extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1

Cell

Volumn 74, Issue 6, 1993, Pages 1101-1112

  Rauskolb, Cordella ^a   Peifer, Mark ^a   Wieschaus, Eric ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; DNA RECOMBINATION; DNA SEQUENCE; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION; GENE MAPPING; GENE MUTATION; GENETIC TRANSFORMATION; HOMEOBOX; IN SITU HYBRIDIZATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTO ONCOGENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CLONING, MOLECULAR; COMPARATIVE STUDY; DNA-BINDING PROTEINS; DROSOPHILA; GENES, HOMEOBOX; GENES, REGULATOR; HOMINIDAE; HUMAN; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENES; RECOMBINATION, GENETIC; RESTRICTION MAPPING; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0027519720     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(93)90731-5     Document Type: Article

References (87)

1. Downstream of the homeotic genes
2. Codon usage tabulated from the GenBank sequence data
3. The sequence of the DNAs coding for the mating-type loci of Saccharomyces cerevisiae
4. Segmental distribution of bithorax complex proteins during Drosophila development
5. An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters
6. Molecular definition of the morphogenetic and regulatory functions and the cis-regulatory elements of the Drosophila Abd-B homeotic gene
7. Functional cDNA libraries from Drosophila embryos
8. Temporal and spatial relationships between segmentation and homeotic gene expression in Drosophila embryos: distributions of the fushi tarazu, engrailed, Sex combs reduced, Antennapedia, and Ultrabithorax proteins
9. Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates
10. The molecular genetics of the bithorax complex of Drosophila: characterization of the products of the Abdominal-B domain
11. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeo box gene Hox-1.5
12. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila
13. Expression of Abdominal-B homeoproteins in Drosophila embryos
14. The sequence specificity of homeodomain-DNA interaction
15. Binding of yeast a1 and α2 as a heterodimer to the operator DNA of a haploid-specific gene
16. The structural and functional organization of the murine HOX gene family resembles that of Drosophila. homeotic genes
17. The bithorax complex
18. The homeo domain of a murine protein binds 5′ to its own homeo box
19. The characterization of chromosome breaks in Drosophila melanogaster. I. Mass isolation of deficiencies which have an end point in the 14A-15A region
20. Molecular phylogeny of the animal kingdom
21. Dpbx, a new homeobox gene closely related to the human proto-oncogene pbx1
22. Genetic control of wing disc development in Drosophila
23. Head and thoracic transformation caused by ectopic expression of Antennapedia during Drosophila development
24. The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products
25. Targets of homeotic gene control in Drosophila
26. a1 protein alters the DNA binding specificity of α2 repressor
27. The murine and Drosophila homeobox gene complexes have common features of organization and expression
28. What determines the specificity of action of Drosophila homeodomain proteins?
29. Divergent homeobox proteins recognize similar DNA sequences in Drosophila
30. Induction across germ layers in Drosophila mediated by a genetic cascade
31. The large upstream control region of the Drosophila homeotic gene Ultrabithorax
32. A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast
33. Stimulation of transcription by an Ultrabithorax protein in vitro
34. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
35. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials
36. abdA expression in Drosophila embryos
37. Proto-oncogenes in Drosophila: molecular and genetic analysis
38. Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster
39. In vitro binding to the leucine tRNA gene identifies a novel yeast homeobox gene
40. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: a framework for understanding homeodomain-DNA interactions
41. Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells
42. Evolution of the vertebrate Hox homeobox genes
43. Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization
44. Ectopic expression of UBX and ABD-B proteins during Drosophila embryogenesis: competition, not functional hierarchy, explains phenotypic suppression
45. Homeobox genes in normal hematopoiesis and leukemia
46. Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene
47. Homeobox proteins as sequence-specific transcription factors
48. A gene complex controlling segmentation in Drosophila
49. Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression
50. Expression and regulation of the abd-A gene of Drosophila
51. Novel patterns of homeotic protein accumulation in the head of the Drosophila embryo
52. Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae
53. The isolation of structural genes from libraries of eucaryotic DNA
54. Functional dissection of Ultrabithorax proteins in D. melanogaster
55. The interactions of transcription factors and their adaptors, coactivators and accessory proteins
56. Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in Drosophila embryos and larvae
57. Homeobox genes and axial patterning
58. A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans
59. A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes
60. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1
61. Isolation and sequence-specific DNA binding of the Antennapedia homeodomain
62. Cis acting DNA sequence requirements for P element transposition
63. Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
64. The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein
65. Improved tools for biological sequence comparison
66. Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity
67. Vectors for P-mediated transformations in Drosophila
68. Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments
69. High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene
70. Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos
71. Two Drosophila actin genes in detail: gene structure, protein structure, and transcription during development
72. Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila
73. The structure and function of the homeodomain
74. Transposition of cloned P elements into Drosophila germ line chromosomes
75. Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos
76. Regulation of the Ultrabithorax gene of Drosophila by other bithorax complex genes
77. A non-radioactive in situ hybridization method for the localization of specific RNAs in the Drosophila embryo reveals translational control of the segmentation gene hunchback
78. Drosophila homeotic genes encode transcriptional activators similar to mammalian OTF-2
79. Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
80. Protein products of the bithorax complex in Drosophila
81. Distribution of Ultrabithorax proteins in Drosophila
82. Specificity of embryonic lethal mutations in Drosophila analysed in germ line clones
83. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster III Zygotic loci on the X chromosome and the fourth chromosome
84. Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells
85. The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene