M. Conservation of a large protein domain in the segmentation gene paired and in functionally related genes in Drosophila. Cell 1986; 47: 103319.
    • Cell 1986; 47: 103319.
    • Bopp, D.1
  • 69
    • 0025884198 scopus 로고    scopus 로고
    • Harris E, Desplan C. The Paired Box encodes a second DNA-binding domain in the Paired homeo domain protein.
    • Treisman J, Harris E, Desplan C. The Paired Box encodes a second DNA-binding domain in the Paired homeo domain protein. Genes Dev 1991; 5: 594-604.
    • Genes Dev 1991; 5: 594-604.
    • Treisman, J.1
  • 72
    • 0030069119 scopus 로고    scopus 로고
    • Eibel H, Neubuser A, Wilting J, Hoseki H, Balling R. Paxl is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
    • Wallin J, Eibel H, Neubuser A, Wilting J, Hoseki H, Balling R. Paxl is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development 1996; 122: 23-30.
    • Development 1996; 122: 23-30.
    • Wallin, J.1
  • 73
    • 0026698147 scopus 로고    scopus 로고
    • Dorfler P, Aguzzi A, Kozmik Z, Urbanek P, Maurer-Fogy I, Busslinger M. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
    • Adams B, Dorfler P, Aguzzi A, Kozmik Z, Urbanek P, Maurer-Fogy I, Busslinger M. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev 1992; 6: 1589-607.
    • Genes Dev 1992; 6: 1589-607.
    • Adams, B.1
  • 74
    • 0027997502 scopus 로고    scopus 로고
    • Wang ZQ, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP.
    • Urbanek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 1994; 79: 901-12.
    • Cell 1994; 79: 901-12.
    • Urbanek, P.1
  • 75
    • 0028196601 scopus 로고    scopus 로고
    • Neurath MF, Max EE, Strober W. The B cell-specific transcritpion factor BSAP regulates B cell proliferation.
    • Wakatsuki Y, Neurath MF, Max EE, Strober W. The B cell-specific transcritpion factor BSAP regulates B cell proliferation. J Exp Med 1994; 179: 1099-108.
    • J Exp Med 1994; 179: 1099-108.
    • Wakatsuki, Y.1
  • 76
    • 0031110468 scopus 로고    scopus 로고
    • Wakatsuki Y, Matsunaga Y, Kaneko S, Kosek H, Kita T. Overexpression of B cell-specific activator protein (BSAP/Pax-5) in a late B cell is sufficient to suppress differentiation to an Ig high producer cell with plasma phenotype.
    • Usui T, Wakatsuki Y, Matsunaga Y, Kaneko S, Kosek H, Kita T. Overexpression of B cell-specific activator protein (BSAP/Pax-5) in a late B cell is sufficient to suppress differentiation to an Ig high producer cell with plasma phenotype. J Immun 1997; 158: 3197-204.
    • J Immun 1997; 158: 3197-204.
    • Usui, T.1
  • 77
    • 0027992622 scopus 로고    scopus 로고
    • Robanus Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC, Krop I, Schlissel MS, Feeney AJ, Van Roon M, Van Der Valk M, Te Riele HPJ, Berns A, Murre C. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangments.
    • Bain G, Robanus Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC, Krop I, Schlissel MS, Feeney AJ, Van Roon M, Van Der Valk M, Te Riele HPJ, Berns A, Murre C. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangments. Cell 1994; 79: 885-92.
    • Cell 1994; 79: 885-92.
    • Bain, G.1
  • 78
    • 0026710736 scopus 로고    scopus 로고
    • Wang S, Dorfler P, Adams B, Busslinger M. The promoter of the CD 19 gene is a target for the B cell-specific transcription factor BSAP.
    • Kozmik Z, Wang S, Dorfler P, Adams B, Busslinger M. The promoter of the CD 19 gene is a target for the B cell-specific transcription factor BSAP. Mol Cell Biol 1992; 12: 2662-72.
    • Mol Cell Biol 1992; 12: 2662-72.
    • Kozmik, Z.1
  • 79
    • 0028809870 scopus 로고    scopus 로고
    • Haffner R, Oren M, Grass P. Loss of p53 function through PAX-raediated transcriptional repression.
    • Stuart ET, Haffner R, Oren M, Grass P. Loss of p53 function through PAX-raediated transcriptional repression. EMBO J 1995; 14: 563815.
    • EMBO J 1995; 14: 563815.
    • Stuart, E.T.1
  • 80
    • 0029998350 scopus 로고    scopus 로고
    • Klix N, Pfeifer P, Graninger PG, Kozmik Z. Deregulation of PAX-5 by translocation of the E enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma.
    • Busslinger M, Klix N, Pfeifer P, Graninger PG, Kozmik Z. Deregulation of PAX-5 by translocation of the E enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma. Proc Nad Acad Sei USA 1996; 93: 6129-34.
    • Proc Nad Acad Sei USA 1996; 93: 6129-34.
    • Busslinger, M.1
  • 81
    • 10544241195 scopus 로고    scopus 로고
    • Rao PH, Nallasivam P, Hibshoosh H, Butler M, Louie DC, Dyomin V, Ohno H, Chaganti RSK, Dalla-Favera R. The t(9;14)(p!3;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene.
    • lida S, Rao PH, Nallasivam P, Hibshoosh H, Butler M, Louie DC, Dyomin V, Ohno H, Chaganti RSK, Dalla-Favera R. The t(9;14)(p!3;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene. Blood 1996; 88: 4110-17.
    • Blood 1996; 88: 4110-17.
  • 82
    • 0026453505 scopus 로고    scopus 로고
    • Parsa NZ, Filippa D, Jhanwar SC, Chaganti RSK.t(9;14)(pl3;q32) denotes a subset of low-grade non Hodgkin's lymphoma with plasmacytoid differentiation.
    • Offit K, Parsa NZ, Filippa D, Jhanwar SC, Chaganti RSK.t(9;14)(pl3;q32) denotes a subset of low-grade non Hodgkin's lymphoma with plasmacytoid differentiation. Blood 1992; 80: 2594-9.
    • Blood 1992; 80: 2594-9.
    • Offit, K.1
  • 83
    • 0024042904 scopus 로고    scopus 로고
    • Webb E, Housiaux P, Adams JM. Expression of multiple homeobox genes within diverse mammalian hematopoietic lineages.
    • Kongsuwan K, Webb E, Housiaux P, Adams JM. Expression of multiple homeobox genes within diverse mammalian hematopoietic lineages. EMBO J 1988; 7: 2131-8.
    • EMBO J 1988; 7: 2131-8.
    • Kongsuwan, K.1
  • 84
    • 0029740603 scopus 로고    scopus 로고
    • Brivanlou IH, Kelley CM, Zon LI. BMP-4responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.l.
    • Mead PE, Brivanlou IH, Kelley CM, Zon LI. BMP-4responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.l. Nature 1996, 382: 357-60.
    • Nature 1996, 382: 357-60.
    • Mead, P.E.1
  • 85
    • 0029820548 scopus 로고    scopus 로고
    • Mazan S, Avantaggiato V, Barone P, Tuorto F, Lallemand Y, Brulet P, Simeone A. Epilepsy and brain abnormalities in mice lacking the Otxl gene.
    • Acampora D, Mazan S, Avantaggiato V, Barone P, Tuorto F, Lallemand Y, Brulet P, Simeone A.Epilepsy and brain abnormalities in mice lacking the Otxl gene. Nature Genet 14: 218-22.
    • Nature Genet 14: 218-22.
    • Acampora, D.1
  • 86
    • 0027174566 scopus 로고    scopus 로고
    • Sanchez-Garcia I, Rabbitts TH. The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.
    • Dear TN, Sanchez-Garcia I, Rabbitts TH. The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes. Proc Natl Acad Sei 1993; 90: 4431-5.
    • Proc Natl Acad Sei 1993; 90: 4431-5.
    • Dear, T.N.1
  • 87
    • 0025894715 scopus 로고    scopus 로고
    • Roberts CW, Minden M, Crist WM, Korsmeyer SJ. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia.
    • Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 1991; 253: 79-82.
    • Science 1991; 253: 79-82.
    • Hatano, M.1
  • 88
    • 0026046616 scopus 로고    scopus 로고
    • Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH. HOX11, a homeoboxcontaining T-cell oncogene on human chromosome 10q24.
    • Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH. HOX11, a homeoboxcontaining T-cell oncogene on human chromosome 10q24. Proc Natl Acad Sei 1991; 88: 8900-04.
    • Proc Natl Acad Sei 1991; 88: 8900-04.
    • Ma, K.1
  • 89
    • 0025785081 scopus 로고    scopus 로고
    • Gong Z, Shen W, Ho AD. The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein.
    • Lu M, Gong Z, Shen W, Ho AD. The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein. EMBO J 1991; 10: 2905-10.
    • EMBO J 1991; 10: 2905-10.
    • Lu, M.1
  • 90
    • 0025748060 scopus 로고    scopus 로고
    • Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J, Baker JB. A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocations t(10;14).
    • Dube ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J, Baker JB. A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocations t(10;14). Blood 1991; 78: 2996-3003.
    • Blood 1991; 78: 2996-3003.
    • Dube, I.D.1
  • 91
    • 0029862814 scopus 로고    scopus 로고
    • Shen WF, Ho AD, Lu M. Three distinct domains in thé HOX-11 homeobox oncoprotein are required for optimal transactivation.
    • Zhang N, Shen WF, Ho AD, Lu M. Three distinct domains in thé HOX-11 homeobox oncoprotein are required for optimal transactivation. Oncogene 1996; 13:1781-7.
    • Oncogene 1996; 13:1781-7.
    • Zhang, N.1
  • 92
    • 0028948960 scopus 로고    scopus 로고
    • Shen WF, Ho AD, Lu M. Tyrosine phosphorylation is required for up-regulation of the HOX-ll(TCL-3) homeobox proto-oncogene in T cells.
    • Zhang N, Shen WF, Ho AD, Lu M. Tyrosine phosphorylation is required for up-regulation of the HOX-ll(TCL-3) homeobox proto-oncogene in T cells. Cancer Res 1995; 55: 1117-21.
    • Cancer Res 1995; 55: 1117-21.
    • Zhang, N.1
  • 93
    • 0027486021 scopus 로고    scopus 로고
    • Gong Z, Minden M, Lu M. The HOX-11(TCL3) homeobox proto-oncogene encodes a nuclear protein that undergoes cell cycle-dependent regulation.
    • Zhang N, Gong Z, Minden M, Lu M. The HOX-11(TCL3) homeobox proto-oncogene encodes a nuclear protein that undergoes cell cycle-dependent regulation. Oncogene 1993; 8: 3265-70.
    • Oncogene 1993; 8: 3265-70.
    • Zhang, N.1
  • 94
    • 0028335821 scopus 로고    scopus 로고
    • Shutter JR, Korsmeyer SJ. Hoxll controls the genesis of the spleen.
    • Roberts CWM, Shutter JR, Korsmeyer SJ. Hoxll controls the genesis of the spleen. Nature 1994; 368:747-9.
    • Nature 1994; 368:747-9.
    • Cwm, R.1
  • 95
    • 85177145793 scopus 로고    scopus 로고
    • Colledge WH, Carlton MBL, Lavenir I, Larson T, Smith AJH, Warren AJ, Evans MJ, Sofroniew MV, Rabbitts TH. The Hoxll gene is essential for cell survival during spleen development.
    • Dear TN, Colledge WH, Carlton MBL, Lavenir I, Larson T, Smith AJH, Warren AJ, Evans MJ, Sofroniew MV, Rabbitts TH. The Hoxll gene is essential for cell survival during spleen development. Development 1995; 121: 2909-15.
    • Development 1995; 121: 2909-15.
    • Dear, T.N.1
  • 96
    • 0028155997 scopus 로고    scopus 로고
    • Fong AZC, Lu M, Hawley TS. The HOX11 homeobox-containing gene of human leukemia immortalizes murine hematopoietic precursors.
    • Hawley RG, Fong AZC, Lu M, Hawley TS. The HOX11 homeobox-containing gene of human leukemia immortalizes murine hematopoietic precursors. Oncogene 1994; 9: 1-12.
    • Oncogene 1994; 9: 1-12.
    • Hawley, R.G.1
  • 97
    • 0031014272 scopus 로고    scopus 로고
    • Fong AZC, Reis MD, Zhang N, Lu M, Hawley TS. Transforming function of the HOX11/TCL3 homeobox gene.
    • Hawley RG, Fong AZC, Reis MD, Zhang N, Lu M, Hawley TS. Transforming function of the HOX11/TCL3 homeobox gene. Cancer Res 1997; 57: 3375.
    • Cancer Res 1997; 57: 3375.
    • Hawley, R.G.1
  • 98
    • 0031031397 scopus 로고    scopus 로고
    • Muslin AJ, Korsmeyer SJ. HOX11 interacts with protein phospatases PP2A and PP1 and disrupts a G2/M cellcycle checkpoint.
    • Kawabe T, Muslin AJ, Korsmeyer SJ. HOX11 interacts with protein phospatases PP2A and PP1 and disrupts a G2/M cellcycle checkpoint. Nature 1997; 385: 454-8.
    • Nature 1997; 385: 454-8.
    • Kawabe, T.1
  • 99
    • 0025911365 scopus 로고    scopus 로고
    • Lints T, Lenkins NA, Copeland NG, Stresser A, Harvey RP, Adams JM. Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis.
    • Alien JD, Lints T, Lenkins NA, Copeland NG, Stresser A, Harvey RP, Adams JM. Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis. Genes & Dev 1991; 5: 509-20.
    • Genes & Dev 1991; 5: 509-20.
    • Alien, J.D.1
  • 100
    • 0027194128 scopus 로고    scopus 로고
    • Adams JM. Enforced expression of Hlx homeobox gene prompts myeloid cell maturation and altered adherence properties of T cells.
    • Alien JD, Adams JM. Enforced expression of Hlx homeobox gene prompts myeloid cell maturation and altered adherence properties of T cells. Blood 1993; 12: 3242-51.
    • Blood 1993; 12: 3242-51.
    • Alien, J.D.1
  • 101
    • 85177015849 scopus 로고    scopus 로고
    • Harris AW, Bath ML, Stresser A, Scollay R, Adams JM. Perturbed development of T and B cells in mice expressing an Hlx homeobox transgene.
    • Alien JD, Harris AW, Bath ML, Stresser A, Scollay R, Adams JM. Perturbed development of T and B cells in mice expressing an Hlx homeobox transgene. J Immunology 1995; 154: 1531-42.
    • J Immunology 1995; 154: 1531-42.
    • Alien, J.D.1
  • 102
    • 0030046511 scopus 로고    scopus 로고
    • Lyons I, Li R, Hartley L, Lints TJ, Adams JM, Harvey RP. Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut.
    • Hentsch B, Lyons I, Li R, Hartley L, Lints TJ, Adams JM, Harvey RP. Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut. Genes & Dev 1996; 10: 70-9.
    • Genes & Dev 1996; 10: 70-9.
    • Hentsch, B.1
  • 103
    • 0025793872 scopus 로고    scopus 로고
    • Moroney JF, Wilson GL, Fox CH, Winter HS, Kehrl JH. Cloning and expression of a human homeobox gene which resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes.
    • Deguchi Y, Moroney JF, Wilson GL, Fox CH, Winter HS, Kehrl JH. Cloning and expression of a human homeobox gene which resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes. New Biologist 1991; 3: 353-63.
    • New Biologist 1991; 3: 353-63.
    • Deguchi, Y.1
  • 104
    • 0026630543 scopus 로고    scopus 로고
    • Thevenin C, Kehrl JH. Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth.
    • Deguchi Y, Thevenin C, Kehrl JH. Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth. J Biol Chem 1992; 12: 8222-9.
    • J Biol Chem 1992; 12: 8222-9.
    • Deguchi, Y.1
  • 105
    • 0027405557 scopus 로고    scopus 로고
    • Agus D, Kehrl JH. A human homeobox gene, HB24, inhibits development of CD4+ cells and impairs thymic involution in transgenic mice.
    • Deguchi Y, Agus D, Kehrl JH. A human homeobox gene, HB24, inhibits development of CD4+ cells and impairs thymic involution in transgenic mice. J Biol Chem 1993; 268: 3646-53.
    • J Biol Chem 1993; 268: 3646-53.
    • Deguchi, Y.1
  • 106
    • 0025851448 scopus 로고    scopus 로고
    • Kehrl JH. Selective expression of two homeobox genes in CD34-positive cells from human bone marrow.
    • Deguchi Y, Kehrl JH. Selective expression of two homeobox genes in CD34-positive cells from human bone marrow. Blood 1991; 2: 323-8.
    • Blood 1991; 2: 323-8.
    • Deguchi, Y.1
  • 107
    • 0027413018 scopus 로고    scopus 로고
    • Yamanaka Y, Theodossiou C, Najfeld V, Kehrl JH. High expression of two diverged homeobox genes, HB24 and HB9, in acute leukemias: molecular markers of hematopoietic cell immaturity.
    • Deguchi Y, Yamanaka Y, Theodossiou C, Najfeld V, Kehrl JH. High expression of two diverged homeobox genes, HB24 and HB9, in acute leukemias: molecular markers of hematopoietic cell immaturity. Leukemia 1993; 7: 446-51.
    • Leukemia 1993; 7: 446-51.
    • Deguchi, Y.1
  • 108
    • 85177155792 scopus 로고    scopus 로고
    • Druey KM, Deguchi Y, Tuscano JM, Kehrl JH. A novel human homeobox gene distantly related toprobosci-pedia is expressed in lymphoid and pancreatic tissue.
    • Harrison KA, Druey KM, Deguchi Y, Tuscano JM, Kehrl JH. A novel human homeobox gene distantly related toprobosci-pedia is expressed in lymphoid and pancreatic tissue. J Biol Chem 1994, 269: 19968-75.
    • J Biol Chem 1994, 269: 19968-75.
    • Harrison, K.A.1
  • 109
    • 0026462854 scopus 로고    scopus 로고
    • Bartlett TJ, MacGregor AD, Manfloletti G, Buratti E, Giancotti V, Goodwin GH. Identification of a novel vertebrate homeobox gene expressed in hematopoietic cells.
    • Crompton MR, Bartlett TJ, MacGregor AD, Manfloletti G, Buratti E, Giancotti V, Goodwin GH. Identification of a novel vertebrate homeobox gene expressed in hematopoietic cells. Nucleic Acid Res 1992; 20: 5661-7.
    • Nucleic Acid Res 1992; 20: 5661-7.
    • Crompton, M.R.1
  • 110
    • 0027205023 scopus 로고    scopus 로고
    • Ashworth A, Enver T, Wiedemann LM. HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human.
    • Bedford FK, Ashworth A, Enver T, Wiedemann LM. HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human. Nucleic Acids Res 1993; 21: 1245-9.
    • Nucleic Acids Res 1993; 21: 1245-9.
    • Bedford, F.K.1
  • 111
    • 0028957954 scopus 로고    scopus 로고
    • Buratti E, Rustighi A, De IUliis A, Aldinucci D, Goodwin H, Pinto A. Differential expression of a novel proline-rich homeobox gene (Prh) in human hematolymphopoietic cells.
    • Manfioletti G, Buratti E, Rustighi A, De IUliis A, Aldinucci D, Goodwin H, Pinto A. Differential expression of a novel proline-rich homeobox gene (Prh) in human hematolymphopoietic cells. Blood 1995; 85: 1237-45.
    • Blood 1995; 85: 1237-45.
    • Manfioletti, G.1
  • 112
    • 0025886340 scopus 로고    scopus 로고
    • Octamania: the POU factors in murine development.
    • Scholer HR. Octamania: the POU factors in murine development. TIG 1991; 7: 323-9.
    • TIG 1991; 7: 323-9.
    • Scholer, H.R.1
  • 113
    • 0027193484 scopus 로고    scopus 로고
    • Healy LE, Copeland NG, Gilbert DJ, Jenkins NA, Willison KR, Ashworth A. Cloning, chromosomal localization and expression pattern of the POD domain gene Oct-11.
    • Goldsborough AS, Healy LE, Copeland NG, Gilbert DJ, Jenkins NA, Willison KR, Ashworth A. Cloning, chromosomal localization and expression pattern of the POD domain gene Oct-11. Nucleic Acids Res 1993; 21: 127-34.
    • Nucleic Acids Res 1993; 21: 127-34.
    • Goldsborough, A.S.1
  • 114
    • 0030006437 scopus 로고    scopus 로고
    • Leng C, Krappmann D, Emmerich F, Mapara MY, Bommert K, Royer HD, Scheidereit C, Dorken B. High-level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells.
    • Bargou RC, Leng C, Krappmann D, Emmerich F, Mapara MY, Bommert K, Royer HD, Scheidereit C, Dorken B. High-level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells. Blood 1996; 87: 4340-7.
    • Blood 1996; 87: 4340-7.
    • Bargou, R.C.1
  • 115
    • 0025282571 scopus 로고    scopus 로고
    • Pedersen S, Schreiber E, Matthias P. Extinction of an immunoglobulin kappa promoter in cell hybrids is mediated by the octamer motif and correlated with suppression of Oct-2 expression.
    • Junker S, Pedersen S, Schreiber E, Matthias P. Extinction of an immunoglobulin kappa promoter in cell hybrids is mediated by the octamer motif and correlated with suppression of Oct-2 expression. Cell 1990; 61: 467-74.
    • Cell 1990; 61: 467-74.
    • Junker, S.1
  • 116
    • 0027171744 scopus 로고    scopus 로고
    • Klug CA, Arvin KL, Singh H. Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation.
    • Feldhaus AL, Klug CA, Arvin KL, Singh H. Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation. EMBO J 1993; 12: 2763-72.
    • EMBO J 1993; 12: 2763-72.
    • Feldhaus, A.L.1
  • 117
    • 0027262608 scopus 로고    scopus 로고
    • Karvelas M, Nossal GJV, Ye ZS, Jacks T. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival.
    • Corcoran LM, Karvelas M, Nossal GJV, Ye ZS, Jacks T. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival. Genes & Dev 1993; 7: 570-82.
    • Genes & Dev 1993; 7: 570-82.
    • Corcoran, L.M.1
  • 118
    • 0027397909 scopus 로고    scopus 로고
    • Baldassare M, Fisher P, Rathbun G, Oltz EM, Yancopoulos GD, Jessell TM, Alt FW. LH-2: A LIM/homeodomain gene expressed in developing lymphocytes and neural cells.
    • Xu Y, Baldassare M, Fisher P, Rathbun G, Oltz EM, Yancopoulos GD, Jessell TM, Alt FW. LH-2: A LIM/homeodomain gene expressed in developing lymphocytes and neural cells. Proc Natl Acad Sei USA 1993; 90: 227-31.
    • Proc Natl Acad Sei USA 1993; 90: 227-31.
    • Xu, Y.1
  • 119
    • 0029932297 scopus 로고    scopus 로고
    • Heng HHQ, Siderovski DP, Dong WF, Okuno Y, Shi XM, Tsui LC, Minden MD. Identification of a human LIMHox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1.
    • Wu HK, Heng HHQ, Siderovski DP, Dong WF, Okuno Y, Shi XM, Tsui LC, Minden MD. Identification of a human LIMHox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1. Oncogene 1996; 12: 1205-12.
    • Oncogene 1996; 12: 1205-12.
    • Wu, H.K.1
  • 120
    • 0023669230 scopus 로고    scopus 로고
    • Superti-Furga G, Busslinger M. Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter.
    • Barberis A, Superti-Furga G, Busslinger M. Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter. Cell 1987; 50: 347-59.
    • Cell 1987; 50: 347-59.
    • Barberis, A.1
  • 121
    • 0030963502 scopus 로고    scopus 로고
    • Tarnasky HA, Valarché I, Nepveu A, Van Der Hoorn FA. Cux/CDP homeodomain protein binds to an enhancer in the rat c-mos locus and represses its activity.
    • Higgy NA, Tarnasky HA, Valarché I, Nepveu A, Van Der Hoorn FA. Cux/CDP homeodomain protein binds to an enhancer in the rat c-mos locus and represses its activity. BBA 1997; 1351: 313-24.
    • BBA 1997; 1351: 313-24.
    • Higgy, N.A.1
  • 122
    • 85177012431 scopus 로고    scopus 로고
    • Donady JJ, Tufarelli C, Neufelds EJ. Represser activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
    • Lievens PMJ, Donady JJ, Tufarelli C, Neufelds EJ. Represser activity of CCAAT displacement protein in HL-60 myeloid leukemia cells. J Biol Chem 1995; 270: 12745-50.
    • J Biol Chem 1995; 270: 12745-50.
    • Pmj, L.1
  • 123
    • 0030990447 scopus 로고    scopus 로고
    • Nakamura S, Bollekens J, Ruddle FH, Takeshita K. Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis.
    • Shimamoto T, Nakamura S, Bollekens J, Ruddle FH, Takeshita K. Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis. Proc Natl Acad Sei 1997; 94: 3245-9.
    • Proc Natl Acad Sei 1997; 94: 3245-9.
    • Shimamoto, T.1
  • 124
    • 0023673201 scopus 로고    scopus 로고
    • Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b is mediated by the H2b subtype-specific consensus element.
    • LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b is mediated by the H2b subtype-specific consensus element. Genes & Dev 1988; 2: 32-9.
    • Genes & Dev 1988; 2: 32-9.
    • Labella, F.1
  • 125
    • 0029859407 scopus 로고    scopus 로고
    • Van Gurp MF, De Ridder MC, Tufarelli C, Last TJ, Birnbaum M, Vaughan PS, Giordano A, Krek W, Neufeld ET, Stein JL, Stein OS. CDP:cut is the DNAbinding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the Gj/S phase cell cycle transition point independent of transcription factor E2F.
    • Van Wijnen AJ, Van Gurp MF, De Ridder MC, Tufarelli C, Last TJ, Birnbaum M, Vaughan PS, Giordano A, Krek W, Neufeld ET, Stein JL, Stein OS. CDP:cut is the DNAbinding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the Gj/S phase cell cycle transition point independent of transcription factor E2F. Proc Natl Acad Sei USA 1996; 93: 11516-21.
    • Proc Natl Acad Sei USA 1996; 93: 11516-21.
    • Van Wijnen, A.J.1
  • 126
    • 0029744104 scopus 로고    scopus 로고
    • Asoh S, Nirenberg M. Cloning and characterization of four murine homeobox genes.
    • Rovescalli AC, Asoh S, Nirenberg M. Cloning and characterization of four murine homeobox genes. Proc Natl Acad Sei 1996; 93: 10691-6.
    • Proc Natl Acad Sei 1996; 93: 10691-6.
    • Rovescalli, A.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.