메뉴 건너뛰기




Volumn 5, Issue 4, 1998, Pages 431-439

Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus

Author keywords

APC; CD40 ligand; Gene therapy; Liver; Macrophage depletion; Recombinant adenovirus

Indexed keywords

BLOOD CLOTTING FACTOR 9; GAMMA INTERFERON; GLYCOPROTEIN GP 39; INTERLEUKIN 10;

EID: 0031942297     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300616     Document Type: Article
Times cited : (43)

References (33)
  • 1
    • 0028533960 scopus 로고
    • The use of DNA viruses as vectors for gene therapy
    • Ali M, Lemoine NR, Ring CJ. The use of DNA viruses as vectors for gene therapy. Gene Therapy 1994; 1: 367-384.
    • (1994) Gene Therapy , vol.1 , pp. 367-384
    • Ali, M.1    Lemoine, N.R.2    Ring, C.J.3
  • 2
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
    • Yang Y et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 1994; 91: 4407-4411.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4407-4411
    • Yang, Y.1
  • 3
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy SK, Black HB, Goldwasser E, Leiden JM. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nature Med 1996; 2: 545-550
    • (1996) Nature Med , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3    Leiden, J.M.4
  • 4
    • 0030770344 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors
    • Song W, Kong H-L, Traktman P, Crystal RG. Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors. Hum Gene Ther 1997; 8: 1207-1217.
    • (1997) Hum Gene Ther , vol.8 , pp. 1207-1217
    • Song, W.1    Kong, H.-L.2    Traktman, P.3    Crystal, R.G.4
  • 5
    • 0030824640 scopus 로고    scopus 로고
    • Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: Comparison of E2a wild-type and E2a-deleted vectors
    • Morral N et al. Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild-type and E2a-deleted vectors. Hum Gene Ther 1997; 8: 1275-1286.
    • (1997) Hum Gene Ther , vol.8 , pp. 1275-1286
    • Morral, N.1
  • 6
    • 0028934815 scopus 로고
    • Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
    • Dai Y et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci USA 1995; 92: 1401-1405.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1401-1405
    • Dai, Y.1
  • 7
    • 0028484704 scopus 로고
    • MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
    • Yang Y, Ertl HC, Wilson JM. MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1994; 1: 433-442.
    • (1994) Immunity , vol.1 , pp. 433-442
    • Yang, Y.1    Ertl, H.C.2    Wilson, J.M.3
  • 8
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 9
    • 0027521773 scopus 로고
    • Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
    • Smith TA et al. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat Genet 1993; 5: 397-402.
    • (1993) Nat Genet , vol.5 , pp. 397-402
    • Smith, T.A.1
  • 10
    • 0028914687 scopus 로고
    • Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains
    • Barr D et al. Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Therapy 1995; 2: 151-155.
    • (1995) Gene Therapy , vol.2 , pp. 151-155
    • Barr, D.1
  • 11
    • 0030023343 scopus 로고    scopus 로고
    • Systemic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector
    • Dong J-Y et al. Systemic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector. Hum Gene Ther 1996; 7: 319-331.
    • (1996) Hum Gene Ther , vol.7 , pp. 319-331
    • Dong, J.-Y.1
  • 12
  • 13
    • 0028291947 scopus 로고
    • Surface proteins involved in T cell costimulation
    • Mondino A, Jenkins MK. Surface proteins involved in T cell costimulation. J Leuk Biol 1994; 55: 805-815.
    • (1994) J Leuk Biol , vol.55 , pp. 805-815
    • Mondino, A.1    Jenkins, M.K.2
  • 14
    • 0027499535 scopus 로고
    • Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal
    • Ranheim EA, Kipps TJ. Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal. J Exp Med 1993; 177: 925-935.
    • (1993) J Exp Med , vol.177 , pp. 925-935
    • Ranheim, E.A.1    Kipps, T.J.2
  • 15
    • 0028033310 scopus 로고
    • Activation of human dentritic cells through CD40 cross-linking
    • Caux C et al. Activation of human dentritic cells through CD40 cross-linking. J Exp Med 1994; 180: 1263-1272.
    • (1994) J Exp Med , vol.180 , pp. 1263-1272
    • Caux, C.1
  • 16
    • 0028935411 scopus 로고
    • Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses
    • Roy M et al. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur J Immunol 1995; 25: 596-603.
    • (1995) Eur J Immunol , vol.25 , pp. 596-603
    • Roy, M.1
  • 17
    • 0028863865 scopus 로고
    • B7/CD28-dependent and -independent induction of CD40 ligand expression
    • Ding L, Green JM, Thompson CB, Shevach EM. B7/CD28-dependent and -independent induction of CD40 ligand expression. J Immunol 1995; 155: 5124-5132.
    • (1995) J Immunol , vol.155 , pp. 5124-5132
    • Ding, L.1    Green, J.M.2    Thompson, C.B.3    Shevach, E.M.4
  • 18
    • 0029790327 scopus 로고    scopus 로고
    • Prevention of immune reactions triggered by first-generation adenoviral vectors by monoclonal antibodies and CTLA4Ig
    • Guerette B et al. Prevention of immune reactions triggered by first-generation adenoviral vectors by monoclonal antibodies and CTLA4Ig. Hum Gene Ther 1996; 7: 1455-1463.
    • (1996) Hum Gene Ther , vol.7 , pp. 1455-1463
    • Guerette, B.1
  • 19
    • 0029113869 scopus 로고
    • Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration
    • Kay MA et al. Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat Genet 1995; 11: 191-197.
    • (1995) Nat Genet , vol.11 , pp. 191-197
    • Kay, M.A.1
  • 20
    • 0029817036 scopus 로고    scopus 로고
    • Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
    • Yang Y et al. Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues. J Virol 1996; 70: 6370-6377.
    • (1996) J Virol , vol.70 , pp. 6370-6377
    • Yang, Y.1
  • 21
    • 0030984335 scopus 로고    scopus 로고
    • Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver
    • Kay MA et al. Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver. Proc Natl Acad Sci USA 1997; 94: 4686-4691.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4686-4691
    • Kay, M.A.1
  • 22
    • 0028111256 scopus 로고
    • Liposome-mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
    • van Rooijen N, Sanders A. Liposome-mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Meth 1994; 174: 83-93.
    • (1994) J Immunol Meth , vol.174 , pp. 83-93
    • Van Rooijen, N.1    Sanders, A.2
  • 23
    • 0026902260 scopus 로고
    • Macrophages as accessory cells in the in vivo humoral immune response: From processing of particulate antigens to regulation by suppression
    • van Rooijen N. Macrophages as accessory cells in the in vivo humoral immune response: from processing of particulate antigens to regulation by suppression. Semin Immunol 1992; 4: 237-245.
    • (1992) Semin Immunol , vol.4 , pp. 237-245
    • Van Rooijen, N.1
  • 24
    • 0029093070 scopus 로고
    • Up-regulation of class I major histocompatibility complex antigens by interferon γ is necessary for T cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo
    • Yang Y, Xiang Z, Ertl HC, Wilson JM. Up-regulation of class I major histocompatibility complex antigens by interferon γ is necessary for T cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proc Natl Acad Sci USA 1995; 92: 7257-7261.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7257-7261
    • Yang, Y.1    Xiang, Z.2    Ertl, H.C.3    Wilson, J.M.4
  • 25
    • 0030460164 scopus 로고    scopus 로고
    • Interleukin-12 production by dendritic cells. the role of CD40-CD40L interactions in Th1 T cell responses
    • Kelsall BL, Stuber E, Neurath M, Strober W. Interleukin-12 production by dendritic cells. The role of CD40-CD40L interactions in Th1 T cell responses. Ann NY Acad Sci 1996; 795: 116-126.
    • (1996) Ann NY Acad Sci , vol.795 , pp. 116-126
    • Kelsall, B.L.1    Stuber, E.2    Neurath, M.3    Strober, W.4
  • 26
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon DT, Locksley RM. The instructive role of innate immunity in the acquired immune response. Science 1996; 272: 50-54.
    • (1996) Science , vol.272 , pp. 50-54
    • Fearon, D.T.1    Locksley, R.M.2
  • 27
    • 0031060294 scopus 로고    scopus 로고
    • Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ
    • Wolff G et al. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J Virol 1997; 71: 624-629.
    • (1997) J Virol , vol.71 , pp. 624-629
    • Wolff, G.1
  • 28
    • 0029803090 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of human FIX gene in immunodeficient and normal mice: Evidence for prolonged stability and activity of the transgene in liver
    • Yao S et al. Adenovirus-mediated transfer of human FIX gene in immunodeficient and normal mice: evidence for prolonged stability and activity of the transgene in liver. Viral Immunol 1996; 9: 141-153.
    • (1996) Viral Immunol , vol.9 , pp. 141-153
    • Yao, S.1
  • 29
    • 0027493906 scopus 로고
    • In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39
    • Foy TM et al. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J Exp Med 1993; 178: 1567-1575.
    • (1993) J Exp Med , vol.178 , pp. 1567-1575
    • Foy, T.M.1
  • 30
    • 0026906987 scopus 로고
    • Adenovirus-mediated in vivo gene transfer and expression in normal rat liver
    • Jaffe HA et al. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nat Genet 1992; 1: 372-378.
    • (1992) Nat Genet , vol.1 , pp. 372-378
    • Jaffe, H.A.1
  • 31
    • 0028280433 scopus 로고
    • Expression of Escherichia coli β-galactosidase and rat HPRT in the CNS of Macaca mulatta following adenoviral-mediated gene transfer
    • Davidson BL et al. Expression of Escherichia coli β-galactosidase and rat HPRT in the CNS of Macaca mulatta following adenoviral-mediated gene transfer. Exp Neurol 1994; 125: 258-267.
    • (1994) Exp Neurol , vol.125 , pp. 258-267
    • Davidson, B.L.1
  • 32
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973; 52: 456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van der Eb, A.J.2
  • 33
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle RJ et al. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc Natl Acad Sci USA 1992; 89: 6550-6554.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6550-6554
    • Noelle, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.