Regulation of T cell immunity and tolerance in vivo by CD4

International Immunology

Volumn 10, Issue 3, 1998, Pages 247-257

  Shen, Xiaoli ^a   König, Rolf ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELLULAR IMMUNITY; CONTROLLED STUDY; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE; TRANSGENE;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD4; CELL LINE; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNE TOLERANCE; MICE; MICE, INBRED BALB C; OVALBUMIN; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 0031889303     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.3.247     Document Type: Article

References (31)

1. König, R., Fleury, S. and Germain, R. N. 1996. The structural basis of CD4-MHC class II interactions: co-receptor contributions to T cell receptor antigen recognition and oligomerization-dependent signal transduction. Curr. Top. Microbiol. Immunol. 205:19.
2. König, R., Huang, L. Y. and Germain, R. N. 1992. MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature 356:796.
3. + T lymphocytes in vitro and in vivo. J. Immunol. 157:87.
4. Osborne, B. A. 1996. Apoptosis and the maintenance of homoeostasis in the immune system. Curr. Opin. Immunol. 8:245.
5. Rocha, B., Grandien, A. and Freitas, A. A. 1995. Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance. J. Exp. Med. 181:993.
6. Schwartz, R. H. 1990. A cell culture model for T lymphocyte clonal anergy. Science 248:1349.
7. + T cells. J. Exp. Med. 185:405.
8. Kearney, E. R., Pape, K. A., Loh, D. Y. and Jenkins, M. K. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
9. 10 thymocytes in vivo. Science 250:1720.
10. Haskins, K., Kubo, R., White, J., Pigeon, M., Kappler, J. and Marrack, P. 1983. The MHC-restricted antigen receptor on T cells. I. Isolation of a monoclonal antibody. J. Exp. Med. 157:1149.
11. Andrew, S. M. and Titus, J. A. 1995. Purification of immunoglobulin G. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M and Strober, W., eds. Current Protocols in Immunology, p. 2.7.1. John Wiley, New York.
12. Holmes, K., Fowlkes, B. J., Schmid, I. and Giorgi, J. V. 1995. Preparation of cells and reagents for flow cytometry. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W., eds, Current Protocols in Immunology, p. 5.3.1. John Wiley, New York.
13. + T cells is regulated by the antigen-presenting cell. J. Immunol. 150:3832.
14. Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F. and Riccardi, C. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271.
15. Huang, L., Soldevila, G., Leeker, M., Flavell, R. A. and Crispe, I. N. 1994. Liver is the site of T cell destruction during peripheral deletion. Immunity 1:741.
16. + T cells. J. Exp. Med. 185:2133.
17. Forsthuber, T., Yip, H. C. and Lehmann, P. V. 1996. Induction of T(h)1 and T(h)2 immunity in neonatal mice. Science 271:1728.
18. Radvanyi, L., Mills, G. B. and Miller, R. G. 1993, Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death. J. Immunol. 150:5704.
19. + T cells responding to a bacterial superantigen. J. Immunol. 154:4302.
20. Boehme, S. A., Zheng, L. and Lenardo, M. J. 1995. Analysis of the CD4 co-receptor and activation-induced co-stimulatory molecules in antigen-mediated mature T lymphocyte death. J. Immunol. 155:1703.
21. Radvanyi, L. G., Shi, Y. F., Vaziri, H., Sharma, A., Dhala, R., Mills, G. B. and Miller, R. G. 1996. CD28 co-stimulation inhibits TCR-induced apoptosis during a primary T cell response. J. Immunol. 156:1788.
22. Boise, L. H., Minn, A. J., Noel, P. J., June, C. H., Accavitti, M. A., Lindsten, T. and Thompson, C. B. 1995. CD28 co-stimulation can promote T cell survival by enhancing the expression of Bcl-xL. Immunity 3:87.
23. Linsley, P. S., Wallace, P. M., Johnson, J., Gibson, M. G., Greene, J. L., Ledbetter, J. A., Singh, C. and Tepper, M. A. 1992. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science 257:792.
24. Combadiere, B., Freedman, M., Chen, L., Shores, E. W., Love, P. and Lenardo, M. J. 1996. Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis. J. Exp. Med. 183:2109.
25. Sloan-Lancaster, J., Shaw, A. S., Rothbard, J. B. and Allen, P. M. 1994. Partial T cell signaling: altered phospho-ζ and lack of Zap70 recruitment in APL-induced T cell anergy. Cell 79:913.
26. Madrenas, J., Wange, R. L., Wang, J. L., Isakov, N., Samelson, L. E. and Germain, R. N. 1995. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 157:515.
27. Rabinowitz, J. D., Beeson, C., Wulfing, C., Tate, K., Allen, P. M., Davis, M. M. and McConnell, H. M. 1996. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity 5:125.
28. McKeithan, T. W. 1995, Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl Acad. Sci. USA 92:5042.
29. h2) responses correlates with peptide affinity for the major histocompatibility complex in self-reactive T cell receptor transgenic mice, J. Exp. Med. 185:583.
30. h2 subset development in the absence of CD4. Immunity 6:559.
31. Ayroldi, E., Migliorati, G., Cannarile, L., Moraca, R., Delfino, D. V. and Riccardi, C. 1997. CD2 rescues T cells from T-cell receptor CDS apoptosis - a role for the Fas/Fas-L system. Blood 89:3717.