c-kit ligand stimulates tyrosine phosphorylation of a similar pattern of phosphotyrosyl proteins in primary primitive normal hematopoietic progenitors that are constitutively phosphorylated in comparable primitive progenitors in chronic phase chronic myelogenous leukemia

Leukemia

Volumn 10, Issue 2, 1996, Pages 229-237

  Wisniewski, D ^a   Strife, A ^a   Berman, E ^a,b,c   Clarkson, B ^a,b,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Memorial Hospital for Cancer and Allied Diseases   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

c kit ligand; CML; Normal; P tyr proteins

Indexed keywords

BCR ABL PROTEIN; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; RAS PROTEIN; STEM CELL FACTOR;

ARTICLE; BLAST CELL; CASE REPORT; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0029930378     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Caspersson T, Gahrton C, Lindsten J, Zech L. Identification of the Philadelphia chromosome on a number 22 by quinacrine mustard fluorescence analysts. Exp Cell Res 1970; 63: 238-240.
2. Rowley JD. A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine, fluorescence and Giemsa staining. Nature 1973; 243: 290-293 (letter).
3. Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 1985; 315: 550-554
4. Konopka JB, Watanabe SM, Witte ON. An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 1984; 37: 1035-1042.
5. Konopka JB, Witte ON. Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products. Mol Cell Biol 1985; 5: 3116-3123.
6. Fialkow PJ, Jacobson RJ, Papayannopoulou T. Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am J Med 1977; 63: 125-130.
7. Strife A et al. Discordant maturation as the primary biological defect in chronic myelogenous leukemia. Cancer Res 1988; 48: 1035-1041.
8. Strife A et al. Characterization of lineage-negative blast subpopula-tions derived from normal and chronic myelogenous leukemia bone marrows and determination of their responsiveness to human c-kit ligand. Cancer Res 1993; 53: 401-409.
9. Strife A et al. Differences in the composition and in the efficiency of red cell production of normal and CML erythroid progenitor populations are highlighted by response to human c-kit ligand. Leukemia Res 1993; 17: 799-807.
10. Strife A et al. Proliferative potential of subpopulations of granulocyte-macrophage progenitor cells in normal subjects and chronic myelogenous leukemia patients. Blood 1983; 62: 389-397.
11. Strife A, Clarkson B. Biology of chronic myelogenous leukemia: is discordant maturation the primary defect? Semin Hematol 1988; 25: 1-19.
12. Clarkson B, Strife A. Discordant maturation in chronic myelogenous leukemia. In: Deisseroth AB, Arlinghaus RB (eds). Chronic Myelogenous Leukemia - Molecular Approaches to Research and Therapy. Marcel Dekker: New York, 1991, pp. 3-90.
13. Daley GQ, Van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 1990; 247: 824-830.
14. Rosenberg N. Murine models for human chronic myelogenous leukemia. Cancer Cells 1990; 2: 284-286.
15. Kelliher MA, McLaughlm J, Witte ON, Rosenberg N. Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and brc/abl. Proc Natl Acad Sci USA 1990; 87: 6649-6653.
16. Wisniewski D et al. A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations. Leukemia 1994; 8: 688-693.
17. Wong G et al. Molecular cloning and nucleic acid binding properties of the CAP-associated tyrosine phosphoprotein p62. Cell 1992; 69: 551-558.
18. Ellis C, Moran M, McCormick F, Pawson T. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 1990; 343: 377-381.
19. ras GTPase-activating protein. Mol Cell Biol 1991; 11: 1804-1812.
20. Kanakura Y et al. Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins. Blood 1990; 76: 706-715.
21. Halenbeck R et al. Purification, characterization and Western blot analysis of human GTPase activating protein from native and recombinant sources. J Biol Chem 1990; 265: 21922-21928.
22. Bhavsar JH, Remmler J, Lobel P. A method to increase efficiency and minimize anomalous electrophoretic transfer in protein blotting. Anal Biochem 1994; 221: 234-242.
23. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
24. Clark SS, Liang Y. Increased detection of specific tyrosine phosphoproteins correlates with tumor progression of Abelson virus-infected lymphocytes. Leukemia 1995; 9: 165-174.
25. Kumar SP, Kannan B, Clark J, Frackelton AR Jr. Increased tyrosine phosphorylation and pp62 association of the ras GTPase-activating protein during phorbol ester-induced differentiation of leukemia cells. Proc Am Assoc Cancer Res 1991; 32: 37 (abstr. 222).
26. Puil L, Pawson T. GAP and associated proteins in Philadelphia chromosome positive leukemia. Abstracts from the American Association for Cancer Research special conference on Chromosomal and Growth Factor Abnormalities in Leukemia, October 14 - 18 1990, Chatham, MA (no. B11).
27. Druker B et al. Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines. Blood 1992; 79: 2215-2220.
28. Miyazawa K et al. Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating protein and mitogen-activated protein kinase. Exp Hematol 1991; 19: 1110-1123.
29. Lerner NB et al. Monoclonal antibody YB5.B8 identifies the human c-kit protein product. Blood 1991; 77: 1876-1883.
30. Kuriu A et al. Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product. Blood 1991; 78: 2834-2840.
31. Miyazawa K et al. Membrane-bound steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form. Blood 1995; 85: 641-649.
32. Silvennoinen O et al. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci USA 1993; 90: 8429-8433.
33. Mui AL-F, Miyajima A. Interieukin-3 and granulocyte-macrophage colony-stimulating factor receptor signal transduction. Proc Soc Exp Biol Med 1994; 206: 284-288.
34. Matthews W et al. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell 1991; 65: 1143-1152.
35. Rosnet O et al. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood 1993; 82: 1110-1119.
36. Small D et al. STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc Natl Acad Sci USA 1994; 91: 459-463.
37. Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990; 61: 203-212.
38. Hirayama F, Lyman SD, Clark SC, Ogawa M. The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 1995; 85: 1762-1768.
39. Moran MF et al. Src homology region 2 domains direct protein-protein interactions in signal transduction. Proc Natl Acad Sci USA 1990; 87: 8622-6626.
40. Koch CA et al. Multiple SH2-mediated interactions in v-src-transformed cells. Mol Cell Biol 1992; 12: 1366-1374.
41. Ogawa W, Hosomi Y, Shii K, Roth RA. Evidence for two distinct 60-kilodalton substrates of the SRC tyrosine kinase. J Biol Chem 1994; 269: 29602-29608.
42. Fumagalli S, Totty NF, Hsuan JJ, Courtneidge SA. A target for Src in mitosis. Nature 1994; 368: 871-874.
43. Taylor SJ, Shalloway D. An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis. Nature 1994; 368: 867-871.
44. Pelicci G et al. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogentc signal transduction. Cell 1992; 70:93-104.
45. McGlade J et al. Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. Proc Natl Acad Sci USA 1992; 89: 8869-8873.
46. Andoniou CE, Thien CBF, Langdon WY. Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J 1994; 13: 4515-4523.
47. Marshall CJ. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Gen Dev 1994; 4: 82-89.
48. Majerus PW et al. Recent insights in phosphatidylinositol signaling. Cell 1990; 63: 459-465.
49. Metcalf D. Hematopoietic regulators: redundancy or subtlety? Blood 1993; 82: 3515-3523.
50. Williams DE et al. The Steel factor. Develop Biol 1992; 151: 368-376.
51. Galli SJ, Zsebo KM, Geissler EN. The kit ligand, stem cell factor. Adv Immunol 1994; 55: 1-96.
52. Brandt JE, Bhalla K, Hoffman R. Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 1994; 83: 1507-1514.
53. Kabarowski JHS, Allen PB, Wiedemann LM. A temperature sensitive p210BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells. EMBO J 1994; 13: 5887-5895.
54. Laneuville P, Timm M, Hudson AT. bcr/abl expression in 32D cl3(G) cells inhibits apoptosis, induced by protein tyrosine kinase inhibitors. Cancer Res 1994; 54: 1360-1366.
55. Bedi A et al. Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 1994; 83: 2038-2044.
56. Metcalf D, Nicola NA. Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors. Proc Natl Acad Sci USA 1991; 88: 6239-6243.
57. Ikuta K, Weissman IL. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc Natl Acad Sci USA 1992; 89: 1502-1506.