POU transcription factors control expression of CNS stem cell-specific genes

Development

Volumn 125, Issue 16, 1998, Pages 3087-3100

  Josephson, R ^a   Muller T ^a,c   Pickel, J ^a   Okabe, S ^a,d   Reynolds, K ^b   Turner, P A ^a   Zimmer, A ^b   McKay, R D G ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d NATL INST BIOSCI HUM TECHNOL   (Japan)

Author keywords

Brain fatty acid binding protein; Mouse; Nestin intermediate filament; Neuroepithelium; Precursor cell

Indexed keywords

FATTY ACID BINDING PROTEIN; NESTIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; ENHANCER REGION; FOREBRAIN; HORMONE RESPONSIVE ELEMENT; MESENCEPHALON; MOUSE; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM; DNA FOOTPRINTING; DNA MUTATIONAL ANALYSIS; ENHANCER ELEMENTS (GENETICS); FATTY ACID-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HISTOCYTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MYELIN P2 PROTEIN; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PROMOTER REGIONS (GENETICS); STEM CELLS; TRANSCRIPTION FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 0031667843     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Alvarez-Bolado, G., Rosenfeld, M. G. and Swanson, L. W. (1995). Model of forebrain regionalization based on spatiotemporal patterns of POU-III homeobox gene expression, birthdates, and morphological features. J. Comp. Neurol. 355, 237-295.
2. Andersen, B., Schonemann, M. D., Pearse, R. V. 2d., Jenne, K., Sugarman, J. and Rosenfeld, M. G. (1993). Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. J. Biol. Chem. 268, 23390-23398.
3. Baldwin, A. S. (1988). Methylation interference assay for analysis of DNA-protein interactions. In Current Protocols in Molecular Biology (ed. F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl), pp. 12.3.1-12.3.6. New York: John Wiley and Sons, Inc.
4. Bermingham, J. R., Jr., Scherer, S. S., O'Connell, S., Arroyo, E., Kalla, K. A., Powell, F. L. and Rosenfeld, M. G. (1996). Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev. 10, 1751-1762.
5. Bhat, K. M., Poole, S. J. and Schedl, P. (1995). The miti-mere and pdm1 genes collaborate during specification of the RP3/sib lineage in Drosophila neurogenesis. Mol. Cell. Biol. 15, 4052-4063.
6. Brüstle, O., Maskos, U. and McKay, R. D. G. (1995). Host-guided migration allows targeted introduction of neurons into the embryonic brain. Neuron 15, 1275-1285.
7. Budhram-Mahadeo, V., Parker, M. and Latchman, D. S. (1998). POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Mol. Cell. Biol. 18, 1029-1041.
8. Campbell, K., Olsson, M. and Björklund, A. (1995). Regional incorporation and site-specific differentiation of striatal precursors transplanted to the embryonic forebrain ventricle. Neuron 15, 1259-1273.
9. Chang, C. P., Brocchieri, L., Shen, W. F., Largman, C. and Cleary, M. L. (1996). Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol. Cell. Biol. 16, 1734-1745.
10. Collarini, E. J., Pringle, N., Mudhar, H., Stevens, G., Kuhn, R., Monuki, E. S., Lemke, G. and Richardson, W. D. (1991). Growth factors and transcription factors in oligodendrocyte development. J. Cell Sci. 15, 117-123.
11. Cui, H. and Bulleit, R. F. (1997). Expression of the POU transcription factor Brn-5 inhibits proliferation of NG108-15 cells. Biochem. Biophys. Res. Commun. 236,. 693-696.
12. Dahlstrand, J., Lardelli, M. and Lendahl, U. (1995). Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, hut not all, regions of developing central nervous system. Dev. Brain Res. 84, 109-129.
13. Dignam, J. D., Lebovitz, R. M. and Roeder, R. G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucl. Acids Res. 11, 1475-1489.
14. Fedtsova, N. G. and Turner, E. E. (1995). Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors. Mech. Dev. 53, 291-304.
15. Feng, L., Hatten, M. E. and Heintz, N. (1994). Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron 12, 895-908.
16. Feng, L. and Heintz, N. (1995). Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development 121, 1719-1730.
17. Fishell, G. (1995). Striatal precursors adopt cortical identities in response to local cues. Development 121, 803-812.
18. Frantz, G. D., Bohner, A. P., Akers, R. M. and McConnell, S. K. (1994). Regulation of the POU domain gene SCIP during cerebral cortical development. J. Neurosci. 14, 472-485.
19. Frederiksen, K. and McKay, R. (1988). Proliferation and differentiation of rat neuroepithelial precursor cells in vivo. J. Neurosci. 8, 1144-1151.
20. Fujii, H. and Hamada, H. (1993). A CNS-specific POU transcription factor, Brn-2, is required for establishing mammalian neural cell lineages. Neuron 11, 1197-1206.
21. Gensburger, C., Labourdette, G. and Sensenbrenner, M. (1987). Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro. FEBS Lett. 217, 1-5.
22. Ghosh, A. and Greenberg, M. E. (1995). Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis. Neuron 15, 89-103.
23. Goulding, M. D., Lumsden, A. and Gruss, P. (1993). Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord. Development 117, 1001-1016.
24. Gritti, A., Parati, E. A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D. J., Roisen, F., Nickel, D. D., et al. (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci. 16, 1091-1100.
25. Habener, J. F. (1990). Cyclic AMP response element binding proteins: a cornucopia of transcription factors. Mol. Endocrinol. 4, 1087-1094.
26. He, X., Treacy, M. N., Simmons, D. M., Ingraham, H. A., Swanson, L. W. and Rosenfeld, M. G. (1989). Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature 340, 35-42.
27. Higuchi, R. (1990). Recombinant PCR. In PCR Protocols: a Guide to Methods and Applications (ed. M. A. Innis, D. H. Gelfand, J. J. Sninsky, and T. J. White), pp. 177-183. San Diego: Academic Press.
28. Hockfield, S. and McKay, R. (1985). Identification of major cell classes in the developing mammalian nervous system. J. Neurosci. 5, 3310-3328.
29. Hogan, B., Constantini, F. and Lacey, E. (1986). Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
30. Huo, B., Dozin, B. and Nikodem, V. M. (1997). Identification of a nuclear protein from rat developing brain as heterodimerization partner with thyroid hormone receptor-β. Endocrinology 138, 3283-3289.
31. Imagawa, M., Chiu, R. and Karin, M. (1987). Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell 51, 251-260.
32. Innis, S. M. (1991). Essential fatty acids in growth and development. Prog. Lipid Res. 30, 39-103.
33. Jaegle, M., Mandemakers, W., Broos, L., Zwart, R., Karis, A., Visser, P., Grosveld, F. and Meijer, D. (1996). The POU factor Oct-6 and Schwann cell differentiation. Science 273, 507-510.
34. Johe, K. K., Hazel, T. G., Müller, T., Dugich-Djordjevic, M. M. and McKay, R. D. G. (1996). Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10, 3129-3140.
35. Kurtz, A., Zimmer, A., Schnütgen, E, Brüning, G., Spener, F. and Müller, T. (1994). The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development 120, 2637-2649.
36. Lothian, C. and Lendahl, U. (1997). An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. Eur. J. Neurosci. 9, 452-462.
37. Maniatis, T., Fritsch, E. F. and Sambrook, J. (1989). Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
38. Marks, M. S., Hallenbeck, P. L., Nagata, T., Segars, J. H., Appella, E., Nikodem, V. M. and Ozato, K. (1992). H-2RIIBP (RXRβ) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes. EMBO J. 11, 1419-1435.
39. Marshall, H., Nonchev, S., Sham, M. H., Muchamore, I., Lumsden, A. and Krumlauf, R. (1992). Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity. Nature 360, 737-741.
40. Martinez, M. (1996). Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patients with disorders of peroxisomal biogenesis. Lipids 31, S145-152.
41. Matsuda, M., Katoh-Semba, R., Kitani, H. and Tomooka, Y. (1996). A possible role of the nestin protein in the developing central nervous system in rat embryos. Brain Res. 723, 177-89.
42. Monuki, E. S., Kuhn, R. and Lemke, G. (1993). Repression of the myelin P0 gene by the POU transcription factor SCIP. Mech. Dev. 42, 15-32.
43. Monuki, E. S., Kuhn, R., Weinmaster, G., Trapp, B. and Lemke, G. (1990). Expression and activity of the POU transcription factor SCIP. Science 249, 1300-1303.
44. Nakai, S., Kawano, H., Yudate, T., Nishi, M., Kuno, J., Nagata, A., Jishage, K., Hamada, H., Fujii, H., Kawamura, K., et al. (1995). The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev. 9, 3109-3121.
45. Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M. and Hamada, H. (1990). A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60, 461-472.
46. Okamoto, K., Wakamiya, M., Noji, S., Koyama, E., Taniguchi, S., Takemura, R., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Muramatsu, M., et al. (1993). A novel class of murine POU gene predominantly expressed in central nervous system. J. Biol. Chem. 268, 7449-7457.
47. Papalopulu, N. and Kintner, C. (1993). Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. Development 117, 961-75.
48. Reynolds, B. A. and Weiss, S. (1992). Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-1710.
49. Rhodes, S. J., DiMattia, G. E. and Rosenfeld, M. G. (1994). Transcriptional mechanisms in anterior pituitary cell differentiation. Curr. Opin. Gen. Dev. 4, 709-717.
50. Rosner, M., Vigano, M. A., Ozato, K., Timmons, P. M., Poirier, F., Rigby, P. W. J. and Staudt, L. M. (1990). A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 345, 686-692.
51. Ruiz i Altaba, A. (1994). Pattern formation in the vertebrate neural plate. Trends Neurosci. 17, 233-243.
52. Scholer, H. R., Ruppert, S., Balling, R., Suzuki, N., Chowdhury, K. and Gruss, P. (1990). New type of POU domain in germ line-specific protein Oct-4. Nature 344, 435-439.
53. Schonemann, M. D., Ryan, A. K., McEvilly, R. J., O'Connell, S. M., Arias, C. A., Kalla, K. A., Li, P., Sawchenko, P. E. and Rosenfeld, M. G. (1995). Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev. 9, 3122-3135.
54. Schreiber, E., Tobler, A., Malipiero, U., Schaffner, W. and Fontana, A. (1993). cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. Nucl Acids Res. 21, 253-258.
55. Shihabuddin, L. S., Ray, J. and Gage, F. H. ( 1997). FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord. Exp. Neurol. 148, 577-86.
56. Shimazaki, T., Okazawa, H., Fujii, H., Ikeda, M., Tamai, K., McKay, R. D. G., Muramatsu, M. and Hamada, H. (1993). Hybrid cell extinction and re-expression of Oct-3 function correlates with differentiation potential. EMBO J. 12, 4489-4498.
57. Thompson, C. C. and Bottcher, M. C. (1997). The product of a thyroid hormone-responsive gene interacts with thyroid hormone receptors. Proc. Natl. Acad. Sci. USA 94, 8527-8532.
58. Vicario-Abejón, C., Cunningham, M. G. and McKay, R. D. G. (1995a). Cerebellar precursors transplanted to the neonatal dentate gyrus express features characteristic of hippocampal neurons. J. Neurosci. 15, 6351-6363.
59. Vicario-Abejón, C., Johe, K. K., Hazel, T. G., Collazo, D. and McKay, R. D. G. (1995b). Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron 15, 105-114.
60. Wegner, M., Drolet, D. W. and Rosenfeld, M. G. (1993). POU-domam proteins: Structure and function of developmental regulators. Curr. Opin. Cell Biol. 5, 488-498.
61. Wirth, T., Staudt, L. and Baltimore, D. (1987). An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature 329, 174-178.
62. Witta, S. E., Agarwal, V. R. and Sato, S. M. (1995). X1POU2, a noggin-inducible gene, has direct neuralizing activity. Development 121, 721-730.
63. Xu, L. Z., Sanchez, R., Sali, A. and Heintz, N. (1996). Ligand specificity of brain lipid-binding protein. J. Biol. Chem. 271, 24711-24719.
64. Yeo, S. L., Lloyd, A., Kozak, K., Dinh, A., Dick, T., Yang, X., Sakonju, S. and Chia, W. (1995). On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor. Genes Dev. 9, 1223-36.
65. Yu, R. T., McKeown, M., Evans, R. M. and Umesono, K. (1994) Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx. Nature 370, 375-379.
66. Zimmerman, L., Lendahl, U., Cunningham, M., McKay, R., Parr, B., Gavin, B., Mann, J., Vassileva, G. and McMahon, A. P. (1994). Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron 12, 11-24.