-
1
-
-
0023778652
-
Extensive variation of human immunodeficiency virus type-1 in vivo
-
Saag MS, Hahn BH, Gibbons J, Li Y, Parks ES, Parks WP, Shaw GM (1988) Extensive variation of human immunodeficiency virus type-1 in vivo. Nature 334:440-444
-
(1988)
Nature
, vol.334
, pp. 440-444
-
-
Saag, M.S.1
Hahn, B.H.2
Gibbons, J.3
Li, Y.4
Parks, E.S.5
Parks, W.P.6
Shaw, G.M.7
-
2
-
-
0024469503
-
Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations
-
Meyerhans A, Cheynier R, Albert J, Seth M, Kwok S, Sninsky J, Morfeldt-Manson L, Asjo B, Wain-Hobson S (1989) Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations. Cell 58:901-910
-
(1989)
Cell
, vol.58
, pp. 901-910
-
-
Meyerhans, A.1
Cheynier, R.2
Albert, J.3
Seth, M.4
Kwok, S.5
Sninsky, J.6
Morfeldt-Manson, L.7
Asjo, B.8
Wain-Hobson, S.9
-
3
-
-
0022541470
-
Genetic variation in HTLV III/LAV over time in patients with AIDS or at risk for AIDS
-
Hahn BH, Shaw GM, Taylor ME, Redfield RR, Markham PD, Salahuddin SZ, Wong-Staal F, Gallo RC, Parks ES, Parks WP (1986) Genetic variation in HTLV III/LAV over time in patients with AIDS or at risk for AIDS. Science 232:1548-1553
-
(1986)
Science
, vol.232
, pp. 1548-1553
-
-
Hahn, B.H.1
Shaw, G.M.2
Taylor, M.E.3
Redfield, R.R.4
Markham, P.D.5
Salahuddin, S.Z.6
Wong-Staal, F.7
Gallo, R.C.8
Parks, E.S.9
Parks, W.P.10
-
4
-
-
0026552401
-
Rapid generation of sequence variatioon during primary HIV-1 infection
-
Pang S, Shlesinger Y, Daar ES, Moudgil T, Ho DD, Chen I SY (1992) Rapid generation of sequence variatioon during primary HIV-1 infection. AIDS 6:453-460
-
(1992)
AIDS
, vol.6
, pp. 453-460
-
-
Pang, S.1
Shlesinger, Y.2
Daar, E.S.3
Moudgil, T.4
Ho, D.D.5
Chen, I.S.Y.6
-
5
-
-
0030000114
-
Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase
-
Drosopoulos WC, Prasad VR (1996) Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J Virol 70:4834-4838
-
(1996)
J Virol
, vol.70
, pp. 4834-4838
-
-
Drosopoulos, W.C.1
Prasad, V.R.2
-
6
-
-
0030060362
-
Role of methionine 184 in human immunodeficiency virus type 1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis
-
Pandey VN, Kaushik N, Rege N, Sarafianos SG, Yadav PNS, Modak MJ (1996) Role of methionine 184 in human immunodeficiency virus type 1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. Biochemistry 35:2168-2179
-
(1996)
Biochemistry
, vol.35
, pp. 2168-2179
-
-
Pandey, V.N.1
Kaushik, N.2
Rege, N.3
Sarafianos, S.G.4
Yadav, P.N.S.5
Modak, M.J.6
-
7
-
-
13344294407
-
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
-
Wainberg MA, Drosopoulos WC, Salomon H, Hsu M, Borkow G, Parniak MA, Gu Z, Song Q, Manne J, Islam S, Castriota G, Prasad VR (1996) Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science 271:1282-1285
-
(1996)
Science
, vol.271
, pp. 1282-1285
-
-
Wainberg, M.A.1
Drosopoulos, W.C.2
Salomon, H.3
Hsu, M.4
Borkow, G.5
Parniak, M.A.6
Gu, Z.7
Song, Q.8
Manne, J.9
Islam, S.10
Castriota, G.11
Prasad, V.R.12
-
8
-
-
0030755891
-
The fidelity of 3' misinsertion and mispair insertion during DNA synthesis exhibited by two drug-resistant mutants of the reverse transcriptase of human immunodeficiency virus type I with Leu74Val and Glu89Gly
-
Rubinek T, Bakhanashvili M, Taube R, Avidan O, Hizi A (1997) The fidelity of 3' misinsertion and mispair insertion during DNA synthesis exhibited by two drug-resistant mutants of the reverse transcriptase of human immunodeficiency virus type I with Leu74Val and Glu89Gly. Eur J Biochem 247:238-247
-
(1997)
Eur J Biochem
, vol.247
, pp. 238-247
-
-
Rubinek, T.1
Bakhanashvili, M.2
Taube, R.3
Avidan, O.4
Hizi, A.5
-
9
-
-
0029738149
-
Approaches to control drug resistance in HIV: The role of increased polymerase fidelity
-
Prasad VR, Drosopoulos WC, Hamburgh ME (1996) Approaches to control drug resistance in HIV: the role of increased polymerase fidelity. AIDS Res Hum Retroviruses 12:959-963
-
(1996)
AIDS Res Hum Retroviruses
, vol.12
, pp. 959-963
-
-
Prasad, V.R.1
Drosopoulos, W.C.2
Hamburgh, M.E.3
-
10
-
-
0030475226
-
Fidelity of RNA polymerase II transcription controlled by elongation factor TFIIS
-
Jeon CJ, Agarwal K (1996) Fidelity of RNA polymerase II transcription controlled by elongation factor TFIIS. Proc Natl Acad Sci USA 93:13677-13682
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13677-13682
-
-
Jeon, C.J.1
Agarwal, K.2
-
11
-
-
0027761137
-
Multiple RNA polymerase conformations and GreA: Control of the fidelity of transcription
-
Erie DA, Hajiseyedjavadi O, Young MC, von Hippel PH (1993) Multiple RNA polymerase conformations and GreA: control of the fidelity of transcription. Science 262:867-873
-
(1993)
Science
, vol.262
, pp. 867-873
-
-
Erie, D.A.1
Hajiseyedjavadi, O.2
Young, M.C.3
Von Hippel, P.H.4
-
12
-
-
0000436584
-
Retroviral mutation and reverse transcriptase fidelity
-
Preston BD, Garvey N (1992) Retroviral mutation and reverse transcriptase fidelity. Pharm Techol 16:34-52
-
(1992)
Pharm Techol
, vol.16
, pp. 34-52
-
-
Preston, B.D.1
Garvey, N.2
-
14
-
-
0024267430
-
Fidelity of HIV-1 reverse transcriptase
-
Preston BD, Poiesz BJ, Loch LA (1988) Fidelity of HIV-1 reverse transcriptase. Science 242:1168-1171
-
(1988)
Science
, vol.242
, pp. 1168-1171
-
-
Preston, B.D.1
Poiesz, B.J.2
Loch, L.A.3
-
15
-
-
0024853870
-
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase
-
Perrino FW, Preston BD, Sandell LE, Loeb LA (1989) Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. Proc Natl Acad Sci USA 86:8343-8347
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 8343-8347
-
-
Perrino, F.W.1
Preston, B.D.2
Sandell, L.E.3
Loeb, L.A.4
-
16
-
-
0024273119
-
The accuracy of reverse transcriptase from HIV-1
-
Roberts JD, Bebenek K, Kunkel TA (1988) The accuracy of reverse transcriptase from HIV-1. Science 242:1171-1173
-
(1988)
Science
, vol.242
, pp. 1171-1173
-
-
Roberts, J.D.1
Bebenek, K.2
Kunkel, T.A.3
-
17
-
-
0025215849
-
Reverse transcriptases and genomic variability: The accuracy of DNA replication is enzyme specific and sequence dependent
-
Ricchetti M, Buc H (1990) Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. EMBO J 9:1583-1593
-
(1990)
EMBO J
, vol.9
, pp. 1583-1593
-
-
Ricchetti, M.1
Buc, H.2
-
18
-
-
0027215750
-
Error-prone polymerization by HIV-1 reverse transcriptase
-
Bebenek K, Abbotts J, Wilson SH, Kunkel TA (1993) Error-prone polymerization by HIV-1 reverse transcriptase. J Biol Chem 268:10324-10334
-
(1993)
J Biol Chem
, vol.268
, pp. 10324-10334
-
-
Bebenek, K.1
Abbotts, J.2
Wilson, S.H.3
Kunkel, T.A.4
-
19
-
-
0026760911
-
Comparison of HIV-1 and Avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates
-
Yu H, Goodman MF (1992) Comparison of HIV-1 and Avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J Biol Chem 267:10888-10896
-
(1992)
J Biol Chem
, vol.267
, pp. 10888-10896
-
-
Yu, H.1
Goodman, M.F.2
-
20
-
-
0026778009
-
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates
-
Boyer JC, Bebenek K, Kunkel TA (1992) Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. Proc Natl Acad Sci USA 89:6919-6923
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6919-6923
-
-
Boyer, J.C.1
Bebenek, K.2
Kunkel, T.A.3
-
21
-
-
0029075130
-
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
-
Mansky LM, Temin M (1995) Lower In vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol 69:5087-5094
-
(1995)
J Virol
, vol.69
, pp. 5087-5094
-
-
Mansky, L.M.1
Temin, M.2
-
22
-
-
0027976787
-
Restriction and enhancement of human immunodeficiency virus type I replication by modulation of intracellular deoxynucleoside triphosphate pools
-
Meyerhans A, Vartanian JP, Hultgren C, Plikat U, Karlsson A, Wang L, Eriksson S, Wain-Hobson S (1994) Restriction and enhancement of human immunodeficiency virus type I replication by modulation of intracellular deoxynucleoside triphosphate pools. J Virol 68:535-540
-
(1994)
J Virol
, vol.68
, pp. 535-540
-
-
Meyerhans, A.1
Vartanian, J.P.2
Hultgren, C.3
Plikat, U.4
Karlsson, A.5
Wang, L.6
Eriksson, S.7
Wain-Hobson, S.8
-
23
-
-
0029757751
-
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect in the reverse transcriptase enzyme
-
Back NKT, Nijhuis M, Keulen W, Boucher CAB, Oude Essink BB, van Kuilenburg ABP, van Gennip AH, Berkhout B (1996) Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect in the reverse transcriptase enzyme. EMBO J 15:4040-4049
-
(1996)
EMBO J
, vol.15
, pp. 4040-4049
-
-
Back, N.K.T.1
Nijhuis, M.2
Keulen, W.3
Boucher, C.A.B.4
Oude Essink, B.B.5
Van Kuilenburg, A.B.P.6
Van Gennip, A.H.7
Berkhout, B.8
-
24
-
-
0027377963
-
Low levels of deoxynucleotides in peripheral blood lymphocytes: A strategy to inhibit human immunodeficiency virus type 1 replication
-
Gao WY, Cara A, Gallo RC, Lori F (1993) Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication. Proc Natl Acad Sci USA 90:8925-8928
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8925-8928
-
-
Gao, W.Y.1
Cara, A.2
Gallo, R.C.3
Lori, F.4
-
25
-
-
0027948936
-
Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication
-
Lori F, Malykh A, Cara A, Sun D, Weinstein JN, Lisziewicz J, Gallo RC (1994) Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication. Science 266:801-805
-
(1994)
Science
, vol.266
, pp. 801-805
-
-
Lori, F.1
Malykh, A.2
Cara, A.3
Sun, D.4
Weinstein, J.N.5
Lisziewicz, J.6
Gallo, R.C.7
-
26
-
-
0028880566
-
Hydroxyurea and AIDS: An old drug finds a new application?
-
Lori F, Gallo RC (1995) Hydroxyurea and AIDS: an old drug finds a new application? AIDS Res Hum Retroviruses 11: 1149-1151
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 1149-1151
-
-
Lori, F.1
Gallo, R.C.2
-
27
-
-
0030739032
-
HIV genetic variation is directed and restricted by DNA precursor availability
-
Vartanian JP, Plikart U, Henry M, Mahieux R, Guillemot L, Meyerhans A, Wain-Hobson S (1997) HIV genetic variation is directed and restricted by DNA precursor availability. J Mol Biol 270:139-151
-
(1997)
J Mol Biol
, vol.270
, pp. 139-151
-
-
Vartanian, J.P.1
Plikart, U.2
Henry, M.3
Mahieux, R.4
Guillemot, L.5
Meyerhans, A.6
Wain-Hobson, S.7
-
28
-
-
0025977774
-
Selection, recombination, and G to A hypermutation of human immunodeficiency virus type 1 genome
-
Vartanian JP, Meyerhans A, Asjo B, Wain-Hobson S (1991) Selection, recombination, and G to A hypermutation of human immunodeficiency virus type 1 genome. J Virol 65:1779-1788
-
(1991)
J Virol
, vol.65
, pp. 1779-1788
-
-
Vartanian, J.P.1
Meyerhans, A.2
Asjo, B.3
Wain-Hobson, S.4
-
29
-
-
0025030676
-
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: Substitutions, frameshifts, and hypermutations
-
Pathak VK, Temin H (1990) Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations. Proc Natl Acad Sci USA 87:6019-6023
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6019-6023
-
-
Pathak, V.K.1
Temin, H.2
-
30
-
-
0027764391
-
A new type of G→A hypermutation affecting human immunodeficincy virus
-
Fitzgibbon JE, Mazar S, Dubin DT (1993) A new type of G→A hypermutation affecting human immunodeficincy virus. AIDS Res Hum Retroviruses 9:833-838
-
(1993)
AIDS Res Hum Retroviruses
, vol.9
, pp. 833-838
-
-
Fitzgibbon, J.E.1
Mazar, S.2
Dubin, D.T.3
-
31
-
-
0026533755
-
Distinct subsets of retroviruses encode dUTPase
-
Elder JH, Lerner DL, Hasselkus-Light CS, Fontenot DJ, Hunter E, Luciw PA, Montelaro RC, Phillips TR (1992) Distinct subsets of retroviruses encode dUTPase. J Virol 66:1791-1794
-
(1992)
J Virol
, vol.66
, pp. 1791-1794
-
-
Elder, J.H.1
Lerner, D.L.2
Hasselkus-Light, C.S.3
Fontenot, D.J.4
Hunter, E.5
Luciw, P.A.6
Montelaro, R.C.7
Phillips, T.R.8
-
32
-
-
0029153930
-
Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase
-
Lerner DL, Wagaman PC, Phillips TR, Prospero-Garcia O, Henriksen SJ, Fox HS, Bloom FE, Elder JH (1995) Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase. Proc Natl Acad Sci USA 92:7480-7484
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7480-7484
-
-
Lerner, D.L.1
Wagaman, P.C.2
Phillips, T.R.3
Prospero-Garcia, O.4
Henriksen, S.J.5
Fox, H.S.6
Bloom, F.E.7
Elder, J.H.8
-
33
-
-
9044231763
-
Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA alycosylase DNA repair enzyme
-
Bouhamdan M, Benichou S, Rev F, Navurro JM, Agostini I, Spire B, Camonis J, Slupphaug G, Vigne R, Benarous R, Sire J (1996) Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA alycosylase DNA repair enzyme. J Virol 70:697-704
-
(1996)
J Virol
, vol.70
, pp. 697-704
-
-
Bouhamdan, M.1
Benichou, S.2
Rev, F.3
Navurro, J.M.4
Agostini, I.5
Spire, B.6
Camonis, J.7
Slupphaug, G.8
Vigne, R.9
Benarous, R.10
Sire, J.11
-
34
-
-
0030586737
-
The mutation rate of human immunodeficiency virus type 1 is influenced by the vpr gene
-
Mansky LM (1996) The mutation rate of human immunodeficiency virus type 1 is influenced by the vpr gene. Virology 222:391-400
-
(1996)
Virology
, vol.222
, pp. 391-400
-
-
Mansky, L.M.1
-
35
-
-
0027180278
-
Retrovirus variation and reverse transcription: Abnormal transfers result in retrovirus genetic variation
-
Temin HM (1993) Retrovirus variation and reverse transcription: abnormal transfers result in retrovirus genetic variation. Proc Natl Acad Sci USA 90:6900-6903
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6900-6903
-
-
Temin, H.M.1
-
36
-
-
0026486193
-
Mechanism of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase
-
Peliska JA, Benkovic SJ (1992) Mechanism of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase. Science 258;1112-1118
-
(1992)
Science
, vol.258
, pp. 1112-1118
-
-
Peliska, J.A.1
Benkovic, S.J.2
-
37
-
-
0028349914
-
Fidelity of in vitro DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase
-
Peliska JA, Benkovic SJ (1994) Fidelity of in vitro DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase. Biochemistry 33:3890-3895
-
(1994)
Biochemistry
, vol.33
, pp. 3890-3895
-
-
Peliska, J.A.1
Benkovic, S.J.2
-
38
-
-
0029993627
-
Differences in mutagenesis during minus strand, plus strand and strand transfer (recombination) synthesis of the HIV-1 nef gene in vitro
-
Wu W, Palaniappan C, Bambara RA, Fay PJ (1996) Differences in mutagenesis during minus strand, plus strand and strand transfer (recombination) synthesis of the HIV-1 nef gene in vitro. Nucleic Acids Res 24:1710-1718
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1710-1718
-
-
Wu, W.1
Palaniappan, C.2
Bambara, R.A.3
Fay, P.J.4
-
39
-
-
0028819607
-
Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation
-
Wu W, Blumberg BM, Fay PJ, Bambara RA (1995) Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation. J Biol Chem 270:325-332
-
(1995)
J Biol Chem
, vol.270
, pp. 325-332
-
-
Wu, W.1
Blumberg, B.M.2
Fay, P.J.3
Bambara, R.A.4
-
40
-
-
0028088986
-
Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends
-
Patel PH, Preston BD (1994) Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends. Proc Natl Acad Sci USA 91:549-553
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 549-553
-
-
Patel, P.H.1
Preston, B.D.2
-
41
-
-
0028874043
-
Retroviral recombination can lead to linkage of reverse transcriptase mutations that confer increased zidovudine resistance
-
Kellam P, Larder BA (1995) Retroviral recombination can lead to linkage of reverse transcriptase mutations that confer increased zidovudine resistance. J Virol 69:669-674
-
(1995)
J Virol
, vol.69
, pp. 669-674
-
-
Kellam, P.1
Larder, B.A.2
-
42
-
-
0029973141
-
Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure
-
Moutouh L, Corbeil J, Richman DD (1996) Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure. Proc Natl Acad Sci USA 93:6106-6111
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6106-6111
-
-
Moutouh, L.1
Corbeil, J.2
Richman, D.D.3
-
45
-
-
0028874048
-
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
-
Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M (1995) Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123-126
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
Neumann, A.U.2
Perelson, A.S.3
Chen, W.4
Leonard, J.M.5
Markowitz, M.6
-
46
-
-
0029967721
-
HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
-
Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD (1996) HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271:1582-1586
-
(1996)
Science
, vol.271
, pp. 1582-1586
-
-
Perelson, A.S.1
Neumann, A.U.2
Markowitz, M.3
Leonard, J.M.4
Ho, D.D.5
-
47
-
-
15844385082
-
Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection
-
Wolinsky SM, Korber BT, Neumann AU, Daniels M, Kunstman KJ, Whetsell AJ, Furtado MR, Cao Y, Ho DD, Safrit JT, Koup RA (1996) Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection. Science 272:537-542
-
(1996)
Science
, vol.272
, pp. 537-542
-
-
Wolinsky, S.M.1
Korber, B.T.2
Neumann, A.U.3
Daniels, M.4
Kunstman, K.J.5
Whetsell, A.J.6
Furtado, M.R.7
Cao, Y.8
Ho, D.D.9
Safrit, J.T.10
Koup, R.A.11
-
48
-
-
0028811974
-
Viral dynamics in human immunodeficiency virus type 1 infection
-
Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, Deutsch P, Lifson JD, Bonhoeffer S, Nowak MA, Hahn BH, Saag MS, Shaw GM (1995) Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373:117-122
-
(1995)
Nature
, vol.373
, pp. 117-122
-
-
Wei, X.1
Ghosh, S.K.2
Taylor, M.E.3
Johnson, V.A.4
Emini, E.A.5
Deutsch, P.6
Lifson, J.D.7
Bonhoeffer, S.8
Nowak, M.A.9
Hahn, B.H.10
Saag, M.S.11
Shaw, G.M.12
-
49
-
-
0028952146
-
HIV population dynamics in vivo: Implications for genetic variation, pathogenesis and therapy
-
Coffin JM (1995) HIV population dynamics in vivo: implications for genetic variation, pathogenesis and therapy. Science 267:483-489
-
(1995)
Science
, vol.267
, pp. 483-489
-
-
Coffin, J.M.1
-
50
-
-
0026786637
-
Nonhomogeneous distribution of human immunodeficiency virus type 1 proviruses in the spleen
-
Delassus S, Cheynier R, Wain-Hobson S (1992) Nonhomogeneous distribution of human immunodeficiency virus type 1 proviruses in the spleen. J Virol 66:5642-5645
-
(1992)
J Virol
, vol.66
, pp. 5642-5645
-
-
Delassus, S.1
Cheynier, R.2
Wain-Hobson, S.3
-
51
-
-
0027959373
-
HIV and T cell expansion in splenic white pulps is accompanied by infiltration of HIV-specific cytotoxic T lymphocytes
-
Cheynier R, Henrichwark S, Hadida F, Pelletier E, Oksenhendler E, Autran B, Wain-Hobson S (1994) HIV and T cell expansion in splenic white pulps is accompanied by infiltration of HIV-specific cytotoxic T lymphocytes. Cell 78:373-387
-
(1994)
Cell
, vol.78
, pp. 373-387
-
-
Cheynier, R.1
Henrichwark, S.2
Hadida, F.3
Pelletier, E.4
Oksenhendler, E.5
Autran, B.6
Wain-Hobson, S.7
-
52
-
-
0029025631
-
Clonal expansion of T cells and HIV genotypes in microdissected splenic white pulps indicates viral replication in situ and infiltration of HIV-specifrc cytotoxic T lymphocytes
-
Cheynier R, Henrichwark S, Hadida F, Pelletier E, Oksenhendler E, Autran B, Wain-Hobson S (1995) Clonal expansion of T cells and HIV genotypes in microdissected splenic white pulps indicates viral replication in situ and infiltration of HIV-specifrc cytotoxic T lymphocytes. Adv Exp Med Biol 374:173-182
-
(1995)
Adv Exp Med Biol
, vol.374
, pp. 173-182
-
-
Cheynier, R.1
Henrichwark, S.2
Hadida, F.3
Pelletier, E.4
Oksenhendler, E.5
Autran, B.6
Wain-Hobson, S.7
-
53
-
-
0026600926
-
Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus populations
-
Schuitemaker H, Koot M, Kootstra NA, Dercksen MW, de Goude REY, van Steenwijk RP, Lange JMA, Eeftink Schattenkerk JKM, Miedema F, Tersmette M (1992) Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus populations. J Virol 66:1354-1360
-
(1992)
J Virol
, vol.66
, pp. 1354-1360
-
-
Schuitemaker, H.1
Koot, M.2
Kootstra, N.A.3
Dercksen, M.W.4
De Goude, R.E.Y.5
Van Steenwijk, R.P.6
Lange, J.M.A.7
Eeftink Schattenkerk, J.K.M.8
Miedema, F.9
Tersmette, M.10
-
54
-
-
0024536114
-
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome obtained from studies on a panel of sequential HIV isolates
-
Tersmette M, Gruters RA, De Wolf F, de Goede REY, Lange JMA, Schellekens PTA, Goudsmit J, Huisman JG, Miedema F (1989) Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome obtained from studies on a panel of sequential HIV isolates. J Virol 63:2118-2125
-
(1989)
J Virol
, vol.63
, pp. 2118-2125
-
-
Tersmette, M.1
Gruters, R.A.2
De Wolf, F.3
De Goede, R.E.Y.4
Lange, J.M.A.5
Schellekens, P.T.A.6
Goudsmit, J.7
Huisman, J.G.8
Miedema, F.9
-
56
-
-
0027366231
-
Immune escape by human immunodeficiency virus type 1 from neutralizing antibodies: Evidence for multiple pathways
-
Watkins BA, Reitz MSJ, Wilson CA, Aldrich K, Davis AE, Robert-Guroff M (1993) Immune escape by human immunodeficiency virus type 1 from neutralizing antibodies: evidence for multiple pathways. J Virol 67:7493-7500
-
(1993)
J Virol
, vol.67
, pp. 7493-7500
-
-
Watkins, B.A.1
Reitz, M.S.J.2
Wilson, C.A.3
Aldrich, K.4
Davis, A.E.5
Robert-Guroff, M.6
-
57
-
-
0024810615
-
Characterization of HIV-1 neutralization escape mutants
-
McKeating JA, Gow J, Goudsmit J, Pearl LH, Mulder C, Weiss RA (1989) Characterization of HIV-1 neutralization escape mutants. AIDS 3:777-784
-
(1989)
AIDS
, vol.3
, pp. 777-784
-
-
McKeating, J.A.1
Gow, J.2
Goudsmit, J.3
Pearl, L.H.4
Mulder, C.5
Weiss, R.A.6
-
58
-
-
0026544650
-
Autologous HIV-1 neutralizing antibodies: Emergence of neutralization-resistant escape virus and subsequent development of escape virus neutralizing antibodies
-
Arendrup M, Nielsen C, Hansen JE, Pedersen C, Mathiesen L, Nielsen JO (1992) Autologous HIV-1 neutralizing antibodies: emergence of neutralization-resistant escape virus and subsequent development of escape virus neutralizing antibodies. J AIDS 5:303-307
-
(1992)
J AIDS
, vol.5
, pp. 303-307
-
-
Arendrup, M.1
Nielsen, C.2
Hansen, J.E.3
Pedersen, C.4
Mathiesen, L.5
Nielsen, J.O.6
-
59
-
-
0026486570
-
Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody
-
Gorny MK, Conley AJ, Karwowska S, Buchbinder A, Xu JY, Emini EA, Koenig S, Zolla-Pazner S (1992) Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody. J Virol 66:7538-7542
-
(1992)
J Virol
, vol.66
, pp. 7538-7542
-
-
Gorny, M.K.1
Conley, A.J.2
Karwowska, S.3
Buchbinder, A.4
Xu, J.Y.5
Emini, E.A.6
Koenig, S.7
Zolla-Pazner, S.8
-
60
-
-
0026595148
-
Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120
-
Fung MS, Sun CR, Gordon WL, Liou RS, Chang TW, Sun WN, Daar ES, Ho DD (1992) Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120. J Virol 66:848-856
-
(1992)
J Virol
, vol.66
, pp. 848-856
-
-
Fung, M.S.1
Sun, C.R.2
Gordon, W.L.3
Liou, R.S.4
Chang, T.W.5
Sun, W.N.6
Daar, E.S.7
Ho, D.D.8
-
61
-
-
0343682656
-
Group-specific, major histocompatibility complex class !-restricted cytotoxic responses to human immunodeficiency virus 1 (HIV-1) envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual
-
Koenig S, Earl P, Powell D, Pantaleo G, Merli S, Moss B, Fauci AS (1988) Group-specific, major histocompatibility complex class !-restricted cytotoxic responses to human immunodeficiency virus 1 (HIV-1) envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual. Proc Natl Acad Sci USA 85:8638-8642
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8638-8642
-
-
Koenig, S.1
Earl, P.2
Powell, D.3
Pantaleo, G.4
Merli, S.5
Moss, B.6
Fauci, A.S.7
-
62
-
-
0023814638
-
T cells can present antigens such as HIV gp120 targeted to their own surface molecules
-
Lanzavecchia A, Roosnek E, Gregory T, Berman P, Abrignani S (1988) T cells can present antigens such as HIV gp120 targeted to their own surface molecules. Nature 334:530-532
-
(1988)
Nature
, vol.334
, pp. 530-532
-
-
Lanzavecchia, A.1
Roosnek, E.2
Gregory, T.3
Berman, P.4
Abrignani, S.5
-
63
-
-
0026597418
-
The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism
-
Cann AJ, Churcher MJ, Boyd M, O'Brien W, Zhuo J-Q, Zack J, Chen I SY (1992) The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. J Virol 66:305-309
-
(1992)
J Virol
, vol.66
, pp. 305-309
-
-
Cann, A.J.1
Churcher, M.J.2
Boyd, M.3
O'Brien, W.4
Zhuo, J.-Q.5
Zack, J.6
Chen, I.S.Y.7
-
64
-
-
0025783669
-
Identification of envelope V3 loop as the primary determinant of cell tropism in HIV-1
-
Hwang SS, Boyle TJ, Lyerly HK, Cullen BR (1991) Identification of envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253:71-74
-
(1991)
Science
, vol.253
, pp. 71-74
-
-
Hwang, S.S.1
Boyle, T.J.2
Lyerly, H.K.3
Cullen, B.R.4
-
65
-
-
0028969743
-
Change in tropism upon immune escape by human immunodeficiency virus
-
McKnight A, Weiss RA, Shotton C, Takeuchi Y, Hoshino H, Clapham PR (1995) Change in tropism upon immune escape by human immunodeficiency virus. J Virol 69:3167-3170
-
(1995)
J Virol
, vol.69
, pp. 3167-3170
-
-
McKnight, A.1
Weiss, R.A.2
Shotton, C.3
Takeuchi, Y.4
Hoshino, H.5
Clapham, P.R.6
-
67
-
-
0029926056
-
Reduced sensitivity to saquinavir: An update on genotyping from phase I/II trials
-
Jacobsen H, Haenggi M, Ott M, Duncan IB, Andreoni M, Vella S, Mous J (1996) Reduced sensitivity to saquinavir: an update on genotyping from phase I/II trials. Antiviral Res 29:95-97
-
(1996)
Antiviral Res
, vol.29
, pp. 95-97
-
-
Jacobsen, H.1
Haenggi, M.2
Ott, M.3
Duncan, I.B.4
Andreoni, M.5
Vella, S.6
Mous, J.7
-
68
-
-
15444377672
-
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
-
Molla A, Korneyeva M, Gao Q, Vasavanonda S, Schipper PJ, Mo HM, Markowitz M, Chernyavskiy T, Niu P, Lyons N, Hsu A, Granneman GR, Ho DD, Boucher CA, Leonard JM, Norbeck DW, Kempf DJ (1996) Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nat Med 2:760-766
-
(1996)
Nat Med
, vol.2
, pp. 760-766
-
-
Molla, A.1
Korneyeva, M.2
Gao, Q.3
Vasavanonda, S.4
Schipper, P.J.5
Mo, H.M.6
Markowitz, M.7
Chernyavskiy, T.8
Niu, P.9
Lyons, N.10
Hsu, A.11
Granneman, G.R.12
Ho, D.D.13
Boucher, C.A.14
Leonard, J.M.15
Norbeck, D.W.16
Kempf, D.J.17
-
69
-
-
0029866556
-
Combination therapy in primary HIV infection
-
Perrin L, Hirschel B (1996) Combination therapy in primary HIV infection. Antiviral Res 29:87-89
-
(1996)
Antiviral Res
, vol.29
, pp. 87-89
-
-
Perrin, L.1
Hirschel, B.2
-
70
-
-
0029984359
-
Combination therapy for HIV-1 infection-overview: Preclinical and clinical analysis of antiretroviral combinations
-
Johnson VA (1996) Combination therapy for HIV-1 infection-overview: preclinical and clinical analysis of antiretroviral combinations. Antiviral Res 29:35-39
-
(1996)
Antiviral Res
, vol.29
, pp. 35-39
-
-
Johnson, V.A.1
-
71
-
-
0029864682
-
Combination therapy with zidovudine, didanosine and saquinavir
-
Collier AC, Coombs RW, Schoenfeld DA, Bassett R, Baruch A, Corey L (1996) Combination therapy with zidovudine, didanosine and saquinavir. Antiviral Res 29:99
-
(1996)
Antiviral Res
, vol.29
, pp. 99
-
-
Collier, A.C.1
Coombs, R.W.2
Schoenfeld, D.A.3
Bassett, R.4
Baruch, A.5
Corey, L.6
-
72
-
-
2442723342
-
Treatment of human immunodeficiency virus infection (HIV) with saquinavir, zidovudine and zalcilabine. AIDS Clinical Trials Group
-
Collier AC, Coombs RW, Schoenfeld DA, Bassett RL, Timpone J, Baruch A, Jones M, Facey K, Whitacre C, McAuliffe VJ, Friedman HM, Merigan TC, Reichman RC, Hooper C, Corey L (1996) Treatment of human immunodeficiency virus infection (HIV) with saquinavir, zidovudine and zalcilabine. AIDS Clinical Trials Group. N Engl J Med 334:1011-1017
-
(1996)
N Engl J Med
, vol.334
, pp. 1011-1017
-
-
Collier, A.C.1
Coombs, R.W.2
Schoenfeld, D.A.3
Bassett, R.L.4
Timpone, J.5
Baruch, A.6
Jones, M.7
Facey, K.8
Whitacre, C.9
McAuliffe, V.J.10
Friedman, H.M.11
Merigan, T.C.12
Reichman, R.C.13
Hooper, C.14
Corey, L.15
-
73
-
-
0029148848
-
Can the immune response control HIV infection?
-
Paul WE (1995) Can the immune response control HIV infection? Cell 82:177-182
-
(1995)
Cell
, vol.82
, pp. 177-182
-
-
Paul, W.E.1
-
74
-
-
0030593031
-
Toward an understanding of the correlates of protective immunity to HIV infection
-
Haynes BF, Pantaleo G, Fauci AS (1996) Toward an understanding of the correlates of protective immunity to HIV infection. Science 271:324-328
-
(1996)
Science
, vol.271
, pp. 324-328
-
-
Haynes, B.F.1
Pantaleo, G.2
Fauci, A.S.3
-
75
-
-
0029803480
-
HIV viral dynamics
-
Coffin JM (1996) HIV viral dynamics. AIDS 10 [Suppl 3]:S75-S84
-
(1996)
AIDS
, vol.10
, Issue.3 SUPPL.
-
-
Coffin, J.M.1
-
76
-
-
7344224839
-
Four-drug combination: Effect of viral load and immune reconstitution (blood and lymph nodes)
-
Washington, abstract 235
-
Lafeuillade A, Tamalet C, Poogi C, Kaplanski, Chouraqui M, Delbeke E, Profizi N, Kaplanski S, Farnarier C (1997) Four-drug combination: effect of viral load and immune reconstitution (blood and lymph nodes). 4th Conference on Retroviruses and Opportunistic Infections, Washington, abstract 235
-
(1997)
4th Conference on Retroviruses and Opportunistic Infections
-
-
Lafeuillade, A.1
Tamalet, C.2
Poogi, C.3
Kaplanski4
Chouraqui, M.5
Delbeke, E.6
Profizi, N.7
Kaplanski, S.8
Farnarier, C.9
-
77
-
-
7344236741
-
MRL acute HIV infection study Group. An open treatment study of acute HIV infection with zidovudine, lamivudine and indinavir sulfate
-
Washington, abstract 238
-
Perrin L, Markowitz M, Calandra G, Chung M (1997) MRL acute HIV infection study Group. An open treatment study of acute HIV infection with zidovudine, lamivudine and indinavir sulfate. 4th Conference on Retroviruses and Opportunistic Infections, Washington, abstract 238
-
(1997)
4th Conference on Retroviruses and Opportunistic Infections
-
-
Perrin, L.1
Markowitz, M.2
Calandra, G.3
Chung, M.4
-
78
-
-
7344219767
-
Neutralizing antibody directed against the V3 loop selects for different escape variants in M184V-containing virus compared with wild type HIV-1
-
25-28 June, St. Petersburg, Florida, abstract 118
-
Inouye P, Zolfa-Pazner S, Wainberg MA (1997) Neutralizing antibody directed against the V3 loop selects for different escape variants in M184V-containing virus compared with wild type HIV-1. International Workshop on HIV Drug Resistance, Treatment Strategies and Eradication, 25-28 June, St. Petersburg, Florida, abstract 118
-
(1997)
International Workshop on HIV Drug Resistance, Treatment Strategies and Eradication
-
-
Inouye, P.1
Zolfa-Pazner, S.2
Wainberg, M.A.3
-
79
-
-
0030791104
-
Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase
-
Oude Essink BB, Back NKT, Berkhout B (1997) Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase. Nucleic Acids Res 25:3212-3217
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3212-3217
-
-
Oude Essink, B.B.1
Back, N.K.T.2
Berkhout, B.3
-
80
-
-
0030772853
-
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1
-
Hsu M, Inouye P, Rezende L, Richard N, Li Z, Prasad VR, Wainberg MA (1997) Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Res 25:4532-4536
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4532-4536
-
-
Hsu, M.1
Inouye, P.2
Rezende, L.3
Richard, N.4
Li, Z.5
Prasad, V.R.6
Wainberg, M.A.7
-
81
-
-
0029028067
-
Potential mechanism for sustained anti-retroviral efficacy of 3TC-AZT combination therapy
-
Larder BA, Kemp SD, Harrigan PR (1995) Potential mechanism for sustained anti-retroviral efficacy of 3TC-AZT combination therapy. Science 269:696-699
-
(1995)
Science
, vol.269
, pp. 696-699
-
-
Larder, B.A.1
Kemp, S.D.2
Harrigan, P.R.3
-
82
-
-
0029563673
-
Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter
-
Eron JJ, Benoit SL, Jemsek J, Mac-Arthur RD, Santana J, Quinn JB, Kuritzkes DR, Fallon MA, Rubin M, North American HIV Working Party (1995) Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. N Engl J Med 333:1662-1669
-
(1995)
N Engl J Med
, vol.333
, pp. 1662-1669
-
-
Eron, J.J.1
Benoit, S.L.2
Jemsek, J.3
Mac-Arthur, R.D.4
Santana, J.5
Quinn, J.B.6
Kuritzkes, D.R.7
Fallon, M.A.8
Rubin, M.9
-
83
-
-
9444290697
-
Virologie and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy
-
Schooley RT, Ramirez-Ronda C, Lange JM, Cooper DA, Lavelle J, Lefkowitz L, Moore M, Larder BA, St. Clair M, Mulder JW, McKinnis R, Pennington KN, Harrigan PR, Kinghorn I, Steel H, Rooney JF, Wellcome Resistance Study Collaborative Group (1996) Virologie and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy. J Infect Dis 173:1354-1366
-
(1996)
J Infect Dis
, vol.173
, pp. 1354-1366
-
-
Schooley, R.T.1
Ramirez-Ronda, C.2
Lange, J.M.3
Cooper, D.A.4
Lavelle, J.5
Lefkowitz, L.6
Moore, M.7
Larder, B.A.8
St. Clair, M.9
Mulder, J.W.10
McKinnis, R.11
Pennington, K.N.12
Harrigan, P.R.13
Kinghorn, I.14
Steel, H.15
Rooney, J.F.16
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