Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Cell

Volumn 71, Issue 4, 1992, Pages 691-700

  Tkachuk, Douglas C ^a   Kohler, Sabine ^a   Cleary, Michael L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LEUKEMIA; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME BAND; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; DNA BINDING; DROSOPHILA; GENE ACTIVATION; GENE MAPPING; GENETIC CODE; GENETIC TRANSCRIPTION; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

ACUTE DISEASE; AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 19; DNA-BINDING PROTEINS; DROSOPHILA; GENE EXPRESSION REGULATION, LEUKEMIC; HUMAN; LEUKEMIA; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSLOCATION (GENETICS); ZINC FINGERS;

ANIMALIA; BACTERIA (MICROORGANISMS); DROSOPHILA TRITHORAX; MAMMALIA;

EID: 0026454451     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(92)90602-9     Document Type: Article

References (46)

1. Isolation and sequencing of cDNA clones encoding Drosophila chromosomal protein D1
2. Prosite: a dictionary of sites and patterns in proteins
3. Interactions of Poly-comb and trithorax with cis regulatory regions of Ultrabithorax during the development of Drosophila melanogaster
4. Breakpoint clustering in t(4;11)(q21;q23) acute leukemias
5. “SPKK” motifs prefer to bind DNA at AT-rich sites
6. Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations
7. An altered 11-kilobase transcript in leukemic cell lines with the t(4;11)(q21;q23) chromosome translocation
8. Oncogenic conversion of transcription factors by chromosomal translocations
9. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
10. CD3G is within 200 kb of the leukemic t(4;11) translocation breakpoint
11. Cloning of cDNAs coding for human HMG-1 and HMG-Y proteins: both are capable of binding to the octamer sequence motif
12. A poly(dA-dT) upstream activating sequence binds high-mobility group I proteins and contributes to lymphotoxin (tumor necrosis factor-β) gene regulation
13. Integration host factor: a protein for all reasons
14. Variant translocations (9;11): identification of the critical genetic rearrangement
15. 11;19 translocation in a congenital leukemia with two cell populations of lymphoblasts and monoblasts
16. Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes
17. Genetic control of the spatial pattern of selector gene expression in Drosophila
18. Zinc finger gene database
19. Clinical characteristics of infant acute leukemia with or without 11q23 translocations
20. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: a framework for understanding homeodomain-DNA interactions
21. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
22. The involvement of NF-κB in β-interferon gene regulation reveals its role as a widely inducible mediator of signal transduction
23. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
24. Positive and negative control of human interferon-β gene expression
25. The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains
26. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1
27. A human α-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers
28. Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
29. Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia
30. Acute myeloid leukemias in children treated with epipodophyllotoxins for acute lymphoblastic leukemia
31. Translocations, master genes, and differences between the origins of acute and chronic leukemias
32. Childhood acute lymphoblastic leukemia with chromosomal breakpoints at 11q23
33. The AT-DNA-binding domain of mamalian high mobility group I chromosomal proteins: a novel peptide motif for recognizing DNA structure
34. Phosphorylation of the DNA-binding domain of nonhistone high-mobility group I protein by cdc2 kinase: reduction of binding affinity
35. Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome
36. A lineage switch in acute monocytic leukemia
37. Long-term growth of malignant thymocytes in vitro
38. Comparison of biosequences
39. A mammalian high mobility group protein recognizes any stretch of six A-T base pairs in duplex DNA
40. Correction of a nucleotide-excision-repair mutation by human chromosome 19 in hamster-human hybrid cells
41. Cis-acting sequences from mouse rDNA promote plasmid DNA amplification and persistence in mouse cells: implication of HMG-I in their function
42. A DNA binding protein that recognizes oligo(dA)-oligo(dT) tracts
43. Purification and characterization of a high-mobility-group-like DNA-binding protein that stimulates rRNA synthesis in vitro
44. Identification of a gene MLL that spans the breakpoint in 11q23 translocations associated with human leukemias