-
1
-
-
0023395222
-
Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I
-
Andoh, T., Ishii, K., and Suzuki, Y. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. Proc. Natl. Acad. Sci. USA, 84: 5565-5569, 1987.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 5565-5569
-
-
Andoh, T.1
Ishii, K.2
Suzuki, Y.3
-
2
-
-
0024356003
-
DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues
-
Hsiang, Y-H., Liu, L. F., Wall, M. E., Wani, M. C., Nicholas, A. W., Manikumar, G., Kirschenbaum, S., Silber, R., and Potmesil, M. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. Cancer Res., 49: 4385-4389, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 4385-4389
-
-
Hsiang, Y.-H.1
Liu, L.F.2
Wall, M.E.3
Wani, M.C.4
Nicholas, A.W.5
Manikumar, G.6
Kirschenbaum, S.7
Silber, R.8
Potmesil, M.9
-
3
-
-
0024560495
-
Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: Evidence for a specific receptor site and a relation to antitumor activity
-
Jaxel, C., Kohn, K. W., Wani, M. C., Wall, M. E., and Pommier, Y. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. Cancer Res., 49: 1465-1469, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 1465-1469
-
-
Jaxel, C.1
Kohn, K.W.2
Wani, M.C.3
Wall, M.E.4
Pommier, Y.5
-
4
-
-
0028225471
-
Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials
-
Tanizawa, A., Fujimori, A., Fujimori, Y., and Pommier, Y. Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. J. Natl. Cancer Inst., 86: 836-842, 1994.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 836-842
-
-
Tanizawa, A.1
Fujimori, A.2
Fujimori, Y.3
Pommier, Y.4
-
5
-
-
0025129894
-
An early phase II study of CPT-11: A new derivative of camptothecin, for the treatment of leukemia and lymphoma
-
Ohno, R., Okada, K., Masaoka, T., Kuramoto, A., Arima, T., Yoshida, Y., Ariyoshi, H., Ishimaru, M., Sakai, Y., Oguro, M., Ito, Y., Morishima, Y., Yokomaku, S., and Ota, K. An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma. J. Clin. Oncol., 8: 1907-1912, 1990.
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 1907-1912
-
-
Ohno, R.1
Okada, K.2
Masaoka, T.3
Kuramoto, A.4
Arima, T.5
Yoshida, Y.6
Ariyoshi, H.7
Ishimaru, M.8
Sakai, Y.9
Oguro, M.10
Ito, Y.11
Morishima, Y.12
Yokomaku, S.13
Ota, K.14
-
6
-
-
0005998836
-
Phase I study of the new camptothecin analogue CPT-11 administered every 3 weeks
-
Gandia, D., Armand, J., Chabot, G., Abigerges, D., Rougier, P., Ruffile, P., Cote, C., and Mathieu-Boue, A. Phase I study of the new camptothecin analogue CPT-11 administered every 3 weeks. Proc. Am. Assoc. Cancer Res., 33: 260, 1992.
-
(1992)
Proc. Am. Assoc. Cancer Res.
, vol.33
, pp. 260
-
-
Gandia, D.1
Armand, J.2
Chabot, G.3
Abigerges, D.4
Rougier, P.5
Ruffile, P.6
Cote, C.7
Mathieu-Boue, A.8
-
7
-
-
0028158012
-
Phase I and pharmacological study of novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
-
Rowinsky, E. K., Grochow, L. B., Ettinger, D. S., Sartorius, S. E., Lubejko, B. G., Chen, T-L., Hendricks, C., Rock, M. K., and Donehower, R. C. Phase I and pharmacological study of novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res., 54: 427-436, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 427-436
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Ettinger, D.S.3
Sartorius, S.E.4
Lubejko, B.G.5
Chen, T.-L.6
Hendricks, C.7
Rock, M.K.8
Donehower, R.C.9
-
8
-
-
0028947192
-
Relationship between the pharmacokinetics of irinotecan and diarrhea during combination chemotherapy with cisplatin
-
Kudoh, S., Fukuoka, M., Masuda, N., Yoshikawa, A., Kusunoki, Y., Matsui, K., Negoro, S-I., Takifugi, N., Nakagawa, K., Hirashima, T., Yana, T., and Takada, M. Relationship between the pharmacokinetics of irinotecan and diarrhea during combination chemotherapy with cisplatin. Jpn. J. Cancer Res., 86: 406-413, 1995.
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 406-413
-
-
Kudoh, S.1
Fukuoka, M.2
Masuda, N.3
Yoshikawa, A.4
Kusunoki, Y.5
Matsui, K.6
Negoro, S.-I.7
Takifugi, N.8
Nakagawa, K.9
Hirashima, T.10
Yana, T.11
Takada, M.12
-
9
-
-
0025851286
-
Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer
-
Negoro S., Fukuoka, M., Masuda, N., Takada, M., Kusunoki, Y., Matsui, K., Takifugi, N., Kudoh, S., Niitani, H., and Taguchi, T. Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer. J. Natl. Cancer Inst., 83: 1164-1168, 1991.
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 1164-1168
-
-
Negoro, S.1
Fukuoka, M.2
Masuda, N.3
Takada, M.4
Kusunoki, Y.5
Matsui, K.6
Takifugi, N.7
Kudoh, S.8
Niitani, H.9
Taguchi, T.10
-
10
-
-
0028813952
-
A pharmacokinetic and pharmacodynamic analysis of CPT-11 and its active metabolite SN-38
-
Sasaki, Y., Hakusui, H., Mizuno, S., Morita, M., Miya, T., Eguchi, K., Shinkai, T., Tamura, T., Ohe, Y., and Saijo, N. A pharmacokinetic and pharmacodynamic analysis of CPT-11 and its active metabolite SN-38. Jpn. J. Cancer Res., 86: 101-110, 1995.
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 101-110
-
-
Sasaki, Y.1
Hakusui, H.2
Mizuno, S.3
Morita, M.4
Miya, T.5
Eguchi, K.6
Shinkai, T.7
Tamura, T.8
Ohe, Y.9
Saijo, N.10
-
11
-
-
0027242140
-
Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood, plasma of athymic mice following intraperitoneal administration of CPT-11
-
Araki, E., Ishikawa, M., Iigo, M., Koide, T., Itabashi, M., and Hoshi, A. Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood, plasma of athymic mice following intraperitoneal administration of CPT-11. Jpn. J. Cancer Res., 84: 697-702, 1993.
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 697-702
-
-
Araki, E.1
Ishikawa, M.2
Iigo, M.3
Koide, T.4
Itabashi, M.5
Hoshi, A.6
-
12
-
-
0027461221
-
Inhibition of β-glucuronidase by natural glucuronides of kampo medicines using glucuronide of SN-38 (7-ethyl-10-hydroxycamptothecin) as a substrate
-
Narita, M., Nagai, E., Hagiwara, H., Aburada, M., Yokoi, T., and Kamataki, T. Inhibition of β-glucuronidase by natural glucuronides of kampo medicines using glucuronide of SN-38 (7-ethyl-10-hydroxycamptothecin) as a substrate. Xenobiotica, 23: 5-10, 1993.
-
(1993)
Xenobiotica
, vol.23
, pp. 5-10
-
-
Narita, M.1
Nagai, E.2
Hagiwara, H.3
Aburada, M.4
Yokoi, T.5
Kamataki, T.6
-
13
-
-
0028971415
-
Protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloridc (CPT-11), in rats
-
Takasuna, K., Kasai, Y., Kitano, Y. Mori, K. Kobayashi, R., Hagiwara, T., Kakihata, K., Hirohashi, M., Nomura, M., Nagai, E., and Kamataki, T. Protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloridc (CPT-11), in rats. Jpn. J. Cancer Res., 86: 978-984, 1995.
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 978-984
-
-
Takasuna, K.1
Kasai, Y.2
Kitano, Y.3
Mori, K.4
Kobayashi, R.5
Hagiwara, T.6
Kakihata, K.7
Hirohashi, M.8
Nomura, M.9
Nagai, E.10
Kamataki, T.11
-
14
-
-
0030959378
-
Multispecific organic anion transporter (cMOAT) is responsible for biliary excretion or the camptothecin derivative irinotecan, CPT-11, and its metabolites in rats
-
in press
-
Chu, X-Y., Kato, Y., Niinuma, K., Sudo, K-I., Hakusui, H., and Sugiyama, Y. Multispecific organic anion transporter (cMOAT) is responsible for biliary excretion or the camptothecin derivative irinotecan, CPT-11, and its metabolites in rats. J. Pharmacol. Exp. Ther., in press, 1997.
-
(1997)
J. Pharmacol. Exp. Ther.
-
-
Chu, X.-Y.1
Kato, Y.2
Niinuma, K.3
Sudo, K.-I.4
Hakusui, H.5
Sugiyama, Y.6
-
15
-
-
0025861580
-
ATP-dependent S-(2,4-dinitrophenyl) glutathione transport in canalicular plasma membrane vesicles from rat liver
-
Akerboom, T. P. M., Narayanaswami, V., Kunst, M., and Sies, H. ATP-dependent S-(2,4-dinitrophenyl) glutathione transport in canalicular plasma membrane vesicles from rat liver. J. Biol. Chem., 266: 13147-13152, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 13147-13152
-
-
Akerboom, T.P.M.1
Narayanaswami, V.2
Kunst, M.3
Sies, H.4
-
16
-
-
0025343017
-
Mechanism of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes
-
Kobayashi, K., Sogame, Y., Hara, H., and Hayashi, K. Mechanism of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes. J. Biol. Chem., 265: 7737-7741, 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 7737-7741
-
-
Kobayashi, K.1
Sogame, Y.2
Hara, H.3
Hayashi, K.4
-
17
-
-
0021325788
-
Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles
-
Inoue, M., Akerboom, T. P. M., Sies, H., Kinne, R., Thao, T., and Arias, I. M. Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles. J. Biol. Chem., 259: 4998-5002, 1984.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 4998-5002
-
-
Inoue, M.1
Akerboom, T.P.M.2
Sies, H.3
Kinne, R.4
Thao, T.5
Arias, I.M.6
-
18
-
-
0029880973
-
Expression of a putative ATP-binding cassette region, homologous to that in multidrug resistance-associated protein (MRP), is hereditarily defective in Eisai hyperbilirubinemic rats (EHBR)
-
Ito, K., Suzuki, H., Hirohashi, T., Kume, K., Shimizu., T., and Sugiyama, Y. Expression of a putative ATP-binding cassette region, homologous to that in multidrug resistance-associated protein (MRP), is hereditarily defective in Eisai hyperbilirubinemic rats (EHBR). Int. Hepatol. Commun., 4: 291-298, 1996.
-
(1996)
Int. Hepatol. Commun.
, vol.4
, pp. 291-298
-
-
Ito, K.1
Suzuki, H.2
Hirohashi, T.3
Kume, K.4
Shimizu, T.5
Sugiyama, Y.6
-
19
-
-
0029133131
-
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes
-
Mayer, R., Kartenbeck, J., Büchler, M., Jedlitschky, G., Leier, I., and Keppler, D. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J. Cell Biol., 131: 137-150, 1995.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 137-150
-
-
Mayer, R.1
Kartenbeck, J.2
Büchler, M.3
Jedlitschky, G.4
Leier, I.5
Keppler, D.6
-
20
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Washington DC
-
Paulusma, C. C. Bosma, P. J., Zaman, G. J. R., Bakker, C. T. M., Otter, M., Scheffer, G. E., Scheper, R. J., Borst, P., and Elferink, R. P. J. O. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science (Washington DC), 271: 1126-1128, 1996.
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.R.3
Bakker, C.T.M.4
Otter, M.5
Scheffer, G.E.6
Scheper, R.J.7
Borst, P.8
Elferink, R.P.J.O.9
-
21
-
-
0031031247
-
Molecular cloning of canalicular multispecific organic anion transporter (cMOAT) whose expression is defective in mutant rats with hereditary conjugated hyperbilirubinemia (EHBR)
-
Ito, K., Suzuki, H., Hirohashi, T., Kume, K., Shimizu, T., and Sugiyama, Y. Molecular cloning of canalicular multispecific organic anion transporter (cMOAT) whose expression is defective in mutant rats with hereditary conjugated hyperbilirubinemia (EHBR). Am. J. Physiol., 272: G16-G22, 1997.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Ito, K.1
Suzuki, H.2
Hirohashi, T.3
Kume, K.4
Shimizu, T.5
Sugiyama, Y.6
-
22
-
-
0027382061
-
Kinetic analysis of hepatobiliary transport of organic anions in Eisai hyperbilirubinemic mutant rats
-
Sathirakul, K., Suzuki, H., Yasuda, K., Hanano, M., Tagaya, O., Horie, T., and Sugiyama, Y. Kinetic analysis of hepatobiliary transport of organic anions in Eisai hyperbilirubinemic mutant rats. J. Pharmacol. Exp. Ther., 265: 1301-1312, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.265
, pp. 1301-1312
-
-
Sathirakul, K.1
Suzuki, H.2
Yasuda, K.3
Hanano, M.4
Tagaya, O.5
Horie, T.6
Sugiyama, Y.7
-
23
-
-
0029026940
-
Different biliary excretion systems for glucuronide and sulfate of a model compound: Study using Eisai hyperbilirubinemic rats
-
Takenaka, O., Horie, T., Suzuki, H., and Sugiyama, Y. Different biliary excretion systems for glucuronide and sulfate of a model compound: study using Eisai hyperbilirubinemic rats. J. Pharmacol. Exp. Ther., 274: 1362-1369, 1995.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.274
, pp. 1362-1369
-
-
Takenaka, O.1
Horie, T.2
Suzuki, H.3
Sugiyama, Y.4
-
24
-
-
0029582975
-
Kinetic analysis of hepatobiliary transport for conjugated metabolites in the perfused liver of mutant rats (EHBR) with hereditary conjugated hyperbilirubinemia
-
NY
-
Takenaka, O., Horie, T., Kobayashi K., Suzuki, H., and Sugiyama, Y. Kinetic analysis of hepatobiliary transport for conjugated metabolites in the perfused liver of mutant rats (EHBR) with hereditary conjugated hyperbilirubinemia. Pharm. Res. (NY), 12: 1746-1755, 1995.
-
(1995)
Pharm. Res.
, vol.12
, pp. 1746-1755
-
-
Takenaka, O.1
Horie, T.2
Kobayashi, K.3
Suzuki, H.4
Sugiyama, Y.5
-
25
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins, C. F. ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol., 8: 67-113, 1992.
-
(1992)
Annu. Rev. Cell Biol.
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
26
-
-
0028103708
-
Multiple transport systems for organic anions across the bile canalicular membrane
-
Sathirakul, K., Suzuki, H., Yamada, T., Hanano, M., and Sugiyama, Y. Multiple transport systems for organic anions across the bile canalicular membrane. J. Pharmacol. Exp. Ther., 268: 65-73, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 65-73
-
-
Sathirakul, K.1
Suzuki, H.2
Yamada, T.3
Hanano, M.4
Sugiyama, Y.5
-
27
-
-
0028027840
-
Multiple systems for the biliary excretion of organic anions in rats: Liquiritigenin conjugates as model compounds
-
Shimamura, H., Suzuki, H., Hanano, M., Suzuki, A., Tagaya, O., Horie, T., and Sugiyama, Y. Multiple systems for the biliary excretion of organic anions in rats: Liquiritigenin conjugates as model compounds. J. Pharmacol. Exp. Ther., 271: 370-378, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 370-378
-
-
Shimamura, H.1
Suzuki, H.2
Hanano, M.3
Suzuki, A.4
Tagaya, O.5
Horie, T.6
Sugiyama, Y.7
-
28
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Washington DC
-
Cole, S. P. C., Bhardwaj, J., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C. Stewart, A. J., Kurz, E. U., Duncan, A. M. V., and Deeley, R. G. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (Washington DC), 258: 1650-1654, 1992.
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, J.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.V.9
Deeley, R.G.10
-
29
-
-
0029918142
-
ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP)
-
Loe, D. W., Almquist, K. C. Cole, S. P. C., and Deeley, R. G. ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP). J. Biol. Chem., 271: 9683-9689, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9683-9689
-
-
Loe, D.W.1
Almquist, K.C.2
Cole, S.P.C.3
Deeley, R.G.4
-
30
-
-
0028001416
-
ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein
-
Jedlitschky, G., Leier, I., Buchholz, U., Center, M., and Keppler, D. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res., 54: 4833-4836, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4833-4836
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Center, M.4
Keppler, D.5
-
31
-
-
0027984511
-
4 and structurally related conjugates
-
4 and structurally related conjugates. J. Biol. Chem., 269: 27807-27810, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27807-27810
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
Cole, S.P.C.4
Deeley, R.G.5
Keppler, D.6
-
32
-
-
0028220381
-
ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein
-
Müller, M., Mayer, R., Hero, U., and Keppler, D. ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein. FEBS Lett., 343: 168-172, 1994.
-
(1994)
FEBS Lett.
, vol.343
, pp. 168-172
-
-
Müller, M.1
Mayer, R.2
Hero, U.3
Keppler, D.4
-
33
-
-
0019854279
-
A pharmacokinetic analysis program (MULTI) for microcomputer
-
Yamaoka, K., Tanigawara, Y., Nakagawa, T., and Uno, T. A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-Dyn., 4: 879-885, 1981.
-
(1981)
J. Pharmacobio-Dyn.
, vol.4
, pp. 879-885
-
-
Yamaoka, K.1
Tanigawara, Y.2
Nakagawa, T.3
Uno, T.4
-
34
-
-
0018091195
-
Application of Akaike's Information Criterion (AIC) in the evaluation of linear pharmacokinetic equations
-
Yamaoka, K., Nakagawa, T., and Uno, T. Application of Akaike's Information Criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm., 6: 165-175, 1978.
-
(1978)
J. Pharmacokinet. Biopharm.
, vol.6
, pp. 165-175
-
-
Yamaoka, K.1
Nakagawa, T.2
Uno, T.3
-
35
-
-
0025342506
-
Nonlinear pharmacokinetics of CPT-11 in rats
-
Kaneda, N., and Yokokura, T. Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res., 50: 1721-1725, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 1721-1725
-
-
Kaneda, N.1
Yokokura, T.2
-
36
-
-
0025858296
-
Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion
-
Atsumi, R., Suzuki, W., and Hakusui, H. Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion. Xenobiotica, 21: 1159-1169, 1991.
-
(1991)
Xenobiotica
, vol.21
, pp. 1159-1169
-
-
Atsumi, R.1
Suzuki, W.2
Hakusui, H.3
-
37
-
-
0029876561
-
Pharmacokinetic modulation of irinotecan and metabolites by cyclosporin A
-
Gupta, E., Safa, A. R., Wang, X., and Ratain, M. J. Pharmacokinetic modulation of irinotecan and metabolites by cyclosporin A. Cancer Res., 56: 1309-1314, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 1309-1314
-
-
Gupta, E.1
Safa, A.R.2
Wang, X.3
Ratain, M.J.4
-
38
-
-
0027096415
-
A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues
-
Fassberg, J., and Stella, V. J. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues. J. Pharm. Sci., 81: 676-684, 1992.
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 676-684
-
-
Fassberg, J.1
Stella, V.J.2
-
39
-
-
0001624904
-
Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues: Structure-activity correlations
-
Wani, M. C., Nicholas, A. W., Manikumar, G., and Wall, M. E. Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues: structure-activity correlations. J. Med. Chem., 30: 1774-1779, 1987.
-
(1987)
J. Med. Chem.
, vol.30
, pp. 1774-1779
-
-
Wani, M.C.1
Nicholas, A.W.2
Manikumar, G.3
Wall, M.E.4
-
40
-
-
0027447420
-
The current status of camptothecin analogues as antitumor agents
-
Slichenmyer, W. J., Rowinsky, E. K., Donehower, R. C., and Kaufmann, S. H. The current status of camptothecin analogues as antitumor agents. J. Natl. Cancer Inst., 85: 271-291, 1993.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 271-291
-
-
Slichenmyer, W.J.1
Rowinsky, E.K.2
Donehower, R.C.3
Kaufmann, S.H.4
-
41
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang, Y-H., Hertzberg, R., Hecht, S., and Liu, L. F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem., 260: 14873-14878, 1985.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.-H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
42
-
-
0029912351
-
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump
-
Leier, I., Jedlitschky, G., Buchholz, U., Center, M., Cole, S. P. C. Deeley, R. G., and Keppler, D. ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. Biochem. J., 314: 433-437, 1996.
-
(1996)
Biochem. J.
, vol.314
, pp. 433-437
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
Center, M.4
Cole, S.P.C.5
Deeley, R.G.6
Keppler, D.7
-
44
-
-
0029995238
-
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells
-
Evers, R., Zaman, G. J. R., Deemter, L. V., Jansen, H., Calafat, J., Oomen, L. C. J. M., Elferink, R. P. J. O., Borst, P., and Schinkel, A. H. Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. J. Clin. Invest., 97: 1211-1218, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1211-1218
-
-
Evers, R.1
Zaman, G.J.R.2
Deemter, L.V.3
Jansen, H.4
Calafat, J.5
Oomen, L.C.J.M.6
Elferink, R.P.J.O.7
Borst, P.8
Schinkel, A.H.9
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