Chemical methods for the characterization of proteolysis in cheese during ripening

Lait

Volumn 77, Issue 1, 1997, Pages 41-76

  McSweeney, P L H ^a   Fox, P F ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Cheese ripening; Methodology; Proteolysis

Indexed keywords

EID: 0031494581     PISSN: 00237302     EISSN: None     Source Type: Journal    
DOI: 10.1051/lait:199713     Document Type: Review

References (231)

1. Abdel Baky AA, Abo Ella WM, Aly ME, Fox PF (1987) Improving the quality of Ras-type cheese made from recombined milk containing high levels of total solids. Food Chem 26, 175-188
2. Addeo F, Chianese L, Di Luccia A, Petrilli P, Mauriello R, Anelli G (1983) Identification of bovine casein variants by gel isoelectric focusing. Milchwissenschaft 38, 586-588
3. Addeo F, Moio L, Chianese L, Stingo C, Di Luccia A (1990a) Improved procedure for detecting bovine and ovine milk mixtures in cheese by isoelectric focusing of para-κ-casein. Milchwissenschaft 45, 221-224
4. 2-caseins. Milchwissenschaft 45, 708-711
5. Addeo F, Chianese L, Salzano A, Sacchi R, Cappuccio U, Ferranti P, Malorni A (1992) Characterization of the 12% trichloroacetic acid-soluble oligopeptides of Parmigiano-Reggiano cheese. J Dairy Res 59, 401-411
6. Addeo F, Chianese L, Sacchi R, Spagna Musso S, Ferranti P, Malorni A (1994) Characterization of the oligopeptides of Parmigiano-Reggiano cheese soluble in 120 g trichloroacetic acid/L. J Dairy Res 61, 365-374
7. Addeo F, Garro F, Intorcia N, Pellegrino L, Resmini P, Chianese L (1995) Gel electrophoresis for the detection of casein proteolysis in cheese. J Dairy Res 62, 297-309
8. Adler-Nissen J, (1979) Determination of the degree of hydrolysis of food protein hydrolyzates by trinitrobenzene-sulphonic acid. J Agric Food Chem 27, 1256-1262
9. Alonso L, Juárez M, Ramos M, Martín-Alvarez PJ (1987) Effects of changes during ripening and frozen storage on the physicochemical and sensory characteristics of Cabrales cheeses. Int J Food Sci Technol 22, 525-534
10. Amantea GF, Skura BJ, Nakai S (1986) Culture effect on ripening characteristics and rheological behaviour of Cheddar cheese. J Food Sci 51, 912-918
11. Amigo L, Ramos M, Calhau L, Barbosa M (1992) Comparison of electrophoresis, isoelectric focusing, and immunodiffusion in determination of cow's and goat's milk in Serra da Estrela cheeses. Lait 72, 95-101
12. Andrews AT (1983) Proteinases in normal bovine milk and their action on caseins. J Dairy Res 50, 45-55
13. Anonymous (1989) Ammonia, UV Method for the Determination of Ammonia in Foodstuffs and Other Materials and for the Determination of Nitrogen After Kjeldahl Digestion. Boehringer-Mannheim, Mannheim, Germany
14. Ardö Y, Gripon JC (1995) Comparative study of peptidolysis in some semi-hard round-eyed cheese varieties with different fat contents. J Dairy Res 62, 543-547
15. Ardö Y, Gripon JC (1991) Chromatographic methods used to measure proteolysis in cheese. Bull Int Dairy Fed 261, 29-34
16. Ardö Y, Meisel H (1991) Methods for direct measurement of peptide bond cleavage in cheese. Bull Int Dairy Fed 261, 10-13
17. Ashworth US (1966) Determination of protein in dairy products by dye-binding. J Dairy Sci 49, 133-137
18. Aston JW, Creamer LK (1986) Contribution of the components of the water-soluble fraction to the flavour of Cheddar cheese. NZ J Dairy Sci Technol 21, 229-248
19. Barlow IE, Lloyd GT, Ramshaw EH (1986) The measurement of proteolysis in Cheddar cheese: a comparison of trinitrobenzene sulphonic acid procedures. Aust J Dairy Technol 41, 79-81
20. Barrefors P, Ekstrand B, Fagerstam L, Larson-Raznikiewicz M, Scharr J, Steffner P (1985) Fast protein liquid chromatography (FPLC) of bovine caseins. Milchwissenschaft 40, 257-260
21. Basch JJ, Farrell HM Jr, Walsh RA, Konstance RP, Kumosinski TF (1989) Development of a quantitative model for enzyme-catalyzed, time-dependent changes in protein composition of Cheddar cheese during storage. J Dairy Sci 12, 591-603
22. Beeby R (1980) Use of fluorescamine at pH 6.0 to follow the action of chymosin on κ-casein and to estimate this protein in milk. NZ J Dairy Sci Technol 15, 99-108
23. Bertacco G, Boschella O, Lercker G (1992) Gas chromatographic determination of free amino acids in cheese. Milchwissenschaft 47, 348-350
24. Bhowmik T, Riesterer R, van Boekel MAJS, Marth EH (1990) Characteristics of low-fat Cheddar cheese made with added Micrococcus or Pediococcus species. Milchwissenschaft 45, 230-235
25. Bican P, Spahni A (1993) Proteolysis in Swiss-type cheeses: a high performance liquid chromatographic study. Int Dairy J 3, 73-84
26. Bican P, Blanc B (1982) Milk protein analysis, a high performance chromatography study. Milchwissenschaft 37, 592-593
27. Bican P, Spahni A (1991) Low molecular mass nitrogen components in ripening cheese. Lebensm Wiss Technol 24, 315-322
28. Biede SL, Hammond BG (1979) Swiss cheese. 1. Chemical analysis. J Dairy Sci 62, 227-237
29. Biais BW, Cunningham A, Yamazaki H (1994) A novel immunofluorescence capillary electrophoresis assay foi the determination of chloramphenicol in milk. Food Agric Immunol 6, 409-417
30. Blakesley RW, Boezi JA (1977) A new staining technique for proteins in polyacrylamide gels using Coomassie brilliant blue G250. Anal Biochem 82, 580-582
31. Bockelmann W (1995 The proteolytic system of starter and non-starter bacteria: components and their importance for cheese ripening. Int Dairy J 5, 977-994
32. Bouton Y, Grappin R (1994) Measurement of proteolysis in cheese: relationship between phosphotungstic acid-soluble N fraction by Kjeldahl and 2, 4, 6-trinitrobenzenesulphonic acid-reactive groups in water-soluble N. J Dairy Res 61, 437-440
33. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254
34. Breen ED (1992) Fractionation and identification of water-soluble and water-insoluble cheese nitrogen. MSc thesis, Nat Univ Ireland, Cork
35. Breen ED, Fox PF, McSweeney PLH (1995) Fractionation of water-soluble peptides from Cheddar cheese. Ital J Food Sci 7, 211-220
36. Bütikofer U, Fuchs D, Murni D, Bosset JO (1990) Beitrag zur Bestimmung biogener Amine in Käse. Vergleich einer verbesserten HPLC-mit einer IC-Methode und Anwendung bei verschiedenen Kasesorten. Mitt Geb Lebensmittelunters Hyg 81, 120-133
37. Bütikofer U, Fuchs D, Bosset JO, Gmur W (1991) Automated HPLC-amino acid determination by precolumn derivatization with OPA and FMOC and comparison with classical ion-exchange chromatography. Chromatographia 31, 441-447
38. Bütikofer U, Ruegg M, Ardo Y (1993) Determination of nitrogen fractions in cheese, evaluation of a collaborative study. Lebensm Wiss Technol 26, 271-275
39. Chakravorty SC, Srinivasan RA, Babbur IJ, Dudani AT, Burde SD, Iya KK (1966) Comparative study of proteolysis during ripening of Cheddar cheese by bacterial milk clotting enzymes and rennet extract. Proc 17th Int Dairy Congr, Munich, 187-198
40. Christensen TMIE, Kristiansen KR, Madsen JS (1989) Proteolysis in cheese investigated by high performance liquid chromatography. J Dairy Res 56, 823-828
41. Christensen TMIE, Bech A-M, Werner H (1991) Methods for crude fractionation (extraction and precipitation) of nitrogen components in cheese. Bull Int Dairy Fed 261, 4-9
42. Church FC, Swaisgood HE, Porter DH, Catignani GL (1983) Spectrophotometric assay using o-phthaldialdehyde for determination of proteolysis in milk and isolated milk proteins. J Dairy Sci 66, 1219-1227
43. Cifuentes A, de Frutos M, Diez-Masa JC (1993) Analysis of whey proteins by capillary electrophoresis using buffer-containing polymeric additives. J Dairy Sci 76, 1870-1875
44. Citti JE, Sandine WE, Elliker PR (1963) Some observations on the Hull method for measurement of proteolysis in milk. J Dairy Sci 46, 337
45. Clegg KM, Lee YK, McGilligan JF (1982) Trinitrobenzene sulphonic acid and ninhydrin reagents for the assessment of protein degradation in cheese samples. J Food Technol 17, 517-520
46. Clemens W (1954) Papierchromatographische Untersuchungen an Käse. Milchwissenschaft 9, 195-201
47. Cliffe AJ, Law BA (1991) A time course study of peptide production in accelerated-ripened Cheddar cheese using reverse phase high performance liquid chromatography. Food Biotechnol 5, 1-17
48. Cliffe AJ, Revell D, Law BA (1989) A method for the reverse phase-high performance liquid chromatography of peptides from Cheddar cheese. Food Chem 34, 147-160
49. Cliffe AJ, Marks JD, Mulholland F (1993) Isolation and characterization of non-volatile flavours from cheese, peptide profile of flavour fractions from Cheddar cheese, determined by reverse phase high-performance liquid chromatography. Int Dairy J 3, 379-387
50. Conti A, Napolitano L, Cantisani SM, Davoli R, Dall-Olio S (1988) Bovine beta-lactoglobulin H-isolation by preparative isoelectric-focusing in immobilized pH gradients and preliminary characterization. J Biochem Biophys Methods 16, 205-214
51. Creamer LK (1991) Electrophoresis of cheese. Bull Int Dairy Fed 261, 14-28
52. s1-casein in Cheddar cheese. NZ J Dairy Sci Technol 9, 9-13
53. Creamer LK, Olson NF (1982) Rheological evaluation of maturing Cheddar cheese. J Food Sci 41, 631-636, 646
54. Creamer LK, Lawrence RC, Gilles J (1985) Effect of acidification of cheese milk on the resultant Cheddar cheese. NZ J Dairy Sci Technol 20, 185-203
55. Davis JG (1965) Cheese. J and A Churchill Ltd, London
56. de Jong L (1975) A quantitative electrophoretic method of studying cheese ripening. Neth Milk Dairy J 29, 162-168
57. de Koning PJ, de Wit JN, Driessen FM (1992) Process conditions affecting age-thickening and gelation of sterilized canned evaporated milk, Neth Milk Dairy J 46, 3-18
58. Desmazeaud MJ, Gripon JC, Le Bars D, Bergère JL (1976) Etude du role des micro-organismes et des enzymes au cours de la maturation des fromages. III. Influence des micro-organismes. Lait 56, 379-396
59. Doi E, Shibata D, Matoba T (1981) Modified colorimetric ninhydrin methods for peptidase assay. Anal Biochem 118, 173-184
60. Edwards J, Kosikowski FV (1983) Bitter compounds from Cheddar cheese. J Dairy Sci 66, 727-734
61. El Soda M, Desmazeaud MJ, Aboudonia S, Kamal N (1981) Acceleration of cheese ripening by the addition of whole cells or cell free extracts from Lactobacillus casei to the cheese curd. Milchwissenschaft 36, 140-142
62. Exterkate FA (1995) Lactococcal cell envelope proteinases: differences, calcium-binding effects and role in cheese ripening. Int Dairy J 5, 995-1018
63. Fernandez M, Fox PF (1997) Fractionation of cheese nitrogen using chitosan. Food Chem 58, 319-322
64. Fernandez-Salguero J, Andres Marcos Alcala M, Esteban MA (1989) Proteolysis of Cahrales cheese and other European blue vein cheese varieties. J Dairy Res 56, 141-145
65. Fields R (1971) The measurement of amino groups in proteins and peptides. Biochem J 124, 581-590
66. Folkertsma B, Fox PF (1992) Use of Cd-ninhydrin reagent to assess proteolysis in cheese during ripening. J Dairy Res 59, 217-224
67. Folkertsma B, Fox PF, McSweency PLH (1996) Accelerated ripening of Cheddar cheese at elevated temperatures. Int Dairy J 6, 1117-1134
68. Foster PMD, Green ML (1974) A quantitative gel filtration method for analysis of the proteinaceous fraction of Cheddar cheese. J Dairy Res 41, 259-268
69. Fox PF (1989) Proteolysis in cheese during manufacturing and ripening. J Dairy Sci 72, 1379-1400
70. Fox PF, Singh TK, McSweeney PLH (1995a) Biogenesis of flavour compounds in cheese. In: Chemistry of Structure/Function Relationships in Cheese (Malin EL, Tunick MH, eds) Plenum Publ Corp, New York, 59-98
71. Fox PF, McSweeney PLH, Singh TK (1995b) Methods for assessing proteolysis in cheese during ripening. In: Chemistry of Structure/Function Relationships in Cheese (Malin EL, Tunick MH, eds) Plenum Publ Corp, New York, 161-194
72. Friedman M, Pang J, Smith GA (1984) Ninhydrin-reactive lysine in food proteins. J Food Sci 49, 10-13, 20
73. Furtado MM, Chandan RC (1985) Ripening changes in blue-mold surface ripened cheese from goat's milk. J Food Sci 50, 545-546
74. Girardet J-M, Saulnier F, Driou A, Linden G, Coddeville G, Spik G (1994) High performance electrophoresis chromatography of bovine milk component 3 glycoproteins. J Dairy Sci 77, 1205-1215
75. González de Llano D, Ramos M, Polo C (1987) Gel filtration and high performance liquid chromatographic analysis of phosphotungstic acid soluble peptides from blue cheeses. Chromatographia 23, 764-766
76. González de Llano D, Polo C, Ramos M (1991) Production, isolation and identification of low molecular mass peptides from blue cheese by high performance liquid chromatography. J Dairy Res 58, 363-372
77. González de Llano D, Ramos M, Martín-Alvarez PJ (1993) Comparative study of different methods for evaluating proteolysis in blue cheese. Z Lebensm Unters Forsch 196, 29-31
78. Gordon MJ, Huang X, Petoney SL Jr, Zare RN (1988) Capillary electrophoresis. Science 242, 224-228
79. Gouldsworthy AM, Leaver J, Banks JM (1996) Application of mass spectrometry sequencing technique for identifying peptides present in Cheddar cheese. Int Dairy J 6, 781-790
80. Green ML, Foster PDM (1974) Comparison of the rates of proteolysis during ripening of Cheddar cheeses made with calf rennet and swine pepsin as coagulants. J Dairy Res 41, 269-282
81. Gripon JC (1993) Mould-ripened cheeses. In: Cheese: Chemistry, Physics and Microbiology, vol 2 (ed, PF Fox) Chapman and Hall, London, 111-136. 2nd edn
82. Gripon JC, Desmazeaud MJ, Le Bars D, Bergère JL (1975) Etude du role des micro-organismes et des enzymes au cours de la maturation des fromages. II. Influence de la presure commerciale. Lait 55, 502-516
83. Gripon JC, Desmazeaud MJ, Le Bars D, Bergère JL (1977) Role of proteolytic enzymes of Streptococcus lactis, Penicillium roqueforti and Penicillium caseicolum during cheese ripening. J Dairy Sci 60, 1532-1538
84. Guinee TP, Pudja PD, Reville WJ, Harrington D, Mulholland EO, Cotter M, Cogan TM (1995) Composition, microstructure and maturation of semi-hard cheeses from high protein ultrafiltered milk retentates with different levels of denatured whey proteins. Int Dairy J 5, 543-568
85. Guo MR, Kindstedt PS (1995) Age-related changes in the water-phase of Mozzarella cheese. J Dairy Sci 78, 2099-2107
86. Gupta SK, Whitney RM, Tuckey SL (1974) Brine soluble protein of Cheddar and Gouda cheese. J Dairy Sci 57, 540-544
87. Haasnoot W, Stouter P, Venema DP (1989) High performance liquid chromatography determination of the extent of proteolysis in Gouda cheese. J Chromatogr 483, 319-329
88. Habeeb AFS (1966) Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. Anal Biochem 14, 328-336
89. Harwalkar VR, Elliott JA (1971) Isolation of bitter and astringent fractions from Cheddar cheese. J Dairy Sci 54, 8-11
90. Hickey MW, van Leeuwen H, Hillier AJ, Jago GR (1983) Amino acid accumulation in Cheddar cheese manufactured from normal and ultrafiltered milk. Aust J Dairy Technol 38, 110-113
91. Huber L, Klostermeyer H (1974) Isolierung und Identifizierung eines Bitterstoffes aus Butterkäse. Milchwissenschaft 29, 449-455
92. Hull ME (1947) Studies on milk proteins. II. Colorimetric determination of the partial hydrolysis of the proteins in milk. J Dairy Sci 30, 881-884
93. Inikhov GS (1951) Chemical Analysis of Milk Products. Part II. Food Industry Publ, Moscow
94. IDF (1991) Chemical methods for evaluating proteolysis in cheese maturation. Bull Int Dairy Fed 261
95. Jarrett WD, Aston JW, Dulley JR (1982) A simple method for estimating free amino acids in Cheddar cheese. Aust J Dairy Technol 37, 55-58 (corr 1983, 38)
96. s1-casein by proteinases of Streptococcus cremoris H61. J Food Sci 51, 1253-1256, 1264
97. Katsiari MC, Voutsinas LP (1994) Manufacture of low-fat Kefalograviera cheese. Int Dairy J 4, 533-553
98. Kim HH, Jimenez-Flores R (1994) Comparison of milk proteins using preparative isoelectric focusing followed by polyacrylamide gel electrophoresis. J Dairy Sci 77, 2177-2190
99. Kosikowsky FV (1951a) Paper chromatography of the free amino acids in American Cheddar cheese. J Dairy Sci 34, 228-234
100. Kosikowsky FV (1951b) The liberation of the free amino acids in raw and pasteurized milk Cheddar cheese during ripening. J Dairy Sci 34, 235-241
101. Kroger M, Weaver JC (1979) Use of protein dye-binding values as indicators of the 'chemical age' of conventionally made Cheddar cheese and hydrolyzed-lactose Cheddar cheese. J Food Sci 44, 304-305
102. Kuchroo CN, Fox PF (1982a) Soluble nitrogen in Cheddar cheese: comparison of extraction procedures. Milchwissenschaft 37, 331-335
103. Kuchroo CN, Fox PF (1982b) Fractionation of water-soluble nitrogen from Cheddar cheese: chemical methods. Milchwissenschaft 37, 651-653
104. Kuchroo CN, Fox PF (1983a) Fractionation of the water-soluble nitrogen from Cheddar cheese: chromatographic methods. Milchwissenschaft 38, 76-79
105. Kuchroo CN, Fox PF (1983b) A fractionation scheme for the water-soluble nitrogen in Cheddar cheese. Milchwissenschaft 38, 389-391
106. Kuchroo CN, Rahilly J, Fox PF (1983) Assessment of proteolysis in cheese by reaction with trinitrobenzene sulphonic acid. Irish J Food Sci Technol, 129-133
107. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
108. Lagerwerf FM, van Wassenaar PD, Haverkamp J (1995) Comparison of Cheddar cheeses produced with recombinant chymosin with calf rennet using two dimensional high-performance liquid chromatography. J Dairy Res 62, 673-679
109. Laleye LC, Simard RE, Grosselin C, Lee BH, Giroux RN (1987) Assessment of Cheddar cheese quality by chromatographic analysis of free amino acids and biogenic amines. J Food Sci 52, 303-307, 311
110. Lane CN, Fox PF (1996) Contribution of starter and adjunct lactobacilli to proteolysis in Cheddar cheese during ripening. Int Dairy J 6, 715-728
111. Lau KY, Barbano DM, Rasmussen RR (1991) Influence of pasteurization on protein breakdown in Cheddar cheese during aging. J Dairy Sci 74, 727-740
112. Lawrence RC, Gilles J, Creamer LK (1983) The relationship between cheese texture and flavour. NZ J Dairy Sci Technol 18, 175-190
113. s2-casein. J Dairy Res 56, 817-821
114. Ledford RA, O'Sullivan AC, Nath KR (1966) Residual casein fractions in ripened cheese determined by polyacrylamide-gel electrophoresis. J Dairy Sci 49, 1098-1101
115. Lemieux L, Puchades R, Simard RE (1989) Size-exclusion HPLC separation of bitter and astringent fractions from Cheddar cheese made with added Lactobacillus strains to accelerate ripening. J Food Sci 54, 1234-1237
116. Lemieux L, Puchades R, Simard RE (1990) Free amino acids in Cheddar cheese: comparison of quantitation methods. J Food Sci 55, 1552-1554
117. Lindeberg J (1996a) Capillary electrophoresis in food analysis. Food Chem 55, 73-94
118. Lindeberg J (1996b) Addendum to capillary electrophoresis in food analysis. Food Chem 55, 95-101
119. Lindqvist B (1962) Preparative separation of high molecular weight peptides of cheese. In: Proc 16th lut Dairy Congr, Copenhagen B, 673-678
120. Lindqvist B, Storgards T (1959) Changes in casein during cheese ripening. In: Proc 15th Int Dairy Congr, London 2, 679-684
121. Lindqvist B, Storgards T, Goransson MB (1953) Electrophoresis in paper as a means of studying the ripening process in cheese. Proc 13th Int Dairy Congr, The Hague 3, 1261-1268
122. Lucey JA, Gorry C, Fox PF (1993) Changes in the acid-base buffering curves during the ripening of Emmental cheese. Milchwissenschaft 48, 183-186
123. Mabbitt LA (1955) Quantitative estimation of the amino acids in Cheddar cheese and their importance in flavour. J Dairy Res 22, 224-231
124. Madkor SA, Fox PF, Shalabi SI, Metwally NH (1987) Studies on the ripening of Stilton cheese: proteolysis. Food Chem 25, 13-19
125. Marshall T, Gilliland D, Williams KM (1988) Sodium dodecylsulphate/ polyacrylamide gel electrophoresis of milk proteins: application to cheese. Biochem Soc Trans 16, 165-166
126. Martley FG, Crow VL (1993) Interactions between non-starter microorganisms during cheese manufacture and ripening. Int Dairy J 3, 461-483
127. McGann TCA, Mathiassen A, O'Connell JA (1972) Applications of the pro-milk Mk II. III. Rapid estimation of casein in milk and protein in whey. Lab Pract 21, 628-631, 650
128. McGugan WA, Emmons DB, Larmond E (1979) Influence of volatile and nonvolatile fractions on intensity of Cheddar cheese flavor. J Dairy Sci 62, 398-403
129. McSweeney PLH, Fox PF (1993) Cheese, methods of chemical analysis, In: Cheese, Chemistry, Physics and Microbiology. Vol 1. General Aspects (Fox PF. ed) Chapman and Hall. London, 341-388, 2nd edn
130. McSweeney PLH, Fox PF, Lucey JA, Jordan KN, Cogan TM (1993a) Contribution of the indigenous microflora to the maturation of Cheddar cheese. Int Dairy J 3, 613-634
131. s1-casein. J Dairy Res 60, 401-412
132. McSweeney PLH, Pochet S, Fox PF, Healy A (1994a) Partial identification of peptides from the water-insoluble fraction of Cheddar cheese. J Dairy Res 61, 587-590
133. McSweeney PLH, Walsh E, Fox PF, Cogan TM, Drinan FD, Castelo-Gonzalez M (1994b) A procedure for the manufacture of Cheddar cheese under controlled bacteriological conditions and the effect of adjunct lactobacilli on cheese quality. Irish J Agric Food Res 33, 183-192
134. McSweeney PLH, Lynch CM, Walsh EM, Fox PF, Jordan, KN, Cogan TM, Drinan FD (1995) Role of non-starter lactic acid bacteria in Cheddar cheese ripening. In: Proc 4th Cheese Symp, Moorepark, Fermoy, Co Cork, 32-45
135. Melachouris NP, Tuckey SL (1966) Changes in the proteins in Cheddar cheese made from milk heated at different temperatures. J Dairy Sci 49, 800-805
136. Michalke B (1995) Capillary electrophoresis method for a clear identification of Seleno amino acids in complex matrices like human milk. Fresenius J Anal Chem 351, 6711-676
137. Moio L, Di Luccia A, Addeo F (1989) Fast isoelectric-focusing of milk-proieins on small ultrathin polyacrylamide gels containing urea. Electrophoresis 10, 533-535
138. Moio L, Chianese L, Rivemale M, Addeo F (1992) Fast detection of bovine milk in Roquefort cheese with PhastSystem® by gel isoelectric focusing and immunoblotting. Lait 72, 87-93
139. Mojarro-Guerra SH, Amado R, Arrigoni E, Solms J (1991) Isolation of ow-molecular weight taste peptides from Vacherin Mont d'Or cheese. J Food Sci 56, 943-947
140. Moore S, Stein WH (1948) Photometric ninhydrin method for use in the chromatography of amino acids. J Biol Chem 176, 367-388
141. Moore S, Stein WH (1954) A modified ninhydrin reagent for the photometric determination of amino acids and related compounds. J Biol Chem 211, 907-913
142. Morawski J, Alden P, Sims A (1993) Analysis of cationic nutrients from foods by ion chromatography. J Chromatogr 640, 359-364
143. Morr CV (1971) Comparison of protein preparation procedures and starch versus polyacrylamide gel electrophoresis for examining casein degradation products in cheese. J Dairy Sci 54, 339-343
144. Morris HA, Holt C, Brooker BE, Banks JM, Manson W (1988) Inorganic constituents of cheese, analysis of juice from a one-month old Cheddar cheese and the use of light and electron microscopy to characterize the crystalline phases. J Dairy Res 55, 255-268
145. s1-casein. J Dairy Res 46, 641-651
146. Nath KR, Ledford RA (1973) Growth response of Lactobacillus casei variety casei to the proteolysis products in cheese during ripening. J Dairy Sci 56, 710-715
147. Ney KH (1985) N-Endständige Aminosäuren der Peptide aus reifem Cheddarkäse. Milchwissenschaft 40, 207-208
148. Noomen A (1977a) Noordhollandse Meshanger cheese, a novel method for research on cheese ripening. 2, The ripening of the cheese. Neth Milk Dairy J 31, 75-102
149. Noomen A (1977b) A rapid method for the estimation of the dissolved and the undissolved nitrogen compounds in cheese. Neth Milk Dairy J 31, 163-176
150. O'Keeffe AM, Fox PF, Daly C (1978) Proteolysis in Cheddar cheese: role of coagulant and starter bacteria. J Dairy Res 45, 465-477
151. O'Keeffe RB, Fox PF, Daly C (1976) Contribution of rennet and starter proteases to proteolysis in Cheddar cheese. J Dairy Res 43, 97-107
152. O'Sullivan M, Fox PF (1990) A scheme for partial fractionation of cheese peptides. J Dairy Res 57, 135-139
153. Ollikainen P (1990) Titration - a rapid method for the determination of proteolysis in cheese. J Dairy Res 57, 149-150
154. Omar MM (1984) Microstructure, free amino acids and free fatty acids in Ras cheese. Food Chem 15, 19-29
155. Ordonez JA, Burgos J (1977) Etude de la variété de fromage «Ulloa». I. Evolution de la flore microbienne et des composants azotés au cours de la maturation. Lait 57, 150-163
156. Otte J, Kristiansen KR, Zakora M, Qvist KB (1994) Separation of individual whey proteins and measurement of α-lactalbumin and β-lactoglobulin by capillary zone electrophoresis. Neth Milk Dairy J 48, 81-97
157. Pant I, Trenerry VC (1995) The determination of sorbic acid and benzoic acid in a variety of beverages and foods by micellar electrokinetic chromatography. Food Chem 53, 219-226
158. Pearce KN (1979) Use of fluorescamine to determine the rate of release of the caseino-macropeptide in rennet treated milk. NZ J Dairy Sci Technol 14, 233-239
159. Pearce KN, Karahalios D, Friedman M (1988) Ninhydrin assay for proteolysis in ripening cheese. J Food Sci 53, 432-435, 438
160. Peterson RF, Nauman LW, McMeekin TL (1957) The separation of amino acid composition of a pure phosphopeptone prepared from β-casein by the action of trypsin. J Am Chem Soc 80, 95-99
161. Peterson SD, Marshall RT (1990) Nonstarter lactobacilli in Cheddar cheese: a review. J Dairy Sci 73, 1395-1410
162. Petrilli P (1982) A simple BASIC program for peptide localization by its amino acid composition. Ital J Biochem 31, 391-395
163. Pham AM, Nakai S (1984) Application of stepwise discriminant analysis to high-pressure liquid chromatography profiles of water extract for judging ripening of Cheddar cheese. J Dairy Sci 67, 1390-1396
164. Picon A, Gaya P, Medina M, Nuñez M (1994) The effect of liposome encapsulation of chymosin derived by fermentation on Manchego cheese ripening. J Dairy Sci 77, 16-23
165. Polo C, Ramos M, Sanches R (1985) Free amino acids by high performance liquid chromatography and peptides by gel electrophoresis in Mahon cheese during ripening. Food Chem 16, 85-96
166. Polychroniadou A (1988) A simple procedure using trinitrobenzene sulphonic acid for monitoring proteolysis in cheese. J Dairy Res 55, 585-596
167. Polychroniadou A, Vlachos J (1979) Les acides aminés du fromage Télémé. Lait 59, 234-243
168. Poznanski S, Habaj B, Rymaszewski J, Rapazynski T (1966) Influence of different starter cultures on the protein breakdown in Edam cheese. In: Proc 17th Int Dairy Congr, Munich, 555-564
169. Pretswell EL, McGaw BA, Morrison AR (1995) The comparison of capillary zone electrophoresis and atomic spectroscopy for the determination of the cation content of a standard reference material IAEA-A-11 milk powder. Talanta 42, 283-289
170. Puchades R, Lemieux L, Simard RE (1989a) Evolution of free amino acids during the ripening of Cheddar cheese containing added lactobacilli strains. J Food Sci 54, 885-888, 946
171. Puchades R, Lemieux L, Simard RE (1989b) Sensitive, rapid and precise determination of L-glutamic acid in cheese using a flow injection system with immobilized enzyme column. J Food Sci 54, 423-426
172. Puchades R, Lemieux L, Simard RE (1990) Determination of free amino acids in cheese by flow injection analysis with an enzyme reactor and chemiluminescence detector. J Food Sci 55, 1555-1558, 1578
173. Ramos M, Caceres I, Polo C, Alonso L, Juarez M (1987) Effect of freezing on soluble nitrogen fraction of Cabrales cheese. Food Chem 24, 271-278
174. Rank TC, Grappin R, Olson NF (1985) Secondary proteolysis of cheese during ripening. A review. J Dairy Sci 68, 801-805
175. Reiter B, Sorokin Y, Pickering A, Hall AJ (1969) Hydrolysis of fat and protein in small cheeses made under aseptic conditions. J Dairy Res 36, 65-76
176. Reps A (1993) Bacterial surface-ripened cheeses. In: Cheese, Chemistry, Physics and Microbiology, vol 2 (Fox PF, ed) Chapman and Hall, London, 137-172, 2nd edn
177. Reville WJ, Fox PF (1978) Soluble protein in Cheddar cheese. A comparison of analytical methods. Irish J Food Sci Technol 2, 67-76
178. Roudot-Algaron F, Le Bars D, Einhorn J, Adda J, Gripon JC (1993) Flavor constituents of aqueous fraction extracted from Comté cheese by liquid carbon dioxide. J Food Sci 58, 1005-1009
179. Roudot-Algaron F, Kerhoas L, Le Bars D, Einhorn J, Gripon JC (1994) Isolation of γ-glutamyl peptides from Comté cheese. J Dairy Sci 77, 1161-1166
180. Salji JP, Kroger M (1981) Proteolysis and lipolysis in ripening Cheddar cheese made with conventional bulk starter and with frozen concentrated direct-to-the-vat culture. J Food Sci 46, 1345-1348
181. Salvat-Brunaud D, Maubois JL, Le Graet Y, Piot M, Maillard MB, Corre C, Thierry A (1995) Extraction et analyse de la phase aqueuse de l'Emmental à quatre stades d'affinage. Lait 75, 239-249.
182. Samples DR, Richter RL, Dill CW (1984) Measuring proteolysis in Cheddar cheese slurries, comparison of Hull and trinitrobenzene sulfonic acid procedures. J Dairy Sci 67, 60-63
183. Santoro M, Leone AM, La Notte E, Liuzzi VA (1987) Fractionation of soluble nitrogen in Provolone cheese. I. Milchwissenschaft 42, 709-712
184. Schmitt M, Saulnier F, Malhautier L, Linden G (1993) Effect of temperature on the salt balance of milk studied by capillary electrophoresis. J Chromatogr 640, 419-424
185. Sciancalepore V, Alviti FS (1987) A dialysis method for measuring cheese ripening. Milchwissenschaft 42, 220-221
186. Sciancalepore V, Longone V (1988) Rapid methods for measuring the degree of proteolysis as cheese ripening index. Milchwissenschaft 43, 357-359
187. Shalabi SI, Fox PF (1967) Electrophoretic analysis of cheese: comparison of methods. Irish J Food Sci Technol 11, 135-151
188. Shindo K, Sakurada K, Niki R, Arima S (1980) Studies on immobilized chymosin. 5. Experiments in cheese-making with immobilized chymosin. Milchwissenschaft 35, 527-530
189. Singh A, Ganguli NC (1972) Changes in peptides and amino acids in cheese during ripening. Milchwissenschaft 27, 412-416
190. Singh TK, Fox PF, Højrup P, Healy A (1994) A scheme for the fractionation of cheese nitrogen and identification of principal peptides. Int Dairy J 4, 111-122
191. Singh TK, Fox PF, Healy A (1995) Water soluble peptides in Cheddar cheese: isolation and identification of peptides in the UF retentate of water-soluble fractions. J Dairy Res 62, 629-640
192. Singh TK, Fox PF, Healy A (1997) Isolation and identification of further peptides in the diafiltration retentate of the water-soluble fraction of Cheddar cheese. J Dairy Res 64 (in press)
193. Smith AM, Nakai S (1990) Classification of cheese varieties by multivariate analysis of HPLC profiles. Can Inst Food Sci Technol J 23, 53-58
194. St. Martin M. Paquin P (1990) Ion exchange fast protein liquid chromatography, optimization of the purification of caseins using a non-denaturing detergent. J Dairy Res 57, 63-68
195. Storgards T, Lindqvist B (1953) Untersuchungen über die Käsereifung. I. Chromatographische Untersuchungen über das Vorkommen von Aminosäuren in verschiedenen Kasesorten, Milchwissenschaft 8, 5-10
196. Strange ED, Malin EL Van Hekken DL, Basch JJ (1992) Chromatographic and electrophoretic methods used for analysis of milk proteins. J Chromatogr 624, 81-102
197. Tegtmeyer P, Schwartz M, Collins JK, Rundell K (1975) Regulation of tumor antigen synthesis by simian virus 40 gene A. J Virol 16, 168-178
198. Tieleman AE, Warthesen JJ (1991) Comparison of three extraction procedures to characterize Cheddar cheese proteolysis. J Dairy Sci 74, 3686-3694
199. Tienstra PA, van Reil JAM, Mingorance MD, Olieman C (1992) Assessment of the capabilities of capillary zone electrophoresis for the determination of hippuric and orotic acid in whey. J Chromatogr 608, 357-361
200. Tokita F, Nakanishi T (1962) On the distributive patterns of lower
201. Tokita F, Hosono A (1968) An investigation about Limburger cheese ripening by gel filtration on Sephadex. Milchwissenschaft 23, 758-761
202. Trieu-Cuot P, Gripon JC (1982) A study of proteolysis during Camembert cheese ripening using isoelectric focusing and two-dimensional electrophoresis. J Dairy Res 49, 501-510
203. Tsarichenko AP (1966) New ninhydrin reagent for quantitative determination of amino acids in eluates in column chromatography. Nauchn Tr Krasnodar Gos Pedogog Inst 70, 86-88; cited from Chem Abstr (1967) 67, 79479c
204. Tsarichenko AP (1966) New ninhydrin reagent for quantitative determination of amino acids in eluates in column chromatography. Nauchn Tr Krasnodar Gos Pedogog Inst 70, 86-88; cited from Chem Abstr (1967) 67, 79479c
205. Tunick MH, Mackey KL, Shieh JJ, Smith PW, Cooke P, Malin EL (1993) Rheology and microstructure of low-fat Mozzarella cheese. Int Dairy J 3, 649-662
206. Udenfried S, Stein S, Bohlen P, Darman W Leimgruber W, Weigele M (1972) Fluorescamine, a reagent for assay of amino acids, peptides, proteins and primary amines in the picomole range. Science 178, 871-872
207. Urbach G (1993) Relations between cheese flavour and chemical composition. Int Dairy J 3, 389-422
208. Vakaleris DG, Price WV (1959) A rapid spectrophotometric method for measuring cheese ripening. J Dairy Sci 42, 264-276
209. Vakaleris DG, Olson NF, Price WV, Knight SG (1960) A study of the ripening of Dariworld and Cheddar cheese with special emphasis on proteolysis. J Dairy Sci 43, 1058-1067
210. van den Berg G, de Koning PJ (1990) Gouda cheese-making with purified calf chymosin and microbiologically produced chymosin. Neth Milk Dairy J 44, 189-205
211. van Hekken DL, Thompson MP (1992) Application of Phast™ system to the resolution of bovine milk proteins on urea-polyacrylamide gel electrophoresis. J Dairy Sci 75, 1204-1210
212. van Hooydonk ACM, Olieman C (1982) A rapid sensitive high-performance liquid chromatographic method of following the action of chymosin in milk. Neth Milk Dairy J 36, 153-158
213. Venema DP, Herstel H, Elenbaas HL (1987) Determination of ripening time of Edam and Gouda cheese by chemical analysis. Neth Milk Dairy J 41, 215-226
214. Vijayalakshmi MA, Lemieux L, Amiot J (1986) High performance size exclusion liquid chromatography of small molecular weight peptides from protein hydrolysates using methanol as mobile phase additive. J Liq Chromatogr 9, 3559-3576
215. Visser FMW (1977) Contribution of enzymes from rennet, starter bacteria and milk to proteolysis and flavour development in Gouda cheese. 3. Protein breakdown, analysis of the soluble nitrogen and amino acid fractions. Neth Milk Dairy J 31, 210-239
216. Visser S, Slangen KJ, Hup G (1975) Some bitter peptides from rennet-treated casein. A method for their purification, utilizing chromatographic separation on silica gel. Neth Milk Dairy J 29, 319-334
217. Visser S, Hup G, Exterkate FA, Stadhouders J (1983a) Bitter peptides in cheese. 2. Model studies on the formation and degradation of bitter peptides by proteoly tic enzymes from calf rennet, starter cells and starter cell fractions. Neth Milk Dairy J 37, 169-180
218. Visser S, Slangen KJ, Hup G, Stadhouders J (1983b) Bitter flavour in cheese. 3. Comparative gel-chromatographic analysis of hydrophobic peptide fractions from twelve Gouda-type cheeses and identification of bitter peptides isolated from a cheese made with Streptococcus cremoris strain HP. Neth Milk Dairy J 37, 181-192
219. s2-casein from bovine casein. Neth Milk Dairy J 44, 43-48
220. Vreeman WJ, Visser S, Slangen CJ, van Riel JAM (1986) Characterization of bovine κ-casein fractions and the kinetics of chymosin-induced macropeptide release from carbohydrate-free and carbohydrate-containing fractions determined by high performance gel permeation chromatography. Biochem J 240, 87-97
221. Wallace JM, Fox PF (1994) Comparison of different methods for quantitation of peptides/amino acids in the water-soluble fraction of Cheddar cheese. In: Proc FLAIR Meeting, Lisbon, 15-18 April 1994, 41-58
222. Weaver JC, Kroger M, Thompson MP (1978) Free amino acid and rheological measurement on hydrolysed lactose Cheddar cheese during ripening. J Food Sci 43, 579-583
223. Weigele M, de Bernardo SL, Tengi JP, Leimgruber W (1972) A novel reagent for the fluorometric assay of primary amines. J Am Chem Soc 94, 5927-5928
224. Wilkinson MG, Guinee TP, O'Callaghan DM, Fox PF (1992) Effect of commercial enzymes on proteolysis and ripening in Cheddar cheese. Lait 72, 449-459
225. Wilkinson MG, Guinee TP, O'Callaghan DM, Fox PF (1994) Autolysis and proteolysis in different strains of starter bacteria during Cheddar cheese ripening. J Dairy Res 61, 249-262
226. Wood AF, Aston JW, Douglas GK (1985) The determination of free amino acids in cheese by capillary column gas-liquid chromatography. Aust J Dairy Technol 40, 166-169
227. Young PM, Astephen NE, Wheat TE (1992) Effects of pH and buffer composition on peptide separations by high-performance liquid chromatography and capillary electrophoresis. LC-GC 10, 26-30
228. Yun JJ, Barbano DM, Kindsledt PS, Larose KL (1995) Mozzarella cheese: impact of whey pH at draining on chemical composition, proteolysis, and functional properties. J Dairy Sci 78, 1-7
229. Yvon M, Chabanet C, Pélissier JP (1989) Solubility of peptides in trichloroacetic acid (TCA) solutions. Int J Peptide Protein Res 34, 166-176
230. Zarmpoutis IV, McSweeney PLH, Beechinor J, Fox PF (1996) Proteolysis in the Irish farmhouse blue cheese, Chetwynd. Irish J Agric Food Res 35, 25-36
231. Zeece M (1992) Capillary electrophoresis: a new analytical tool for food science. Trends Food Sci Technol 3, 6-10