-
1
-
-
0023881622
-
Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3: T cell receptor complexes on helper T lymphocytes
-
Anderson P, Blue ML, Schlossman SF (1988) Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3: T cell receptor complexes on helper T lymphocytes. J Immunol 140: 1732-1737
-
(1988)
J Immunol
, vol.140
, pp. 1732-1737
-
-
Anderson, P.1
Blue, M.L.2
Schlossman, S.F.3
-
2
-
-
0025049135
-
Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis
-
Ashkenazi A, Presta LG, Marsters SA, Camerato TR, Rosenthal KA, Fendly BM, Capon DJ (1990) Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis. Proc Natl Acad Sci USA 87. 7150-7154
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7150-7154
-
-
Ashkenazi, A.1
Presta, L.G.2
Marsters, S.A.3
Camerato, T.R.4
Rosenthal, K.A.5
Fendly, B.M.6
Capon, D.J.7
-
3
-
-
0025233576
-
Genetic and mutational analysis of the T-cell antigen receptor
-
Ashwell JD, Klausner RD (1990) Genetic and mutational analysis of the T-cell antigen receptor Annu Rev Immunol 8 139-167
-
(1990)
Annu Rev Immunol
, vol.8
, pp. 139-167
-
-
Ashwell, J.D.1
Klausner, R.D.2
-
4
-
-
0019991519
-
Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens Evidence from studies of cytotoxic T lymphocytes specific for SB antigens
-
Biddison WE, Rao PE, Talle MA, Goldstein G, Shaw S (1982) Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens Evidence from studies of cytotoxic T lymphocytes specific for SB antigens J Exp Med 156: 1065-1076
-
(1982)
J Exp Med
, vol.156
, pp. 1065-1076
-
-
Biddison, W.E.1
Rao, P.E.2
Talle, M.A.3
Goldstein, G.4
Shaw, S.5
-
5
-
-
0024399827
-
The biologic roles of CD2, CD4, and CD8 in T-Cell activation
-
Bierer BE, Sleckman BP, Ratnofsky SE, Burakoff SJ (1989) The biologic roles of CD2, CD4, and CD8 in T-Cell activation. Annu Rev Immunol 7 579-599
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 579-599
-
-
Bierer, B.E.1
Sleckman, B.P.2
Ratnofsky, S.E.3
Burakoff, S.J.4
-
6
-
-
0023176346
-
Structure of the human class I histocompatibility antigen, HLA-A2
-
Bjorkman PJ, Saper MA, Samraoui B, Bennett WS, Strominger JL, Wiley DC (1987) Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329 506-512
-
(1987)
Nature
, vol.329
, pp. 506-512
-
-
Bjorkman, P.J.1
Saper, M.A.2
Samraoui, B.3
Bennett, W.S.4
Strominger, J.L.5
Wiley, D.C.6
-
7
-
-
0025201353
-
Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules
-
Bowman MR, MacFerrin KD, Schreiber SL, Burakoff SJ (1990) Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules Proc Natl Acad Sci USA, 87 9052-9056
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 9052-9056
-
-
Bowman, M.R.1
MacFerrin, K.D.2
Schreiber, S.L.3
Burakoff, S.J.4
-
8
-
-
0023189892
-
Allele-specific control of la molecule surface expression and conformation: Implications for a general model of la structure-function relationships
-
Braunstein NS, Germain RN (1987) Allele-specific control of la molecule surface expression and conformation: implications for a general model of la structure-function relationships. Proc Natl Acad Sci USA 84: 2921-2925
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2921-2925
-
-
Braunstein, N.S.1
Germain, R.N.2
-
9
-
-
0025278031
-
Analysis of the site in CD4 that binds to the HIV envelope glycoprotein
-
Brodsky MH, Warton M, Myers RM, Littman DR (1990) Analysis of the site in CD4 that binds to the HIV envelope glycoprotein. J Immunol 144: 3078-3086
-
(1990)
J Immunol
, vol.144
, pp. 3078-3086
-
-
Brodsky, M.H.1
Warton, M.2
Myers, R.M.3
Littman, D.R.4
-
10
-
-
0027217789
-
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
-
Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC (1993) Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364: 33-39
-
(1993)
Nature
, vol.364
, pp. 33-39
-
-
Brown, J.H.1
Jardetzky, T.S.2
Gorga, J.C.3
Stern, L.J.4
Urban, R.G.5
Strominger, J.L.6
Wiley, D.C.7
-
11
-
-
0026600191
-
Identification of a CD4 binding site on the β2 domain of HLA-DR molecules
-
Cammarota G, Scheirle A, Takacs B, Doran DM, Knorr R, Bannwarth W, Guardiola J, Sinigaglia F (1992) Identification of a CD4 binding site on the β2 domain of HLA-DR molecules Nature, 356: 799-801
-
(1992)
Nature
, vol.356
, pp. 799-801
-
-
Cammarota, G.1
Scheirle, A.2
Takacs, B.3
Doran, D.M.4
Knorr, R.5
Bannwarth, W.6
Guardiola, J.7
Sinigaglia, F.8
-
12
-
-
0023748691
-
Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding
-
Clayton LK, Hussey RE, Steinbrich R, Ramachandran H, Husain Y, Reinherz EL (1988) Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding. Nature 335 363-366
-
(1988)
Nature
, vol.335
, pp. 363-366
-
-
Clayton, L.K.1
Hussey, R.E.2
Steinbrich, R.3
Ramachandran, H.4
Husain, Y.5
Reinherz, E.L.6
-
13
-
-
0024403580
-
Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding
-
Clayton LK, Sieh M, Pious DA, Reinherz EL (1989) Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding Nature 339: 548-551
-
(1989)
Nature
, vol.339
, pp. 548-551
-
-
Clayton, L.K.1
Sieh, M.2
Pious, D.A.3
Reinherz, E.L.4
-
14
-
-
0028120414
-
T cell receptor/MHC ciass I- peptide interactions: Affinity, kinetics, and specificity
-
Corr M, Slanetz AE, Boyd LF, Jelonek MT, Khilko S, Al-Ramadi BK, Kim YS, Maher SE, Bothwell ALM, Margulies DH (1994) T cell receptor/MHC ciass I- peptide interactions: affinity, kinetics, and specificity. Science 265: 946-949
-
(1994)
Science
, vol.265
, pp. 946-949
-
-
Corr, M.1
Slanetz, A.E.2
Boyd, L.F.3
Jelonek, M.T.4
Khilko, S.5
Al-Ramadi, B.K.6
Kim, Y.S.7
Maher, S.E.8
Bothwell, A.L.M.9
Margulies, D.H.10
-
15
-
-
0025182003
-
The minimal number of class II MHC-antigen complexes needed for T cell activation
-
Demotz S, Grey HM, Sette A (1990) The minimal number of class II MHC-antigen complexes needed for T cell activation Science 249: 1028-1030
-
(1990)
Science
, vol.249
, pp. 1028-1030
-
-
Demotz, S.1
Grey, H.M.2
Sette, A.3
-
16
-
-
0020643474
-
Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: Expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity
-
Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, Fitch FW (1983) Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev 74. 29-56
-
(1983)
Immunol Rev
, vol.74
, pp. 29-56
-
-
Dialynas, D.P.1
Wilde, D.B.2
Marrack, P.3
Pierres, A.4
Wall, K.A.5
Havran, W.6
Otten, G.7
Loken, M.R.8
Pierres, M.9
Kappler, J.10
Fitch, F.W.11
-
17
-
-
0042689324
-
Molecular determinants of immunogenicity: The immunon model of immune response
-
Dintzis HM, Dintzis RZ, Vogelstein B (1976) Molecular determinants of immunogenicity: the immunon model of immune response Proc Natl Acad Sci USA 73: 3671-3675
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 3671-3675
-
-
Dintzis, H.M.1
Dintzis, R.Z.2
Vogelstein, B.3
-
18
-
-
0023521229
-
Interaction between CD4 and class II MHC molecules mediates cell adhesion
-
Doyle C, Strominger JL (1987) Interaction between CD4 and class II MHC molecules mediates cell adhesion Nature 330: 256-259
-
(1987)
Nature
, vol.330
, pp. 256-259
-
-
Doyle, C.1
Strominger, J.L.2
-
19
-
-
0024443411
-
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
-
Dustin ML, Springer TA (1989) T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341: 619-624
-
(1989)
Nature
, vol.341
, pp. 619-624
-
-
Dustin, M.L.1
Springer, T.A.2
-
20
-
-
0019410986
-
Activation of human T lymphocyte subsets: Helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens
-
Engleman EG, Benike CJ, Grumet FC, Evans RL (1981) Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens J Immunol 127: 2124-2129
-
(1981)
J Immunol
, vol.127
, pp. 2124-2129
-
-
Engleman, E.G.1
Benike, C.J.2
Grumet, F.C.3
Evans, R.L.4
-
21
-
-
0022598251
-
T cell clones and T cell receptors
-
Fitch FW (1986) T cell clones and T cell receptors. Microbiol. Rev 50: 50-69
-
(1986)
Microbiol. Rev
, vol.50
, pp. 50-69
-
-
Fitch, F.W.1
-
22
-
-
0025949829
-
Mutational analysis of the interaction between CD4 and class II MHC. class II antigens contact CD4 on a surface opposite the gp120-binding site
-
Fleury S, Lamarre D, Meloche S, Ryu SE, Cantin C, Hendrickson WA, Sekaly RP (1991) Mutational analysis of the interaction between CD4 and class II MHC. class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell 66: 1037-1049
-
(1991)
Cell
, vol.66
, pp. 1037-1049
-
-
Fleury, S.1
Lamarre, D.2
Meloche, S.3
Ryu, S.E.4
Cantin, C.5
Hendrickson, W.A.6
Sekaly, R.P.7
-
23
-
-
0029156737
-
Polymorphism in the β2 domain of HLA-DR affects the interaction with CD4
-
in press
-
Fleury S, Thibodean J, Croteau G, Labrecque N, Aronson H-E, Cantin F, Long EO, Sékaly R-P (1995) Polymorphism in the β2 domain of HLA-DR affects the interaction with CD4. J Exp Med 182 (in press)
-
(1995)
J Exp Med
, vol.182
-
-
Fleury, S.1
Thibodean, J.2
Croteau, G.3
Labrecque, N.4
Aronson, H.-E.5
Cantin, F.6
Long, E.O.7
Sékaly, R.-P.8
-
24
-
-
0023221420
-
Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen
-
Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J, Marrack P (1987) Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature 328: 626-629
-
(1987)
Nature
, vol.328
, pp. 626-629
-
-
Gay, D.1
Maddon, P.2
Sekaly, R.3
Talle, M.A.4
Godfrey, M.5
Long, E.6
Goldstein, G.7
Chess, L.8
Axel, R.9
Kappler, J.10
Marrack, P.11
-
25
-
-
0010112385
-
The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated la
-
Gay D, Buus S, Pasternak J, Marrack P (1988) The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated la. Proc Natl Acad Sci USA 85 5629-5633
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5629-5633
-
-
Gay, D.1
Buus, S.2
Pasternak, J.3
Marrack, P.4
-
26
-
-
0028038426
-
MHC-dependent antigen processing and peptide presentation, providing ligands for T lymphocyte activation
-
Germain RN (1994) MHC-dependent antigen processing and peptide presentation, providing ligands for T lymphocyte activation. Cell 76: 287-299
-
(1994)
Cell
, vol.76
, pp. 287-299
-
-
Germain, R.N.1
-
27
-
-
0021931434
-
T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4
-
Golding H, McCluskey J, Munitz TI, Germain RN, Margulies DH, Singer A (1985) T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4 Nature 317 425-427
-
(1985)
Nature
, vol.317
, pp. 425-427
-
-
Golding, H.1
McCluskey, J.2
Munitz, T.I.3
Germain, R.N.4
Margulies, D.H.5
Singer, A.6
-
29
-
-
0025286210
-
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
-
Harding CV, Unanue ER (1990) Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation Nature 346: 574-576
-
(1990)
Nature
, vol.346
, pp. 574-576
-
-
Harding, C.V.1
Unanue, E.R.2
-
30
-
-
0026681679
-
The T cell receptor as a multicomponent signaling machine: CD4/CD8 coreceptors and CD45 in T cell activation
-
Janeway CA Jr (1992) The T cell receptor as a multicomponent signaling machine: CD4/CD8 coreceptors and CD45 in T cell activation Annu Rev Immunol 10: 645-674
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 645-674
-
-
Janeway Jr., C.A.1
-
31
-
-
0024474324
-
The coreceptor function of murine CD4
-
Janeway CA Jr, Rojo J, Saizawa K, Dianzani U, Portoles P, Tite J, Haque S, Jones B (1989) The coreceptor function of murine CD4. Immunol Rev 109 77-92
-
(1989)
Immunol Rev
, vol.109
, pp. 77-92
-
-
Janeway Jr., C.A.1
Rojo, J.2
Saizawa, K.3
Dianzani, U.4
Portoles, P.5
Tite, J.6
Haque, S.7
Jones, B.8
-
32
-
-
43949169353
-
Distinct roles for CD4 and CD8 as coreceptors in antigen receptor signaling
-
Julius M, Maroun CR, Haughn L (1993) Distinct roles for CD4 and CD8 as coreceptors in antigen receptor signaling. Immunol Today 14: 177-183
-
(1993)
Immunol Today
, vol.14
, pp. 177-183
-
-
Julius, M.1
Maroun, C.R.2
Haughn, L.3
-
33
-
-
0026563077
-
MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8
-
König R, Huang LY, Germain RN (1992) MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature 356 796-798
-
(1992)
Nature
, vol.356
, pp. 796-798
-
-
König, R.1
Huang, L.Y.2
Germain, R.N.3
-
34
-
-
0029150969
-
Involvement of both MHC Class II α and β chains in CD4 function indicates a role for ordered oligomeritation in T Cell activation
-
in press
-
König R, Shen X, Germain RN (1995) Involvement of both MHC Class II α and β chains in CD4 function indicates a role for ordered oligomeritation in T Cell activation. J Exp Med 182 (in press)
-
(1995)
J Exp Med
, vol.182
-
-
König, R.1
Shen, X.2
Germain, R.N.3
-
36
-
-
0025004265
-
Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals
-
Kwong PD, Ryu SE, Hendrickson WA, Axel R, Sweet RM, Folena WG, Hensley P, Sweet RW (1990) Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals Proc Natl Acad Sci USA 87: 6423-6427
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6423-6427
-
-
Kwong, P.D.1
Ryu, S.E.2
Hendrickson, W.A.3
Axel, R.4
Sweet, R.M.5
Folena, W.G.6
Hensley, P.7
Sweet, R.W.8
-
37
-
-
0024386958
-
The MHC-binding and gp120-binding functions of CD4 are separable
-
Lamarre D, Ashkenazi A, Fleury S, Smith DH, Sekaly RP, Capon DJ (1989a) The MHC-binding and gp120-binding functions of CD4 are separable Science 245. 743-746
-
(1989)
Science
, vol.245
, pp. 743-746
-
-
Lamarre, D.1
Ashkenazi, A.2
Fleury, S.3
Smith, D.H.4
Sekaly, R.P.5
Capon, D.J.6
-
38
-
-
0024430146
-
Class II MHC molecules and the HIV gp120 envelope protein interact with functionally distinct regions of the CD4 molecule
-
Lamarre D, Capon DJ, Karp DR, Gregory T, Long EO, Sekaly RP (1989b) Class II MHC molecules and the HIV gp120 envelope protein interact with functionally distinct regions of the CD4 molecule. EMBO J 8: 3271-3277
-
(1989)
EMBO J
, vol.8
, pp. 3271-3277
-
-
Lamarre, D.1
Capon, D.J.2
Karp, D.R.3
Gregory, T.4
Long, E.O.5
Sekaly, R.P.6
-
39
-
-
0023878973
-
The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domian of CD4
-
Landau NR, Warton M, Littman DR (1988) The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domian of CD4 Nature 334. 159-162
-
(1988)
Nature
, vol.334
, pp. 159-162
-
-
Landau, N.R.1
Warton, M.2
Littman, D.R.3
-
41
-
-
0020606071
-
The major histocompatibility complex-restricted antigen receptor on T cells. II Role of the L3T4 Product
-
Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, Fitch F, Kappler J (1993) The major histocompatibility complex-restricted antigen receptor on T cells. II Role of the L3T4 Product. J Exp Med 158 1077-1091
-
(1993)
J Exp Med
, vol.158
, pp. 1077-1091
-
-
Marrack, P.1
Endres, R.2
Shimonkevitz, R.3
Zlotnik, A.4
Dialynas, D.5
Fitch, F.6
Kappler, J.7
-
42
-
-
0026345967
-
Low affinity interaction of peptide-MHC complexes with T cell receptors
-
Matsui K, Boniface JJ, Reay PA, Schild H, Fazekas de St. Groth B, Davis MM (1991) Low affinity interaction of peptide-MHC complexes with T cell receptors. Science 254: 1788-1791
-
(1991)
Science
, vol.254
, pp. 1788-1791
-
-
Matsui, K.1
Boniface, J.J.2
Reay, P.A.3
Schild, H.4
Fazekas De St. Groth, B.5
Davis, M.M.6
-
43
-
-
0025275982
-
Regulation of T helper-B lymphocyte adhesion through CD4-HLA class II interaction
-
Mazerolles F, Amblard F, Lumbroso C, Lecomte O, Van-de-Moortele PF, Barbat C, Piatier-Tonneau D, Auffray C, Fischer A (1990) Regulation of T helper-B lymphocyte adhesion through CD4-HLA class II interaction. Eur J Immunol 20: 637-644
-
(1990)
Eur J Immunol
, vol.20
, pp. 637-644
-
-
Mazerolles, F.1
Amblard, F.2
Lumbroso, C.3
Lecomte, O.4
Van-de-Moortele, P.F.5
Barbat, C.6
Piatier-Tonneau, D.7
Auffray, C.8
Fischer, A.9
-
44
-
-
0021957149
-
Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product
-
McCluskey J, Germain RN, Margulies DH (1985) Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product. Cell 40: 247-257
-
(1985)
Cell
, vol.40
, pp. 247-257
-
-
McCluskey, J.1
Germain, R.N.2
Margulies, D.H.3
-
45
-
-
0023934537
-
Cell surface expression of the amino-terminal domain of Aακ Recognition of an isolated MHC antigenic structure by allospecific T cells but not alloantibodies
-
McCluskey J, Munitz T, Boyd L, Germain RN, Coligan JE, Singer A, Margulies DH (1988) Cell surface expression of the amino-terminal domain of Aακ Recognition of an isolated MHC antigenic structure by allospecific T cells but not alloantibodies. J Immunol 140: 2081-2089
-
(1988)
J Immunol
, vol.140
, pp. 2081-2089
-
-
McCluskey, J.1
Munitz, T.2
Boyd, L.3
Germain, R.N.4
Coligan, J.E.5
Singer, A.6
Margulies, D.H.7
-
46
-
-
0019903680
-
Surface structures involved in target recognition by human cytotoxic T lymphocytes
-
Meuer SC, Hussey RE, Hodgdon JC, Hercend T, Schlossman SF, Reinherz EL (1982) Surface structures involved in target recognition by human cytotoxic T lymphocytes. Science 218: 471-473
-
(1982)
Science
, vol.218
, pp. 471-473
-
-
Meuer, S.C.1
Hussey, R.E.2
Hodgdon, J.C.3
Hercend, T.4
Schlossman, S.F.5
Reinherz, E.L.6
-
47
-
-
0027265402
-
Role of CD4 and CD8 in T cell activation and differentiation
-
Miceli MC, Parnes JR (1993) Role of CD4 and CD8 in T cell activation and differentiation. Adv Immunol 53. 59-122
-
(1993)
Adv Immunol
, vol.53
, pp. 59-122
-
-
Miceli, M.C.1
Parnes, J.R.2
-
48
-
-
0025825530
-
Adhesion versus coreceptor function of CD4 and CD8: Role of the cytoplasmic tail in coreceptor activity
-
Miceli MC, von Hoegen P, Parnes JR (1991) Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity Proc Natl Acad Sci USA 88. 2623-2627
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2623-2627
-
-
Miceli, M.C.1
Von Hoegen, P.2
Parnes, J.R.3
-
49
-
-
0024273639
-
Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis
-
Mizukami T, Fuerst TR, Berger EA, Moss B (1988) Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis. Proc Natl Acad Sci USA 85 9273-9277
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9273-9277
-
-
Mizukami, T.1
Fuerst, T.R.2
Berger, E.A.3
Moss, B.4
-
50
-
-
0027049402
-
Human immunodeficiency virus gp120 binding C′C″ ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules
-
Moebius U, Clayton LK, Abraham S, Diener A, Yunis JJ, Harrison SC, Reinherz EL (1992a) Human immunodeficiency virus gp120 binding C′C″ ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules Proc Natl Acad Sci USA 89: 12008-12012
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 12008-12012
-
-
Moebius, U.1
Clayton, L.K.2
Abraham, S.3
Diener, A.4
Yunis, J.J.5
Harrison, S.C.6
Reinherz, E.L.7
-
51
-
-
0026650992
-
- delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure
-
- delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure. J Exp Med 176 507-517
-
(1992)
J Exp Med
, vol.176
, pp. 507-517
-
-
Moebius, U.1
Clayton, L.K.2
Abraham, S.3
Harrison, S.C.4
Reinherz, E.L.5
-
52
-
-
0027171292
-
Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding
-
Moebius U, Pallai P, Harrison SC, Reinherz EL (1993) Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding Proc Natl Acad Sci USA 90: 8259-8263
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8259-8263
-
-
Moebius, U.1
Pallai, P.2
Harrison, S.C.3
Reinherz, E.L.4
-
53
-
-
0027285589
-
Purified beta-chain of MHC class II binds to CD4 molecules on transfected HeLa cells
-
Nag B, Wada HG, Passmore D, Clark BR, Sharma SD, McConnell HM (1993) Purified beta-chain of MHC class II binds to CD4 molecules on transfected HeLa cells. J Immunol 150: 1358-1364
-
(1993)
J Immunol
, vol.150
, pp. 1358-1364
-
-
Nag, B.1
Wada, H.G.2
Passmore, D.3
Clark, B.R.4
Sharma, S.D.5
McConnell, H.M.6
-
55
-
-
0025253819
-
Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
-
Olshevsky U, Helseth E, Furman C, Li J, Haseltine W, Sodroski J (1990) Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding. J Virol 64: 5701-5707
-
(1990)
J Virol
, vol.64
, pp. 5701-5707
-
-
Olshevsky, U.1
Helseth, E.2
Furman, C.3
Li, J.4
Haseltine, W.5
Sodroski, J.6
-
56
-
-
0021871825
-
HLA class II restriction repertoire of antigen-specific T cells. I The main restriction determinants for antigen presentation are associated with HLA-D/DR and not with DP and DQ
-
Ottenhoff THM, Elferink DG, Hermans J, De Vries RRP (1985) HLA class II restriction repertoire of antigen-specific T cells. I The main restriction determinants for antigen presentation are associated with HLA-D/DR and not with DP and DQ. Hum Immunol 13 105-116
-
(1985)
Hum Immunol
, vol.13
, pp. 105-116
-
-
Ottenhoff, T.H.M.1
Elferink, D.G.2
Hermans, J.3
De Vries, R.R.P.4
-
57
-
-
0024542793
-
Molecular biology and function of CD4 and CD8
-
Parnes JR (1989) Molecular biology and function of CD4 and CD8 Adv Immunol 44: 265-31
-
(1989)
Adv Immunol
, vol.44
, pp. 265-331
-
-
Parnes, J.R.1
-
58
-
-
0024044173
-
Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4
-
Peterson A, Seed B (1988) Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4 Cell 54 65-72
-
(1988)
Cell
, vol.54
, pp. 65-72
-
-
Peterson, A.1
Seed, B.2
-
59
-
-
0024595609
-
Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, Cytotoxic T lymphocytes
-
Potter TA, Rajan TV, Dick RF, Bluestone JA (1989) Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, Cytotoxic T lymphocytes Nature 337 73-75
-
(1989)
Nature
, vol.337
, pp. 73-75
-
-
Potter, T.A.1
Rajan, T.V.2
Dick, R.F.3
Bluestone, J.A.4
-
60
-
-
0026755425
-
Structural analysis of human anti-mouse H-2E xenorecognition T cell receptor bias and impaired CD4 interaction contribute to weak xenoresponses
-
Ramesh P, Barber L, Batchelor JR, Lechler RI (1992) Structural analysis of human anti-mouse H-2E xenorecognition T cell receptor bias and impaired CD4 interaction contribute to weak xenoresponses Int Immunol 4: 935-943
-
(1992)
Int Immunol
, vol.4
, pp. 935-943
-
-
Ramesh, P.1
Barber, L.2
Batchelor, J.R.3
Lechler, R.I.4
-
61
-
-
0026574559
-
T cell receptor aggregation, but not dimerization, induces increased cytosolic calcium concentrations and reveals a lack of stable association between CD4 and the T cell receptor
-
Ratcliffe MJ, Coggeshall KM, Newell MK, Julius MH (1992) T cell receptor aggregation, but not dimerization, induces increased cytosolic calcium concentrations and reveals a lack of stable association between CD4 and the T cell receptor. J Immunol 148. 1643-1651
-
(1992)
J Immunol
, vol.148
, pp. 1643-1651
-
-
Ratcliffe, M.J.1
Coggeshall, K.M.2
Newell, M.K.3
Julius, M.H.4
-
62
-
-
0018866878
-
The differentiation and function of human T lymphocytes
-
Reinherz EL, Schlossman SF (1980) The differentiation and function of human T lymphocytes. Cell 19: 821-827
-
(1980)
Cell
, vol.19
, pp. 821-827
-
-
Reinherz, E.L.1
Schlossman, S.F.2
-
63
-
-
0040226744
-
Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage
-
Reinherz EL, Kung PC, Goldstein G, Levey RH, Schlossman SF (1980) Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage Proc Natl Acad Sci USA, 77 1588-1592
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1588-1592
-
-
Reinherz, E.L.1
Kung, P.C.2
Goldstein, G.3
Levey, R.H.4
Schlossman, S.F.5
-
65
-
-
0010510169
-
Physical association of CD4 and the T cell receptor can be induced by anti-T cell receptor antibodies
-
Rojo JM, Saizawa K, Janeway CA Jr (1989) Physical association of CD4 and the T cell receptor can be induced by anti-T cell receptor antibodies. Proc Natl Acad Sci USA 86: 3311-3315
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3311-3315
-
-
Rojo, J.M.1
Saizawa, K.2
Janeway Jr., C.A.3
-
66
-
-
0025095172
-
HIV-gp120 can block CD4-class II MHC-mediated adhesion
-
Rosenstein Y, Burakoff SJ, Herrmann SH (1990) HIV-gp120 can block CD4-class II MHC-mediated adhesion J Immunol, 144: 526-531
-
(1990)
J Immunol
, vol.144
, pp. 526-531
-
-
Rosenstein, Y.1
Burakoff, S.J.2
Herrmann, S.H.3
-
67
-
-
0024473858
-
The CD4/CD8: P56lck complex in T lymphocytes a potential mechanism to regulate T-cell growth
-
Rudd C, Helms S, Barber EK, Schlossman SF (1989) The CD4/CD8: P56lck complex in T lymphocytes a potential mechanism to regulate T-cell growth. Biochem Cell Biol 67: 581-589
-
(1989)
Biochem Cell Biol
, vol.67
, pp. 581-589
-
-
Rudd, C.1
Helms, S.2
Barber, E.K.3
Schlossman, S.F.4
-
68
-
-
0027398938
-
Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events
-
Ruppert J, Alexander J, Snoke K, Coggeshall M, Herbert E, McKenzie D, Grey HM, Sette A (1993) Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events Proc Natl Acad Sci USA 90, 2671-2675
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2671-2675
-
-
Ruppert, J.1
Alexander, J.2
Snoke, K.3
Coggeshall, M.4
Herbert, E.5
McKenzie, D.6
Grey, H.M.7
Sette, A.8
-
69
-
-
0025224767
-
Crystal structure of an HIV-binding recombinant fragment of human CD4
-
Ryu SE, Kwong PD, Truneh A, Porter TG, Arthos J, Rosenberg M, Dai XP, Xuong NH, Axel R, Sweet RW, Hendrickson WA (1990) Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature, 348: 419-426
-
(1990)
Nature
, vol.348
, pp. 419-426
-
-
Ryu, S.E.1
Kwong, P.D.2
Truneh, A.3
Porter, T.G.4
Arthos, J.5
Rosenberg, M.6
Dai, X.P.7
Xuong, N.H.8
Axel, R.9
Sweet, R.W.10
Hendrickson, W.A.11
-
70
-
-
0023126720
-
Specific antigen-la activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes
-
Saito T, Weiss A, Miller J, Norcross MA, Germain RN (1987) Specific antigen-la activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature 325 125-130
-
(1987)
Nature
, vol.325
, pp. 125-130
-
-
Saito, T.1
Weiss, A.2
Miller, J.3
Norcross, M.A.4
Germain, R.N.5
-
71
-
-
0023280412
-
Evidence for a physical association of CD4 and the CD3 α β T cell receptor
-
Saizawa K, Rojo J, Janeway CA Jr (1987) Evidence for a physical association of CD4 and the CD3 α β T cell receptor. Nature 328. 260-263
-
(1987)
Nature
, vol.328
, pp. 260-263
-
-
Saizawa, K.1
Rojo, J.2
Janeway Jr., C.A.3
-
72
-
-
0025366452
-
A binding site for the T-cell coreceptor CD8 on the α3 domain of HLA-A2
-
Salter RD, Benjamin RJ, Wesley PK, Buxton SE, Garrett TPJ, Clayberger C, Krensky AM, Norment AM, Littman DR, Parham P (1990) A binding site for the T-cell coreceptor CD8 on the α3 domain of HLA-A2. Nature 345: 41-46
-
(1990)
Nature
, vol.345
, pp. 41-46
-
-
Salter, R.D.1
Benjamin, R.J.2
Wesley, P.K.3
Buxton, S.E.4
Garrett, T.P.J.5
Clayberger, C.6
Krensky, A.M.7
Norment, A.M.8
Littman, D.R.9
Parham, P.10
-
73
-
-
0000820364
-
Molecular cloning of the CD2 antigen, the T-celi erythrocyte receptor, by a rapid immunoselection procedure
-
Seed B, Aruffo A (1987) Molecular cloning of the CD2 antigen, the T-celi erythrocyte receptor, by a rapid immunoselection procedure. Proc Natl Acad Sci USA 84. 3365-3369
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3365-3369
-
-
Seed, B.1
Aruffo, A.2
-
75
-
-
0019638514
-
Significance of LyT phenotypes. Lyt-2 antibodies block activities of T cells that recognize class I major histocompatibility complex antigens regardless of their function
-
Swain SL (1981) Significance of LyT phenotypes. Lyt-2 antibodies block activities of T cells that recognize class I major histocompatibility complex antigens regardless of their function Proc Natl Acad Sci U S A , 78 7101-7105
-
(1981)
Proc Natl Acad Sci U S A
, vol.78
, pp. 7101-7105
-
-
Swain, S.L.1
-
76
-
-
0020643477
-
T cell subsets and the recognition of MHC class
-
Swain SL (1983) T cell subsets and the recognition of MHC class Immunol Rev 74: 129-142
-
(1983)
Immunol Rev
, vol.74
, pp. 129-142
-
-
Swain, S.L.1
-
77
-
-
0020674568
-
Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibitity complex-restricted responses
-
Swain SL, Dutton RW, Schwab R, Yamamoto J (1983) Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibitity complex-restricted responses J Exp Med 157 720-729
-
(1983)
J Exp Med
, vol.157
, pp. 720-729
-
-
Swain, S.L.1
Dutton, R.W.2
Schwab, R.3
Yamamoto, J.4
-
78
-
-
0021329218
-
Monoclonal antibody to L3T4 blocks the function of T cells specific for class II major histocompatibility complex antigens
-
Swain SL, Dialynas D, Fitch FW, English MJ (1984) Monoclonal antibody to L3T4 blocks the function of T cells specific for class II major histocompatibility complex antigens J Immunol 132: 1118-1123
-
(1984)
J Immunol
, vol.132
, pp. 1118-1123
-
-
Swain, S.L.1
Dialynas, D.2
Fitch, F.W.3
English, M.J.4
-
79
-
-
0026781186
-
Inhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays
-
Symer DE, Dintzis RZ, Diamond DJ, Dintzis HM (1992) Inhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays J Exp Med 176 1421-1430
-
(1992)
J Exp Med
, vol.176
, pp. 1421-1430
-
-
Symer, D.E.1
Dintzis, R.Z.2
Diamond, D.J.3
Dintzis, H.M.4
-
81
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A, Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity Cell 61 203-212
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
84
-
-
0026535396
-
Species-specific binding of CD4 to the β2 domain of major histocompatibility complex class II molecules
-
Vignali DA, Moreno J, Schiller D, Hämmerling GJ (1992) Species-specific binding of CD4 to the β2 domain of major histocompatibility complex class II molecules. J Exp Med 175 925-932
-
(1992)
J Exp Med
, vol.175
, pp. 925-932
-
-
Vignali, D.A.1
Moreno, J.2
Schiller, D.3
Hämmerling, G.J.4
-
86
-
-
0024146202
-
The developmental biology of T lymphocytes
-
von Boehmer H (1988) The developmental biology of T lymphocytes Annu Rev Immunol 6 309-326
-
(1988)
Annu Rev Immunol
, vol.6
, pp. 309-326
-
-
Von Boehmer, H.1
-
87
-
-
0028032155
-
Positive selection of lymphocytes
-
von Boehmer H (1994) Positive selection of lymphocytes Cell 76: 219-228
-
(1994)
Cell
, vol.76
, pp. 219-228
-
-
Von Boehmer, H.1
-
88
-
-
0024326937
-
Equivalence of human and mouse CD4 in enhancing antigen responses by a mouse class II-restricted T cell hybriodoma
-
von Hoegen P, Miceli MC, Tourvieille B, Schilham M, Parnes JR (1989) Equivalence of human and mouse CD4 in enhancing antigen responses by a mouse class II-restricted T cell hybriodoma. J Exp Med 170. 1879-1886
-
(1989)
J Exp Med
, vol.170
, pp. 1879-1886
-
-
Von Hoegen, P.1
Miceli, M.C.2
Tourvieille, B.3
Schilham, M.4
Parnes, J.R.5
-
89
-
-
0025198478
-
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains
-
Wang JH, Yan YW, Garrett TP, Liu JH, Rodgers DW, Garlick RL, Tarr GE, Husain Y, Reinherz EL, Harrison SC (1990) Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature 348: 411-418
-
(1990)
Nature
, vol.348
, pp. 411-418
-
-
Wang, J.H.1
Yan, Y.W.2
Garrett, T.P.3
Liu, J.H.4
Rodgers, D.W.5
Garlick, R.L.6
Tarr, G.E.7
Husain, Y.8
Reinherz, E.L.9
Harrison, S.C.10
-
90
-
-
0027169408
-
Mouse CD4 binds MHC class II with extremely low affinity
-
Weber S, Karjalainen K (1993) Mouse CD4 binds MHC class II with extremely low affinity Int Immunol 5: 695-698
-
(1993)
Int Immunol
, vol.5
, pp. 695-698
-
-
Weber, S.1
Karjalainen, K.2
-
91
-
-
0026553367
-
Specific low-affinity recogition of major histocompatibility complex plus peptide by soluble T-cell receptor
-
Weber S, Traunecker A, Oliveri F, Gerhard W, Karjalainen K (1992) Specific low-affinity recogition of major histocompatibility complex plus peptide by soluble T-cell receptor Nature 356: 793-796
-
(1992)
Nature
, vol.356
, pp. 793-796
-
-
Weber, S.1
Traunecker, A.2
Oliveri, F.3
Gerhard, W.4
Karjalainen, K.5
-
92
-
-
0021072121
-
Evidence implicating L3T4 in class II MHC antigen-reactivity: Monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines
-
Wilde DB, Marrack P, Kappler J, Dialynas DP, Fitch FW (1983) Evidence implicating L3T4 in class II MHC antigen-reactivity: monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J Immunol 131: 2178-2183
-
(1983)
J Immunol
, vol.131
, pp. 2178-2183
-
-
Wilde, D.B.1
Marrack, P.2
Kappler, J.3
Dialynas, D.P.4
Fitch, F.W.5
-
93
-
-
0027257445
-
A kinase-independent function of Lck in potentiating antigen-specific T cell activation
-
Xu H, Littman DR (1993) A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74 633-643
-
(1993)
Cell
, vol.74
, pp. 633-643
-
-
Xu, H.1
Littman, D.R.2
|