-
2
-
-
0026579998
-
The mucosal immune system: From fundamental concepts to vaccine development
-
McGhee JR, Mestecky J, Dertzbaugh MT et al. The mucosal immune system: From fundamental concepts to vaccine development. Vaccine 1992; 10: 75-88.
-
(1992)
Vaccine
, vol.10
, pp. 75-88
-
-
McGhee, J.R.1
Mestecky, J.2
Dertzbaugh, M.T.3
-
3
-
-
0010687078
-
A molecular approach to the construction of an effective mucosal vaccine adjuvant. Studies based on cholera toxin ADP-ribosylation and cell targeting
-
Kagnoff MF, Kiyono H (eds) Academic Press
-
Lycke N. A molecular approach to the construction of an effective mucosal vaccine adjuvant. Studies based on cholera toxin ADP-ribosylation and cell targeting. In: Kagnoff MF, Kiyono H (eds) Essentials of Mucosal Immunology. Academic Press, 1996; 563-80.
-
(1996)
Essentials of Mucosal Immunology
, pp. 563-580
-
-
Lycke, N.1
-
4
-
-
0002160869
-
Mucosal adjuvants
-
Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JR, Bienenstock J (eds) Academic Press
-
Elson CO, Dertzbaugh MT. Mucosal adjuvants. In: Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JR, Bienenstock J (eds) Handbook of Mucosal Immunology. Academic Press, 1994; 391-402.
-
(1994)
Handbook of Mucosal Immunology.
, pp. 391-402
-
-
Elson, C.O.1
Dertzbaugh, M.T.2
-
5
-
-
0343773445
-
IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease
-
Röcken M, Racke M, Shevach EM. IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease. Immunol. Today 1996; 17: 225-31.
-
(1996)
Immunol. Today
, vol.17
, pp. 225-231
-
-
Röcken, M.1
Racke, M.2
Shevach, E.M.3
-
6
-
-
0002000895
-
Oral tolerance and regulation of immunity to dietary antigens
-
Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JP, Bienenstock J (eds) Academic Press
-
Mowat A. Oral tolerance and regulation of immunity to dietary antigens. In: Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JP, Bienenstock J (eds) Handbook of Mucosal Immunology. Academic Press, 1994; 185.
-
(1994)
Handbook of Mucosal Immunology
, pp. 185
-
-
Mowat, A.1
-
7
-
-
0002044169
-
Oral tolerance: Immunologic mechanisms and treatment of autoimmune diseases
-
Kagnoff MF, Kiyono H (eds) Academic Press
-
Weiner HL. Oral tolerance: Immunologic mechanisms and treatment of autoimmune diseases. In: Kagnoff MF, Kiyono H (eds) Essentials of Mucosal Immunology. Academic Press, 1996; 555-61.
-
(1996)
Essentials of Mucosal Immunology.
, pp. 555-561
-
-
Weiner, H.L.1
-
8
-
-
0025806703
-
Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route
-
Mowat AM, Donachie AM, Reid G, Jarrett O. Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology 1991; 72: 317-22.
-
(1991)
Immunology
, vol.72
, pp. 317-322
-
-
Mowat, A.M.1
Donachie, A.M.2
Reid, G.3
Jarrett, O.4
-
9
-
-
0025834747
-
Biodegradable and biocompatible poly (DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies
-
Eldridge JH, Staas JK, Meulbroek JA, Tice TR, Gilley RM. Biodegradable and biocompatible poly (DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect. Immun. 1991; 59: 2978-86.
-
(1991)
Infect. Immun.
, vol.59
, pp. 2978-2986
-
-
Eldridge, J.H.1
Staas, J.K.2
Meulbroek, J.A.3
Tice, T.R.4
Gilley, R.M.5
-
10
-
-
2642676876
-
Lack of local suppression in orally tolerant CD8 deficient mice reveals a critical regulatory role of CD8+ T cells in the normal gut mucosa
-
Grdic D, Hörnquist E, Kjerrulf M, Lycke N. Lack of local suppression in orally tolerant CD8 deficient mice reveals a critical regulatory role of CD8+ T cells in the normal gut mucosa. J. Immunol. 1998; 160: 754-62.
-
(1998)
J. Immunol.
, vol.160
, pp. 754-762
-
-
Grdic, D.1
Hörnquist, E.2
Kjerrulf, M.3
Lycke, N.4
-
11
-
-
0021681145
-
Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen
-
Elson CO, Ealding W. Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen. J. Immunol. 1984; 133: 2892-7.
-
(1984)
J. Immunol.
, vol.133
, pp. 2892-2897
-
-
Elson, C.O.1
Ealding, W.2
-
12
-
-
0029161099
-
The three-dimensional crystal structure of cholera toxin
-
Zhang RG, Scott DL, Westbrook ML et al. The three-dimensional crystal structure of cholera toxin. J. Mol. Biol. 1995; 251: 563-73.
-
(1995)
J. Mol. Biol.
, vol.251
, pp. 563-573
-
-
Zhang, R.G.1
Scott, D.L.2
Westbrook, M.L.3
-
13
-
-
0027942083
-
Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis
-
Pizza M, Domenighini M, Hol W et al. Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis. Mol. Microbiol. 1994; 14: 51-60.
-
(1994)
Mol. Microbiol.
, vol.14
, pp. 51-60
-
-
Pizza, M.1
Domenighini, M.2
Hol, W.3
-
14
-
-
0026458260
-
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
-
Spangler BD. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol. Rev. 1992; 56: 622-47.
-
(1992)
Microbiol. Rev.
, vol.56
, pp. 622-647
-
-
Spangler, B.D.1
-
16
-
-
19144364760
-
Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin
-
Takahashi I, Marinaro M, Kiyono H et al. Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. J. Infect. Dis. 1996; 173: 627-35.
-
(1996)
J. Infect. Dis.
, vol.173
, pp. 627-635
-
-
Takahashi, I.1
Marinaro, M.2
Kiyono, H.3
-
17
-
-
0030940814
-
Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin
-
Douce G, Fontana M, Pizza M, Rappuoli R, Dougan G. Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin. Infect. Immun. 1997; 65: 2821-8.
-
(1997)
Infect. Immun.
, vol.65
, pp. 2821-2828
-
-
Douce, G.1
Fontana, M.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
-
18
-
-
0027174854
-
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin
-
Sixma TK, Kalk KH, van Zanten BA et al. Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin. J. Mol. Biol. 1993; 230: 890-918.
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 890-918
-
-
Sixma, T.K.1
Kalk, K.H.2
Van Zanten, B.A.3
-
19
-
-
0019293278
-
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin
-
Dallas WS, Falkow S. Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin. Nature 1980; 288: 499-501.
-
(1980)
Nature
, vol.288
, pp. 499-501
-
-
Dallas, W.S.1
Falkow, S.2
-
20
-
-
0030030530
-
Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: Receptor binding is essential and induces differential modulation of lymphocyte subsets
-
Nashar TO, Webb HM, Eaglestone S, Williams NA, Hirst TR. Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: Receptor binding is essential and induces differential modulation of lymphocyte subsets. Proc. Natl Acad. Sci. USA 1996; 93: 226-30.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 226-230
-
-
Nashar, T.O.1
Webb, H.M.2
Eaglestone, S.3
Williams, N.A.4
Hirst, T.R.5
-
21
-
-
0029094081
-
Analysis of the second messenger systems involved in the synergistic effect of cholera toxin and interleukin-4 on B cell isotype-switching
-
Lycke N. Analysis of the second messenger systems involved in the synergistic effect of cholera toxin and interleukin-4 on B cell isotype-switching. Adv. Exp. Med. Biol. 1995; 15-20.
-
(1995)
Adv. Exp. Med. Biol.
, pp. 15-20
-
-
Lycke, N.1
-
22
-
-
0028906467
-
Impaired mucosal immune responses in interleukin 4-targeted mice
-
Vajdy M, Kosco-Vilbois M, Kopf M, Köhler G, Lycke N. Impaired mucosal immune responses in interleukin 4-targeted mice. J. Exp. Med. 1995; 181: 41-53.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 41-53
-
-
Vajdy, M.1
Kosco-Vilbois, M.2
Kopf, M.3
Köhler, G.4
Lycke, N.5
-
23
-
-
0030820364
-
Interferon-γ deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance
-
Kjerrulf M, Grdic D, Ekman L et al. Interferon-γ deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance. Immunology 1997; 92: 60-8.
-
(1997)
Immunology
, vol.92
, pp. 60-68
-
-
Kjerrulf, M.1
Grdic, D.2
Ekman, L.3
-
24
-
-
0030023828
-
CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effect of cholera toxin
-
Hörnquist E, Grdic D, Mak T, Lycke N. CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effect of cholera toxin. Immunology 1996; 87: 220-9.
-
(1996)
Immunology
, vol.87
, pp. 220-229
-
-
Hörnquist, E.1
Grdic, D.2
Mak, T.3
Lycke, N.4
-
25
-
-
0031569528
-
A genetically engineered non-toxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit
-
Ågren L, Ekman L, Löwenadler B, Lycke N. A genetically engineered non-toxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. J. Immunol. 1997; 158: 3936-46.
-
(1997)
J. Immunol.
, vol.158
, pp. 3936-3946
-
-
Ågren, L.1
Ekman, L.2
Löwenadler, B.3
Lycke, N.4
-
27
-
-
0026699224
-
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity
-
Lycke N, Tsuji T, Holmgren J. The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol. 1992; 22: 2277-81.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2277-2281
-
-
Lycke, N.1
Tsuji, T.2
Holmgren, J.3
-
28
-
-
0024322169
-
Cholera toxin as a mucosal adjuvant: Glutaraldehyde treatment dissociates adjuvanticity from toxicity
-
Liang X, Lamm ME, Nedrud JG. Cholera toxin as a mucosal adjuvant: Glutaraldehyde treatment dissociates adjuvanticity from toxicity. J. Immunol. 1989; 143: 484-90.
-
(1989)
J. Immunol.
, vol.143
, pp. 484-490
-
-
Liang, X.1
Lamm, M.E.2
Nedrud, J.G.3
-
29
-
-
0021058990
-
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
-
Levine MM, Kaper JB, Black RE, Clemens ML. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev. 1983; 47: 510-50.
-
(1983)
Microbiol. Rev.
, vol.47
, pp. 510-550
-
-
Levine, M.M.1
Kaper, J.B.2
Black, R.E.3
Clemens, M.L.4
-
30
-
-
0027488503
-
The interaction between different domains of staphylococcal protein A and human polyclonal IgG, IgA, IgM and F (ab′)2: Separation of affinity from specificity
-
Ljungberg UK, Jansson B, Niss U et al. The interaction between different domains of staphylococcal protein A and human polyclonal IgG, IgA, IgM and F (ab′)2: Separation of affinity from specificity. Mol. Immunol. 1993; 30: 1279-85.
-
(1993)
Mol. Immunol.
, vol.30
, pp. 1279-1285
-
-
Ljungberg, U.K.1
Jansson, B.2
Niss, U.3
-
31
-
-
0028141008
-
Fusion proteins with heterologous T helper epitopes. Recombinant E. coli heat-stable enterotoxin proteins
-
Löwenadler B, Lycke N. Fusion proteins with heterologous T helper epitopes. Recombinant E. coli heat-stable enterotoxin proteins. Intern. Rev. Immunol. 1994; 11: 103-11.
-
(1994)
Intern. Rev. Immunol.
, vol.11
, pp. 103-111
-
-
Lycke N, L.B.1
-
32
-
-
0028113922
-
A quantitative analysis of antigen-presenting cell function; activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing co-stimulation
-
Cassell DJ, Schwartz RH. A quantitative analysis of antigen-presenting cell function; activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing co-stimulation. J. Exp. Med. 1994; 180: 1829-40.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1829-1840
-
-
Cassell, D.J.1
Schwartz, R.H.2
-
33
-
-
0029157151
-
B lymphocytes can be competent antigen presenting cells for priming CD4+ T cells to protein antigens in vivo
-
Constant S, Schweitzer N, West J, Ranney P, Bottomly K. B lymphocytes can be competent antigen presenting cells for priming CD4+ T cells to protein antigens in vivo. J. Immunol. 1995; 155: 3734-41.
-
(1995)
J. Immunol.
, vol.155
, pp. 3734-3741
-
-
Constant, S.1
Schweitzer, N.2
West, J.3
Ranney, P.4
Bottomly, K.5
-
35
-
-
0031296660
-
The mucosal adjuvanticity of cholera toxin involves enhancement of co-stimulatory activity by selective up-regulation of B7.2 expression
-
Cong Y, Weaver C, Elson C. The mucosal adjuvanticity of cholera toxin involves enhancement of co-stimulatory activity by selective up-regulation of B7.2 expression. J. Immunol. 1997; 159: 5301.
-
(1997)
J. Immunol.
, vol.159
, pp. 5301
-
-
Cong, Y.1
Weaver, C.2
Elson, C.3
-
36
-
-
0029041926
-
cAmp-independent effects of cholera toxin on B cell activation, Iii. Cholera toxin a subunit-mediated ADP-ribosylation acts synergistically with ionomycin or IL-4 to induce B cell proliferation
-
Francis ML, Okazaki I, Moss J et al. cAmp-independent effects of cholera toxin on B cell activation, Iii. Cholera toxin a subunit-mediated ADP-ribosylation acts synergistically with ionomycin or IL-4 to induce B cell proliferation. J. Immunol. 1995; 154: 4956-64.
-
(1995)
J. Immunol.
, vol.154
, pp. 4956-4964
-
-
Francis, M.L.1
Okazaki, I.2
Moss, J.3
-
37
-
-
0028985871
-
Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
-
Dickinson BL, Clements JD. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 1995; 63: 1617-23.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1617-1623
-
-
Dickinson, B.L.1
Clements, J.D.2
-
38
-
-
0028918767
-
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants
-
Douce G, Turcotte C, Cropley I et al. Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. Proc. Natl Acad. Sci. USA 1995; 92: 1644-8.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1644-1648
-
-
Douce, G.1
Turcotte, C.2
Cropley, I.3
-
39
-
-
0029805948
-
Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin
-
de Haan L, Verweij WR, Feil IK et al. Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin. Infect. Immun. 1996; 64: 5413-16.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5413-5416
-
-
De Haan, L.1
Verweij, W.R.2
Feil, I.K.3
-
40
-
-
0007205169
-
A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
-
Yamamoto S, Kiyono H, Yamamoto M et al. A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc. Natl Acad. Sci. USA 1997; 94; 5267-72.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 5267-5272
-
-
Yamamoto, S.1
Kiyono, H.2
Yamamoto, M.3
-
41
-
-
0030902280
-
Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrhea-genicity but retain adjuvanticity
-
Yamamoto S, Takeda Y, Yamamoto M et al. Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrhea-genicity but retain adjuvanticity. J. Exp. Med. 1997; 185: 1203-10.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1203-1210
-
-
Yamamoto, S.1
Takeda, Y.2
Yamamoto, M.3
-
42
-
-
0026005836
-
Site-specific mutagenesis of the catalytic subunit of cholera toxin: Substituting lysine for arginine 7 causes loss of activity
-
Burnette WN, Mar VL, Platler BW et al. Site-specific mutagenesis of the catalytic subunit of cholera toxin: Substituting lysine for arginine 7 causes loss of activity. Infect. Immun. 1991; 59: 4266-70.
-
(1991)
Infect. Immun.
, vol.59
, pp. 4266-4270
-
-
Burnette, W.N.1
Mar, V.L.2
Platler, B.W.3
-
43
-
-
0028128355
-
Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin
-
Grant CC, Messer RJ, Cieplak W Jr. Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin. Infect. Immun. 1994; 62: 4270-8.
-
(1994)
Infect. Immun.
, vol.62
, pp. 4270-4278
-
-
Grant, C.C.1
Messer, R.J.2
Cieplak Jr., W.3
-
44
-
-
0029852233
-
Mutations in the a subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin
-
Magagnoli C, Manetti R, Fontana MR et al. Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin. Infect. Immun. 1996; 64: 5434-8.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5434-5438
-
-
Magagnoli, C.1
Manetti, R.2
Fontana, M.R.3
-
45
-
-
0027396382
-
Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit
-
Wu HY, Russell MW. Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit. Infect. Immun. 1993; 61: 314-20.
-
(1993)
Infect. Immun.
, vol.61
, pp. 314-320
-
-
Wu, H.Y.1
Russell, M.W.2
-
46
-
-
0029036648
-
Mucosal immunization with bacterial protein antigen genetically coupled to cholera toxin A2/B subunits
-
Hajishengallis G, Hollingshead SK, Koga T, Russell MW. Mucosal immunization with bacterial protein antigen genetically coupled to cholera toxin A2/B subunits. J. Immunol. 1995; 154: 4322-32.
-
(1995)
J. Immunol.
, vol.154
, pp. 4322-4332
-
-
Hajishengallis, G.1
Hollingshead, S.K.2
Koga, T.3
Russell, M.W.4
|