Homeobox genes: Their function in Drosophila segmentation and pattern formation

Cell

Volumn 78, Issue 2, 1994, Pages 181-189

  Lawrence, Peter A ^a   Morata, Gines ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; DNA BINDING; DROSOPHILA; GENE CLUSTER; GENE EXPRESSION; GENE TARGETING; GENETIC LINKAGE; GENETIC SELECTION; GENETIC TRANSFORMATION; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVIEW;

EID: 0028026651     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(94)90289-5     Document Type: Review

References (72)

1. tinman and bagpipe: two homeobox genes that determine cell fates in the dorsal mesoderm of Drosophila
2. Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes
3. Compartment boundaries and the control of Drosophila limb pattern by the hedgehog protein
4. Mechanisms of compartment formation: evidence that non-proliferating cells do not play a critical role in defining the D/V lineage restriction in the developing wing of Drosophila
5. Control of morphogenesis and differentiation by HOM/Hox genes
6. trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each
7. The 412 transposon and the development of gonadal mesoderm in Drosophila
8. Ectopic expression of homeotic genes caused by the elimination of the Polycomb gene in Drosophila imaginal epidermis
9. Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis
10. Specification of limb development in the Drosophila embryo by positional cues from segmentation genes
11. Drosophila headlines
12. Compartments and polyclones in Drosophila development
13. The Drosophila developmental gene engrailed encodes a sequence specific DNA binding activity
14. Interaction between dorsal and ventral cells in the imaginal disc direct wing development in Drosophila
15. Patterning in the vertebrate limb
16. The bithorax complex
17. Pattern reconstruction by dissociated imaginal disc cells of Drosophila melanogaster
18. Genetic control of wing disk development in Drosophila
19. Developmental compartmentalization of the wing disc of Drosophila
20. Compartments in animal development
21. Head and thoracic transformations caused by ectopic expression of Antennapedia during Drosophila development
22. The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products
23. Targets of homeotic gene control in Drosophila
24. Regulation of Antennapedia transcripts by the bithorax complex of Drosophila
25. Divergent homeo box proteins recognize similar DNA sequences in Drosophila
26. Specification of a single cell type by a Drosophila homeotic gene
27. Induction across germ layers in Drosophila mediated by a genetic cascade
28. A clonal analysis of the requirement for the trithorax gene in the diversification of segments in Drosophila
29. The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function
30. A group of genes controlling spatial expression of the bithorax complex of Drosophila
31. The genetic regulation of segmentation in Drosophila melanogaster
32. Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster
33. A clonal analysis of segment development in Oncopeltus (Hemiptera)
34. Compartments in the wing disc of Drosophila: a study with the engrailed gene
35. Different requirements for homeotic genes in the soma and germ line of Drosophila
36. Homeobox proteins as sequence specific transcription factors
37. Genes and developmental pathways
38. A gene complex controlling segmentation in Drosophila
39. Functional dissection of Ultrabithorax proteins in Drosophila melanogaster
40. Parasegments and compartments in the Drosophila embryo
41. Homeobox genes and axial patterning
42. A conserved DNA sequence in homeotic genes of the Drosophila Antennapedia and bithorax complexes
43. Cell lineage of larval and imaginal thoracic anlagen cells of Drosophila melanogaster, as revealed by single cell transplantations
44. Developmental analysis of some mutants of the bithorax system of Drosophila
45. Homeotic genes, compartments and cell determination in Drosophila
46. Sharp anterior boundary of homeotic gene expression conferred by the fushi tarazu protein
47. Determination of the embryonic axes of Drosophila
48. A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β gene family
49. A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis
50. Imprinting a determined state into the chromatin of Drosophila
51. Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity
52. A role of Polycomb group genes in the regulation of gap gene expression in Drosophila
53. The gene serpent has homeotic properties and specifies endoderm versus ectoderm within the Drosophila gut
54. Sonic hedgehog mediates the polarizing activity of the ZPA
55. The role of teashirt in trunk segmental identity in Drosophila
56. Drosophila development after the first three hours
57. Genetic organization of Drosophila bithorax complex
58. Direct homeodomain-DNA interaction in the regulation of the fushi tarazu gene
59. Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax and fushi tarazu loci of Drosophila
60. Genes controlling segmental specification in the Drosophila thorax
61. + gene in ensuring the selective expression of segment specific homeotic genes in Drosophila
62. Splitting the bithorax complex of Drosophila
63. Regulation of the Ultrabithorax gene by other bithorax complex genes
64. Control of Drosophila body pattern by the hunchback morphogen gradient
65. Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
66. brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SW12
67. Drosophila homeotic genes encode transcriptional activators similar to OTF-2
68. Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling
69. The state of engrailed expression is not clonally transmitted during early Drosophila development
70. Identification of target genes of the homeotic gene Antennapedia by enhancer detection
71. Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions