Death-associated proteins: From gene identification to the analysis of their apoptotic and tumour suppressive functions

Molecular Medicine Today

Volumn 4, Issue 6, 1998, Pages 268-274

  Kissil Phd, Joseph L ^a   Kimchi Phd, Adi ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; AUTOIMMUNE DISEASE; CANCER; CARDIOVASCULAR DISEASE; GENE ISOLATION; HUMAN; REVIEW; TUMOR SUPPRESSOR GENE;

EID: 0031859112     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(98)01263-5     Document Type: Review

References (34)

1. Hengartner M.O., Horvitz R.H. Programmed cell death in C. elegans. Curr. Opin. Genet. Dev. 4:1994;581-586.
2. McCall K.M., Steller H. Facing death in the fly: genetic analysis of apoptosis in Drosophila. Trends Genet. 13:1997;222-226.
3. Wallach D.et al. Cell death induction by receptors of the TNF family: towards a molecular understanding. FEBS Lett. 410:1997;96-106.
4. Tewari M., Dixit V.M. Recent advances in tumor necrosis factor and CD40 signaling. Curr. Opin. Genet. Dev. 6:1997;39-44.
5. Yuan J. Transducing signals of life and death. Curr. Opin. Cell Biol. 9:1997;247-251.
6. Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
7. Deiss L.P., Kimchi A. A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal. Science. 252:1991;117-120.
8. Gabig T.G.et al. Requiem: a novel zinc finger gene essential for apoptosis in myeloid cells. J. Biol. Chem. 269:1994;29515-29519.
9. Gudkov A.V., Roninson I.B. Isolation of genetic supressor elements (GSEs) from random fragment cDNA libraries in retroviral vectors. Methods Mol. Biol. 69:1997;221-240.
10. 2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science. 271:1996;521-525.
11. Grander D.et al. How does interferon exert its cell growth inhibitory effect? Eur. J. Haematol. 59:1997;129-135.
12. Deiss L.P.et al. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9:1995;15-30.
13. Kissil J.L., Kimchi A. Assignment of Death Associated Protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization. Cytogenet. Cell Genet. 77:1997;252.
14. Kissil J.L.et al. Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. J. Biol. Chem. 270:1995;27932-27936.
15. Wang L.et al. Ich-1, an Ice/ced-3 related gene, encodes both positive and negative regulators of programmed cell death. Cell. 78:1994;739-750.
16. Boldin M.P.et al. Involvment of MACH, a novel Mort1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85:1996;803-815.
17. Muzio M.et al. Flice, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death inducing signalling complex. Cell. 85:1996;817-827.
18. 2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity. EMBO J. 16:1997;998-1008.
19. Feinstein E.et al. The death domain: a module shared by proteins with diverse cellular functions. Trends Biochem. Sci. 20:1995;342-344.
20. Levy-Strumpf N.et al. DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. Mol. Cell. Biol. 17:1997;1615-1625.
21. Imataka H.et al. A new translational regulator with homology to eukaryotic translation initiation factor 4G. EMBO J. 16:1997;817-825.
22. Yamanaka S.et al. A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme. Genes Dev. 11:1997;321-333.
23. Haffner R., Oren M. Biochemical properties and biological effects of p53. Curr. Opin. Genet. Dev. 5:1995;84-90.
24. Feinstein E.et al. Assignment of DAP1 and DAPK - genes that positively mediate programmed cell death triggered by IFN-gamma - to chromosome regions 5p12.2 and 9q34.1, respectively. Genomics. 29:1995;305-307.
25. de Klein A.et al. A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia. Nature. 300:1982;765-767.
26. Ellisen L.W.et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell. 66:1991;649-661.
27. Knowles M.A.et al. Allelotype of human bladder cancer. Cancer Res. 54:1994;531-538.
28. Kissil J.et al. DAP kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene. 14:1997;403-407.
29. Laird P.W. Oncogenic mechanisms mediated by DNA methylation. Mol. Med. Today. 3:1997;223-229.
30. Inbal B.et al. DAP kinase links the control of apoptosis to metastasis. Nature. 390:1997;180-184.
31. Deiss L.P.et al. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J. 15:1996;3861-3870.
32. Nicholson D.W., Thornberry N.A. Caspases: killer proteases. Trends Biochem. Sci. 22:1997;299-306.
33. Wu, G.S. et al. Potential role for cathepsin D in p53-dependent tumor supression and chemosensitivity, Oncogene (in press).
34. Shaughnessy J.D.et al. cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G. Genomics. 39:1997;192-197.