The role of in vitro-induced lymphocyte apoptosis in feline immunodeficiency virus infection: Correlation with different markers of disease progression

Journal of Virology

Volumn 72, Issue 11, 1998, Pages 9025-9033

  Holznagel, Edgar ^a,e   Hofmann Lehmann, Regina ^a   Leutenegger, Christian M ^a   Allenspach, Karin ^a   Huettner, Silke ^a   Forster, Ursula ^e   Niederer, Eva ^c   Joller, Helen ^d   Willett, Brian J ^f   Hummel, Urs ^b   Rossi, Giovanni L ^e   Schüpbach, Jörg ^b   Lutz, Hans ^a,c  

^a Dept of Int Veterinary Medicine

^b Swiss Natl Center for Retroviruses

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^e UNIVERSITY OF BERN   (Switzerland)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CAT; CONTROLLED STUDY; CORRELATION FUNCTION; FELINE IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0031686755     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.11.9025-9033.1998     Document Type: Article

References (54)

1. Accornero, P., M. Radrizzani, D. Delia, F. Gerosa, R. Kurrle, and M. P. Colombo. 1997. Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/ CD95L interactions. Blood 89:558-569.
2. Ackley, C. D., J. K. Yamamoto, N. Levy, N. C. Pedersen, and M. D. Cooper. 1990. Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus. J. Virol. 64:5652-5655.
3. Adachi, Y., N. Oyaizu, S. Than, T. W. McCloskey, and S. Pahwa. 1996. IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: correlation with its ability to block culture-induced down-modulation of Bcl-2. J. Immunol. 157:4184-4193.
4. S) gene expression. Eur. J. Immunol. 26:294-299.
5. Akbar, A. N., and M. Salmon. 1997. Cellular environments and apoptosis: tissue microenvironments control activated T-cell death. Immunol. Today 18:72-76.
6. Barlough, J. E., C. D. Ackley, J. W. George, N. Levy, R. Acevedo, P. F. Moore, B. A. Rideout, M. D. Cooper, and N. C. Pedersen. 1991. Acquired immune dysfunction in cats with experimentally induced feline immunodeficiency virus infection: comparison of short-term and long-term infections. J. Acquired Immune Defic. Syndr. 4:219-227.
7. Baumler, C. B., T. Bohler, I. Herr, A. Benner, P. H. Krammer, and K. M. Debatin. 1996. Activation of the CD95 (APO-1/Fas) system in T cells from human immunodeficiency virus type-1-infected children. Blood 88:1741-1746.
8. Beebe, A. M., T. G. Faith, E. E. Sparger, M. Torten, N. C. Pedersen, and S. Dandekar. 1994. Evaluation of in vivo and in vitro interactions of feline immunodeficiency virus and feline leukemia virus. AIDS 8:873-878.
9. Beebe, A. M., T. G. Gluckstern, J. George, N. C. Pedersen, and S. Dandekar. 1992. Detection of feline immunodeficiency virus infection in bone marrow of cats. Vet. Immunol. Immunopathol. 35:37-49.
10. Benito, J. M., J. M. Zabay, J. Gil, M. Bermejo, A. Escudero, E. Sanchez, and E. Fernandez-Cruz. 1997. Quantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infection: changes in the expression of CD45RO, CD45RA, CD11b, CD38, HLA-DR, and CD25 antigens. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 14:128-135.
11. Bishop, S. A., T. J. Gruffydd-Jones, D. A. Harbour, C. R. Stokes. 1993. Programmed cell death (apoptosis) as a mechanism of cell death in peripheral blood mononuclear cells from cats infected with feline immunodeficiency virus (FIV). Clin. Exp. Immunol. 93:65-71.
12. Boni, J., H. Pyra, and J. Schuepbach. 1996. Sensitive detection and quantification of particle-associated reverse transcriptase in plasma of HIV-1 infected individuals by the product-enhanced reverse transcriptase (PERT). J. Med. Virol. 49:23-28.
13. Bonyhadi, M. L., L. Rabin, S. Salimi, D. A. Brown, J. Kosek, J. M. McCune, and H. Kaneshima. 1993. HIV induces thymus depletion in vivo. Nature 363:728-732.
14. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60-66.
15. Clerici, M., A. Sarin, J. A. Berzofsky, A. L. Landay, H. A. Kessler, F. Hashemi, C. W. Hendrix, S. P. Blatt, J. Rusnak, M. J. Dolna, R. L. Coffman, P. A. Henkart, and G. M. Shearer. 1996. Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin. AIDS 10:603-611.
16. Corbeil, J., M. Tremblay, and D. D. Richman. 1996. HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p561ck. J. Exp. Med. 183:39-48.
17. Flynn, J. N., C. A. Cannon, C. E. Lawrence, and O. Jarrett. 1994. Polyclonal B-cell activation in cats infected with feline immunodeficiency virus. Immunology 81:626-630.
18. Gehri, R., S. Hahn, M. Rothen, M. Steuerwald, R. Nuesch, and P. Erb. 1996. The Fas receptor in HIV infection: expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS 10:9-16.
19. Gougeon, M. L., H. Lecoeur, A. Dulioust, M. G. Enouf, M. Crouvoisier, C. Goujard, T. Debord, and L. Montagnier. 1996. Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J. Immunol. 156:3509-3520.
20. Groux, H., G. Torpier, D. Monte, Y. Mouton, A. Capron, and J. C. Ameisen. 1992. Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J. Exp. Med. 175:331-340.
21. Guiot, A. L., D. Rigal, J. Bernaud, C. Aeberle, M. Soulier, and G. Chappuis. 1993. Demonstration of cell death process by apoptosis in cat lymphocytes infected by FIV (feline immunodeficiency virus). C. R. Acad. Sci. Ser. III 316:1297-1304.
22. Hofmann-Lehmann, R., E. Holznagel, A. Aubert, P. Ossent, M. Reinacher, and H. Lutz. 1995. Recombinant FeLV vaccine: long-term protection and effect on course and outcome of FIV infection. Vet. Immunol. Immunopathol. 46:127-137.
23. Hofmann-Lehmann, R., E. Holznagel, P. Ossent, and H. Lutz. 1997. Parameters of disease progression in long-term experimental feline retrovirus (feline immunodeficiency virus and feline leukemia virus) infections: hematology, clinical chemistry and lymphocyte subsets. Clin. Diagn. Lab. Immunol. 4:33-42
24. Holznagel, E., R. Hofmann-Lehmann, K. Allenspach, S. Huettner, B. J. Willett, P. Groscurth, E. Niederer, and H. Lutz. 1996. Flow cytometric detection of activation-induced cell death (apoptosis) in peripheral blood lymphocyte subpopulations from healthy cats. Vet. Immunol. Immunopathol. 52:1-14.
25. Kraus, L. A., W. G. Bradley, R. W. Engelman, K. M. Brown, R. A. Good, and N. K. Day. 1996. Relationship between tumor necrosis factor alpha and feline immunodeficiency virus expressions. J. Virol. 70:566-569.
26. Lawrence, C. E., J. J. Callanan, B. J. Willett, and O. Jarrett 1995. Cytokine production by cats infected with feline immunodeficiency virus: a longitudinal study. Immunology 85:568-574.
27. Lehmann, R., M. Franchini, A. Aubert, C. Wolfensberger, J. Cronier, and H. Lutz. 1991. Vaccination of cats experimentally infected with feline immunodeficiency virus using a recombinant feline leukemia virus vaccine. J. Am. Vet Med. Assoc. 199:1446-1452.
28. Lehmann, R., H. Joller, B. L. Haagmans, and H. Lutz. 1992. Tumor necrosis factor alpha levels in cats experimentally infected with feline immunodeficiency virus: effects of immunization and feline leukemia virus infection. Vet. Immunol. Immunopathol. 35:61-69.
29. Lehmann, R., B. von Beust, E. Niederer, M. A. Condrau, W. Fierz, A. Aubert, C. D. Ackley, M. D. Cooper, M. B. Tompkins, and H. Lutz. 1992. Immunization-induced decrease of the CD4+:CD8+ ratio in cats experimentally infected with feline immunodeficiency virus. Vet. Immunol. Immunopathol. 35:199-214.
30. Lutz, H., R. Hofmann-Lehmann, C. Leutenegger, K. Allenspach, A. M. Cuisinier, J. Cronier, V. Duquesne, and A. Aubert. 1996. Vaccination of cats with recombinant envelope glycoprotein of feline immunodeficiency virus: decreased viral load after challenge infection. AIDS Res. Hum. Retroviruses 12:431-433.
31. Margolick, J. B., A. Munoz, A. D. Donnenberg, L. P. Park, N. Galai, J. V. Giorgi, M. R. G. O'Gorman, J. Ferbas, and the Multicenter Cohort Study. 1995. Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. Nat. Med. 1:674-680.
32. Meyaard, L., S. A. Otto, R. R. Jonker, M. J. Mijnster, R. P. Keet, and F. Miedema. 1992. Programmed death of T cells in HIV-1 infection. Science 257:217-219.
33. Momoi, Y., T. Mizuno, Y. Nishimura, Y. Endo, K. Ohno, T. Watari, R. Goitsuka, H. Tsujimoto, and A. Hasegawa. 1996. Detection of apoptosis induced in peripheral blood lymphocytes from cats infected with feline immunodeficiency virus. Arch. Virol. 141:1651-1659.
34. Nagata, S. 1997. Apoptosis by death factor. Cell 88:355-365.
35. Newell, M. K., J. Vander Wall, K. S. Beard, and J. H. Freed. 1993. Ligation of major histocompatibility complex class II molecules mediates apoptotic cell death in resting B lymphocytes. Proc. Natl. Acad. Sci. USA 90:10459-10463.
36. Noraz, N., J. Gozlan, J. Corbeil, T. Brunner, and S. A. Spector. 1997. HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand. AIDS 11:1671-1680.
37. Novotney, C., R. V. English, J. Housman, M. G. Davidson, M. P. Nasisse, C. R. Jeng, W. C. Davis, and M. B. Tompkins. 1990. Lymphocyte population changes in cats naturally infected with feline immunodeficiency virus. AIDS 4:1213-1218.
38. Ohno, K., T. Nakano, Y. Matsumoto, T. Wazari, R. Goitsuka, H. Nakayama, H. Tsujimoto, and A. Hasegawa. 1993. Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus. J. Virol. 67:2429-2433.
39. Ohno, K., T. Watari, R. Goitsuka, H. Tsujimoto, and A. Hasegawa. 1992. Altered surface antigen expression on peripheral blood mononuclear cells in cats infected with feline immunodeficiency virus. J. Vet. Med. Sci. 54:517-522.
40. Pandolfi, F., M. Pierdominici, A. Oliva, G. D'Offizi, I. Mezzaroma, B. Mollicone, A. Giovannetti, L. Rainaldi, I. Quinti, and F. Aiuti. 1995. Apoptosis-related mortality in vitro of mononuclear cells from patients with HIV infection correlates with disease severity and progression. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 9:450-458.
41. Rideout, B. A., P. F. Moore, and N. C. Pedersen. 1992. Persistent upregulation of MHC class II antigen expression on T-lymphocytes from cats experimentally infected with feline immunodeficiency virus. Vet. Immunol. Immunopathol. 35:71-81.
42. Rojko, J. L., J. R. Hartke, C. M. Cheney, A. J. Phipps, and J. C. Neil. 1997. Cytopathic feline leukemia viruses cause apoptosis in hemolymphatic cells, p. 13-43. In Y. Kuchino and W. E. G. Mueller (ed.), Apoptosis - progress in molecular and subcellular biology. Springer-Verlag KG, Berlin, Germany.
43. Rosenberg, E. S., J. M. Billingsley, A. M. Caliendo, S. L. Boswell, P. E. Sax, S. A. Kalams, and B. D. Walker. 1997. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science 278:1447-1450.
44. Rosenberg, Y. J., A. O. Anderson, and R. Pabst. 1998. HIV-induced decline in blood CD4/CD8 ratios: viral killing or altered lymphocyte trafficking? Immunol. Today 19:10-16.
45. Rothen, M., S. Gratzl, H. H. Hirsch, and C. Moroni. 1997. Apoptosis in HIV-infected individuals is an early marker occurring independently of high viremia. AIDS Res. Hum. Retroviruses 13:771-779.
46. Sieg, S., Y. Huang, and J. Kaplan. 1997. Viral regulation of CD95 expression and apoptosis in T lymphocytes. J. Immunol. 159:1192-1199.
47. Silvestris, F., P. Cafforio, M. A. Frassanito, M. Tucci, A. Romito, S. Nagata, and F. Dammacco. 1996. Overexpression of Fas antigen on T cells in advanced HIV-1 infection: differential ligation constantly induces apoptosis. AIDS 10:131-141.
48. Truman, J. P., M. L. Ericson, C. J. Choqueux-Seebold, D. J. Charron, and N. A. Mooney. 1994. Lymphocyte programmed cell death is mediated via HLA class II DR. Int. Immunol. 6:887-896.
49. Willett, B. J., M. J. Hosie, J. J. Callanan, J. C. Neil, and O. Jarrett. 1993. Infection with feline immunodeficiency virus is followed by the rapid expansion of a CD8+ lymphocyte subset. Immunology 78:1-6.
50. Willett, B. J., L. Picard, M. J. Hosie, J. D. Turner, K. Adema, and P. R. Clapham. 1997. Shared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses. J. Virol. 71:6407-6415.
51. Wolthers, K. C., H. Schuitemaker, and F. Miedema. 1998. Rapid CD4+ T-cell turnover in HIV-1 infection: a paradigm revisited. Immunol. Today 19:44-48.
52. Woo, J. C., G. A. Dean, N. C. Pedersen, and P. F. Moore. 1997. Immunopathologic changes in the thymus during the acute stage of experimentally induced feline immunodeficiency virus infection in juvenile cats. J. Virol. 71:8632-8641.
53. Yoshino, T., L. Cao, R. Nishiuchi, Y. Matsuo, I. Yamadori, E. Kondo, N. Teramoto, K. Hayashi, K. Takahashi, N. Kamikawaji, and T. Akagi. 1995. Ligation of HLA class II molecules promotes sensitivity to CD95 (Fas antigen, APO-1)-mediated apoptosis. Eur. J. Immunol. 25:2190-2194.
54. Zamai, L., E. Falcieri, G. Zauli, A. Cataldi, and M. Vitale. 1993. Optimal detection of apoptosis by flow cytometry depends on cell morphology. Cytometry 14:891-897.