-
1
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, Felgner PL. Direct gene transfer into mouse muscle in vivo. Science. 247:1990;1465-1468.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
Felgner, P.L.7
-
2
-
-
0027411456
-
Heterologous protection against influenza by injection of DNA encoding a viral protein
-
Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Felgner PL, Dwarki VJ, Gromkowski SH, Deck RR, Dewitt CM, Friedman A, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science. 259:1993;1745-1749.
-
(1993)
Science
, vol.259
, pp. 1745-1749
-
-
Ulmer, J.B.1
Donnelly, J.J.2
Parker, S.E.3
Rhodes, G.H.4
Felgner, P.L.5
Dwarki, V.J.6
Gromkowski, S.H.7
Deck, R.R.8
Dewitt, C.M.9
Friedman, A.10
-
3
-
-
0027727903
-
Heterologous and homologous protection against influenza-A by DNA vaccination - Optimization of DNA vectors
-
Montgomery DL, Shiver JW, Leander KR, Perry HC, Friedman A, Martinez D, Ulmer JB, Donnelly JJ, Liu MA. Heterologous and homologous protection against influenza-A by DNA vaccination - optimization of DNA vectors. DNA Cell Biol. 12:1993;777-783.
-
(1993)
DNA Cell Biol
, vol.12
, pp. 777-783
-
-
Montgomery, D.L.1
Shiver, J.W.2
Leander, K.R.3
Perry, H.C.4
Friedman, A.5
Martinez, D.6
Ulmer, J.B.7
Donnelly, J.J.8
Liu, M.A.9
-
4
-
-
0027140509
-
DNA vaccines - Protective immunization by parenteral, mucosal, and gene-gun inoculations
-
Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL. DNA vaccines - protective immunization by parenteral, mucosal, and gene-gun inoculations. Proc Natl Acad Sci USA. 90:1993;11478-11482.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11478-11482
-
-
Fynan, E.F.1
Webster, R.G.2
Fuller, D.H.3
Haynes, J.R.4
Santoro, J.C.5
Robinson, H.L.6
-
6
-
-
0000688754
-
DNA-based immunization overcomes H-2 haplotype-restricted nonresponsiveness to HBsAg in mice
-
F. Brown, R.M. Chanock, M.S. Ginsberg, Lerner R.A. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Davis HL, Michel M-L, Mancini M, Schleef M, Whalen RG. DNA-based immunization overcomes H-2 haplotype-restricted nonresponsiveness to HBsAg in mice. Brown F, Chanock RM, Ginsberg MS, Lerner RA. Vaccines 96. 1996;111-116 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1996)
Vaccines 96
, pp. 111-116
-
-
Davis, H.L.1
Michel, M.-L.2
Mancini, M.3
Schleef, M.4
Whalen, R.G.5
-
7
-
-
0029101242
-
Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice
-
of special interest. Superior immunogenicity against HBsAg was demonstrated by DNA vaccination of mice nonresponsive to HBsAg at the CTL level compared to that demonstrated by recombinant protein or a recombinant vaccinia virus expressing HBsAg.
-
Schirmbeck R, Bohm W, Ando K, Chisari FV, Reimann J. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice. of special interest J Virol. 69:1995;5929-5934 Superior immunogenicity against HBsAg was demonstrated by DNA vaccination of mice nonresponsive to HBsAg at the CTL level compared to that demonstrated by recombinant protein or a recombinant vaccinia virus expressing HBsAg.
-
(1995)
J Virol
, vol.69
, pp. 5929-5934
-
-
Schirmbeck, R.1
Bohm, W.2
Ando, K.3
Chisari, F.V.4
Reimann, J.5
-
8
-
-
0029985146
-
DNA-mediated immunization breaks tolerance in a transgenic mouse model of hepatitis B surface antigen chronic carriers
-
of special interest
-
Mancini M, Hadchouel M, Davis HL, Whalen RG, Toollais P, Michel M-L. DNA-mediated immunization breaks tolerance in a transgenic mouse model of hepatitis B surface antigen chronic carriers. of special interest Proc Natl Acad Sci USA. 1996; The vaccination of HBsAg transgenic mice with HBsAg DNA resulted in the cessation of HBsAg expression and the induction of specific antibodies. The relevance of this model to humans is not known but the data does suggest that the DNA vaccination strategy should be considered for chronic carriers of the virus.
-
(1996)
Proc Natl Acad Sci USA
-
-
Mancini, M.1
Hadchouel, M.2
Davis, H.L.3
Whalen, R.G.4
Toollais, P.5
Michel, M.-L.6
-
9
-
-
0029051152
-
Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus
-
of special interest. This paper demonstrates the efficacy of a combination DNA vaccine, containing several distinct DNA plasmids encoding internal and surface proteins of influenza virus, against a drifted strain of virus and compares efficacy with licensed commercial vaccines.
-
Donnelly JJ, Friedman A, Martinez D, Montgomery DL, Shiver JW, Motzel S, Ulmer JB, Liu MA. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. of special interest Nat Med. 1:1995;583-587 This paper demonstrates the efficacy of a combination DNA vaccine, containing several distinct DNA plasmids encoding internal and surface proteins of influenza virus, against a drifted strain of virus and compares efficacy with licensed commercial vaccines.
-
(1995)
Nat Med
, vol.1
, pp. 583-587
-
-
Donnelly, J.J.1
Friedman, A.2
Martinez, D.3
Montgomery, D.L.4
Shiver, J.W.5
Motzel, S.6
Ulmer, J.B.7
Liu, M.A.8
-
10
-
-
16044372353
-
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine
-
of special interest. This paper, together with [11], provides the first demonstrations of efficacy in animal models for tuberculosis. Importantly, DNA vaccines encoding single M. tuberculosis or M. leprae (see [11]) antigens were found to confer protection equivalent to the widely used bacille Calmette Guerin (BCG) vaccine itself.
-
Huygen K, Content J, Denis O, Montgomery DL, Yawman AM, Deck RR, DeWitt CM, Orme IM, Baldwin S, D'Souza CS, et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. of special interest Nat Med. 2:1996;893-898 This paper, together with [11], provides the first demonstrations of efficacy in animal models for tuberculosis. Importantly, DNA vaccines encoding single M. tuberculosis or M. leprae (see [11]) antigens were found to confer protection equivalent to the widely used bacille Calmette Guerin (BCG) vaccine itself.
-
(1996)
Nat Med
, vol.2
, pp. 893-898
-
-
Huygen, K.1
Content, J.2
Denis, O.3
Montgomery, D.L.4
Yawman, A.M.5
Deck, R.R.6
DeWitt, C.M.7
Orme, I.M.8
Baldwin, S.9
D'Souza, C.S.10
-
11
-
-
0029796404
-
Vaccination against tuberculosis by DNA injection
-
of special interest. See annotation [10].
-
Tascon RE, Colston MJ, Ragno S, Stavropoulos E, Gregory D, Lowrie DB. Vaccination against tuberculosis by DNA injection. of special interest Nat Med. 2:1996;888-892 See annotation [10].
-
(1996)
Nat Med
, vol.2
, pp. 888-892
-
-
Tascon, R.E.1
Colston, M.J.2
Ragno, S.3
Stavropoulos, E.4
Gregory, D.5
Lowrie, D.B.6
-
12
-
-
0029796099
-
Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity
-
h2-type phenotype, an observation unlike others reported for many other DNA vaccines.
-
h2-type phenotype, an observation unlike others reported for many other DNA vaccines.
-
(1996)
Nat Med
, vol.2
, pp. 899-905
-
-
Waisman, A.1
Ruiz, P.J.2
Hirschberg, D.L.3
Gelman, A.4
Oksenberg, J.R.5
Brocke, S.6
Mor, F.7
Cohen, I.8
Steinman, L.9
-
13
-
-
0029664297
-
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
-
of special interest. This paper, together with [14], provides an exciting and potentially effective means of treating allergies.
-
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, Swain SL, Spiegelberg HL, Carson DA. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. of special interest Proc Natl Acad Sci USA. 33:1996;5141-5145 This paper, together with [14], provides an exciting and potentially effective means of treating allergies.
-
(1996)
Proc Natl Acad Sci USA
, vol.33
, pp. 5141-5145
-
-
Raz, E.1
Tighe, H.2
Sato, Y.3
Corr, M.4
Dudler, J.A.5
Roman, M.6
Swain, S.L.7
Spiegelberg, H.L.8
Carson, D.A.9
-
14
-
-
0029925502
-
Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
-
of special interest. See annotation [13].
-
Hsu C-H, Chua K-Y, Tao M-H, Lai Y-L, Wu H-D, Huang S-K, Hsieh K-H. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. of special interest Nat Med. 2:1996;540-544 See annotation [13].
-
(1996)
Nat Med
, vol.2
, pp. 540-544
-
-
Hsu, C.-H.1
Chua, K.-Y.2
Tao, M.-H.3
Lai, Y.-L.4
Wu, H.-D.5
Huang, S.-K.6
Hsieh, K.-H.7
-
15
-
-
0026625208
-
Unique palindromic sequences in synthetic oligonucleotides are required to induce TNF and augment TNF-mediated natural killer activity
-
Yamamoto S, Yamamoto T, Kataoka T, Kuramoto E, Yano O, Tokunaga T. Unique palindromic sequences in synthetic oligonucleotides are required to induce TNF and augment TNF-mediated natural killer activity. J Immunol. 148:1992;4072-4076.
-
(1992)
J Immunol
, vol.148
, pp. 4072-4076
-
-
Yamamoto, S.1
Yamamoto, T.2
Kataoka, T.3
Kuramoto, E.4
Yano, O.5
Tokunaga, T.6
-
16
-
-
0026006734
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
-
Messina JP, Gilkeson GS, Pisetsky DS. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J Immunol. 147:1991;1759-1764.
-
(1991)
J Immunol
, vol.147
, pp. 1759-1764
-
-
Messina, J.P.1
Gilkeson, G.S.2
Pisetsky, D.S.3
-
17
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
of outstanding interest. This paper, together with [15,16], demonstrated the immunostimulatory effects of specific bacterial DNA sequences on lymphocytes.
-
Krieg AM, Yi A-K, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM. CpG motifs in bacterial DNA trigger direct B-cell activation. of outstanding interest Nature. 374:1995;546-549 This paper, together with [15,16], demonstrated the immunostimulatory effects of specific bacterial DNA sequences on lymphocytes.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.-K.2
Waldschmidt, T.J.3
Bishop, G.A.4
Teasdale, R.5
Koretzky, G.A.6
Klinman, D.M.7
-
18
-
-
8944253295
-
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization
-
of special interest. A demonstration in mice of the potential effectiveness of the presence of immunostimulatory CpG motifs in DNA vaccine vectors. Further work will be needed to determine whether the specific sequence or position of the motif was the key to the enhanced immunogenicity and whether other motifs play a role.
-
Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen M-D, Silverman GJ, Lotz M, Carson D, Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. of special interest Science. 273:1996;352-354 A demonstration in mice of the potential effectiveness of the presence of immunostimulatory CpG motifs in DNA vaccine vectors. Further work will be needed to determine whether the specific sequence or position of the motif was the key to the enhanced immunogenicity and whether other motifs play a role.
-
(1996)
Science
, vol.273
, pp. 352-354
-
-
Sato, Y.1
Roman, M.2
Tighe, H.3
Lee, D.4
Corr, M.5
Nguyen, M.-D.6
Silverman, G.J.7
Lotz, M.8
Carson, D.9
Raz, E.10
-
19
-
-
0029989274
-
Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ T cell-, interferon γ-, and nitric oxide-dependent immunity
-
of outstanding interest. The authors have expanded the utility of malaria DNA vaccines by the inclusion of additional genes to confer protection in mouse strains of various MHC haplotypes. In addition, they have demonstrated the effector cells responsible for protection.
-
Doolan DL, Sedegah M, Hedstrom RC, Hobart P, Charoenvit Y, Hoffman SL. Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ T cell-, interferon γ-, and nitric oxide-dependent immunity. of outstanding interest J Exp Med. 183:1996;1739-1746 The authors have expanded the utility of malaria DNA vaccines by the inclusion of additional genes to confer protection in mouse strains of various MHC haplotypes. In addition, they have demonstrated the effector cells responsible for protection.
-
(1996)
J Exp Med
, vol.183
, pp. 1739-1746
-
-
Doolan, D.L.1
Sedegah, M.2
Hedstrom, R.C.3
Hobart, P.4
Charoenvit, Y.5
Hoffman, S.L.6
-
20
-
-
0029737350
-
Introduction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells
-
of special interest. This work, together with [21], provides insights into the cells responsible for the presentation of antigen for the induction of CTL after i.m. injection of DNA, where cells of the bone marrow were shown to be required for this processes.
-
Doe B, Selby M, Barnett S, Baenziger J, Walker CM. Introduction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. of special interest Proc Natl Acad Sci USA. 93:1996;8578-8583 This work, together with [21], provides insights into the cells responsible for the presentation of antigen for the induction of CTL after i.m. injection of DNA, where cells of the bone marrow were shown to be required for this processes.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8578-8583
-
-
Doe, B.1
Selby, M.2
Barnett, S.3
Baenziger, J.4
Walker, C.M.5
-
21
-
-
0011819208
-
Antigen presentation by non-muscle cells for MHC class I-restricted cytotoxic T lymphocytes following viral protein expression by muscle cells
-
of special interest
-
Ulmer JB, Deck RR, DeWitt CM, Donnelly JJ, Liu MA. Antigen presentation by non-muscle cells for MHC class I-restricted cytotoxic T lymphocytes following viral protein expression by muscle cells. of special interest Immunology. 1996; See annotation [20].
-
(1996)
Immunology
-
-
Ulmer, J.B.1
Deck, R.R.2
DeWitt, C.M.3
Donnelly, J.J.4
Liu, M.A.5
-
22
-
-
0029965148
-
Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy
-
Liang X, Hartikka J, Sukhu L, Manthorpe M, Hobart P. Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy. Gene Ther. 3:1996;350-356.
-
(1996)
Gene Ther
, vol.3
, pp. 350-356
-
-
Liang, X.1
Hartikka, J.2
Sukhu, L.3
Manthorpe, M.4
Hobart, P.5
-
23
-
-
0025866787
-
Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells
-
Chapman BS, Thayer RM, Vincent KA, Haigwoood NL. Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells. Nucleic Acids Res. 19:1991;3979-3986.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3979-3986
-
-
Chapman, B.S.1
Thayer, R.M.2
Vincent, K.A.3
Haigwoood, N.L.4
-
24
-
-
0029583673
-
Tetracycline-regulated gene expression following direct gene transfer into skeletal mouse muscle
-
Dhawan J, Rando TA, Elson SL, Bujard H, Blau HM. Tetracycline-regulated gene expression following direct gene transfer into skeletal mouse muscle. Somat Cell Mol Genet. 21:1995;233-240.
-
(1995)
Somat Cell Mol Genet
, vol.21
, pp. 233-240
-
-
Dhawan, J.1
Rando, T.A.2
Elson, S.L.3
Bujard, H.4
Blau, H.M.5
-
25
-
-
0025938020
-
Conditions affecting direct gene transfer into rodent muscle in vivo
-
Wolff JA, Williams P, Acsadi G, Jiao S, Jani G, Chong W. Conditions affecting direct gene transfer into rodent muscle in vivo. Biotechniques. 11:1991;474-485.
-
(1991)
Biotechniques
, vol.11
, pp. 474-485
-
-
Wolff, J.A.1
Williams, P.2
Acsadi, G.3
Jiao, S.4
Jani, G.5
Chong, W.6
-
26
-
-
0029912533
-
Plasmid DNA is protected against ultrasonic cavitation-induced damage when complexed to cationic liposomes
-
Wasan EK, Reimer DL, Bally MB. Plasmid DNA is protected against ultrasonic cavitation-induced damage when complexed to cationic liposomes. J Pharm Sci. 85:1996;427-433.
-
(1996)
J Pharm Sci
, vol.85
, pp. 427-433
-
-
Wasan, E.K.1
Reimer, D.L.2
Bally, M.B.3
-
27
-
-
0029099729
-
Cancer gene therapy using plasmid DNA: Pharmacokinetic study of DNA following injection in mice
-
Lew D, Parker SE, Latimer T, Abai AM, Kuwahara-Rundell A, Doh SG, Yang Z-Y, Laface D, Gromkowski SH, Nabel GJ, et al. Cancer gene therapy using plasmid DNA: pharmacokinetic study of DNA following injection in mice. Hum Gene Ther. 6:1995;553-564.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 553-564
-
-
Lew, D.1
Parker, S.E.2
Latimer, T.3
Abai, A.M.4
Kuwahara-Rundell, A.5
Doh, S.G.6
Yang, Z.-Y.7
Laface, D.8
Gromkowski, S.H.9
Nabel, G.J.10
-
28
-
-
0027283418
-
Direct gene transfer into skeletal muscle in vivo: Factors affecting efficiency of transfer and stability of expression
-
Davis HL, Whalen RG, Demeneix BA. Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression. Hum Gene Ther. 4:1993;151-159.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 151-159
-
-
Davis, H.L.1
Whalen, R.G.2
Demeneix, B.A.3
-
29
-
-
0027423430
-
Improved gene transfer by direct plasmid injection associated with generation in mouse skeletal muscle
-
Wells DJ. Improved gene transfer by direct plasmid injection associated with generation in mouse skeletal muscle. FEBS Lett. 332:1993;179-182.
-
(1993)
FEBS Lett
, vol.332
, pp. 179-182
-
-
Wells, D.J.1
-
30
-
-
0027937512
-
Gene transfer in regenerating muscle
-
Vitadello M, Schiaffino MV, Picard A, Scarpa M, Schiaffino S. Gene transfer in regenerating muscle. Hum Gene Ther. 5:1994;11-18.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 11-18
-
-
Vitadello, M.1
Schiaffino, M.V.2
Picard, A.3
Scarpa, M.4
Schiaffino, S.5
-
31
-
-
0027713229
-
Gene therapy by intramuscular injection of plasmid DNA: Studies on firefly luciferase gene expression in mice
-
Manthorpe M, Cornefert-Jensen F, Hartikka J, Felgner J, Rundell A, Margalith M, Dwarki VJ. Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum Gene Ther. 4:1993;419-431.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 419-431
-
-
Manthorpe, M.1
Cornefert-Jensen, F.2
Hartikka, J.3
Felgner, J.4
Rundell, A.5
Margalith, M.6
Dwarki, V.J.7
-
32
-
-
0027070497
-
Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle
-
Wolff JA, Dowty ME, Jiao S, Repetto G, Berg RK, Ludtke JJ, Williams P, Stautterback DB. Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle. J Cell Sci. 103:1992;1249-1259.
-
(1992)
J Cell Sci
, vol.103
, pp. 1249-1259
-
-
Wolff, J.A.1
Dowty, M.E.2
Jiao, S.3
Repetto, G.4
Berg, R.K.5
Ludtke, J.J.6
Williams, P.7
Stautterback, D.B.8
-
33
-
-
0026459987
-
Aerosol gene delivery in vivo
-
Stribling R, Brunette E, Liggit D, Gaensler K, Debs R. Aerosol gene delivery in vivo. Proc Natl Acad Sci USA. 89:1992;11277-11281.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11277-11281
-
-
Stribling, R.1
Brunette, E.2
Liggit, D.3
Gaensler, K.4
Debs, R.5
-
34
-
-
0029891916
-
Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle
-
Mumper RJ, Duguid JG, Anwer K, Barron MK, Nitta H, Rolland AP. Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle. Pharm Res. 13:1996;701-709.
-
(1996)
Pharm Res
, vol.13
, pp. 701-709
-
-
Mumper, R.J.1
Duguid, J.G.2
Anwer, K.3
Barron, M.K.4
Nitta, H.5
Rolland, A.P.6
-
35
-
-
0023811723
-
Receptor-mediated gene delivery and expression in vivo
-
Wu GY, Wu CH. Receptor-mediated gene delivery and expression in vivo. J Biol Chem. 263:1988;14621-14624.
-
(1988)
J Biol Chem
, vol.263
, pp. 14621-14624
-
-
Wu, G.Y.1
Wu, C.H.2
-
37
-
-
0026579897
-
Genetic immunization is a simple method for eliciting an immune response
-
Tang D-C, Devit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature. 356:1992;152-154.
-
(1992)
Nature
, vol.356
, pp. 152-154
-
-
Tang, D.-C.1
Devit, M.2
Johnston, S.A.3
-
38
-
-
0028863527
-
Protection against mycoplasma infecting using expression-library immunization
-
of outstanding interest. The authors extended the basic DNA vaccination strategy to induce protection even when the genome sequence was not known. This technology will need to be reduced to practice but has the potential to identify the protective antigens of a pathogen.
-
Barry MA, Lai WC, Johnston SA. Protection against mycoplasma infecting using expression-library immunization. of outstanding interest Nature. 377:1995;632-635 The authors extended the basic DNA vaccination strategy to induce protection even when the genome sequence was not known. This technology will need to be reduced to practice but has the potential to identify the protective antigens of a pathogen.
-
(1995)
Nature
, vol.377
, pp. 632-635
-
-
Barry, M.A.1
Lai, W.C.2
Johnston, S.A.3
-
39
-
-
0026655684
-
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin - Polylysine - DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
-
Wagner E, Planck C, Zatloukal K, Cotten M, Birnstiel ML. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin - polylysine - DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA. 89:1992;7934-7938.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7934-7938
-
-
Wagner, E.1
Planck, C.2
Zatloukal, K.3
Cotten, M.4
Birnstiel, M.L.5
-
40
-
-
0027511871
-
Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway
-
Michael SI, Huang C-H, Rømer MU, Wagner E, Hu P-C, Curiel DT. Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway. J Biol Chem. 268:1993;6866-6869.
-
(1993)
J Biol Chem
, vol.268
, pp. 6866-6869
-
-
Michael, S.I.1
Huang, C.-H.2
Rømer, M.U.3
Wagner, E.4
Hu, P.-C.5
Curiel, D.T.6
-
41
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem. 270:1995;18997-19007.
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
42
-
-
0024597585
-
Increased expression of DNA cointroduced with nuclear protein in adult rat liver
-
Kaneda Y, Iwai K, Uchida T. Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science. 243:1989;375-378.
-
(1989)
Science
, vol.243
, pp. 375-378
-
-
Kaneda, Y.1
Iwai, K.2
Uchida, T.3
-
43
-
-
0029053818
-
Cytokine gene expression in epidermis with biological effects following injection of naked DNA
-
Hengge U, Chan EF, Foster RA, Walker PS, Vogel JC. Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nat Genet. 10:1995;161-166.
-
(1995)
Nat Genet
, vol.10
, pp. 161-166
-
-
Hengge, U.1
Chan, E.F.2
Foster, R.A.3
Walker, P.S.4
Vogel, J.C.5
-
44
-
-
0028902839
-
Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines
-
Ziang Z, Ertl HC. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity. 2:1995;129-135.
-
(1995)
Immunity
, vol.2
, pp. 129-135
-
-
Ziang, Z.1
Ertl, H.C.2
-
45
-
-
0029915126
-
Selected strategies to augment polynucleotide immunization
-
Conry RM, Widera G, LoBuglio AF, Fuller JT, Moore SE, Barlow DL, Turner J, Yang N-S, Curiel DT. Selected strategies to augment polynucleotide immunization. Gene Ther. 3:1996;67-74.
-
(1996)
Gene Ther
, vol.3
, pp. 67-74
-
-
Conry, R.M.1
Widera, G.2
LoBuglio, A.F.3
Fuller, J.T.4
Moore, S.E.5
Barlow, D.L.6
Turner, J.7
Yang, N.-S.8
Curiel, D.T.9
-
46
-
-
0030022796
-
Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases
-
Irvine KR, Rao JB, Rosenberg S, Restifo NP. Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases. J Immunol. 156:1996;238-245.
-
(1996)
J Immunol
, vol.156
, pp. 238-245
-
-
Irvine, K.R.1
Rao, J.B.2
Rosenberg, S.3
Restifo, N.P.4
-
47
-
-
0002894408
-
Polynucleotide vaccination induces a significant protective immune response against Myobacteria
-
F. Brown, R.M. Chanock, M.S. Ginsberg, Lerner R.A. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Tascon R, Stavropoulos E, Colston MJ, Lowrie DB. Polynucleotide vaccination induces a significant protective immune response against Myobacteria. Brown F, Chanock RM, Ginsberg MS, Lerner RA. Vaccines 96. 1996;45-49 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1996)
Vaccines 96
, pp. 45-49
-
-
Tascon, R.1
Stavropoulos, E.2
Colston, M.J.3
Lowrie, D.B.4
-
48
-
-
0029670726
-
IFN-γ promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides
-
Yi A-K, Chace J, Cowdery JS, Krieg AM. IFN-γ promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides. J Immunol. 156:1996;558-564.
-
(1996)
J Immunol
, vol.156
, pp. 558-564
-
-
Yi, A.-K.1
Chace, J.2
Cowdery, J.S.3
Krieg, A.M.4
-
49
-
-
0029984358
-
CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12 and interferon-γ
-
DM Klinman, Yi A-K, Beaucage SL, Conover J, Krieg AM. CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12 and interferon-γ Proc Nat Acad Sci USA. 93:1996;2879-2883.
-
(1996)
Proc Nat Acad Sci USA
, vol.93
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.-K.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
50
-
-
0028957214
-
Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA
-
Gilkeson GS, Pippen AM, Pisetsky DS. Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. J Clin Invest. 95:1995;1398-1402.
-
(1995)
J Clin Invest
, vol.95
, pp. 1398-1402
-
-
Gilkeson, G.S.1
Pippen, A.M.2
Pisetsky, D.S.3
-
51
-
-
0029923424
-
Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA
-
of special interest. The demonstration of an unexpected attenuating effect of immunization with bacterial DNA on disease and death in a lupus-prone mouse strain.
-
Gilkeson GS, Ruiz P, Pippen AMM, Alexander AL, Lefkowith JB, Pisetsky DS. Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA. of special interest J Exp Med. 183:1996;1389-1397 The demonstration of an unexpected attenuating effect of immunization with bacterial DNA on disease and death in a lupus-prone mouse strain.
-
(1996)
J Exp Med
, vol.183
, pp. 1389-1397
-
-
Gilkeson, G.S.1
Ruiz, P.2
Pippen, A.M.M.3
Alexander, A.L.4
Lefkowith, J.B.5
Pisetsky, D.S.6
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