메뉴 건너뛰기




Volumn 11, Issue 6, 1997, Pages 1079-1114

Stem cells in chronic myelogenous leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BUSULFAN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD71 ANTIGEN; COLLAGEN TYPE 4; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; COMPLEMENTARY DNA; CYTOKINE; CYTOKINE RECEPTOR; F ACTIN; FIBRONECTIN; FOCAL ADHESION KINASE; GROWTH FACTOR; GUANINE; HLA DR ANTIGEN; HYBRID PROTEIN; INTEGRIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; ONCOPROTEIN; PAXILLIN; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; SERASPENIDE; THROMBOSPONDIN; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; TYROSINE; UNINDEXED DRUG;

EID: 0031474526     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8588(05)70484-6     Document Type: Article
Times cited : (7)

References (315)
  • 1
    • 0028672741 scopus 로고
    • Genetic approaches to defining signaling by the CML-associated tyrosine kinase BCR-ABL
    • D.E. Afar A. Goga L. Cohen Genetic approaches to defining signaling by the CML-associated tyrosine kinase BCR-ABL Cold Spring Harb Symp Quant Biol 59 1994 589
    • (1994) Cold Spring Harb Symp Quant Biol , vol.59 , pp. 589
    • Afar, D.E.1    Goga, A.2    Cohen, L.3
  • 2
    • 0028286140 scopus 로고
    • Differential complementation of Bcr-Abl point mutants with c-Myc
    • D.E. Afar A. Goga J. McLaughlin Differential complementation of Bcr-Abl point mutants with c-Myc Science 264 1994 424
    • (1994) Science , vol.264 , pp. 424
    • Afar, D.E.1    Goga, A.2    McLaughlin, J.3
  • 4
    • 0028904209 scopus 로고
    • Long-term culture of chronic myelogenous leukemia marrow cells on stem cell factor–deficient stroma favors benign progenitors
    • R. Agarwal S. Doren B. Hicks C.E. Dunbar Long-term culture of chronic myelogenous leukemia marrow cells on stem cell factor–deficient stroma favors benign progenitors Blood 85 1995 1306 1312
    • (1995) Blood , vol.85 , pp. 1306-1312
    • Agarwal, R.1    Doren, S.2    Hicks, B.3    Dunbar, C.E.4
  • 5
    • 0029163251 scopus 로고
    • 14-3-3 proteins: Biological function and domain structure
    • A. Aitken D. Jones Y. Soneji 14-3-3 proteins: Biological function and domain structure Biochem Soc Trans 23 1995 605
    • (1995) Biochem Soc Trans , vol.23 , pp. 605
    • Aitken, A.1    Jones, D.2    Soneji, Y.3
  • 6
    • 0030064432 scopus 로고    scopus 로고
    • Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1
    • A. Aitken K. Moelling Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1 Oncogene 12 1996 609
    • (1996) Oncogene , vol.12 , pp. 609
    • Aitken, A.1    Moelling, K.2
  • 7
    • 0029041749 scopus 로고
    • UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: Improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia
    • N.C. Allan S.M. Richards P.C. Shepherd UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: Improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia Lancet 345 1995 1392 1397
    • (1995) Lancet , vol.345 , pp. 1392-1397
    • Allan, N.C.1    Richards, S.M.2    Shepherd, P.C.3
  • 8
    • 0025280860 scopus 로고
    • Human hematopoietic precursors in long term culture: Single CD34+ cells that lack detectable T cell, B cell and myeloid antigens produce multiple colony forming cells when cultured with marrow stromal cells
    • + cells that lack detectable T cell, B cell and myeloid antigens produce multiple colony forming cells when cultured with marrow stromal cells J Exp Med 172 1990 355 358
    • (1990) J Exp Med , vol.172 , pp. 355-358
    • Andrews, R.G.1    Singer, J.W.2    Bernstein, I.D.3
  • 9
    • 0027369850 scopus 로고
    • Autografting in chronic myeloid leukemia with cultured marrow: Update of the Vancouver Study
    • M.J. Barnett C.J. Eaves G.L. Phillips Autografting in chronic myeloid leukemia with cultured marrow: Update of the Vancouver Study Stem Cells 11 suppl 3 1993 64 66
    • (1993) Stem Cells , vol.11 , Issue.suppl 3 , pp. 64-66
    • Barnett, M.J.1    Eaves, C.J.2    Phillips, G.L.3
  • 10
    • 0024425525 scopus 로고
    • Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture
    • M.J. Barnett C.J. Eaves G.L. Phillips Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture Bone Marrow Transpl 4 1989 345 351
    • (1989) Bone Marrow Transpl , vol.4 , pp. 345-351
    • Barnett, M.J.1    Eaves, C.J.2    Phillips, G.L.3
  • 11
    • 0020972981 scopus 로고
    • Translocation of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukemia
    • C.R. Bartram deKlein A. A. Hagemeijer Translocation of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukemia Nature 306 1983 277 280
    • (1983) Nature , vol.306 , pp. 277-280
    • Bartram, C.R.1    deKlein, A.2    Hagemeijer, A.3
  • 12
    • 0026576937 scopus 로고
    • Isolation of a candidate human hematopoietic stem-cell population
    • C.M. Baum I.L. Weissman A.S. Tsukamoto Isolation of a candidate human hematopoietic stem-cell population Proc Natl Acad Sci USA 89 1992 2804 2808
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2804-2808
    • Baum, C.M.1    Weissman, I.L.2    Tsukamoto, A.S.3
  • 13
    • 0028256425 scopus 로고
    • Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
    • A. Bedi Zehnbauer B.A. Barber J.P. Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia Blood 83 1994 2038
    • (1994) Blood , vol.83 , pp. 2038
    • Bedi, A.1    B.A., Zehnbauer2    Barber, J.P.3
  • 14
    • 0029131231 scopus 로고
    • BCR-ABL–mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents
    • A. Bedi J.P. Barber G.C. Bedi BCR-ABL–mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents Blood 86 1995 1148 1155
    • (1995) Blood , vol.86 , pp. 1148-1155
    • Bedi, A.1    Barber, J.P.2    Bedi, G.C.3
  • 15
    • 0027942768 scopus 로고
    • Growth factor–mediated terminal differentiation of chronic myeloid leukemia
    • A. Bedi C.A. Griffin J.P. Barber Growth factor–mediated terminal differentiation of chronic myeloid leukemia Cancer Res 54 1994 5535 5538
    • (1994) Cancer Res , vol.54 , pp. 5535-5538
    • Bedi, A.1    Griffin, C.A.2    Barber, J.P.3
  • 16
    • 0022544401 scopus 로고
    • The chronic myelogenous leukemia–specific P210 protein is the product of the bcr/abl hybrid gene
    • Y. Ben-Neriah G.Q. Daley A.M. Mes-Masson The chronic myelogenous leukemia–specific P210 protein is the product of the bcr/abl hybrid gene Science 233 1986 212 215
    • (1986) Science , vol.233 , pp. 212-215
    • Ben-Neriah, Y.1    Daley, G.Q.2    Mes-Masson, A.M.3
  • 17
    • 0028966584 scopus 로고
    • Functional isolation and characterization of human hematopoietic stem cells
    • A.C. Berardi A. Wang J.D. Levine Functional isolation and characterization of human hematopoietic stem cells Science 267 1995 104 108
    • (1995) Science , vol.267 , pp. 104-108
    • Berardi, A.C.1    Wang, A.2    Levine, J.D.3
  • 18
    • 0025752491 scopus 로고
    • Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma
    • R.J. Berenson W.I. Bensinger R.S. Hill Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma Blood 77 1991 1717 1722
    • (1991) Blood , vol.77 , pp. 1717-1722
    • Berenson, R.J.1    Bensinger, W.I.2    Hill, R.S.3
  • 19
    • 0029010504 scopus 로고
    • Abnormalities of the bone marrow microenvironment in chronic myelogenous leukemia are related to malignant macrophages
    • R. Bhatia G. Dewald P. McGlave C.M. Verfaillie Abnormalities of the bone marrow microenvironment in chronic myelogenous leukemia are related to malignant macrophages Blood 85 1995 3636 3645
    • (1995) Blood , vol.85 , pp. 3636-3645
    • Bhatia, R.1    Dewald, G.2    McGlave, P.3    Verfaillie, C.M.4
  • 20
    • 0029888021 scopus 로고    scopus 로고
    • Interferon-α restores normal β1-integrin mediated negative regulation of chronic myelogenous leukemia progenitor proliferation
    • R. Bhatia J.B. McCarthy C.M. Verfaillie Interferon-α restores normal β1-integrin mediated negative regulation of chronic myelogenous leukemia progenitor proliferation Blood 87 suppl 1 1996 3883 3891
    • (1996) Blood , vol.87 , Issue.suppl 1 , pp. 3883-3891
    • Bhatia, R.1    McCarthy, J.B.2    Verfaillie, C.M.3
  • 21
    • 0029111697 scopus 로고
    • Interferon-α treatment of normal bone marrow stroma results in enhanced adhesion of CML hematopoietic progenitors via mechanisms involving MIP-1α
    • R. Bhatia P.B. McGlave C.M. Verfaillie Interferon-α treatment of normal bone marrow stroma results in enhanced adhesion of CML hematopoietic progenitors via mechanisms involving MIP-1α J Clin Invest 96 1995 931 939
    • (1995) J Clin Invest , vol.96 , pp. 931-939
    • Bhatia, R.1    McGlave, P.B.2    Verfaillie, C.M.3
  • 22
    • 6844242215 scopus 로고    scopus 로고
    • Decreased β1-integrin receptor capping in CML progenitors reflecting abnormal receptor cytoskeletal interactions is normalized by interferon-α
    • R. Bhatia H. Munthe C.M. Verfaillie Decreased β1-integrin receptor capping in CML progenitors reflecting abnormal receptor cytoskeletal interactions is normalized by interferon-α Blood 88 suppl 1 1996 2537a
    • (1996) Blood , vol.88 , Issue.suppl 1 , pp. 2537a
    • Bhatia, R.1    Munthe, H.2    Verfaillie, C.M.3
  • 23
    • 0008331309 scopus 로고
    • Inhibition of BCR-ABL expression by anti-sense oligonucleotides normalizes β1-integrin mediated adhesion and regulation of proliferation in chronic myelogenous leukemia
    • R. Bhatia C.M. Verfaillie Inhibition of BCR-ABL expression by anti-sense oligonucleotides normalizes β1-integrin mediated adhesion and regulation of proliferation in chronic myelogenous leukemia Blood 86 suppl 1 1995 1740a
    • (1995) Blood , vol.86 , Issue.suppl 1 , pp. 1740a
    • Bhatia, R.1    Verfaillie, C.M.2
  • 24
    • 85119461218 scopus 로고    scopus 로고
    • Inhibition of BCR-ABL tyrosine kinase activity with tyrphostin AG975 restores β1-integrin mediated regulation of hematopoietic progenitor proliferation in CML
    • R. Bhatia C.M. Verfaillie Inhibition of BCR-ABL tyrosine kinase activity with tyrphostin AG975 restores β1-integrin mediated regulation of hematopoietic progenitor proliferation in CML Blood 88 suppl 1 1996 2687a
    • (1996) Blood , vol.88 , Issue.suppl 1 , pp. 2687a
    • Bhatia, R.1    Verfaillie, C.M.2
  • 25
    • 0008331309 scopus 로고
    • Inhibition of BCR/ABL expression by anti-sense oligonucleotides normalizes β1-integrin mediated adhesion and regulation of proliferation in chronic myelogenous leukemia
    • R. Bhatia C.M. Verfaillie Inhibition of BCR/ABL expression by anti-sense oligonucleotides normalizes β1-integrin mediated adhesion and regulation of proliferation in chronic myelogenous leukemia Blood 86 suppl 1 1995 1740a
    • (1995) Blood , vol.86 , Issue.suppl 1 , pp. 1740a
    • Bhatia, R.1    Verfaillie, C.M.2
  • 26
    • 0028178976 scopus 로고
    • Interferon-α restores adhesion of malignant progenitors in CML by restoring β1 integrin function
    • R. Bhatia E. Wayner P. McGlave C.M. Verfaillie Interferon-α restores adhesion of malignant progenitors in CML by restoring β1 integrin function J Clin Invest 94 1994 384 391
    • (1994) J Clin Invest , vol.94 , pp. 384-391
    • Bhatia, R.1    Wayner, E.2    McGlave, P.3    Verfaillie, C.M.4
  • 27
    • 0019781901 scopus 로고
    • Regulation of erythroid cell differentiation by haemin
    • S.A. Bonanou-Tzedaki M. Sohi H.R. Arnstein Regulation of erythroid cell differentiation by haemin Cell Differ 10 1981 267 279
    • (1981) Cell Differ , vol.10 , pp. 267-279
    • Bonanou-Tzedaki, S.A.1    Sohi, M.2    Arnstein, H.R.3
  • 28
    • 0026500752 scopus 로고
    • The tetrapeptide AcSDKP, an inhibitor of the cell-cycle status for normal human hematopoietic progenitors, has no effect on leukemic cells
    • D. Bonnet R. Cesaire F. Lemoine The tetrapeptide AcSDKP, an inhibitor of the cell-cycle status for normal human hematopoietic progenitors, has no effect on leukemic cells Exp Hematol 20 1992 251 255
    • (1992) Exp Hematol , vol.20 , pp. 251-255
    • Bonnet, D.1    Cesaire, R.2    Lemoine, F.3
  • 29
    • 0027374114 scopus 로고
    • Direct and reversible inhibitory effect of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Seraspenide) on the growth of human CD34+ subpopulations in response to growth factors
    • D. Bonnet F.M. Lemoine S. Pontvert-Delucq Direct and reversible inhibitory effect of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Seraspenide) on the growth of human CD34+ subpopulations in response to growth factors Blood 82 1993 3307 3314
    • (1993) Blood , vol.82 , pp. 3307-3314
    • Bonnet, D.1    Lemoine, F.M.2    Pontvert-Delucq, S.3
  • 30
    • 0028229886 scopus 로고
    • Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family
    • C. Bovolenta P.H. Driggers M.S. Marks Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family Proc Natl Acad Sci USA 91 1994 5046 5050
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5046-5050
    • Bovolenta, C.1    Driggers, P.H.2    Marks, M.S.3
  • 31
    • 0023810743 scopus 로고
    • Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro
    • J. Brandt N. Baird L. Lu Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro J Clin Invest 82 1988 1017 1027
    • (1988) J Clin Invest , vol.82 , pp. 1017-1027
    • Brandt, J.1    Baird, N.2    Lu, L.3
  • 32
    • 0026703850 scopus 로고
    • Maintenance of Philadelphia-chromosome–positive progenitors in long-term marrow cultures from patients with advanced chronic myeloid leukemia
    • J.M. Brandwein I.D. Dube P. Laraya A. Keating Maintenance of Philadelphia-chromosome–positive progenitors in long-term marrow cultures from patients with advanced chronic myeloid leukemia Leukemia 6 1992 556 561
    • (1992) Leukemia , vol.6 , pp. 556-561
    • Brandwein, J.M.1    Dube, I.D.2    Laraya, P.3    Keating, A.4
  • 33
    • 0027471156 scopus 로고
    • Gene-marking to trace origin of relapse after autologous transplantation
    • M.K. Brenner D.R. Rill R.C. Moen Gene-marking to trace origin of relapse after autologous transplantation Lancet 341 1993 85 89
    • (1993) Lancet , vol.341 , pp. 85-89
    • Brenner, M.K.1    Rill, D.R.2    Moen, R.C.3
  • 35
    • 0024579528 scopus 로고
    • Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer
    • T.M. Browder J.S. Abrams P.M. Wong A.W. Nienhuis Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer Mol Cell Biol 9 1989 204 213
    • (1989) Mol Cell Biol , vol.9 , pp. 204-213
    • Browder, T.M.1    Abrams, J.S.2    Wong, P.M.3    Nienhuis, A.W.4
  • 36
    • 0010157031 scopus 로고
    • Suppressive effects of the chemokine family of cytokines on proliferation of normal and leukemic myeloid cell proliferation
    • H.E. Broxmeyer L. Benninger N. Hague Suppressive effects of the chemokine family of cytokines on proliferation of normal and leukemic myeloid cell proliferation Guigon M. The Negative Regulation of Hematopoiesis, vol 229. Colloque INSERM 1993 John Libbey Eurotext London 141
    • (1993) , pp. 141
    • Broxmeyer, H.E.1    Benninger, L.2    Hague, N.3
  • 37
    • 0025947125 scopus 로고
    • Macrophage inflammatory protein (MIP)-1 beta abrogates the capacity of MIP-1 alpha to suppress myeloid progenitor cell growth
    • H.E. Broxmeyer B. Sherry S. Cooper Macrophage inflammatory protein (MIP)-1 beta abrogates the capacity of MIP-1 alpha to suppress myeloid progenitor cell growth J Immunol 147 1991 2586 2594
    • (1991) J Immunol , vol.147 , pp. 2586-2594
    • Broxmeyer, H.E.1    Sherry, B.2    Cooper, S.3
  • 38
    • 0025195391 scopus 로고
    • Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells
    • H.E. Broxmeyer B. Sherry L. Lu Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells Blood 76 1990 1110 1116
    • (1990) Blood , vol.76 , pp. 1110-1116
    • Broxmeyer, H.E.1    Sherry, B.2    Lu, L.3
  • 39
    • 0023581632 scopus 로고
    • The role of T-cells in preventing relapse in chronic myelogenous leukemia
    • A. Butturini R.P. Gale The role of T-cells in preventing relapse in chronic myelogenous leukemia Bone Marrow Transpl 2 1987 351 354
    • (1987) Bone Marrow Transpl , vol.2 , pp. 351-354
    • Butturini, A.1    Gale, R.P.2
  • 40
    • 0025262141 scopus 로고
    • Clinical characteristics of the blast phase of chronic myelogenous leukemia
    • G.P. Canellos Clinical characteristics of the blast phase of chronic myelogenous leukemia Hematol Oncol Clin North Am 4 1990 359
    • (1990) Hematol Oncol Clin North Am , vol.4 , pp. 359
    • Canellos, G.P.1
  • 41
    • 0031459864 scopus 로고    scopus 로고
    • p62dok: A constitutively tyrosine-phosphorylated GAP-associated protein in chronic myelogenous leukemia
    • N. Caprino D. Wisniewski A. Strife p62dok: A constitutively tyrosine-phosphorylated GAP-associated protein in chronic myelogenous leukemia Cell 88 1997 197 204
    • (1997) Cell , vol.88 , pp. 197-204
    • Caprino, N.1    Wisniewski, D.2    Strife, A.3
  • 42
    • 3543021593 scopus 로고
    • Selective overshoot of Ph-negative blood hemopoietic cells after an intensive idarubicin-containing regimen and their repopulating capacity after reinfusion
    • A.M. Carella M. Podesta F. Grassoni Selective overshoot of Ph-negative blood hemopoietic cells after an intensive idarubicin-containing regimen and their repopulating capacity after reinfusion Journal of Hematotherapy 3 1994 199 202
    • (1994) Journal of Hematotherapy , vol.3 , pp. 199-202
    • Carella, A.M.1    Podesta, M.2    Grassoni, F.3
  • 43
    • 0029863169 scopus 로고    scopus 로고
    • Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
    • N. Carlesso D.A. Frank J.D. Griffin Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl J Exp Med 183 1996 811
    • (1996) J Exp Med , vol.183 , pp. 811
    • Carlesso, N.1    Frank, D.A.2    Griffin, J.D.3
  • 44
    • 0028006156 scopus 로고
    • Use of a temperature sensitive mutant to define biological effects of the p210BCR-ABL tyrosine kinase on proliferation of a factor dependent murine cell line
    • N. Carlesso J.D. Griffin B.J. Druker Use of a temperature sensitive mutant to define biological effects of the p210BCR-ABL tyrosine kinase on proliferation of a factor dependent murine cell line Oncogene 9 1994 149
    • (1994) Oncogene , vol.9 , pp. 149
    • Carlesso, N.1    Griffin, J.D.2    Druker, B.J.3
  • 45
    • 13344282746 scopus 로고    scopus 로고
    • Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias
    • C.E. Carow M. Levenstein S.H. Kaufmann Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias Blood 82 1996 1089 1096
    • (1996) Blood , vol.82 , pp. 1089-1096
    • Carow, C.E.1    Levenstein, M.2    Kaufmann, S.H.3
  • 46
    • 0026669189 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor modulation of the inhibitory effect of transforming growth factor-beta on normal and leukemic human hematopoietic progenitor cells
    • J.D. Cashman A.C. Eaves C.J. Eaves Granulocyte-macrophage colony-stimulating factor modulation of the inhibitory effect of transforming growth factor-beta on normal and leukemic human hematopoietic progenitor cells Leukemia 6 1992 886 892
    • (1992) Leukemia , vol.6 , pp. 886-892
    • Cashman, J.D.1    Eaves, A.C.2    Eaves, C.J.3
  • 47
    • 0028022981 scopus 로고
    • The tetrapeptide AcSDKP specifically blocks the cycling of primitive normal but not leukemic progenitors in long-term culture: Evidence for an indirect mechanism
    • J.D. Cashman A.C. Eaves C.J. Eaves The tetrapeptide AcSDKP specifically blocks the cycling of primitive normal but not leukemic progenitors in long-term culture: Evidence for an indirect mechanism Blood 84 1994 1534 1542
    • (1994) Blood , vol.84 , pp. 1534-1542
    • Cashman, J.D.1    Eaves, A.C.2    Eaves, C.J.3
  • 48
    • 0025166472 scopus 로고
    • Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta
    • J.D. Cashman A.C. Eaves E.W. Raines Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta Blood 75 1990 96 101
    • (1990) Blood , vol.75 , pp. 96-101
    • Cashman, J.D.1    Eaves, A.C.2    Raines, E.W.3
  • 49
    • 0028720895 scopus 로고
    • Regulatory activity of endogenous MIP-1 alpha in long-term cultures of human marrow
    • J.D. Cashman A.C. Eaves S. Wolpe C.J. Eaves Regulatory activity of endogenous MIP-1 alpha in long-term cultures of human marrow Prog Clin Biol Res 389 1994 261 168
    • (1994) Prog Clin Biol Res , vol.389 , pp. 261-168
    • Cashman, J.D.1    Eaves, A.C.2    Wolpe, S.3    Eaves, C.J.4
  • 50
    • 0020085766 scopus 로고
    • Characteristics of bone marrow fibroblast colony-forming cells [CFU-F] and their progeny in patients with myeloproliferative disorders
    • H. Castro-Malaspina R.E. Gay S.C. Jhanwar Characteristics of bone marrow fibroblast colony-forming cells [CFU-F] and their progeny in patients with myeloproliferative disorders Blood 59 1982 1046 1054
    • (1982) Blood , vol.59 , pp. 1046-1054
    • Castro-Malaspina, H.1    Gay, R.E.2    Jhanwar, S.C.3
  • 51
    • 15444342095 scopus 로고
    • Studies on the microenvironment in human chronic myelogenous leukemia
    • H. Castro-Malaspina Laver J. S. Jhanwar Studies on the microenvironment in human chronic myelogenous leukemia Exp Hematol 12 1984 470 478
    • (1984) Exp Hematol , vol.12 , pp. 470-478
    • Castro-Malaspina, H.1    Laver, J.2    Jhanwar, S.3
  • 53
    • 0028822407 scopus 로고
    • Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia
    • R.C. Chasty G.S. Lucas P.J. Owen-Lynch Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia Blood 86 1995 4270 4277
    • (1995) Blood , vol.86 , pp. 4270-4277
    • Chasty, R.C.1    Lucas, G.S.2    Owen-Lynch, P.J.3
  • 54
    • 0027938974 scopus 로고
    • Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
    • H.C. Chen J.L. Guan Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase Proc Natl Acad Sci USA 91 1994 10148
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10148
    • Chen, H.C.1    Guan, J.L.2
  • 55
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • E.A. Clark J.S. Brugge Integrins and signal transduction pathways: The road taken Science 268 1995 233
    • (1995) Science , vol.268 , pp. 233
    • Clark, E.A.1    Brugge, J.S.2
  • 57
    • 0027517983 scopus 로고
    • Linkage of proliferative and maturational abnormalities in chronic myelogenous leukemia and relevance to treatment
    • B. Clarkson A. Strife Linkage of proliferative and maturational abnormalities in chronic myelogenous leukemia and relevance to treatment Leukemia 7 1993 1683
    • (1993) Leukemia , vol.7 , pp. 1683
    • Clarkson, B.1    Strife, A.2
  • 58
    • 0029895933 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia: A review
    • J.E. Cortes M. Talpaz H. Kantarjian Chronic myelogenous leukemia: A review Am J Med 100 1996 555 570
    • (1996) Am J Med , vol.100 , pp. 555-570
    • Cortes, J.E.1    Talpaz, M.2    Kantarjian, H.3
  • 59
    • 0028980342 scopus 로고
    • Structural and signaling requirements for BCR-ABL–mediated transformation and inhibition of apoptosis
    • D. Cortez L. Kadlec A.M. Pendergast Structural and signaling requirements for BCR-ABL–mediated transformation and inhibition of apoptosis Mol Cell Biol 15 1995 5531
    • (1995) Mol Cell Biol , vol.15 , pp. 5531
    • Cortez, D.1    Kadlec, L.2    Pendergast, A.M.3
  • 60
    • 0029094008 scopus 로고
    • BCR-ABL: An anti-apoptosis gene in chronic myelogenous leukemia
    • T.G. Cotter BCR-ABL: An anti-apoptosis gene in chronic myelogenous leukemia Leuk Lymphoma 1 1995 231
    • (1995) Leuk Lymphoma , vol.1 , pp. 231
    • Cotter, T.G.1
  • 61
    • 0020581621 scopus 로고
    • Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Philadelphia chromosome–positive chronic myelogenous leukemia
    • L. Coulombel D.K. Kalousek C.J. Eaves Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Philadelphia chromosome–positive chronic myelogenous leukemia N Engl J Med 308 1983 1493 1498
    • (1983) N Engl J Med , vol.308 , pp. 1493-1498
    • Coulombel, L.1    Kalousek, D.K.2    Eaves, C.J.3
  • 62
    • 0030067021 scopus 로고    scopus 로고
    • Assembly of focal adhesions: Progress, paradigms, and portents
    • S.W. Craig R.P. Johnson Assembly of focal adhesions: Progress, paradigms, and portents Curr Opin Cell Biol 8 1996 74 85
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 74-85
    • Craig, S.W.1    Johnson, R.P.2
  • 63
    • 0027406463 scopus 로고
    • Expression of Thy-1 on human hematopoietic progenitor cells
    • W. Craig R. Kay R.L. Cutler P.M. Lansdorp Expression of Thy-1 on human hematopoietic progenitor cells J Exp Med 177 1993 1331 1342
    • (1993) J Exp Med , vol.177 , pp. 1331-1342
    • Craig, W.1    Kay, R.2    Cutler, R.L.3    Lansdorp, P.M.4
  • 64
    • 0001044842 scopus 로고
    • Transformation of an interleukin 3–dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein
    • G.Q. Daley D. Baltimore Transformation of an interleukin 3–dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein Proc Natl Acad Sci USA 85 1988 9312
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9312
    • Daley, G.Q.1    Baltimore, D.2
  • 66
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210BCR-ABL gene of the Philadelphia chromosome
    • BCR-ABL gene of the Philadelphia chromosome Science 247 1990 824 829
    • (1990) Science , vol.247 , pp. 824-829
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 67
    • 0026503597 scopus 로고
    • Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line
    • G.Q. Daley Van Etten R.A. P.K. Jackson Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line Mol Cell Biol 12 1992 1864 1831
    • (1992) Mol Cell Biol , vol.12 , pp. 1864-1831
    • Daley, G.Q.1    Van Etten, R.A.2    Jackson, P.K.3
  • 68
    • 0028817880 scopus 로고
    • Jak-STAT signaling induced by the v-abl oncogene
    • N.N. Danial A. Pernis P.B. Rothman Jak-STAT signaling induced by the v-abl oncogene Science 269 1995 1875 1878
    • (1995) Science , vol.269 , pp. 1875-1878
    • Danial, N.N.1    Pernis, A.2    Rothman, P.B.3
  • 69
    • 0028936647 scopus 로고
    • Absence of point mutations in the extracellular domain of the alpha subunit of the GM-CSF receptor in a series of patients with acute myeloid leukemia (AML)
    • J. Decker W. Fiedler A. Samalecos D.K. Hossfeld Absence of point mutations in the extracellular domain of the alpha subunit of the GM-CSF receptor in a series of patients with acute myeloid leukemia (AML) Leukemia 9 1995 185 188
    • (1995) Leukemia , vol.9 , pp. 185-188
    • Decker, J.1    Fiedler, W.2    Samalecos, A.3    Hossfeld, D.K.4
  • 70
    • 0029164951 scopus 로고
    • Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia
    • R. de Jong ten Hoeve J. N. Heisterkamp Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia J Biol Chem 270 1995 21468
    • (1995) J Biol Chem , vol.270 , pp. 21468
    • de Jong, R.1    ten Hoeve, J.2    Heisterkamp, N.3
  • 71
    • 85041132416 scopus 로고
    • Genetic marking shows that Ph+ cells present in autologous marrow of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplants in CML
    • A.B. Deisseroth Z. Zhifei D. Claxton Genetic marking shows that Ph+ cells present in autologous marrow of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplants in CML Blood 83 1994 3068 3076
    • (1994) Blood , vol.83 , pp. 3068-3076
    • Deisseroth, A.B.1    Zhifei, Z.2    Claxton, D.3
  • 72
    • 85088679778 scopus 로고    scopus 로고
    • CD34+HLA-DR- cells in chronic phase CML, but not in more advanced phase CML, are polyclonal
    • M. Delforge M.A. Boogaerts P.B. McGlave C.M. Verfaillie CD34+HLA-DR- cells in chronic phase CML, but not in more advanced phase CML, are polyclonal Blood 88 suppl 1 1996 907a
    • (1996) Blood , vol.88 , Issue.suppl 1 , pp. 907a
    • Delforge, M.1    Boogaerts, M.A.2    McGlave, P.B.3    Verfaillie, C.M.4
  • 74
    • 0029077960 scopus 로고
    • Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predicts a rapid platelet recovery after peripheral blood stem cell transplantation
    • M.W. Dercksen W.R. Gerritsen S. Rodenhuis Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predicts a rapid platelet recovery after peripheral blood stem cell transplantation Blood 85 1995 3313
    • (1995) Blood , vol.85 , pp. 3313
    • Dercksen, M.W.1    Gerritsen, W.R.2    Rodenhuis, S.3
  • 75
    • 0029560878 scopus 로고
    • Differential effect of type I interferons on hematopoietic progenitor cells: Failure of interferons to inhibit IL-3-stimulated normal and CML myeloid progenitors
    • D. Despres J. Goldschmitt W.E. Aulitzky Differential effect of type I interferons on hematopoietic progenitor cells: Failure of interferons to inhibit IL-3-stimulated normal and CML myeloid progenitors Exp Hematol 23 1995 1431 1438
    • (1995) Exp Hematol , vol.23 , pp. 1431-1438
    • Despres, D.1    Goldschmitt, J.2    Aulitzky, W.E.3
  • 76
    • 0027944916 scopus 로고
    • Granulocyte colony stimulating factor: From laboratory bench to clinical use
    • T.M. Dexter Granulocyte colony stimulating factor: From laboratory bench to clinical use Eur J Cancer 30A suppl 3 1994 S15 S19
    • (1994) Eur J Cancer , vol.30A , Issue.suppl 3 , pp. S15-S19
    • Dexter, T.M.1
  • 77
    • 0025038410 scopus 로고
    • BCR-ABL and BCR proteins: Biochemical characterization and localization
    • S. Dhut T. Chaplin B.D. Young BCR-ABL and BCR proteins: Biochemical characterization and localization Leukemia 4 1990 745
    • (1990) Leukemia , vol.4 , pp. 745
    • Dhut, S.1    Chaplin, T.2    Young, B.D.3
  • 78
    • 0028932038 scopus 로고
    • BCR-ABL, ABL-BCR, BCR, and ABL genes are all expressed in individual granulocyte-macrophage colony-forming unit colonies derived from blood of patients with chronic myeloid leukemia
    • J. Diamond J.M. Goldman J.V. Melo BCR-ABL, ABL-BCR, BCR, and ABL genes are all expressed in individual granulocyte-macrophage colony-forming unit colonies derived from blood of patients with chronic myeloid leukemia Blood 85 1995 2171 2175
    • (1995) Blood , vol.85 , pp. 2171-2175
    • Diamond, J.1    Goldman, J.M.2    Melo, J.V.3
  • 79
    • 0025873083 scopus 로고
    • Bcr encodes a GTPase-activating protein for p21rac
    • D. Diekmann S. Brill M.D. Garrett Bcr encodes a GTPase-activating protein for p21rac Nature 351 1991 400 402
    • (1991) Nature , vol.351 , pp. 400-402
    • Diekmann, D.1    Brill, S.2    Garrett, M.D.3
  • 80
    • 0028337822 scopus 로고
    • Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34
    • D. DiGiusto S. Chen J. Combs Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34 Blood 84 1994 421 432
    • (1994) Blood , vol.84 , pp. 421-432
    • DiGiusto, D.1    Chen, S.2    Combs, J.3
  • 81
    • 0025761954 scopus 로고
    • Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte “homing” receptor expressed by hemopoietic cells
    • G.J. Dougherty P.M. Lansdorp D.L. Cooper R.K. Humphries Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte “homing” receptor expressed by hemopoietic cells J Exp Med 174 1991 1 5
    • (1991) J Exp Med , vol.174 , pp. 1-5
    • Dougherty, G.J.1    Lansdorp, P.M.2    Cooper, D.L.3    Humphries, R.K.4
  • 82
    • 0027160827 scopus 로고
    • Potential mechanisms of action of interferon-alpha in CML
    • C. Dowding M. Gordon A.P. Guo Potential mechanisms of action of interferon-alpha in CML Leuk Lymphoma 11 suppl 1 1993 185 191
    • (1993) Leuk Lymphoma , vol.11 , Issue.suppl 1 , pp. 185-191
    • Dowding, C.1    Gordon, M.2    Guo, A.P.3
  • 83
    • 0025868121 scopus 로고
    • Interferon-alpha overrides the deficient adhesion of chronic myeloid leukemia primitive progenitor cells to bone marrow stromal cells
    • C. Dowding A.P. Guo J. Osterholz Interferon-alpha overrides the deficient adhesion of chronic myeloid leukemia primitive progenitor cells to bone marrow stromal cells Blood 78 1991 499
    • (1991) Blood , vol.78 , pp. 499
    • Dowding, C.1    Guo, A.P.2    Osterholz, J.3
  • 84
    • 0023944263 scopus 로고
    • Increased DR antigen expression by committed hemopoietic progenitor cells but not primitive progenitor cells in chronic myeloid leukemia
    • C.R. Dowding M.Y. Gordon J.M. Goldman Increased DR antigen expression by committed hemopoietic progenitor cells but not primitive progenitor cells in chronic myeloid leukemia Exp Hematol 16 1988 171 175
    • (1988) Exp Hematol , vol.16 , pp. 171-175
    • Dowding, C.R.1    Gordon, M.Y.2    Goldman, J.M.3
  • 85
    • 0030002950 scopus 로고    scopus 로고
    • Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells
    • H.G. Drexler Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells Leukemia 10 1996 588 599
    • (1996) Leukemia , vol.10 , pp. 588-599
    • Drexler, H.G.1
  • 86
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • B.J. Druker S. Tamara E. Buchdunger Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells Nature Medicine 2 1996 561
    • (1996) Nature Medicine , vol.2 , pp. 561
    • Druker, B.J.1    Tamara, S.2    Buchdunger, E.3
  • 87
    • 0028206875 scopus 로고
    • Interleukin-11, a multifunctional growth factor derived from the hematopoietic microenvironment
    • X.X. Du D.A. Williams Interleukin-11, a multifunctional growth factor derived from the hematopoietic microenvironment Blood 83 1994 2023 2030
    • (1994) Blood , vol.83 , pp. 2023-2030
    • Du, X.X.1    Williams, D.A.2
  • 88
    • 0021250702 scopus 로고
    • Cytogenetic studies of early myeloid progenitor compartments in Ph1-positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients
    • I.D. Dube D.K. Kalousek L. Coulombel Cytogenetic studies of early myeloid progenitor compartments in Ph1-positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients Blood 63 1984 1172 1177
    • (1984) Blood , vol.63 , pp. 1172-1177
    • Dube, I.D.1    Kalousek, D.K.2    Coulombel, L.3
  • 89
    • 0026656723 scopus 로고
    • Demonstration of stem cell inhibition and myeloprotective effects of SCI/rhMIP1 alpha in vivo
    • D.J. Dunlop E.G. Wright S. Lorimore Demonstration of stem cell inhibition and myeloprotective effects of SCI/rhMIP1 alpha in vivo Blood 79 1992 2221 2225
    • (1992) Blood , vol.79 , pp. 2221-2225
    • Dunlop, D.J.1    Wright, E.G.2    Lorimore, S.3
  • 90
    • 0022442182 scopus 로고
    • Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells
    • A.C. Eaves J.D. Cashman L.A. Gaboury Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells Proc Natl Acad Sci USA 83 1986 5306 5310
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5306-5310
    • Eaves, A.C.1    Cashman, J.D.2    Gaboury, L.A.3
  • 91
    • 0018659319 scopus 로고
    • Abnormalities in the erythroid compartment in patients with chronic myeloid leukemia
    • A.C. Eaves C.J. Eaves Abnormalities in the erythroid compartment in patients with chronic myeloid leukemia Exp Haematol 7 1977 65 75
    • (1977) Exp Haematol , vol.7 , pp. 65-75
    • Eaves, A.C.1    Eaves, C.J.2
  • 92
    • 0025880646 scopus 로고
    • Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
    • C.J. Eaves J.D. Cashman R.J. Kay Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer Blood 78 1991 110 117
    • (1991) Blood , vol.78 , pp. 110-117
    • Eaves, C.J.1    Cashman, J.D.2    Kay, R.J.3
  • 93
    • 0027146639 scopus 로고
    • Unresponsiveness of primitive chronic mycloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells
    • C.J. Eaves J.D. Cashman S.D. Wolpe A.C. Eaves Unresponsiveness of primitive chronic mycloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells Proc Natl Acad Sci USA 90 1993 12015 12019
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 12015-12019
    • Eaves, C.J.1    Cashman, J.D.2    Wolpe, S.D.3    Eaves, A.C.4
  • 94
    • 0029091775 scopus 로고
    • Persistence of BCR/ABL mRNA-expressing bone-marrow cells in patients with chronic myelogenous leukemia in complete cytogenetic remission induced by interferon-alpha therapy
    • F. Eberle Y. Toiron J. Camerlo Persistence of BCR/ABL mRNA-expressing bone-marrow cells in patients with chronic myelogenous leukemia in complete cytogenetic remission induced by interferon-alpha therapy Leuk Lymph 18 1995 153 157
    • (1995) Leuk Lymph , vol.18 , pp. 153-157
    • Eberle, F.1    Toiron, Y.2    Camerlo, J.3
  • 95
    • 0002559045 scopus 로고    scopus 로고
    • The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia
    • R.S. Fernandes A.M. Gorman A. McGahon The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia Leukemia 10 suppl 2 1996 s17
    • (1996) Leukemia , vol.10 , Issue.suppl 2 , pp. s17
    • Fernandes, R.S.1    Gorman, A.M.2    McGahon, A.3
  • 96
    • 0017653321 scopus 로고
    • Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage
    • P.J. Fialkow R.J. Jacobson T.H. Papayannopoulou Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage Am J Med 63 1977 125 130
    • (1977) Am J Med , vol.63 , pp. 125-130
    • Fialkow, P.J.1    Jacobson, R.J.2    Papayannopoulou, T.H.3
  • 97
    • 0026462844 scopus 로고
    • Specific changes of Ras GTPase-activating protein (GAP) and a GAP-associated p62 protein during calcium-induced keratinocyte differentiation
    • E. Filvaroff E. Calautti F. McCormick G.P. Dotto Specific changes of Ras GTPase-activating protein (GAP) and a GAP-associated p62 protein during calcium-induced keratinocyte differentiation Mol Cell Biol 12 1992 5319 5328
    • (1992) Mol Cell Biol , vol.12 , pp. 5319-5328
    • Filvaroff, E.1    Calautti, E.2    McCormick, F.3    Dotto, G.P.4
  • 98
    • 0029096232 scopus 로고
    • Human allogeneic stem cell maintenance and differentiation in a long-term multilineage SCID-hu graft
    • C.C. Fraser H. Kaneshima G. Hansteen Human allogeneic stem cell maintenance and differentiation in a long-term multilineage SCID-hu graft Blood 86 1995 1680 1693
    • (1995) Blood , vol.86 , pp. 1680-1693
    • Fraser, C.C.1    Kaneshima, H.2    Hansteen, G.3
  • 99
    • 0017327797 scopus 로고
    • Inhibition of CFU entry into cycle by a bone marrow extract
    • E. Frindel M. Guigon Inhibition of CFU entry into cycle by a bone marrow extract Exp Hematol 5 1977 74 76
    • (1977) Exp Hematol , vol.5 , pp. 74-76
    • Frindel, E.1    Guigon, M.2
  • 100
    • 14444270843 scopus 로고
    • Positive and negative effects of different epitope-specific anti-CD44 antibodies on stromal cell-dependent hematopoiesis
    • S. Ghaffari G. Dougherty C.J. Eaves Positive and negative effects of different epitope-specific anti-CD44 antibodies on stromal cell-dependent hematopoiesis Blood 87 1995 1217a
    • (1995) Blood , vol.87 , pp. 1217a
    • Ghaffari, S.1    Dougherty, G.2    Eaves, C.J.3
  • 101
    • 0028820579 scopus 로고
    • Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia
    • S. Ghaffari G.J. Dougherty P.M. Lansdorp Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia Blood 86 1995 2976 2985
    • (1995) Blood , vol.86 , pp. 2976-2985
    • Ghaffari, S.1    Dougherty, G.J.2    Lansdorp, P.M.3
  • 102
    • 0027506288 scopus 로고
    • Efficient transplantation of BCR-ABL–induced chronic myelogenous leukemia-like syndrome in mice
    • M.L. Gishizky J. Johnson-White O.N. Witte Efficient transplantation of BCR-ABL–induced chronic myelogenous leukemia-like syndrome in mice Proc Natl Acad Sci USA 90 1993 3755
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3755
    • Gishizky, M.L.1    Johnson-White, J.2    Witte, O.N.3
  • 103
    • 0026608119 scopus 로고
    • Initiation of dysregulated growth of multipotent progenitor cells by bcr-abl in vitro
    • M.L. Gishizky O.N. Witte Initiation of dysregulated growth of multipotent progenitor cells by bcr-abl in vitro Science 256 1992 836
    • (1992) Science , vol.256 , pp. 836
    • Gishizky, M.L.1    Witte, O.N.2
  • 104
    • 0029087475 scopus 로고
    • Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene
    • A. Goga J. McLaughlin D.E. Afar Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene Cell 82 1995 981
    • (1995) Cell , vol.82 , pp. 981
    • Goga, A.1    McLaughlin, J.2    Afar, D.E.3
  • 105
    • 0018930411 scopus 로고
    • Circulating granulocytic and erythroid progenitor cells in chronic granulocytic leukemia
    • J.M. Goldman F. Shiota K.H. Th'ng K.H. Orchard Circulating granulocytic and erythroid progenitor cells in chronic granulocytic leukemia Br J Haematol 46 1980 7 13
    • (1980) Br J Haematol , vol.46 , pp. 7-13
    • Goldman, J.M.1    Shiota, F.2    Th'ng, K.H.3    Orchard, K.H.4
  • 106
    • 0023270373 scopus 로고
    • Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia
    • M.Y. Gordon C.R. Dowding G.P. Riley Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia Nature 328 1987 342 344
    • (1987) Nature , vol.328 , pp. 342-344
    • Gordon, M.Y.1    Dowding, C.R.2    Riley, G.P.3
  • 107
    • 0029116650 scopus 로고
    • Probability of progenitor renewal (PPR) and production of clonogenic progeny (CFU-GM) by primitive adherent progenitor cells in adult human one marrow and umbilical cord blood
    • M.Y. Gordon J.L. Lewis M.A. Scott Probability of progenitor renewal (PPR) and production of clonogenic progeny (CFU-GM) by primitive adherent progenitor cells in adult human one marrow and umbilical cord blood Br J Haematol 90 1995 744 749
    • (1995) Br J Haematol , vol.90 , pp. 744-749
    • Gordon, M.Y.1    Lewis, J.L.2    Scott, M.A.3
  • 108
    • 0024207601 scopus 로고
    • Heparan sulfate is necessary for adhesive interactions between human early hemopoietic progenitor cells and the extracellular matrix of the marrow microenvironment
    • M.Y. Gordon G.P. Riley D. Clarke Heparan sulfate is necessary for adhesive interactions between human early hemopoietic progenitor cells and the extracellular matrix of the marrow microenvironment Leukemia 2 1988 804 809
    • (1988) Leukemia , vol.2 , pp. 804-809
    • Gordon, M.Y.1    Riley, G.P.2    Clarke, D.3
  • 109
    • 0027279318 scopus 로고
    • Cell biology of CML—a model linking the chronic and terminal phases
    • M.Y. Gordon Cell biology of CML—a model linking the chronic and terminal phases Leuk Lymphoma 11 suppl 1 1993 93 100
    • (1993) Leuk Lymphoma , vol.11 , Issue.suppl 1 , pp. 93-100
    • Gordon, M.Y.1
  • 110
    • 0029015273 scopus 로고
    • Steel factor supports the cycling of isolated human CD34+ cells in the absence of other growth factors
    • S.D. Gore S. Amin L.J. Weng C.I. Civin Steel factor supports the cycling of isolated human CD34+ cells in the absence of other growth factors Exp Hematol 23 1995 413 421
    • (1995) Exp Hematol , vol.23 , pp. 413-421
    • Gore, S.D.1    Amin, S.2    Weng, L.J.3    Civin, C.I.4
  • 111
    • 0026652475 scopus 로고
    • Effect of mast cell growth factor (c-kit ligand) on clonogenic leukemic precursor cells
    • H.M. Goselink D.E. Williams W.E. Fibbe Effect of mast cell growth factor (c-kit ligand) on clonogenic leukemic precursor cells Blood 80 1992 750 757
    • (1992) Blood , vol.80 , pp. 750-757
    • Goselink, H.M.1    Williams, D.E.2    Fibbe, W.E.3
  • 112
    • 0020056396 scopus 로고
    • Growth characteristics of leukemic and normal hematopoietic cells in Ph1 + chronic myelogenous leukemia and effects of intensive treatment
    • T. Goto M. Nishikori Z. Arlin Growth characteristics of leukemic and normal hematopoietic cells in Ph1 + chronic myelogenous leukemia and effects of intensive treatment Blood 59 1982 793 808
    • (1982) Blood , vol.59 , pp. 793-808
    • Goto, T.1    Nishikori, M.2    Arlin, Z.3
  • 113
    • 0028889810 scopus 로고
    • Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein
    • A. Gotoh K. Miyazawa K. Ohyashiki Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein Exp Hematol 23 1995 1153
    • (1995) Exp Hematol , vol.23 , pp. 1153
    • Gotoh, A.1    Miyazawa, K.2    Ohyashiki, K.3
  • 114
    • 0025355270 scopus 로고
    • Identification and characterization of an inhibitor of haemopoietic stem cell proliferation
    • G.J. Graham E.G. Wright R. Hewick Identification and characterization of an inhibitor of haemopoietic stem cell proliferation Nature 344 1990 442 444
    • (1990) Nature , vol.344 , pp. 442-444
    • Graham, G.J.1    Wright, E.G.2    Hewick, R.3
  • 115
    • 0018200319 scopus 로고
    • Cytogenetics of fibroblastic colonies in Ph1-positive chronic myelogenous leukemia
    • B.R. Greenberg F.D. Wilson L. Woo H.M. Jenks Cytogenetics of fibroblastic colonies in Ph1-positive chronic myelogenous leukemia Blood 51 1978 1039 1044
    • (1978) Blood , vol.51 , pp. 1039-1044
    • Greenberg, B.R.1    Wilson, F.D.2    Woo, L.3    Jenks, H.M.4
  • 116
    • 0026706135 scopus 로고
    • Is the marrow stroma of AML patients a “leukemic” stroma?
    • J.S. Greenberger Is the marrow stroma of AML patients a “leukemic” stroma? Exp Hematol 20 1992 1041 1042
    • (1992) Exp Hematol , vol.20 , pp. 1041-1042
    • Greenberger, J.S.1
  • 117
    • 0025902224 scopus 로고
    • Effects of small peptidic inhibitors of murine stem cells on human normal and malignant cells
    • M. Guigon D. Bonnet R. Cesaire Effects of small peptidic inhibitors of murine stem cells on human normal and malignant cells Ann NY Acad Sci 628 1991 105 114
    • (1991) Ann NY Acad Sci , vol.628 , pp. 105-114
    • Guigon, M.1    Bonnet, D.2    Cesaire, R.3
  • 118
    • 8944262829 scopus 로고    scopus 로고
    • Interaction of the receptor tyrosine kinase p145c-kit with the p210bcr/abl kinase in myeloid cells
    • M. Hallek S. Danhauser-Riedl R. Herbst Interaction of the receptor tyrosine kinase p145c-kit with the p210bcr/abl kinase in myeloid cells Br J Haematol 94 1996 5 16
    • (1996) Br J Haematol , vol.94 , pp. 5-16
    • Hallek, M.1    Danhauser-Riedl, S.2    Herbst, R.3
  • 119
    • 0028932435 scopus 로고
    • Association of phosphatidylinositol 3-kinase with SHC in chronic myelogeneous leukemia cells
    • D. Harrison-Findik M. Susa L. Varticovski Association of phosphatidylinositol 3-kinase with SHC in chronic myelogeneous leukemia cells Oncogene 10 1995 1385
    • (1995) Oncogene , vol.10 , pp. 1385
    • Harrison-Findik, D.1    Susa, M.2    Varticovski, L.3
  • 120
    • 0028170517 scopus 로고
    • Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group
    • R. Hehlmann H. Heimpel J. Hasford Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group Blood 84 1994 4064 4077
    • (1994) Blood , vol.84 , pp. 4064-4077
    • Hehlmann, R.1    Heimpel, H.2    Hasford, J.3
  • 121
    • 0029941463 scopus 로고    scopus 로고
    • Apoptosis and chemotherapy resistance
    • J.A. Hickman Apoptosis and chemotherapy resistance Eur J Cancer 32A 1996 921
    • (1996) Eur J Cancer , vol.32A , pp. 921
    • Hickman, J.A.1
  • 122
    • 0024424628 scopus 로고
    • Bone marrow stromal cells in myeloproliferative disorders
    • J. Hirata H. Takahira S. Kaneko Bone marrow stromal cells in myeloproliferative disorders Acta Haematol 82 1989 35 39
    • (1989) Acta Haematol , vol.82 , pp. 35-39
    • Hirata, J.1    Takahira, H.2    Kaneko, S.3
  • 123
    • 0029991362 scopus 로고    scopus 로고
    • Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins
    • E. Hirsch A. Iglesias A.J. Potocnik Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins Nature 380 1996 171
    • (1996) Nature , vol.380 , pp. 171
    • Hirsch, E.1    Iglesias, A.2    Potocnik, A.J.3
  • 125
    • 0027442795 scopus 로고
    • The in vitro and in vivo effects of stem cell factor on human hematopoiesis
    • R. Hoffman J. Tong J. Brandt The in vitro and in vivo effects of stem cell factor on human hematopoiesis Stem Cells 11 suppl 2 1993 76 82
    • (1993) Stem Cells , vol.11 , Issue.suppl 2 , pp. 76-82
    • Hoffman, R.1    Tong, J.2    Brandt, J.3
  • 126
    • 16044369709 scopus 로고    scopus 로고
    • Immunodeficiency and chronic myelogenous leukemia–like syndrome in mice with a targeted mutation of the ICSBP gene
    • T. Holtschke J. Lohler Y. Kanno Immunodeficiency and chronic myelogenous leukemia–like syndrome in mice with a targeted mutation of the ICSBP gene Cell 87 1996 307 317
    • (1996) Cell , vol.87 , pp. 307-317
    • Holtschke, T.1    Lohler, J.2    Kanno, Y.3
  • 127
    • 0027443831 scopus 로고
    • Contrasting effects of rh-MIP-1 alpha and TGF-beta on chronic myeloid leukemia progenitors in vitro
    • T.L. Holyoake M.G. Freshney A.M. Sproul Contrasting effects of rh-MIP-1 alpha and TGF-beta on chronic myeloid leukemia progenitors in vitro Stem Cells 11 suppl 3 1993 122 128
    • (1993) Stem Cells , vol.11 , Issue.suppl 3 , pp. 122-128
    • Holyoake, T.L.1    Freshney, M.G.2    Sproul, A.M.3
  • 128
    • 0028235799 scopus 로고
    • Molecular properties of the chemokine receptor family
    • R. Horuk Molecular properties of the chemokine receptor family Trends Pharmacol Sci 15 1994 159 165
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 159-165
    • Horuk, R.1
  • 129
    • 85119466934 scopus 로고    scopus 로고
    • R Hurley, JB McCarthy, CM Verfaillie, Clustering of integrins results in proliferation inhibition of committed hematopoietic progenitors through mechanisms involving the cell cytoskeleton. Exp Hematol, in press
  • 130
    • 0029087659 scopus 로고
    • Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation
    • R.W. Hurley J.B. McCarthy C.M. Verfaillie Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation J Clin Invest 96 1995 511 519
    • (1995) J Clin Invest , vol.96 , pp. 511-519
    • Hurley, R.W.1    McCarthy, J.B.2    Verfaillie, C.M.3
  • 131
    • 0028933799 scopus 로고
    • Signaling through the hematopoietic cytokine receptors
    • J.N. Ihle B.A. Witthuhn F.W. Quelle Signaling through the hematopoietic cytokine receptors Annu Rev Immunol 13 1995 369
    • (1995) Annu Rev Immunol , vol.13 , pp. 369
    • Ihle, J.N.1    Witthuhn, B.A.2    Quelle, F.W.3
  • 132
    • 0028027712 scopus 로고
    • Growth of erythroid colonies in chronic myelogenous leukemia is independent of erythropoietin only in the presence of steel factor
    • C. Issaad W. Vainchenker Growth of erythroid colonies in chronic myelogenous leukemia is independent of erythropoietin only in the presence of steel factor Blood 84 1994 3447 3456
    • (1994) Blood , vol.84 , pp. 3447-3456
    • Issaad, C.1    Vainchenker, W.2
  • 133
    • 0028812716 scopus 로고
    • Chronic myeloid leukemia, BCR/ABL transcript, response to alpha-interferon and survival
    • Italian Cooperative Study Group on Chronic Myeloid Leukemia Chronic myeloid leukemia, BCR/ABL transcript, response to alpha-interferon and survival Leukemia. 9 1995 1648 1652
    • (1995) Leukemia. , vol.9 , pp. 1648-1652
    • Italian Cooperative Study Group on Chronic Myeloid Leukemia1
  • 134
    • 0029593313 scopus 로고
    • 5-Fluorouracil-resistant CD34+ cell population from peripheral blood of CML patients contains BCR-ABL-negative progenitor cells
    • B. Jazwiec F.X. Mahon A. Pigneux 5-Fluorouracil-resistant CD34+ cell population from peripheral blood of CML patients contains BCR-ABL-negative progenitor cells Exp Hematol 23 1995 1509 1514
    • (1995) Exp Hematol , vol.23 , pp. 1509-1514
    • Jazwiec, B.1    Mahon, F.X.2    Pigneux, A.3
  • 136
    • 0024990851 scopus 로고
    • Separation of pluripotent hematopoietic stem cells from spleen colony-forming cells
    • R.J. Jones J.E. Wagner P. Celano Separation of pluripotent hematopoietic stem cells from spleen colony-forming cells Nature 347 1990 188 190
    • (1990) Nature , vol.347 , pp. 188-190
    • Jones, R.J.1    Wagner, J.E.2    Celano, P.3
  • 137
    • 0029858031 scopus 로고    scopus 로고
    • Selectins and their ligands: Current concepts and controversies
    • G.S. Kansas Selectins and their ligands: Current concepts and controversies Blood 88 1996 3259 3287
    • (1996) Blood , vol.88 , pp. 3259-3287
    • Kansas, G.S.1
  • 138
    • 0022356841 scopus 로고
    • Chronic myelogenous leukemia: A multivariate analysis of the associations of patient characteristics and therapy with survival
    • H.M. Kantarjian T.L. Smith K.B. McCredie Chronic myelogenous leukemia: A multivariate analysis of the associations of patient characteristics and therapy with survival Blood 66 1985 1326
    • (1985) Blood , vol.66 , pp. 1326
    • Kantarjian, H.M.1    Smith, T.L.2    McCredie, K.B.3
  • 139
    • 0029872496 scopus 로고    scopus 로고
    • Decreased L-selectin expression in CD34-positive cells from patients with chronic myelocytic leukaemia
    • K. Kawaishi A. Kimura O. Katoh Decreased L-selectin expression in CD34-positive cells from patients with chronic myelocytic leukaemia Br J Haematol 93 1996 367 374
    • (1996) Br J Haematol , vol.93 , pp. 367-374
    • Kawaishi, K.1    Kimura, A.2    Katoh, O.3
  • 140
    • 15444349569 scopus 로고
    • α-interferon downregulates transcription of BCR-ABL in colonies arising from Ph+ early hematopoietic progenitors in patients with chronic myeloid leukemia
    • A. Keating B.A. Guinn P. Laraya X.H. Wang α-interferon downregulates transcription of BCR-ABL in colonies arising from Ph+ early hematopoietic progenitors in patients with chronic myeloid leukemia Blood 86 suppl 1 1995 2096a
    • (1995) Blood , vol.86 , Issue.suppl 1 , pp. 2096a
    • Keating, A.1    Guinn, B.A.2    Laraya, P.3    Wang, X.H.4
  • 141
    • 0028030701 scopus 로고
    • Distinct and overlapping direct effects of macrophage inflammatory protein-1 alpha and transforming growth factor beta on hematopoietic progenitor/stem cell growth
    • J.R. Keller S.H. Bartelmez E. Sitnicka Distinct and overlapping direct effects of macrophage inflammatory protein-1 alpha and transforming growth factor beta on hematopoietic progenitor/stem cell growth Blood 84 1994 2175 2181
    • (1994) Blood , vol.84 , pp. 2175-2181
    • Keller, J.R.1    Bartelmez, S.H.2    Sitnicka, E.3
  • 142
    • 0025159120 scopus 로고
    • Transforming growth factor β directly regulates primitive murine hematopoeitic cell proliferation
    • J.R. Keller I.K. McNiece K.T. Sill Transforming growth factor β directly regulates primitive murine hematopoeitic cell proliferation Blood 75 1990 596 602
    • (1990) Blood , vol.75 , pp. 596-602
    • Keller, J.R.1    McNiece, I.K.2    Sill, K.T.3
  • 143
    • 0027514616 scopus 로고
    • Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way
    • J.M. Kerst J.B. Sanders I.C. Slaper-Cortenbach Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way Blood 81 1993 344 351
    • (1993) Blood , vol.81 , pp. 344-351
    • Kerst, J.M.1    Sanders, J.B.2    Slaper-Cortenbach, I.C.3
  • 144
    • 0029043463 scopus 로고
    • Benign marrow progenitors are enriched in the CD34+/HLA-DRlo population but not in the CD34+/CD381o population in chronic myeloid leukemia: An analysis using interphase fluorescence in situ hybridization
    • J.A. Kirk J.A. Reems B.A. Roecklein Benign marrow progenitors are enriched in the CD34+/HLA-DRlo population but not in the CD34+/CD381o population in chronic myeloid leukemia: An analysis using interphase fluorescence in situ hybridization Blood 86 1995 737 743
    • (1995) Blood , vol.86 , pp. 737-743
    • Kirk, J.A.1    Reems, J.A.2    Roecklein, B.A.3
  • 145
    • 0026512171 scopus 로고
    • A monoclonal antibody to β1 integrin [CD29] stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components
    • N.L. Kovach T.M. Carlos E. Yee J.M. Harlan A monoclonal antibody to β1 integrin [CD29] stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components J Cell Biol 116 1992 499 509
    • (1992) J Cell Biol , vol.116 , pp. 499-509
    • Kovach, N.L.1    Carlos, T.M.2    Yee, E.3    Harlan, J.M.4
  • 146
    • 0021173673 scopus 로고
    • Chronic myelocytic leukemia: Ultrastructural histopathology of bone marrow from patients in the chronic phase
    • F. Kuto T. Nagaoka Y. Watanabe Chronic myelocytic leukemia: Ultrastructural histopathology of bone marrow from patients in the chronic phase Ultrastruct Pathol 6 1984 307 317
    • (1984) Ultrastruct Pathol , vol.6 , pp. 307-317
    • Kuto, F.1    Nagaoka, T.2    Watanabe, Y.3
  • 147
    • 0029348008 scopus 로고
    • Abl tyrosine protein kinase
    • P. Laneuville Abl tyrosine protein kinase Semin Immunol 7 1995 255
    • (1995) Semin Immunol , vol.7 , pp. 255
    • Laneuville, P.1
  • 148
    • 0027296746 scopus 로고
    • Ontogeny-related changes in proliferative potential of human hematopoietic cells
    • P.M. Lansdorp W. Dragowska H. Mayani Ontogeny-related changes in proliferative potential of human hematopoietic cells J Exp Med 178 1993 787
    • (1993) J Exp Med , vol.178 , pp. 787
    • Lansdorp, P.M.1    Dragowska, W.2    Mayani, H.3
  • 149
    • 0026505736 scopus 로고
    • Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow
    • P.M. Lansdorp W. Dragowska Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow J Exp Med 175 1992 1501 1509
    • (1992) J Exp Med , vol.175 , pp. 1501-1509
    • Lansdorp, P.M.1    Dragowska, W.2
  • 150
    • 0026581239 scopus 로고
    • Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
    • T. Lapidot F. Pflumio M. Doedens Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice Science 255 1992 1137 1141
    • (1992) Science , vol.255 , pp. 1137-1141
    • Lapidot, T.1    Pflumio, F.2    Doedens, M.3
  • 151
    • 0027988299 scopus 로고
    • Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells
    • D.I. Leavesley J.M. Oliver B.W. Swart Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells J Immunol 153 1994 4673 4683
    • (1994) J Immunol , vol.153 , pp. 4673-4683
    • Leavesley, D.I.1    Oliver, J.M.2    Swart, B.W.3
  • 152
    • 0027392819 scopus 로고
    • Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow
    • T. Leemhuis D. Leibowitz G. Cox Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow Blood 81 1993 801 807
    • (1993) Blood , vol.81 , pp. 801-807
    • Leemhuis, T.1    Leibowitz, D.2    Cox, G.3
  • 153
    • 0001645294 scopus 로고
    • Inhibitor of hematopoietic pluripotent stem cell proliferation: Purification and determination of its structure
    • M. Lenfant J. Wdzieczak-Bakala E. Guittet Inhibitor of hematopoietic pluripotent stem cell proliferation: Purification and determination of its structure Proc Natl Acad Sci USA 86 1989 779 782
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 779-782
    • Lenfant, M.1    Wdzieczak-Bakala, J.2    Guittet, E.3
  • 154
    • 0026537561 scopus 로고
    • Requirement for hyaluronic acid binding by CD44: A role for the cytoplasmic domain and activation by antibody
    • J. Lesley Q. He K. Miyake Requirement for hyaluronic acid binding by CD44: A role for the cytoplasmic domain and activation by antibody J Exp Med 175 1992 257 266
    • (1992) J Exp Med , vol.175 , pp. 257-266
    • Lesley, J.1    He, Q.2    Miyake, K.3
  • 155
    • 0027393054 scopus 로고
    • Expression of integrins and examination of their adhesive function in normal and leukemic hematopoietic cells
    • J.L. Liesveld J.M. Winslow K.E. Frediani Expression of integrins and examination of their adhesive function in normal and leukemic hematopoietic cells Blood 81 1993 112 121
    • (1993) Blood , vol.81 , pp. 112-121
    • Liesveld, J.L.1    Winslow, J.M.2    Frediani, K.E.3
  • 156
    • 0027324305 scopus 로고
    • Interleukin-3: Structure and function
    • A. Lindemann R. Mertelsmann Interleukin-3: Structure and function Cancer Invest 11 1993 609 623
    • (1993) Cancer Invest , vol.11 , pp. 609-623
    • Lindemann, A.1    Mertelsmann, R.2
  • 157
    • 0028020531 scopus 로고
    • Clinical implications of qualitative and quantitative polymerase chain reaction analysis in the monitoring of patients with chronic myelogenous leukemia. The European Investigators on Chronic Myeloid Leukemia Group
    • T. Lion Clinical implications of qualitative and quantitative polymerase chain reaction analysis in the monitoring of patients with chronic myelogenous leukemia. The European Investigators on Chronic Myeloid Leukemia Group Bone Marrow Transplant 14 1994 505 509
    • (1994) Bone Marrow Transplant , vol.14 , pp. 505-509
    • Lion, T.1
  • 158
    • 0025337660 scopus 로고
    • Thrombospondin functions as a cytoadhesion molecule for human hematopoietic progenitor cells
    • M.W. Long V.M. Dixit Thrombospondin functions as a cytoadhesion molecule for human hematopoietic progenitor cells Blood 75 1990 2311 2318
    • (1990) Blood , vol.75 , pp. 2311-2318
    • Long, M.W.1    Dixit, V.M.2
  • 159
    • 0027194631 scopus 로고
    • Macrophage inflammatory protein: Its characteristics, biological properties and role in the regulation of haemopoiesis
    • B.I. Lord C.M. Heyworth L.B. Woolford Macrophage inflammatory protein: Its characteristics, biological properties and role in the regulation of haemopoiesis Int J Hematol 57 1993 197
    • (1993) Int J Hematol , vol.57 , pp. 197
    • Lord, B.I.1    Heyworth, C.M.2    Woolford, L.B.3
  • 160
    • 85119460952 scopus 로고    scopus 로고
    • BI Lundell, JB McCarthy, NL Kovach, CM Verfaillie, Activation of β1-integrins on CML progenitors reveals cooperation between β1-integrins and CD44 in regulation of adhesion and proliferation. Leukemia, in press
  • 161
    • 0029665151 scopus 로고    scopus 로고
    • Adhesion to fibronectin (FN) induced by the activating anti-integrin-β1 antibody, 8a2, restores adhesion mediated inhibition of CML progenitor proliferation
    • B.I. Lundell J.B. McCarthy N.L. Kovach C.M. Verfaillie Adhesion to fibronectin (FN) induced by the activating anti-integrin-β1 antibody, 8a2, restores adhesion mediated inhibition of CML progenitor proliferation Blood 87 1996 2450 2458
    • (1996) Blood , vol.87 , pp. 2450-2458
    • Lundell, B.I.1    McCarthy, J.B.2    Kovach, N.L.3    Verfaillie, C.M.4
  • 162
    • 0029016931 scopus 로고
    • Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro
    • J. Maciejewski C. Selleri S. Anderson N.S. Young Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro Blood 85 1995 3183 3190
    • (1995) Blood , vol.85 , pp. 3183-3190
    • Maciejewski, J.1    Selleri, C.2    Anderson, S.3    Young, N.S.4
  • 163
    • 0029836465 scopus 로고    scopus 로고
    • BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia
    • V. Maguer-Satta A.L. Petzer A.C. Eaves C.J. Eaves BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia Blood 88 1996 1796 1804
    • (1996) Blood , vol.88 , pp. 1796-1804
    • Maguer-Satta, V.1    Petzer, A.L.2    Eaves, A.C.3    Eaves, C.J.4
  • 164
    • 0029871267 scopus 로고    scopus 로고
    • Kinetics of colony formation by BFU-E grown under different culture conditions in vitro
    • S.B. Marley T.A. Amos M.Y. Gordon Kinetics of colony formation by BFU-E grown under different culture conditions in vitro Br J Haematol 92 1996 559 561
    • (1996) Br J Haematol , vol.92 , pp. 559-561
    • Marley, S.B.1    Amos, T.A.2    Gordon, M.Y.3
  • 165
    • 0029941576 scopus 로고    scopus 로고
    • Abnormal kinetics of colony formation by erythroid burst-forming units (BFU-E) in chronic myeloid leukaemia
    • S.B. Marley J.L. Lewis J.M. Goldman M.Y. Gordon Abnormal kinetics of colony formation by erythroid burst-forming units (BFU-E) in chronic myeloid leukaemia Br J Haematol 93 1996 878 883
    • (1996) Br J Haematol , vol.93 , pp. 878-883
    • Marley, S.B.1    Lewis, J.L.2    Goldman, J.M.3    Gordon, M.Y.4
  • 166
    • 0025942490 scopus 로고
    • The BCR gene encodes a novel serine/threonine kinase activity within a single exon
    • Y. Maru O.N. Witte The BCR gene encodes a novel serine/threonine kinase activity within a single exon Cell 67 1991 459
    • (1991) Cell , vol.67 , pp. 459
    • Maru, Y.1    Witte, O.N.2
  • 167
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • J.M. McCune R. Namikawa H. Kaneshima The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function Science 241 1988 1632 1639
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3
  • 168
    • 0027979832 scopus 로고
    • BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
    • A. McGahon R. Bissonnette M. Schmitt BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death Blood 83 1994 1179
    • (1994) Blood , vol.83 , pp. 1179
    • McGahon, A.1    Bissonnette, R.2    Schmitt, M.3
  • 169
    • 0023178561 scopus 로고
    • Effect of recombinant gamma interferon on chronic myelogenous leukemia bone marrow progenitors
    • P. McGlave S. Mamus B. Vilen G. Dewald Effect of recombinant gamma interferon on chronic myelogenous leukemia bone marrow progenitors Exp Hematol 15 1987 331 335
    • (1987) Exp Hematol , vol.15 , pp. 331-335
    • McGlave, P.1    Mamus, S.2    Vilen, B.3    Dewald, G.4
  • 170
    • 0025287819 scopus 로고
    • Bone marrow transplants in chronic myelogenous leukemia: An overview of determinants of survival
    • P. McGlave Bone marrow transplants in chronic myelogenous leukemia: An overview of determinants of survival Semin Hematol 27 1990 23 30
    • (1990) Semin Hematol , vol.27 , pp. 23-30
    • McGlave, P.1
  • 171
    • 0027633614 scopus 로고
    • Unrelated donor and autologous marrow transplant therapy of chronic myelogenous leukemia
    • P. McGlave Unrelated donor and autologous marrow transplant therapy of chronic myelogenous leukemia Leukemia 7 1993 1092 1083
    • (1993) Leukemia , vol.7 , pp. 1092-1083
    • McGlave, P.1
  • 172
    • 0025004696 scopus 로고
    • Autologous transplantation for CML using marrow treated ex vivo with recombinant human interferon gamma
    • P.B. McGlave D. Arthur W.J. Miller Autologous transplantation for CML using marrow treated ex vivo with recombinant human interferon gamma Bone Marrow Transplant 6 1990 115 120
    • (1990) Bone Marrow Transplant , vol.6 , pp. 115-120
    • McGlave, P.B.1    Arthur, D.2    Miller, W.J.3
  • 173
    • 0028283040 scopus 로고
    • Autologous transplant therapy for chronic myelogenous leukemia prolongs survival: Results from eight transplant centers
    • P.B. McGlave P. DeFabritiis A. Deisseroth Autologous transplant therapy for chronic myelogenous leukemia prolongs survival: Results from eight transplant centers Lancet 343 1994 1486 1488
    • (1994) Lancet , vol.343 , pp. 1486-1488
    • McGlave, P.B.1    DeFabritiis, P.2    Deisseroth, A.3
  • 175
    • 0027422977 scopus 로고
    • A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins
    • J.R. McWhirter D.L. Galasso J.Y. Wang A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins Mol Cell Biol 13 1993 7587
    • (1993) Mol Cell Biol , vol.13 , pp. 7587
    • McWhirter, J.R.1    Galasso, D.L.2    Wang, J.Y.3
  • 176
    • 0025924674 scopus 로고
    • Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins
    • J.R. McWhirter J.Y. Wang Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins Mol Cell Biol 11 1991 1553
    • (1991) Mol Cell Biol , vol.11 , pp. 1553
    • McWhirter, J.R.1    Wang, J.Y.2
  • 177
    • 0027536793 scopus 로고
    • An actin-binding function contributes to transformation by the BCR-ABL oncoprotein in Philadelphia chromosome positive human leukemias
    • J.R. McWhirter J.Y. Wang An actin-binding function contributes to transformation by the BCR-ABL oncoprotein in Philadelphia chromosome positive human leukemias EMBO J 12 1993 1533 1546
    • (1993) EMBO J , vol.12 , pp. 1533-1546
    • McWhirter, J.R.1    Wang, J.Y.2
  • 178
    • 0027519167 scopus 로고
    • The ABL-BCR fusion gene is expressed in chronic myeloid leukemia
    • J.V. Melo D.E. Gordon N.C. Cross The ABL-BCR fusion gene is expressed in chronic myeloid leukemia Blood 81 1993 158
    • (1993) Blood , vol.81 , pp. 158
    • Melo, J.V.1    Gordon, D.E.2    Cross, N.C.3
  • 179
    • 0029816460 scopus 로고    scopus 로고
    • The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
    • J.V. Melo The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype Blood 88 1996 2375
    • (1996) Blood , vol.88 , pp. 2375
    • Melo, J.V.1
  • 180
    • 0030026693 scopus 로고    scopus 로고
    • Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor
    • C. Minshall S. Arkins G.G. Freund Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor J Immunol 156 1996 939
    • (1996) J Immunol , vol.156 , pp. 939
    • Minshall, C.1    Arkins, S.2    Freund, G.G.3
  • 181
    • 0025137103 scopus 로고
    • Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures
    • K. Miyake K.L. Medina Hayashi S.-I. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures J Exp Med 171 1990 477 488
    • (1990) J Exp Med , vol.171 , pp. 477-488
    • Miyake, K.1    Medina, K.L.2    Hayashi, S.-I.3
  • 182
    • 0028801218 scopus 로고
    • Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules
    • S. Miyamoto H. Teramoto O.A. Coso Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules J Cell Bio 1995 791 805
    • (1995) J Cell Bio , pp. 791-805
    • Miyamoto, S.1    Teramoto, H.2    Coso, O.A.3
  • 183
    • 0029561654 scopus 로고
    • Differential expression of L-selectin, VLA-4, and LFA-1 on CD34+ progenitor cells from bone marrow and peripheral blood during G-CSF–enhanced recovery
    • R. Mohle S. Murea M. Kirsch R. Haas Differential expression of L-selectin, VLA-4, and LFA-1 on CD34+ progenitor cells from bone marrow and peripheral blood during G-CSF–enhanced recovery Exp Hematol 23 1995 1535
    • (1995) Exp Hematol , vol.23 , pp. 1535
    • Mohle, R.1    Murea, S.2    Kirsch, M.3    Haas, R.4
  • 184
    • 0027504708 scopus 로고
    • Autografting for patients with chronic myeloid leukemia—the Hammersmith experience
    • T. Mughal C. Hoyle J.M. Goldman Autografting for patients with chronic myeloid leukemia—the Hammersmith experience Stem Cells 11 suppl 3 1993 20 22
    • (1993) Stem Cells , vol.11 , Issue.suppl 3 , pp. 20-22
    • Mughal, T.1    Hoyle, C.2    Goldman, J.M.3
  • 185
    • 0025959660 scopus 로고
    • BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene in Philadelphia chromosome positive leukemias
    • A.J. Muller J.C. Young A.M. Pendergast BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene in Philadelphia chromosome positive leukemias Mol Cell Biol 11 1991 1785
    • (1991) Mol Cell Biol , vol.11 , pp. 1785
    • Muller, A.J.1    Young, J.C.2    Pendergast, A.M.3
  • 186
    • 0029088689 scopus 로고
    • Differential effects of TGF-beta 1 on normal and leukemic human hematopoietic cell proliferation
    • I. Murohashi K. Endho S. Nishida Differential effects of TGF-beta 1 on normal and leukemic human hematopoietic cell proliferation Exp Hematol 23 1995 970 977
    • (1995) Exp Hematol , vol.23 , pp. 970-977
    • Murohashi, I.1    Endho, K.2    Nishida, S.3
  • 187
    • 0028890278 scopus 로고
    • Expression of c-kit receptor (CD117) and CD34 in leukemic cells
    • K. Muroi M. Nakamura Y. Amemiya Expression of c-kit receptor (CD117) and CD34 in leukemic cells Leuk Lymphoma 16 1995 297 305
    • (1995) Leuk Lymphoma , vol.16 , pp. 297-305
    • Muroi, K.1    Nakamura, M.2    Amemiya, Y.3
  • 188
    • 0029159785 scopus 로고
    • Novel functions of phosphatidylinositol 3-kinase in terminally differentiated cells
    • S. Nakanishi H. Yano Y. Matsuda Novel functions of phosphatidylinositol 3-kinase in terminally differentiated cells Cell Signaling 7 1995 545 557
    • (1995) Cell Signaling , vol.7 , pp. 545-557
    • Nakanishi, S.1    Yano, H.2    Matsuda, Y.3
  • 189
    • 0026608509 scopus 로고
    • Diagnostic and clinical importance of interleukin-2 receptor alpha chain expression on non-T-cell acute leukaemia cells
    • K. Nakase K. Kita A. Otsuji Diagnostic and clinical importance of interleukin-2 receptor alpha chain expression on non-T-cell acute leukaemia cells Br J Haematol 80 1992 317 326
    • (1992) Br J Haematol , vol.80 , pp. 317-326
    • Nakase, K.1    Kita, K.2    Otsuji, A.3
  • 190
    • 0028849992 scopus 로고
    • c-kit point mutation of extracellular domain in patients with myeloproliferative disorders
    • Y. Nakata A. Kimura O. Katoh c-kit point mutation of extracellular domain in patients with myeloproliferative disorders Br J Haematol 91 1995 661 663
    • (1995) Br J Haematol , vol.91 , pp. 661-663
    • Nakata, Y.1    Kimura, A.2    Katoh, O.3
  • 191
    • 9244249776 scopus 로고    scopus 로고
    • Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation
    • N. Nelson Y. Kanno C. Hong Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation J Immunol 156 1996 3711 3720
    • (1996) J Immunol , vol.156 , pp. 3711-3720
    • Nelson, N.1    Kanno, Y.2    Hong, C.3
  • 192
    • 0027464265 scopus 로고
    • Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription
    • N. Nelson M.S. Marks P.H. Driggers K. Ozato Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription Mol Cell Biol 13 1993 588 599
    • (1993) Mol Cell Biol , vol.13 , pp. 588-599
    • Nelson, N.1    Marks, M.S.2    Driggers, P.H.3    Ozato, K.4
  • 193
    • 0029006231 scopus 로고
    • Interferon-alpha directly inhibits DNA polymerase activity in isolated chromatin nucleoprotein complexes: Correlation with IFN-alpha treatment outcome in patients with chronic myelogenous leukemia
    • N.L. Nicolson M. Talpaz G.L. Nicolson Interferon-alpha directly inhibits DNA polymerase activity in isolated chromatin nucleoprotein complexes: Correlation with IFN-alpha treatment outcome in patients with chronic myelogenous leukemia Gene 159 1995 105 111
    • (1995) Gene , vol.159 , pp. 105-111
    • Nicolson, N.L.1    Talpaz, M.2    Nicolson, G.L.3
  • 194
    • 0029004234 scopus 로고
    • Progenitor cells in the blood and marrow of patients with chronic phase chronic myeloid leukaemia respond differently to macrophage inflammatory protein-1 alpha
    • N. Nirsimloo M.Y. Gordon Progenitor cells in the blood and marrow of patients with chronic phase chronic myeloid leukaemia respond differently to macrophage inflammatory protein-1 alpha Leuk Res 19 1995 319 323
    • (1995) Leuk Res , vol.19 , pp. 319-323
    • Nirsimloo, N.1    Gordon, M.Y.2
  • 195
    • 0028325345 scopus 로고
    • Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: Analysis of gene transduction of long-lived progenitors
    • J.A. Nolta M.B. Hanley D.B. Kohn Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: Analysis of gene transduction of long-lived progenitors Blood 83 1994 3041 3051
    • (1994) Blood , vol.83 , pp. 3041-3051
    • Nolta, J.A.1    Hanley, M.B.2    Kohn, D.B.3
  • 196
    • 0000286732 scopus 로고
    • A minute chromosome in human chronic granulocytic leukemia
    • P.C. Nowell D.A. Hungerford A minute chromosome in human chronic granulocytic leukemia Science 132 1960 1497
    • (1960) Science , vol.132 , pp. 1497
    • Nowell, P.C.1    Hungerford, D.A.2
  • 197
    • 0023790229 scopus 로고
    • Lack of breakpoint cluster region rearrangement in marrow fibroblasts of patients with Philadelphia chromosome–positive chronic myelogenous leukemia
    • S. O'Brien H. Kantarjian M. Shtalrid Lack of breakpoint cluster region rearrangement in marrow fibroblasts of patients with Philadelphia chromosome–positive chronic myelogenous leukemia Hematol Pathol 2 1988 25 29
    • (1988) Hematol Pathol , vol.2 , pp. 25-29
    • O'Brien, S.1    Kantarjian, H.2    Shtalrid, M.3
  • 198
    • 0028142490 scopus 로고
    • Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia
    • T. Oda C. Heaney J.R. Hagopian Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia J Biol Chem 269 1994 22925
    • (1994) J Biol Chem , vol.269 , pp. 22925
    • Oda, T.1    Heaney, C.2    Hagopian, J.R.3
  • 199
    • 0030029752 scopus 로고    scopus 로고
    • Adhesion of human hematopoietic progenitor cells to bone-marrow–derived stromal cells is enhanced by antibodies to CD44
    • R.A. Oostendorp E. Spitzer P. Dormer Adhesion of human hematopoietic progenitor cells to bone-marrow–derived stromal cells is enhanced by antibodies to CD44 Acta Haematol 95 1996 243 247
    • (1996) Acta Haematol , vol.95 , pp. 243-247
    • Oostendorp, R.A.1    Spitzer, E.2    Dormer, P.3
  • 200
    • 0025945839 scopus 로고
    • Lack of evidence for abnormal autocrine or paracrine mechanisms underlying the uncontrolled proliferation of primitive chronic myeloid leukemia progenitor cells
    • T. Otsuka C.J. Eaves R.K. Humphries Lack of evidence for abnormal autocrine or paracrine mechanisms underlying the uncontrolled proliferation of primitive chronic myeloid leukemia progenitor cells Leukemia 5 1991 861 868
    • (1991) Leukemia , vol.5 , pp. 861-868
    • Otsuka, T.1    Eaves, C.J.2    Humphries, R.K.3
  • 201
    • 0028863504 scopus 로고
    • Guanine nucleotide exchange factors: Activators of Ras superfamily proteins
    • A.F. Overbeck T.R. Brtva A.D. Cox Guanine nucleotide exchange factors: Activators of Ras superfamily proteins Mol Reprod Dev 42 1995 468
    • (1995) Mol Reprod Dev , vol.42 , pp. 468
    • Overbeck, A.F.1    Brtva, T.R.2    Cox, A.D.3
  • 202
    • 0028971211 scopus 로고
    • The VLA4/VCAM adhesion pathway defines contrasting mechanisms of lodging of transplanted murine hematopoietic progenitors between bone marrow and spleen
    • T. Papayannopoulou C. Craddock B. Nakamoto The VLA4/VCAM adhesion pathway defines contrasting mechanisms of lodging of transplanted murine hematopoietic progenitors between bone marrow and spleen Proc Natl Acad Sci USA 92 1995 9647 9651
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9647-9651
    • Papayannopoulou, T.1    Craddock, C.2    Nakamoto, B.3
  • 203
    • 0027484275 scopus 로고
    • Systemic treatment of primates with anti-VLA4 leads to an immediate egress of hemopoietic progenitors to periphery
    • T. Papayannopoulou B. Nakamato Systemic treatment of primates with anti-VLA4 leads to an immediate egress of hemopoietic progenitors to periphery Proc Natl Acad Sci USA 90 1993 9374 9378
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9374-9378
    • Papayannopoulou, T.1    Nakamato, B.2
  • 204
    • 0023546121 scopus 로고
    • Erythroleukemia cells into reticulocytes
    • V.P. Patel H.F. Lodish Erythroleukemia cells into reticulocytes J Cell Biol 105 1987 3105 3118
    • (1987) J Cell Biol , vol.105 , pp. 3105-3118
    • Patel, V.P.1    Lodish, H.F.2
  • 205
    • 0025058366 scopus 로고
    • Prevention of hematotoxic side effects of cytostatic drugs in mice by a synthetic hemoregulatory peptide
    • W.R. Paukovits M. Guigon K.A. Binder Prevention of hematotoxic side effects of cytostatic drugs in mice by a synthetic hemoregulatory peptide Cancer Res 50 1990 328 332
    • (1990) Cancer Res , vol.50 , pp. 328-332
    • Paukovits, W.R.1    Guigon, M.2    Binder, K.A.3
  • 206
    • 0027511824 scopus 로고
    • SH1 domain autophosphorylation of p210 BCR-ABL is required for transformation but not growth factor independence
    • A.M. Pendergast M.L. Gishizky M.H. Havlik O.N. Witte SH1 domain autophosphorylation of p210 BCR-ABL is required for transformation but not growth factor independence Mol Cell Biol 13 1993 1728 1732
    • (1993) Mol Cell Biol , vol.13 , pp. 1728-1732
    • Pendergast, A.M.1    Gishizky, M.L.2    Havlik, M.H.3    Witte, O.N.4
  • 207
    • 0027368352 scopus 로고
    • BCR-ABL–induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein
    • A.M. Pendergast L.A. Quilliam L.D. Cripe BCR-ABL–induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein Cell 75 1993 175 185
    • (1993) Cell , vol.75 , pp. 175-185
    • Pendergast, A.M.1    Quilliam, L.A.2    Cripe, L.D.3
  • 208
    • 0025766195 scopus 로고
    • BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner
    • A.M. Pendergast A.J. Muller M.H. Havlik BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner Cell 66 1991 161 171
    • (1991) Cell , vol.66 , pp. 161-171
    • Pendergast, A.M.1    Muller, A.J.2    Havlik, M.H.3
  • 209
    • 0029837399 scopus 로고    scopus 로고
    • Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia
    • A.L. Petzer C.J. Eaves P.M. Lansdorp Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia Blood 88 1996 2162 2171
    • (1996) Blood , vol.88 , pp. 2162-2171
    • Petzer, A.L.1    Eaves, C.J.2    Lansdorp, P.M.3
  • 210
    • 0028817908 scopus 로고
    • Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex
    • G.E. Plopper H.P. McNamee L.E. Dike Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex Mol Biol Cell 6 1995 1349 1365
    • (1995) Mol Biol Cell , vol.6 , pp. 1349-1365
    • Plopper, G.E.1    McNamee, H.P.2    Dike, L.E.3
  • 211
    • 0029815705 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of long-term culture initiating cells (LTC-IC) present in peripheral blood progenitor collections of normal donors treated with G-CSF
    • F. Prosper D. Stronceck C.M. Verfaillie Phenotypic and functional characterization of long-term culture initiating cells (LTC-IC) present in peripheral blood progenitor collections of normal donors treated with G-CSF Blood 88 1996 2033 2042
    • (1996) Blood , vol.88 , pp. 2033-2042
    • Prosper, F.1    Stronceck, D.2    Verfaillie, C.M.3
  • 212
    • 0031005520 scopus 로고    scopus 로고
    • Expansion of primitive LTC-IC from G-CSF mobilized peripheral blood progenitor cells (PBPC)
    • F. Prosper D. Stroncek C.M. Verfaillie Expansion of primitive LTC-IC from G-CSF mobilized peripheral blood progenitor cells (PBPC) Blood 89 1997 3991 3997
    • (1997) Blood , vol.89 , pp. 3991-3997
    • Prosper, F.1    Stroncek, D.2    Verfaillie, C.M.3
  • 213
    • 0027450064 scopus 로고
    • Use of 5-fluorouracil to analyze the effect of macrophage inflammatory protein-1 alpha on long-term reconstituting stem cells in vivo
    • V.F. Quesniaux G.J. Graham I. Pragnell Use of 5-fluorouracil to analyze the effect of macrophage inflammatory protein-1 alpha on long-term reconstituting stem cells in vivo Blood 81 1993 1497 1504
    • (1993) Blood , vol.81 , pp. 1497-1504
    • Quesniaux, V.F.1    Graham, G.J.2    Pragnell, I.3
  • 215
    • 0028972616 scopus 로고
    • Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance
    • J.C. Reed Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance Curr Opin Oncol 7 1995 541
    • (1995) Curr Opin Oncol , vol.7 , pp. 541
    • Reed, J.C.1
  • 216
    • 0028110855 scopus 로고
    • Autologous stem cell transplantation in chronic myelogenous leukemia: A retrospective analysis of the European Group for Bone Marrow Transplantation. Chronic Leukemia Working Party of the EBMT
    • J. Reiffers J. Goldman G. Meloni Autologous stem cell transplantation in chronic myelogenous leukemia: A retrospective analysis of the European Group for Bone Marrow Transplantation. Chronic Leukemia Working Party of the EBMT Bone Marrow Transplant 14 1994 407
    • (1994) Bone Marrow Transplant , vol.14 , pp. 407
    • Reiffers, J.1    Goldman, J.2    Meloni, G.3
  • 217
    • 0028881598 scopus 로고
    • The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation
    • M.W. Renshaw J.R. McWhirter J.Y. Wang The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation Mol Cell Biol 15 1995 1286 1293
    • (1995) Mol Cell Biol , vol.15 , pp. 1286-1293
    • Renshaw, M.W.1    McWhirter, J.R.2    Wang, J.Y.3
  • 218
    • 0028127003 scopus 로고
    • Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family
    • G.W. Reuther H. Fu L.D. Cripe Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family Science. 266 1994 129
    • (1994) Science. , vol.266 , pp. 129
    • Reuther, G.W.1    Fu, H.2    Cripe, L.D.3
  • 219
    • 0028263529 scopus 로고
    • Direct demonstration that autologous marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells
    • D.R. Rill M. Santana M. Roberts Direct demonstration that autologous marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells Blood 84 1994 380 383
    • (1994) Blood , vol.84 , pp. 380-383
    • Rill, D.R.1    Santana, M.2    Roberts, M.3
  • 220
    • 0028692469 scopus 로고
    • Use of CD33 monoclonal antibodies in bone marrow transplantation for acute myeloid leukemia
    • M.J. Robertson D.C. Roy R.M. Stone J. Ritz Use of CD33 monoclonal antibodies in bone marrow transplantation for acute myeloid leukemia Prog Clin Biol Res 389 1994 47 63
    • (1994) Prog Clin Biol Res , vol.389 , pp. 47-63
    • Robertson, M.J.1    Roy, D.C.2    Stone, R.M.3    Ritz, J.4
  • 222
    • 0029989289 scopus 로고    scopus 로고
    • An antibody to CD44 enhances hematopoiesis in long-term marrow cultures
    • H.C. Rossbach L. Krizanac-Bengez E.B. Santos An antibody to CD44 enhances hematopoiesis in long-term marrow cultures Exp Hematol 24 1996 221 227
    • (1996) Exp Hematol , vol.24 , pp. 221-227
    • Rossbach, H.C.1    Krizanac-Bengez, L.2    Santos, E.B.3
  • 223
    • 0001313041 scopus 로고
    • A new consistent chromosome abnormality in chronic myelogenous leukemia
    • J.D. Rowley A new consistent chromosome abnormality in chronic myelogenous leukemia Nature 243 1973 209 291
    • (1973) Nature , vol.243 , pp. 209-291
    • Rowley, J.D.1
  • 224
    • 85119462894 scopus 로고    scopus 로고
    • Adult marrow, cord blood and fetal liver progenitors differ in their adhesive properties and expression of cell adhesion molecules
    • V. Roy C.M. Verfaillie Adult marrow, cord blood and fetal liver progenitors differ in their adhesive properties and expression of cell adhesion molecules Blood 88 1996 2133a
    • (1996) Blood , vol.88 , pp. 2133a
    • Roy, V.1    Verfaillie, C.M.2
  • 225
    • 0027213710 scopus 로고
    • Pleiotropic effects of transforming growth factor–beta on cells of the immune system
    • F. Ruscetti L. Varesio A. Ochoa J. Ortaldo Pleiotropic effects of transforming growth factor–beta on cells of the immune system Ann NY Acad Sci 685 1993 488 500
    • (1993) Ann NY Acad Sci , vol.685 , pp. 488-500
    • Ruscetti, F.1    Varesio, L.2    Ochoa, A.3    Ortaldo, J.4
  • 226
    • 0027948205 scopus 로고
    • Induction of apoptosis by a dominant negative H-RAS mutant (116Y) in K562 cells
    • N. Sakai Y. Ogiso H. Fujita Induction of apoptosis by a dominant negative H-RAS mutant (116Y) in K562 cells Exp Cell Res 215 1994 131
    • (1994) Exp Cell Res , vol.215 , pp. 131
    • Sakai, N.1    Ogiso, Y.2    Fujita, H.3
  • 227
    • 0028875460 scopus 로고
    • Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR-ABL
    • R. Salgia B. Brunkhorst E. Pisick Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR-ABL Oncogene 11 1995 1149
    • (1995) Oncogene , vol.11 , pp. 1149
    • Salgia, R.1    Brunkhorst, B.2    Pisick, E.3
  • 228
    • 0028925737 scopus 로고
    • Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR-ABL
    • R. Salgia J.L. Li S.H. Lo Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR-ABL J Biol Chem 270 1995 5039
    • (1995) J Biol Chem , vol.270 , pp. 5039
    • Salgia, R.1    Li, J.L.2    Lo, S.H.3
  • 229
    • 85058206865 scopus 로고    scopus 로고
    • Transformation of hematopoietic cells by BCR-ABL is associated with enhanced motility
    • R. Salgia J.R. Li E. Curry Transformation of hematopoietic cells by BCR-ABL is associated with enhanced motility Blood 88 1996 2684a
    • (1996) Blood , vol.88 , pp. 2684a
    • Salgia, R.1    Li, J.R.2    Curry, E.3
  • 230
    • 0029664864 scopus 로고    scopus 로고
    • p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl
    • R. Salgia M. Sattler E. Pisick p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl Exp Hematol 24 1996 31
    • (1996) Exp Hematol , vol.24 , pp. 31
    • Salgia, R.1    Sattler, M.2    Pisick, E.3
  • 231
    • 0029015690 scopus 로고
    • Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2
    • I. Sanchez-Garcia G. Grutz Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2 Proc Natl Acad Sci USA 92 1995 5287
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5287
    • Sanchez-Garcia, I.1    Grutz, G.2
  • 232
    • 0029669975 scopus 로고    scopus 로고
    • The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3′ kinase pathway
    • M. Sattler R. Salgia K. Okuda The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3′ kinase pathway Oncogene 12 1996 839
    • (1996) Oncogene , vol.12 , pp. 839
    • Sattler, M.1    Salgia, R.2    Okuda, K.3
  • 233
    • 0026788001 scopus 로고
    • Dominant negative MYC blocks transformation by ABL oncogenes
    • C.L. Sawyers W. Callahan O.N. Witte Dominant negative MYC blocks transformation by ABL oncogenes Cell 70 1992 901
    • (1992) Cell , vol.70 , pp. 901
    • Sawyers, C.L.1    Callahan, W.2    Witte, O.N.3
  • 234
    • 0028950123 scopus 로고
    • Genetic requirement for RAS in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene
    • C.L. Sawyers J. McLaughlin O.N. Witte Genetic requirement for RAS in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene J Exp Med 181 1995 307
    • (1995) J Exp Med , vol.181 , pp. 307
    • Sawyers, C.L.1    McLaughlin, J.2    Witte, O.N.3
  • 235
    • 0027723357 scopus 로고
    • Molecular consequences of the BCR-ABL translocation in chronic myelogenous leukemia
    • C.L. Sawyers Molecular consequences of the BCR-ABL translocation in chronic myelogenous leukemia Leuk Lymphoma 11 suppl 2 1993 101 103
    • (1993) Leuk Lymphoma , vol.11 , Issue.suppl 2 , pp. 101-103
    • Sawyers, C.L.1
  • 236
    • 0028263656 scopus 로고
    • B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein
    • T.M. Saxton van Oostveen I. D. Bowtell B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein J Immunol 153 1994 623
    • (1994) J Immunol , vol.153 , pp. 623
    • Saxton, T.M.1    van Oostveen, I.2    Bowtell, D.3
  • 237
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • M.D. Schaller J.T. Parsons Focal adhesion kinase and associated proteins Curr Opin Cell Biol 6 1994 705 710
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 238
    • 0028986116 scopus 로고
    • pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
    • M.D. Schaller J.T. Parsons pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk Mol Cell Biol 15 1995 2635
    • (1995) Mol Cell Biol , vol.15 , pp. 2635
    • Schaller, M.D.1    Parsons, J.T.2
  • 239
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • C. Schindler Darnell J.E. Jr Transcriptional responses to polypeptide ligands: The JAK-STAT pathway Annu Rev Biochem 64 1995 621
    • (1995) Annu Rev Biochem , vol.64 , pp. 621
    • Schindler, C.1    Darnell, J.E.2
  • 240
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    • D.D. Schlaepfer S.K. Hanks T. Hunter Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase Nature 372 1994 786
    • (1994) Nature , vol.372 , pp. 786
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3
  • 242
    • 0029990271 scopus 로고    scopus 로고
    • Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition
    • C. Selleri J.P. Maciejewski T. Sato N.S. Young Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition Blood 87 1996 4149 4157
    • (1996) Blood , vol.87 , pp. 4149-4157
    • Selleri, C.1    Maciejewski, J.P.2    Sato, T.3    Young, N.S.4
  • 243
    • 0029416957 scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death
    • C. Selleri T. Sato S. Anderson Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death J Cell Physiol 165 1995 538 546
    • (1995) J Cell Physiol , vol.165 , pp. 538-546
    • Selleri, C.1    Sato, T.2    Anderson, S.3
  • 244
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the hematopoietic stem cell: A hypothesis
    • R. Shofield The relationship between the spleen colony-forming cell and the hematopoietic stem cell: A hypothesis Blood Cells 4 1978 7 25
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Shofield, R.1
  • 245
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
    • K. Shuai J. Halpern ten Hoeve J. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia Oncogene 13 1996 247
    • (1996) Oncogene , vol.13 , pp. 247
    • Shuai, K.1    Halpern, J.2    ten Hoeve, J.3
  • 246
    • 0026770087 scopus 로고
    • Binding of primitive hematopoietic progenitor cells to marrow stromal cells involves heparan sulfate
    • M. Siczkowski D. Clarke M.Y. Gordon Binding of primitive hematopoietic progenitor cells to marrow stromal cells involves heparan sulfate Blood 80 1992 912 919
    • (1992) Blood , vol.80 , pp. 912-919
    • Siczkowski, M.1    Clarke, D.2    Gordon, M.Y.3
  • 247
    • 0028281042 scopus 로고
    • Expression of the c-kit proto-oncogene in myeloproliferative disorders and myelodysplastic syndromes
    • T. Siitonen E.R. Savolainen P. Koistinen Expression of the c-kit proto-oncogene in myeloproliferative disorders and myelodysplastic syndromes Leukemia 8 1994 631 637
    • (1994) Leukemia , vol.8 , pp. 631-637
    • Siitonen, T.1    Savolainen, E.R.2    Koistinen, P.3
  • 248
    • 0026688896 scopus 로고
    • Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells
    • P.J. Simmons B. Masinovsky B.M. Longenecker Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells Blood 80 1992 388
    • (1992) Blood , vol.80 , pp. 388
    • Simmons, P.J.1    Masinovsky, B.2    Longenecker, B.M.3
  • 249
    • 13344262695 scopus 로고    scopus 로고
    • Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis
    • C. Sirard T. Lapidot J. Vormoor Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis Blood 87 1996 1539
    • (1996) Blood , vol.87 , pp. 1539
    • Sirard, C.1    Lapidot, T.2    Vormoor, J.3
  • 250
    • 0028274049 scopus 로고
    • Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism
    • C. Sirard P. Laneuville J.E. Dick Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism Blood 83 1994 1575 1585
    • (1994) Blood , vol.83 , pp. 1575-1585
    • Sirard, C.1    Laneuville, P.2    Dick, J.E.3
  • 251
    • 0029948374 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells
    • E. Sitnicka F.W. Ruscetti G.V. Priestley Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells Blood 88 1996 82 88
    • (1996) Blood , vol.88 , pp. 82-88
    • Sitnicka, E.1    Ruscetti, F.W.2    Priestley, G.V.3
  • 252
    • 85119465943 scopus 로고    scopus 로고
    • An intact SH3 domain is required for BCR/ABL leukemogenisis: Role in adhesion, invasion and homing
    • T. Skorski M. Nieborowska-Skorska P. Wlodarski An intact SH3 domain is required for BCR/ABL leukemogenisis: Role in adhesion, invasion and homing Blood 88 1996 795a
    • (1996) Blood , vol.88 , pp. 795a
    • Skorski, T.1    Nieborowska-Skorska, M.2    Wlodarski, P.3
  • 253
    • 0029063970 scopus 로고
    • Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome–positive cells
    • T. Skorski P. Kanakaraj M. Nieborowska-Skorska Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome–positive cells Blood 86 1995 726
    • (1995) Blood , vol.86 , pp. 726
    • Skorski, T.1    Kanakaraj, P.2    Nieborowska-Skorska, M.3
  • 254
    • 0028115911 scopus 로고
    • Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome–positive cell line BV173
    • T.F.C.M. Smetsers T. Skorski van de Locht L.T.F. Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome–positive cell line BV173 Leukemia 8 1994 129
    • (1994) Leukemia , vol.8 , pp. 129
    • Smetsers, T.F.C.M.1    Skorski, T.2    van de Locht, L.T.F.3
  • 255
    • 0028908916 scopus 로고
    • Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells: In vivo expansion of stem cell phenotype but not function
    • G.J. Spangrude D.M. Brooks D.B. Tumas Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells: In vivo expansion of stem cell phenotype but not function Blood 85 1995 1006 1016
    • (1995) Blood , vol.85 , pp. 1006-1016
    • Spangrude, G.J.1    Brooks, D.M.2    Tumas, D.B.3
  • 256
    • 0027368564 scopus 로고
    • Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep
    • E.F. Srour E.D. Zanjani K. Cornetta Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep Blood 82 1993 3333 3342
    • (1993) Blood , vol.82 , pp. 3333-3342
    • Srour, E.F.1    Zanjani, E.D.2    Cornetta, K.3
  • 257
    • 0023675064 scopus 로고
    • Biology of chronic myelogenous leukemia: Is discordant maturation the primary defect?
    • A. Strife B. Clarkson Biology of chronic myelogenous leukemia: Is discordant maturation the primary defect? Semin Hematol 25 1988 1 19
    • (1988) Semin Hematol , vol.25 , pp. 1-19
    • Strife, A.1    Clarkson, B.2
  • 258
    • 0020510241 scopus 로고
    • Proliferative potential of subpopulations of granulocyte-macrophage progenitor cells in normal subjects and chronic myelogenous leukemia patients
    • A. Strife C. Lambek D. Wisniewski Proliferative potential of subpopulations of granulocyte-macrophage progenitor cells in normal subjects and chronic myelogenous leukemia patients Blood 62 1983 389 397
    • (1983) Blood , vol.62 , pp. 389-397
    • Strife, A.1    Lambek, C.2    Wisniewski, D.3
  • 259
    • 0023901483 scopus 로고
    • Discordant maturation as the primary biological defect in chronic myelogenous leukemia
    • A. Strife C. Lambek D. Wisniewski Discordant maturation as the primary biological defect in chronic myelogenous leukemia Cancer Res 48 1988 1035 1041
    • (1988) Cancer Res , vol.48 , pp. 1035-1041
    • Strife, A.1    Lambek, C.2    Wisniewski, D.3
  • 260
    • 0027430113 scopus 로고
    • Differences in the composition and in the efficiency of red cell production of normal and CML erythroid progenitor populations are highlighted by response to human c-kit ligand
    • A. Strife A. Perez C. Lambek Differences in the composition and in the efficiency of red cell production of normal and CML erythroid progenitor populations are highlighted by response to human c-kit ligand Leuk Res 17 1993 799 807
    • (1993) Leuk Res , vol.17 , pp. 799-807
    • Strife, A.1    Perez, A.2    Lambek, C.3
  • 261
    • 0024466796 scopus 로고
    • Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro
    • H.J. Sutherland C.J. Eaves A.C. Eaves Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro Blood 74 1989 1563 1570
    • (1989) Blood , vol.74 , pp. 1563-1570
    • Sutherland, H.J.1    Eaves, C.J.2    Eaves, A.C.3
  • 262
    • 0025739613 scopus 로고
    • Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells
    • H.J. Sutherland C.J. Eaves P.M. Lansdorp Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells Blood 78 1991 666 672
    • (1991) Blood , vol.78 , pp. 666-672
    • Sutherland, H.J.1    Eaves, C.J.2    Lansdorp, P.M.3
  • 263
    • 0027466339 scopus 로고
    • Alternative mechanisms with and without steel factor support primitive human hematopoiesis
    • H.J. Sutherland D.E. Hogge D. Cook C.J. Eaves Alternative mechanisms with and without steel factor support primitive human hematopoiesis Blood 81 1993 1465 1470
    • (1993) Blood , vol.81 , pp. 1465-1470
    • Sutherland, H.J.1    Hogge, D.E.2    Cook, D.3    Eaves, C.J.4
  • 264
    • 0025297090 scopus 로고
    • Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers
    • H.J. Sutherland P.M. Lansdorp D.H. Henkelman Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers Proc Natl Acad Sci USA 87 1990 3584 3588
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3584-3588
    • Sutherland, H.J.1    Lansdorp, P.M.2    Henkelman, D.H.3
  • 265
    • 0022408205 scopus 로고
    • A functional defect in irradiated adherent layers from chronic myelogenous leukemia long-term marrow cultures
    • M. Takahashi A. Keating J.W. Singer A functional defect in irradiated adherent layers from chronic myelogenous leukemia long-term marrow cultures Exp Hematol 13 1985 926 931
    • (1985) Exp Hematol , vol.13 , pp. 926-931
    • Takahashi, M.1    Keating, A.2    Singer, J.W.3
  • 266
    • 0024609840 scopus 로고
    • Appearance of chromosomally normal hemopoiesis during busulfan-induced remission in a case of Ph1 positive chronic myelogenous leukemia
    • H. Takahira H. Ideguchi J. Hirata Appearance of chromosomally normal hemopoiesis during busulfan-induced remission in a case of Ph1 positive chronic myelogenous leukemia Rinsho Ketsueki 30 1989 251 255
    • (1989) Rinsho Ketsueki , vol.30 , pp. 251-255
    • Takahira, H.1    Ideguchi, H.2    Hirata, J.3
  • 267
    • 0028018343 scopus 로고
    • Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies
    • M. Talpaz Z. Estrov H. Kantarjian Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies J Clin Invest 94 1994 1383 1389
    • (1994) J Clin Invest , vol.94 , pp. 1383-1389
    • Talpaz, M.1    Estrov, Z.2    Kantarjian, H.3
  • 268
    • 0025854383 scopus 로고
    • Interferon-alpha produces sustained cytogenetic response in chronic myelogenous leukemia. Philadelphia chromosome–positive patients
    • M. Talpaz H. Kantarjian R. Kurzrock Interferon-alpha produces sustained cytogenetic response in chronic myelogenous leukemia. Philadelphia chromosome–positive patients Ann Intern Med 114 1991 532 538
    • (1991) Ann Intern Med , vol.114 , pp. 532-538
    • Talpaz, M.1    Kantarjian, H.2    Kurzrock, R.3
  • 269
    • 0028084554 scopus 로고
    • Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway
    • T. Tauchi H.S. Boswell D. Leibowitz Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway J Exp Med 179 1994 167
    • (1994) J Exp Med , vol.179 , pp. 167
    • Tauchi, T.1    Boswell, H.S.2    Leibowitz, D.3
  • 270
  • 273
    • 0029152154 scopus 로고
    • v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway
    • K.K. Teng H. Lander J.E. Fajardo v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway J Biol Chem 270 1995 20677 20685
    • (1995) J Biol Chem , vol.270 , pp. 20677-20685
    • Teng, K.K.1    Lander, H.2    Fajardo, J.E.3
  • 274
    • 0025732159 scopus 로고
    • Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38− progenitor cells
    • L.W. Terstappen S. Huang M. Safford Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38− progenitor cells Blood 77 1991 1218 1227
    • (1991) Blood , vol.77 , pp. 1218-1227
    • Terstappen, L.W.1    Huang, S.2    Safford, M.3
  • 275
    • 0028337542 scopus 로고
    • Transcriptional activation: A complex puzzle with few easy pieces
    • R. Tjian T. Maniatis Transcriptional activation: A complex puzzle with few easy pieces Cell 77 1994 5 8
    • (1994) Cell , vol.77 , pp. 5-8
    • Tjian, R.1    Maniatis, T.2
  • 276
    • 0027371503 scopus 로고
    • Ways of minimising hematopoietic damage induced by radiation and cytostatic drugs—the possible role of inhibitors
    • M. Tubiana P. Carde E. Frindel Ways of minimising hematopoietic damage induced by radiation and cytostatic drugs—the possible role of inhibitors Radiother Oncol 29 1993 1 17
    • (1993) Radiother Oncol , vol.29 , pp. 1-17
    • Tubiana, M.1    Carde, P.2    Frindel, E.3
  • 277
    • 0025761861 scopus 로고
    • Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123
    • C. Udomsakdi C.J. Eaves H.J. Sutherland P.M. Lansdorp Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123 Exp Hematol 19 1991 338 342
    • (1991) Exp Hematol , vol.19 , pp. 338-342
    • Udomsakdi, C.1    Eaves, C.J.2    Sutherland, H.J.3    Lansdorp, P.M.4
  • 278
    • 0026742369 scopus 로고
    • Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level
    • C. Udomsakdi C.J. Eaves B. Swolin Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level Proc Natl Acad Sci USA 89 1992 6192 6196
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6192-6196
    • Udomsakdi, C.1    Eaves, C.J.2    Swolin, B.3
  • 279
    • 0026332785 scopus 로고
    • Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells
    • G. Upadhyaya S.C. Guba S.A. Sih Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells J Clin Invest 88 1991 2131 2136
    • (1991) J Clin Invest , vol.88 , pp. 2131-2136
    • Upadhyaya, G.1    Guba, S.C.2    Sih, S.A.3
  • 280
    • 9344243486 scopus 로고    scopus 로고
    • Leukemic burden in subpopulations of mobilized peripheral blood of α-interferon-resistant or -intolerant patients with chronic myeloid leukemia
    • Van Den Berg D. M. Weesman L. Murray Leukemic burden in subpopulations of mobilized peripheral blood of α-interferon-resistant or -intolerant patients with chronic myeloid leukemia Blood 87 1996 4348
    • (1996) Blood , vol.87 , pp. 4348
    • Van Den Berg, D.1    Weesman, M.2    Murray, L.3
  • 281
    • 0028084328 scopus 로고
    • The COOH-terminus of the c-abl tyrosine kinase contains distinct F-actin and G-actin binding domains with bundling activity
    • Van Etten R.A. P.K. Jackson D. Baltimore The COOH-terminus of the c-abl tyrosine kinase contains distinct F-actin and G-actin binding domains with bundling activity J Cell Biol 124 1994 325
    • (1994) J Cell Biol , vol.124 , pp. 325
    • Van Etten, R.A.1    Jackson, P.K.2    Baltimore, D.3
  • 282
    • 0024353722 scopus 로고
    • The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
    • Van Etten R.A. P.K. Jackson D. Baltimore The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization Cell 58 1989 669 678
    • (1989) Cell , vol.58 , pp. 669-678
    • Van Etten, R.A.1    Jackson, P.K.2    Baltimore, D.3
  • 283
    • 0026650764 scopus 로고
    • Direct contact between progenitors and stroma is not required for human in vitro hematopoiesis
    • C.M. Verfaillie Direct contact between progenitors and stroma is not required for human in vitro hematopoiesis Blood 79 1992 2821 2826
    • (1992) Blood , vol.79 , pp. 2821-2826
    • Verfaillie, C.M.1
  • 284
    • 0029932187 scopus 로고    scopus 로고
    • Development of a novel single LTC-IC proliferation assay that can determine the fate of LTC-IC over time
    • C.M. Verfaillie P. Catanzarro Development of a novel single LTC-IC proliferation assay that can determine the fate of LTC-IC over time Leukemia 10 1996 498 504
    • (1996) Leukemia , vol.10 , pp. 498-504
    • Verfaillie, C.M.1    Catanzarro, P.2
  • 285
    • 0028168345 scopus 로고
    • CD34+/CD33− cells reslected from MIP−1a+IL3 supplemented “stroma-noncontact” cultures are highly enriched for LTBMC-IC
    • C.M. Verfaillie J.S. Miller CD34+/CD33− cells reslected from MIP−1a+IL3 supplemented “stroma-noncontact” cultures are highly enriched for LTBMC-IC Blood 84 1994 1442 1450
    • (1994) Blood , vol.84 , pp. 1442-1450
    • Verfaillie, C.M.1    Miller, J.S.2
  • 286
    • 0025030585 scopus 로고
    • Purified primitive hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma
    • C. Verfaillie K. Blakolmer P. McGlave Purified primitive hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma J Exp Med 172 1990 509 520
    • (1990) J Exp Med , vol.172 , pp. 509-520
    • Verfaillie, C.1    Blakolmer, K.2    McGlave, P.3
  • 287
    • 0028146155 scopus 로고
    • Adhesion of committed human hematopoietic progenitors to synthetic peptides in the C-terminal heparin-binding domain of fibronectin: Cooperation between the integrin α4β1 and the CD44 adhesion receptor
    • C.M. Verfaillie A. Benis G. Iida Adhesion of committed human hematopoietic progenitors to synthetic peptides in the C-terminal heparin-binding domain of fibronectin: Cooperation between the integrin α4β1 and the CD44 adhesion receptor Blood 84 1994 1802 1812
    • (1994) Blood , vol.84 , pp. 1802-1812
    • Verfaillie, C.M.1    Benis, A.2    Iida, G.3
  • 288
    • 0029896896 scopus 로고    scopus 로고
    • Benign primitive progenitors can be selected on the basis of the CD34+/HLA-DR- phenotype in early chronic phase but not advanced phase CML
    • C.M. Verfaillie R. Bhatia W. Miller Benign primitive progenitors can be selected on the basis of the CD34+/HLA-DR- phenotype in early chronic phase but not advanced phase CML Blood 87 1996 4770 4779
    • (1996) Blood , vol.87 , pp. 4770-4779
    • Verfaillie, C.M.1    Bhatia, R.2    Miller, W.3
  • 289
    • 0025896309 scopus 로고
    • Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin
    • C.M. Verfaillie J.B. McCarthy P.B. McGlave Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin J Exp Med 174 1991 693 703
    • (1991) J Exp Med , vol.174 , pp. 693-703
    • Verfaillie, C.M.1    McCarthy, J.B.2    McGlave, P.B.3
  • 290
    • 0026441040 scopus 로고
    • Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia: Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV
    • C.M. Verfaillie J.B. McCarthy P.B. McGlave Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia: Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV J Clin Invest 90 1992 1232 1239
    • (1992) J Clin Invest , vol.90 , pp. 1232-1239
    • Verfaillie, C.M.1    McCarthy, J.B.2    McGlave, P.B.3
  • 291
    • 0026592510 scopus 로고
    • Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression
    • C.M. Verfaillie W.J. Mille K. Boyland P.B. McGlave Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression Blood 79 1992 1003 1011
    • (1992) Blood , vol.79 , pp. 1003-1011
    • Verfaillie, C.M.1    Mille, W.J.2    Boyland, K.3    McGlave, P.B.4
  • 292
    • 0028968626 scopus 로고
    • Increased neutrophil respiratory burst in bcr-null mutants
    • J.W. Voncken van Schaick H. V. Kaartinen Increased neutrophil respiratory burst in bcr-null mutants Cell 80 1995 719
    • (1995) Cell , vol.80 , pp. 719
    • Voncken, J.W.1    van Schaick, H.2    Kaartinen, V.3
  • 293
    • 0028281703 scopus 로고
    • Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice
    • J. Vormoor T. Lapidot F. Pflumio Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice Blood 83 1994 2489 2497
    • (1994) Blood , vol.83 , pp. 2489-2497
    • Vormoor, J.1    Lapidot, T.2    Pflumio, F.3
  • 294
    • 0024580388 scopus 로고
    • Comparison of erythroid progenitor cell growth in vitro in polycythemia vera and chronic myelogenous leukemia: Only polycythemia vera has endogenous colonies
    • R.S. Weinberg A. Worsley H.S. Gilbert Comparison of erythroid progenitor cell growth in vitro in polycythemia vera and chronic myelogenous leukemia: Only polycythemia vera has endogenous colonies Leuk Res 13 1989 331 338
    • (1989) Leuk Res , vol.13 , pp. 331-338
    • Weinberg, R.S.1    Worsley, A.2    Gilbert, H.S.3
  • 295
    • 0028168646 scopus 로고
    • IFN consensus sequence binding protein (ICSBP) is a conditional repressor of IFN inducible promoters
    • A. Weisz S. Kirchhoff B.Z. Levi IFN consensus sequence binding protein (ICSBP) is a conditional repressor of IFN inducible promoters International Immunology 6 1994 1125 1131
    • (1994) International Immunology , vol.6 , pp. 1125-1131
    • Weisz, A.1    Kirchhoff, S.2    Levi, B.Z.3
  • 296
    • 0026461132 scopus 로고
    • Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes
    • A. Weisz P. Marx R. Sharf Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes J Biol Chem 267 1992 25589 25596
    • (1992) J Biol Chem , vol.267 , pp. 25589-25596
    • Weisz, A.1    Marx, P.2    Sharf, R.3
  • 298
    • 0029087556 scopus 로고
    • Interferon-alpha therapy for chronic myelogenous leukemia
    • M. Wetzler H. Kantarjian R. Kurzrock M. Talpaz Interferon-alpha therapy for chronic myelogenous leukemia Am J Med 9 1995 402 411
    • (1995) Am J Med , vol.9 , pp. 402-411
    • Wetzler, M.1    Kantarjian, H.2    Kurzrock, R.3    Talpaz, M.4
  • 299
    • 0025908024 scopus 로고
    • Constitutive expression of leukemia inhibitory factor RNA by human bone marrow stromal cells and modulation by IL-1, TNF-α and TGF-β
    • M. Wetzler M. Talpaz D.G. Lowe Constitutive expression of leukemia inhibitory factor RNA by human bone marrow stromal cells and modulation by IL-1, TNF-α and TGF-β Exp Hematol 19 1991 347 352
    • (1991) Exp Hematol , vol.19 , pp. 347-352
    • Wetzler, M.1    Talpaz, M.2    Lowe, D.G.3
  • 300
    • 0027367245 scopus 로고
    • Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation
    • M. Wetzler M. Talpaz Van Etten R.A. Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation J Clin Invest 92 1993 1925
    • (1993) J Clin Invest , vol.92 , pp. 1925
    • Wetzler, M.1    Talpaz, M.2    Van Etten, R.A.3
  • 301
    • 0025851410 scopus 로고
    • Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions
    • D.A. Williams M. Rios C. Stephens Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions Nature 352 1991 438
    • (1991) Nature , vol.352 , pp. 438
    • Williams, D.A.1    Rios, M.2    Stephens, C.3
  • 302
    • 0029930378 scopus 로고    scopus 로고
    • c-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogenous leukemia
    • D. Wisniewski A. Strife E. Berman B. Clarkson c-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogenous leukemia Leukemia 10 1996 229 237
    • (1996) Leukemia , vol.10 , pp. 229-237
    • Wisniewski, D.1    Strife, A.2    Berman, E.3    Clarkson, B.4
  • 303
    • 0028205315 scopus 로고
    • A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations
    • D. Wisniewski A. Strife D. Wojciechowicz A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations Leukemia 8 1994 688 693
    • (1994) Leukemia , vol.8 , pp. 688-693
    • Wisniewski, D.1    Strife, A.2    Wojciechowicz, D.3
  • 304
    • 0026530736 scopus 로고
    • Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia
    • A.W. Wognum G. Krystal C.J. Eaves Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia Blood 79 1992 642 649
    • (1992) Blood , vol.79 , pp. 642-649
    • Wognum, A.W.1    Krystal, G.2    Eaves, C.J.3
  • 305
    • 0028239341 scopus 로고
    • The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: Its properties in comparison with those of Smg GDS
    • H. Yaku T. Sasaki Y. Takai The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: Its properties in comparison with those of Smg GDS Biochem Biophys Res Commun 198 1994 811
    • (1994) Biochem Biophys Res Commun , vol.198 , pp. 811
    • Yaku, H.1    Sasaki, T.2    Takai, Y.3
  • 306
    • 0031444245 scopus 로고    scopus 로고
    • Identification of the Abl- and rasGAP-associated 62kDa protein as a socking protein, Dok
    • T. Yamanashi D. Baltimore Identification of the Abl- and rasGAP-associated 62kDa protein as a socking protein, Dok Cell 88 1997 205 211
    • (1997) Cell , vol.88 , pp. 205-211
    • Yamanashi, T.1    Baltimore, D.2
  • 307
    • 0029834691 scopus 로고    scopus 로고
    • Growth factor–dependent survival of rodent fibroblasts requires phosphatidylinositol 3-kinase but is independent of pp70S6K activity
    • R. Yao G.M. Cooper Growth factor–dependent survival of rodent fibroblasts requires phosphatidylinositol 3-kinase but is independent of pp70S6K activity Oncogene 13 1996 343
    • (1996) Oncogene , vol.13 , pp. 343
    • Yao, R.1    Cooper, G.M.2
  • 308
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • R. Yao G.M. Cooper Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor Science 267 1995 2003
    • (1995) Science , vol.267 , pp. 2003
    • Yao, R.1    Cooper, G.M.2
  • 309
    • 0026756730 scopus 로고
    • Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction
    • A.D. Yurochko D.Y. Liu D. Eierman S. Haskill Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction Proc Natl Acad Sci USA 89 1992 9034 9038
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9034-9038
    • Yurochko, A.D.1    Liu, D.Y.2    Eierman, D.3    Haskill, S.4
  • 310
    • 0006618838 scopus 로고
    • Human CD34+ cells transplanted in utero in sheep fetuses treated with anti-human VLA4 remain “homeless” and persist in circulation
    • 4 remain “homeless” and persist in circulation Blood 84 1994 1962a
    • (1994) Blood , vol.84 , pp. 1962a
    • Zanjani, E.1    Papayannopoulou, T.2
  • 311
    • 0028080987 scopus 로고
    • Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells
    • F.C. Zeigler B.D. Bennett C.T. Jordan Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells Blood 84 1993 2422 2430
    • (1993) Blood , vol.84 , pp. 2422-2430
    • Zeigler, F.C.1    Bennett, B.D.2    Jordan, C.T.3
  • 312
    • 0027650575 scopus 로고
    • Adhesion molecules in tumor metastasis
    • B.R. Zetter Adhesion molecules in tumor metastasis Semin Cancer Biol 4 1993 219 229
    • (1993) Semin Cancer Biol , vol.4 , pp. 219-229
    • Zetter, B.R.1
  • 313
    • 0029876639 scopus 로고    scopus 로고
    • Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
    • X. Zhu M. Ohtsubo R.M. Böhmer Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein J Cell Biol 133 1996 391 403
    • (1996) J Cell Biol , vol.133 , pp. 391-403
    • Zhu, X.1    Ohtsubo, M.2    Böhmer, R.M.3
  • 314
    • 0030021649 scopus 로고    scopus 로고
    • Signal transduction and actin filament organization
    • S.H. Zigmond Signal transduction and actin filament organization Curr Opin Cell Biol 8 1996 66 73
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 66-73
    • Zigmond, S.H.1
  • 315
    • 0029037871 scopus 로고
    • Modification of rhodamine staining allows identification of hematopoietic stem cells with preferential short-term or long-term bone marrow-repopulating ability
    • J.M. Zijlmans J.W. Visser K. Kleiverda Modification of rhodamine staining allows identification of hematopoietic stem cells with preferential short-term or long-term bone marrow-repopulating ability Proc Natl Acad Sci USA 92 1995 8901 8905
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8901-8905
    • Zijlmans, J.M.1    Visser, J.W.2    Kleiverda, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.