Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice

Infection and Immunity

Volumn 65, Issue 2, 1997, Pages 457-465

  Santos Lima, Eduardo César ^a   Garcia, Irene ^b   Vicentelli, Marie Hélene ^a   Vassalli, Pierre ^b   Minoprio, Paola ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; IMMUNOPATHOLOGY; INFECTION; INFLAMMATION; LYMPHOCYTE SUBPOPULATION; MORTALITY; MOUSE; MYOCARDITIS; NONHUMAN; PARASITE CONTROL; PRIORITY JOURNAL; SPLEEN CELL; TRANSGENIC MOUSE; TRYPANOSOMA CRUZI;

EID: 0008953208     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.2.457-465.1997     Document Type: Article

References (51)

1. Abrahamsohn, I. A., and R. L. Coffman. 1995. Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection. J. Immunol. 155:3955-3963.
2. Andrade, Z. A. 1983. Mechanism of myocardial damage in Trypanosoma cruzi infection. Ciba Found. Symp. 99:214-232.
3. Black, C. M., D. M. Israelski, Y. Suzuki, and J. S. Remington. 1989. Effect of recombinant tumour necrosis factor on acute infection in mice with Toxoplasma gondii or Trypanosoma cruzi. Immunology 68:570-574.
4. Culbertson, J. T., and W. R. Kessler. 1942. Age resistance of mice to Trypanosoma cruzi. J. Parasitol. 28:155-158.
5. d'Imperio-Lima, M. R., M. Joskowicz, A. Coutinho, T. Kipnis, and H. Eisen. 1985. Very large and isotypically atypical polyclonal plaque-forming cell responses in mice infected with Trypanosoma cruzi. Eur. J. Immunol. 15:201-203.
6. d'Imperio-Lima, M. R., H. Eisen, P. Minoprio, M. Joskowicz, and A. Coutinho. 1986. Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease. J. Immunol. 137:353-356.
7. Engelmann, H., D. Novick, and D. Wallach. 1990. Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J. Biol. Chem. 265:1531-1536.
8. Flynn, J. L., M. M. Goldstein, J. Chan, K. J. Triebold, K. Pfeffer, C. J. Lowenstein, R. Schreiber, T. W. Mak, and B. Bloom. 1995. Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2:561-572.
9. Garcia, I., Y. Miyazaki, K. Araki, M. Araki, R. Lucas, G. E. Grau, G. Milon, Y. Belkaid, C. Montixi, W. Lesslauer, and P. Vassalli. 1995. Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Eur. J. Immunol. 25:2401-2407.
10. Gazzinelli, R. T., I. P. Oswald, S. Hieny, S. L. James, and A. Sher. 1992. The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β. Eur. J. Immunol. 22:2501-2506.
11. Görgen, I., T. Hartung, M. Leist, M. Niehörster, G. Tiegs, S. Uhlig, F. Weitzel, and A. Wendel. 1992. Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-α. J. Immunol. 149:918-924.
12. Havell, E. 1989. Evidence that tumor necrosis factor has an important role in antibacterial resistance. J. Immunol. 143:2894-2899.
13. Hoft, D. F., R. G. Lynch, and L. V. Kirchhoff. 1993. Kinetic analysis of antigen-specific immune responses in resistant and susceptible mice during infection with Trypanosoma cruzi. J. Immunol. 151:7038-7047.
14. Itohara, S., N. Nakanishi, O. Kanagawa, R. Kubo, and S. Tonegawa. 1989. Monoclonal antibodies specific to native murine T-cell receptor γδ: analysis of γδ T cells during thymic ontogeny and in peripheral lymphoid organs. Proc. Natl. Acad. Sci. USA 86:5094-5098.
15. Kamijo, R., J. Le, D. Shapiro, E. A. Havell, S. Huang, M. Aguet, M. Bosland, and J. Vilcek. 1993. Mice that lack the interferon-γ receptor have profoundly altered responses to infection with bacillus Calmette-Guérin and subsequent challenge with lipopolysaccharide. J. Exp. Med. 178:1435-1440.
16. Kindler, V., A.-P. Sappino, G. E. Grau, P.-F. Piguet, and P. Vassalli. 1989. The inducing role of tumor necrosis factor in the development of bactericidal granuloma during BCG infection. Cell 56:731-740.
17. Kubo, R., W. Born, J. W. Kappler, P. Marrack, and M. Pigeon. 1989. Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J. Immunol. 142:2736-2742.
18. Lesslauer, W., H. Tabuchi, R. Gentz, M. Brockhaus, E. J. Schlaeger, G. Grau, P. F. Piquet, P. Pointaire, P. Vassalli, and H. Loetscher. 1991. Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur. J. Immunol. 21:2883-2886.
19. Lucas, B., K. Smith, and A. Haque. 1995. Plasmodium yoelii in mice: differential induction of cytokine gene expression during hyporesponsiveness induction and restimulation. Cell. Immunol. 160:79-90.
20. Minoprio, P., H. Eisen, M. Joskowicz, P. Pereira, and A. Coutinho. 1987. Suppression of polyclonal antibody production in Trypanosoma cruzi infected mice by treatment with anti-L3T4 antibodies. J. Immunol. 139:545-550.
21. - T cells in the polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. Int. Immunol. 1:176-184.
22. Minoprio, P., S. Itohara, C. Heusser, S. Tonegawa, and A. Coutinho. 1984. Immunobiology of murine T. cruzi infection: the predominance of parasite-nonspecific responses and the activation of TcRI T cells. Immunol. Rev. 112:183-207.
23. Minoprio, P., A. Coutinho, S. Spinella, and M. Hontebeyrie-Joskowicz. 1991. Xid immunodeficiency imparts increased parasite clearance and resistance to pathology in experimental Chagas' disease. Int. Immunol. 3:427-433.
24. Minoprio, P., M. Cury-El-Cheikh, E. Murphy, M. Hontebeyrie-Joskowicz, R. Coffman, A. Coutinho, and A. O'Garra. 1993. Xid-associated resistance to experimental Chagas' disease is IFN-γ-dependent. J. Immunol. 151:4200-4208.
25. Muñoz-Fernandez, M. A., M. A. Fernandez, and M. Fresno. 1992. Synergism between tumor necrosis factor-α and interferon-γ on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur. J. Immunol. 22:301-307.
26. Nogueira, N., and Z. Cohn. 1978. Trypanosoma cruzi: in vitro induction of macrophage microbicidal activity. J. Exp. Med. 148:288-292.
27. Østensen, M. E., D. L. Thiele, and P. E. Lipsky. 1987. Tumor necrosis factor-α enhances cytolytic activity of human natural killer cells. J. Immunol. 138:4185-4191.
28. Petray, P. B., M. E. Rottenberg, G. Bertot, R. S. Corral, A. Diaz, A. Örn, and S. Grinstein. 1993. Effects of anti-γ-interferon and anti-interleukin-4 administration on the resistance of mice against infection with reticulotropic and myotropic strains of Trypanosoma cruzi. Immunol. Lett. 35:77-80.
29. Pfeffer, K., T. Matsuyama, T. M. Kündig, A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P. S. Ohashi, M. Krönke, and T. W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73:457-467.
30. Ramos, C., E. Lamoy, M. Feoli, M. Rodriguez, M. Perez, and L. Ortiz-Ortiz. 1978. Trypanosoma cruzi: immunosuppressed response to different antigens in the infected mouse. Exp. Parasitol. 4:190-199.
31. Reed, S., K. H. Grabstein, D. L. Pihl, and P. J. Morrisey. 1990. Recombinant granulocyte-macrophage colony-stimulating factor restores deficient immune responses in mice with chronic Trypanosoma cruzi infections. J. Immunol. 145:1564-1570.
32. Reed, S., C. E. Brownell, D. M. Russo, J. S. Silva, K. H. Grabstein, and P. J. Morrissey. 1994. 1L-10 mediates susceptibility to Trypanosoma cruzi infection. J. Immunol. 153:3135-3140.
33. Rothe, J., W. Lesslauer, H. Lötscher, Y. Lang, P. Koebel, F. Köntgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumor necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364:798-802.
34. Rowland, E. C., and R. E. Kuhn. 1978. Suppression of cellular responses in mice during Trypanosoma cruzi infections. Infect. Immun. 20:393-397.
35. Russo, M., P. Minoprio, A. Coutinho, H. Eisen, and M. Hontebeyrie-Joskowicz. 1988. Depletion of L3T4 T lymphocytes during Trypanosoma cruzi infection inhibits macrophage and B lymphocyte activation but not tissue inflammatory reaction. Mem. Inst. Oswaldo Cruz Rio J. 83:527-538.
36. Russo, M., N. Starobinas, R. Ribeiro-dos-Santos, P. Minoprio, H. Eisen, and M. Hontebeyrie-Joskowicz. 1989. Susceptible mice present higher macrophage activation than resistant mice during infections with myotropic strains of Trypanosoma cruzi. Parasite Immunol. 11:385-395.
37. Santos Lima, E. C., and P. Minoprio. 1996. Chagas' disease is attenuated in mice lacking γδ T cells. Infect. Immun. 64:215-221.
38. Silva, J. S., G. N. R. Vespa, M. A. G. Cardoso, J. C. S. Aliberti, and F. Q. Cunha. 1995. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages. Infect. Immun. 63:4862-4867.
39. Soboslay, P. T., C. M. Dreweck, W. H. Hoffmann, C. G. K. Lüder, C. Heuschkel, H. Görgen, M. Banla, and H. Schulz-Key. 1992. Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment. Clin. Exp. Immunol. 89:407-413.
40. Starobinas, N., M. Russo, P. Minoprio, and M. Hontebeyrie-Joskowicz. 1991. Is TNFα involved in early susceptibility of Trypanosoma cruzi-infected C3H/He mice? Res. Immunol. 142:117-122.
41. Stefani, M. M. A., H. A. Takehara, and I. Mota. 1983. Isotype of antibodies responsible for immune lysis in Trypanosoma cruzi infected mice. Immunol. Lett. 7:91-97.
42. Stenger, S., W. Solbach, M. Rollighoff, and C. Bogdan. 1991. Cytokine interactions in experimental cutaneous leishmaniasis. II. Endogenous tumor necrosis factor-alpha production by macrophages is induced by the synergistic action of interferon (IFN)-gamma and interleukin (IL)-4 and accounts for the antiparasitic effect mediated by IFN-gamma and IL-4. Eur. J. Immunol. 21:1669-1675.
43. Tarleton, R. 1990. Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi. J. Immunol. 144:717-724.
44. Tarleton, R. L. 1988. Tumor necrosis factor (cachectin) producing during experimental Chagas' disease. Clin. Exp. Immunol. 73:186-190.
45. Tarleton, R. L., B. H. Koller, A. Latour, and M. Postan. 1992. Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection. Nature 356:338-340.
46. Tartaglia, L. A., and D. V. Goeddel. 1992. Two TNF receptors. Immunol. Today 13:151-153.
47. Tripp, C. S., S. F. Wolf, and E. R. Unanue. 1993. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 90:3725-3729.
48. Trischmann, T. M., and B. R. Bloom. 1982. Genetics of murine resistance to Trypanosoma cruzi. Infect. Immun. 35:546-551.
49. Truyens, C., F. Torrico, A. Angelo-Barrios, R. Lucas, H. Heremans, P. De Baetselier, and Y. Carlier. 1995. Cachexia in mice infected with Trypanosoma cruzi. Mem. Inst. Oswaldo Cruz Rio J. 90:172.
50. Unkless, J. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580-596.
51. Wrightsman, R., S. Krassner, and J. Watson. 1982. Genetic control of responses to Trypanosoma cruzi in mice: multiple genes influencing parasitemia and survival. Infect. Immun. 36:637-644.