Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 416, Issue 1-2, 1998, Pages 1-10

  Chinnasamy, N ^a   Fairbairn, L J ^a   Laher, J ^a   Willington, M A ^a   Rafferty, J A ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

Alkyltransferase; Antitumour agent; Gene therapy; Micronucleus; O6 benzylguanine

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; ETOPOSIDE; FOTEMUSTINE; STREPTOZOCIN; ALKYLATING AGENT; DNA ALKYLTRANSFERASE; DRUG DERIVATIVE; ENZYME INHIBITOR; GUANINE; MUTAGENIC AGENT; NITROSOUREA DERIVATIVE; O(6) BENZYLGUANINE; O(6)-BENZYLGUANINE; ORGANOPHOSPHORUS COMPOUND; TRANSFERASE;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; MALE; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; ANIMAL; BONE MARROW TRANSPLANTATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION;

ALKYL AND ARYL TRANSFERASES; ALKYLATING AGENTS; ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; DNA REPAIR; DRUG SYNERGISM; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION; GUANINE; HUMANS; MALE; MICE; MICRONUCLEUS TESTS; MUTAGENS; MUTATION; NITROSOUREA COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; STREPTOZOCIN;

EID: 0031689610     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00087-4     Document Type: Article

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