An essential role for retinoid signaling in anteroposterior neural patterning

Development

Volumn 124, Issue 2, 1997, Pages 373-379

  Blumberg, Bruce ^a   Bolado Jr , Jack ^a,b   Moreno, Tanya Ann ^a,d   Kintner, Chris ^a   Evans, Ronald M ^a,b   Papalopulu, Nancy ^c  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c WELLCOME CRC INSTITUTE   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

A P neural patterning; Dominant negative; RAR; Retinoid

Indexed keywords

RETINOIC ACID RECEPTOR; RETINOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR POSTERIOR AXIS; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; MARKER GENE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; ECTODERM; EMBRYO, NONMAMMALIAN; EMBRYONIC INDUCTION; GENES, REPORTER; IN SITU HYBRIDIZATION; MESODERM; MICROINJECTIONS; NERVOUS SYSTEM; NEURONS; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION; TRETINOIN; XENOPUS;

ANIMALIA; VERTEBRATA;

EID: 0031040737     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Blitz, I. L. and Cho, K. W. Y. (1995). Anterior neuroectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle. Development 121, 993-1004.
2. Blumberg, B., Mangelsdorf, D. J., Dyck, J., Bittner, D. A., Jegalian, K., Evans, R. M. and De Robertis, E. M. (1992). Multiple retinoid-responsive receptors in a single cell: families of RXRs and RARs in the Xenopus egg. Proc. Nat. Acad. Sci. USA 89, 2321-2325.
3. Blumberg, B., Bolado, J. Jr, Derguini, F., Craig, A. G., Moreno, T. A., Charkravarti, D., Heyman, R. A., Buck, J. and Evans, R. M. (1996). Novel RAR ligands in Xenopus embryos. Proc. Nat. Acad. Sci. USA 93, 4873-4878.
4. Bradley, L. C., Snape, A., Bhatt, S. and Wilkinson, D. G. (1993) The structure and expression of the Xenopus Krox-20 gene: conserved and divergent patterns of expression in rhombomeres and neural crest. Mech. Dev. 40, 73-84.
5. Bryant, S. V. and Gardiner, D. M. (1992). Retinoic acid, local cell-cell interactions and pattern formation in vertebrate limbs. Dev. Biol. 152, 1-25.
6. Chen, Y. P., Huang, L. and Solursh, M. (1994). A concentration gradient of retinoids in the early Xenopus laevis embryo. Dev. Biol. 161, 70-76.
7. Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D. and Kintner, C. (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.
8. Cho, K. W. Y., Blumberg, B., Steinbeisser, H. and De Robertis, E. M. (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.
9. Coffman, C. R., Skoglund, P., Harris, W. A. and Kintner, C. (1993). Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos. Cell 73, 659-671.
10. Conlon, R. A. and Rossant, J. (1992). Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development 116, 357-68.
11. Conlon, R. A. (1995). Retinoic acid and pattern formation in vertebrates. Trends Genet. 11, 314-319.
12. Cox, W. G. and Hemmati-Brivanlou, A. (1995). Caudalization of neural fate by tissue recombination and bFGF. Development 121, 4349-4358.
13. Damm, K., Heyman, R. A., Umesono, K. and Evans, R. M. (1993). Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants. Proc. Nat. Acad. Sci. USA 90, 2989-2993.
14. Dekker, E. J., Pannese, M., Houtzager, E., Boncinelli, E. and Durston, A. (1992). Colinearity in the Xenopus laevis Hox-2 complex. Mech. Dev. 40, 3-12.
15. Doniach, T. (1995). Basic FGF as an inducer of anteroposterior neural pattern. Cell 83, 1067-1070.
16. Drysdale, T, A. and Crawford, M. J. (1994). Effects of localized application of retinoic acid on Xenopus laevis development. Dev. Biol. 162, 394-401.
17. Durston, A. J., Timmermans, J. P., Hage, W. J., Hendriks, H. F., de Vries, N. J., Heideveld, M. and Nieuwkoop, P. D. (1989). Retinoic acid causes an anteroposterior transformation in the developing central nervous system. Nature 340, 140-144.
18. Ellinger-Ziegelbauer, H. and Dreyer, C. (1991). A retinoic acid receptor expressed in the early development of Xenopus laevis. Genes Dev. 5, 94-104.
19. Eyal-Giladi, H. (1954). Dynamic aspects of neural induction. Arch. Biol. 65, 180-259.
20. Gilbert, S. F. and Saxen, L. (1993). Spemann's organizer: models and molecules. Mech. Dev. 41, 73-89.
21. Harland, R. (1991). In situ hybridization: An improved whole-mount method for Xenopus embryos. Meth. Cell Biol. 36, 685-695.
22. Hawley, S. H., Wunnenberg-Stapleton, K., Hashimoto, C., Laurent, M. N., Watabe, T., Blumberg, B. and Cho, K. W. Y. (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct nerual induction. Genes Dev. 9, 2923-2935.
23. Hemmati-Brivanlou, A. and Harland, R. M. (1989). Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development 106, 611-617.
24. Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A. (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.
25. Hemmati-Brivanlou, A. and Melton, D. A. (1994). Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281.
26. Heyman, R. A., Mangelsdorf, D. J., Dyck, J. A., Stein, R. B., Eichele, G., Evans, R. M. and Thaller, C. (1992). 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68, 397-406.
27. Jones-Villeneuve, E. M. V., McBurney, M. W., Rogers, K. A. and Kalnins, V. I. (1982). Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J. Cell Biol. 94, 253-262.
28. Kastner, P., Mark, M. and Chambon, P. (1995). Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell 83, 859-869.
29. Kengaku, M. and Okamoto, H. (1995). bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus. Development 121, 3121-3130.
30. Kolm, P. J. and Sive, H. L. (1995). Regulation of the Xenopus labial homeodomain genes, HoxA1 and HoxD1: activation by retinoids and peptide growth factors. Dev. Biol. 167, 34-49.
31. Kroll, K. L. and Amaya, E. (1996). Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 122, 3173-3183.
32. Lamb, T. M., Knecht, A. K., Smith, W. C., Stachel, S. E., Economides, A. N., Stahl, N., Yancopolouos, G. D. and Harland, R. M. (1993). Neural induction by the secreted polypeptide noggin. Science 262, 713-718.
33. Lamb, T. M. and Harland, R. M. (1995). Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. Development 121, 3627-3636.
34. Levin, A. A., Sturzenbecker, L. J., Kazmer, S., Bosakowski, T., Huselton, C., Allenby, G., Speck, J., Kratzeisen, C., Rosenberger, J., Lovey, A. and Grippo, J. F. (1992). 9-cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRa. Nature 355, 359-361.
35. Maden, M. and Holder, N. (1992). Retinoic acid and development of the central nervous system. BioEssays 14, 431-438.
36. Maden, M., Gale, W., Kostetskii, I. and Zile, M. (1996). Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr. Biol. 6, 417-426.
37. Mangelsdorf, D. J., Umesono, K. and Evans, R. M. (1994). The retinoid receptors. In The Retinoids: Biology, Chemistry and Medicine, 2nd edn (ed. M. B. Sporn, A. B. Roberts and D. S. Goodman), pp. 319-349. Raven, New York, NY.
38. McBurney, M. W., Jones-Villeneuve, E. M. V., Edwards, M. K. S. and Anderson, P. J. (1982). Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature 299, 165-167.
39. Nieuwkoop, P. D. (1952). Activation and organization of the central nervous system in amphibians. Part III. synthesis of a new working hypothesis. J. Exp. Zool. 120, 83-108.
40. Nieuwkoop, P. O. and Faber, J. (1967). A Normal Table of Xenopus laevis (Daudin). North Holland, Amsterdam.
41. Papalopulu, N., Clarke, J. D. W., Bradley, L., Wilkinson, D., Krumlauf, R. and Holder, N. (1991a). Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos. Development 113, 1145-1158.
42. Papalopulu, N., Lovell-Badge, R. and Krumlauf, R. (1991b). The expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to retinoic acid in F9 cells and Xenopus embryos. Nucl. Acids Res. 19, 5497-5506.
43. Papalopulu, N. and Kintner, C. (1996). A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm. Development 122, 3409-3418.
44. Perlmann, T., Rangarajan, P. N., Umesono, K. and Evans, R. M. (1993). Determinants for selective RAR and TR recognition of direct repeat HREs. Genes Dev. 7, 1411-1422.
45. Pownall, M. E., Tucker, A. S., Slack, J. M. W. and Isaacs, H. V. (1996). eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus. Development 122, 3881-3892.
46. Ruiz i Altaba, A. and Jessell, T. (1991). Retinoic acid modifies mesodermal patterning in early Xenopus embryos. Genes Dev. 5, 175-187.
47. Sadowski, I., Ma, J., Triezenberg, S. and Ptashne, M. (1988). GAL4-VP16 is an unusually potent transcriptional activator. Nature 335, 563-564.
48. Sasai, Y., Lu, B., Steinbeisser, H. and De Robertis, E. M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
49. Schuh, T. J., Hall, B. L., Kraft, J. C., Privalsky, M. L. and Kimelman, D. (1993). v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryos. Development 119, 785-798.
50. Schuh, T. J. and Kimelman, D. (1995). COUP-TFI is a potential regulator of retinoic acid-modulated development in Xenopus embryos. Mech. Dev. 51, 39-49.
51. Sharpe, C. R. (1991). Retinoic acid can mimic endogenous signals involved in transformation of the Xenopus nervous system. Neuron 7, 239-247.
52. Sharpe, C. R. (1992). Two isoforms of retinoic acid receptor alpha expressed during Xenopus development respond to retinoic acid. Mech. Dev. 39, 81-93.
53. Sidell, N. (1982). Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro. J. Nat. Cancer Inst. 68, 589-593.
54. Simeone, A., Avantaggiato, V., Moroni, M. C., Mavilio, F., Arra, C., Cotelli, F., Nigro, V. and Acampora, D. (1995). Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system. Mech. Dev. 51, 83-98.
55. Sive, H. L., Draper, B. W., Harland, R. and Weintraub H. (1990) Identification of retinoic acid-sensitive period during primary axis formation in Xenopus laevis. Genes Dev. 4, 932-942.
56. Sive, H. L. and Cheng, P. F. (1991). Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis. Genes Dev. 5, 1321-1332.
57. Smith, D. P., Mason, C. S., Jones, E. and Old, R. (1994). Expression of a dominant negative retinoic acid receptor y in Xenopus embryos leads to partial resistance to retinoic acid. Roux's Arch. Dev. Biol. 203, 254-265.
58. Sporn, M. B., Roberts, A. B. and Goodman, D. S., eds (1994). The Retinoids: Biology, Chemistry and Medicine. 2nd edn. Raven, New York.
59. Taira, M., Jamrich, M., Good, P. J. and Dawid, I. B. (1992). The LIM domain-containing homeobox gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. Genes Dev. 6, 356-366.
60. Wright, C. V. E., Morita, E. A., Wilkin, D. J. and De Robertis, E. M. (1990). The Xenopus X1Hbox 6 homeoprotein, a marker of posterior neural induction, is expressed in proliferating neurons. Development 109, 225-234.