Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death

Nature Biotechnology

Volumn 16, Issue 3, 1998, Pages 286-291

  Ferrer Montiel, Antonio V ^a   Merino, Jaime M ^a   Blondelle, Sylvie E ^b   Perez Payà, Enrique ^b,c   Houghten, Richard A ^b   Montal, Mauricio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Combinatorial chemistry; Drug discovery; Glutamate receptor; Ion channel blockers; Neuroprotection

Indexed keywords

GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; EMBRYO; NERVE CELL NECROSIS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; STROKE;

ANIMALS; ARGININE; BINDING, COMPETITIVE; CELL DEATH; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FEMALE; HIPPOCAMPUS; HUMANS; NEURONS; OOCYTES; PEPTIDES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SUBSTRATE SPECIFICITY; XENOPUS;

EID: 0031934090     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0398-286     Document Type: Article

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