Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: Role of canalicular multispecific organic anion transporter and P-glycoprotein

Cancer Chemotherapy and Pharmacology, Supplement

Volumn 42, Issue , 1998, Pages

  Sugiyama, Yuichi ^a   Kato, Yukio ^a   Chu, Xiao Yan ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Biliary excretion; cMOAT; Irinotecan; P glycoprotein

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; CARRIER PROTEIN; DRUG METABOLITE; GLYCOPROTEIN P; IRINOTECAN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; BILIARY EXCRETION; CONFERENCE PAPER; CONTROLLED STUDY; DIARRHEA; DRUG RESISTANCE; DRUG TRANSPORT; GASTROINTESTINAL TOXICITY; HUMAN; HYPERBILIRUBINEMIA; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031717972     PISSN: 09439404     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800051078     Document Type: Conference Paper

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