-
1
-
-
0023859136
-
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
-
Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988, 332:411-415.
-
(1988)
Nature
, vol.332
, pp. 411-415
-
-
Yanagisawa, M.1
Kurihara, H.2
Kimura, S.3
Tomobe, Y.4
Kobayashi, M.5
Mitsui, Y.6
Yazaki, Y.7
Goto, K.8
Masaki, T.9
-
2
-
-
0027161460
-
The endothelin family of peptides: Local hormones with diverse roles in health and disease?
-
Haynes WG, Webb DJ: The endothelin family of peptides: local hormones with diverse roles in health and disease? Clin Sci 1993, 84:485-500.
-
(1993)
Clin Sci
, vol.84
, pp. 485-500
-
-
Haynes, W.G.1
Webb, D.J.2
-
3
-
-
0030065517
-
Expression of endothelin peptides and mRNA in the human heart
-
Plumpton C, Ashby MJ, Kuc RE, O'Reilly G, Davenport AP: Expression of endothelin peptides and mRNA in the human heart. Clin Sci 1996, 90:37-46.
-
(1996)
Clin Sci
, vol.90
, pp. 37-46
-
-
Plumpton, C.1
Ashby, M.J.2
Kuc, R.E.3
O'Reilly, G.4
Davenport, A.P.5
-
5
-
-
0025823462
-
Sarafotoxin S6c: An agonist which distinguishes between endothelin receptor subtypes
-
Williams DL, Jones KL, Pettibone DJ, Lis EV, Clineschmidt BV: Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes. Biochem Biophys Res Commun 1991, 175:556-561.
-
(1991)
Biochem Biophys Res Commun
, vol.175
, pp. 556-561
-
-
Williams, D.L.1
Jones, K.L.2
Pettibone, D.J.3
Lis, E.V.4
Clineschmidt, B.V.5
-
6
-
-
0028981194
-
B receptors cause vasoconstriction of human resistance and capacitance vessels in vivo
-
B receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation 1995, 92:357-363.
-
(1995)
Circulation
, vol.92
, pp. 357-363
-
-
Haynes, W.G.1
Strachan, F.E.2
Webb, D.J.3
-
7
-
-
0028213862
-
Endothelin receptor antagonists inhibit endothelin in human skin microcirculation
-
Wenzel RR, Noll G, Lüscher TF: Endothelin receptor antagonists inhibit endothelin in human skin microcirculation. Hypertension 1994, 23:581-586.
-
(1994)
Hypertension
, vol.23
, pp. 581-586
-
-
Wenzel, R.R.1
Noll, G.2
Lüscher, T.F.3
-
8
-
-
0025275641
-
Effect of endothelin-1 in man
-
Vierhapper H, Wagner O, Nowotny P, Waldhäusl W: Effect of endothelin-1 in man. Circulation 1990, 81:1415-1418.
-
(1990)
Circulation
, vol.81
, pp. 1415-1418
-
-
Vierhapper, H.1
Wagner, O.2
Nowotny, P.3
Waldhäusl, W.4
-
9
-
-
0030054840
-
Central and regional hemodynamic effects during infusion of big endothelin-1 in healthy humans
-
Ahlborg G, Ottosson-Seeberger A, Hemsen A, Lundberg JM: Central and regional hemodynamic effects during infusion of big endothelin-1 in healthy humans. J Appl Physiol 1996, 80:1921-1927.
-
(1996)
J Appl Physiol
, vol.80
, pp. 1921-1927
-
-
Ahlborg, G.1
Ottosson-Seeberger, A.2
Hemsen, A.3
Lundberg, J.M.4
-
10
-
-
0027989765
-
Effects of endothelin-1 on renal function in humans: Implications for physiology and pathophysiology
-
Rabelink TJ, Kaasjager KAH, Boer P, Stroes EG, Braam B, Koomans HA: Effects of endothelin-1 on renal function in humans: implications for physiology and pathophysiology. Kidney Int 1994, 46:376-381.
-
(1994)
Kidney Int
, vol.46
, pp. 376-381
-
-
Rabelink, T.J.1
Kaasjager, K.A.H.2
Boer, P.3
Stroes, E.G.4
Braam, B.5
Koomans, H.A.6
-
11
-
-
0028866962
-
Interactions of nifedipine with the renovascular effects of endothelin in humans
-
Kaasjager KAH, Van Rijn HJM, Koomans HA, Rabelink TJ: Interactions of nifedipine with the renovascular effects of endothelin in humans. J Pharmacol Exp Ther 1995, 275:306-311.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 306-311
-
-
Kaasjager, K.A.H.1
Van Rijn, H.J.M.2
Koomans, H.A.3
Rabelink, T.J.4
-
12
-
-
0030047005
-
The clinical potential of endothelin receptor antagonists in cardiovascular medicine
-
Ferro CJ, Webb DJ: The clinical potential of endothelin receptor antagonists in cardiovascular medicine. Drugs 1996, 51:12-27.
-
(1996)
Drugs
, vol.51
, pp. 12-27
-
-
Ferro, C.J.1
Webb, D.J.2
-
13
-
-
0027983753
-
Contribution of endogenous generation of endothelin-1 to basal vascular tone in man
-
Haynes WG, Webb DJ: Contribution of endogenous generation of endothelin-1 to basal vascular tone in man. Lancet 1994, 344:852-854.
-
(1994)
Lancet
, vol.344
, pp. 852-854
-
-
Haynes, W.G.1
Webb, D.J.2
-
14
-
-
0029886596
-
Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in man
-
Haynes WG, Ferro CJ, O'Kane KPJ, Somerville D, Lomax CC, Webb DJ: Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in man. Circulation 1996, 93:1860-1870. This paper provides confirmation of a role for ET-1 in the regulation of forearm vascular resistance and the first evidence that ET-1 plays a key role in regulation of systemic vascular resistance and blood pressure in humans. It also shows that endothelin receptor antagonists are capable of preventing 'vasospasm' to ET-1 in a forearm model.
-
(1996)
Circulation
, vol.93
, pp. 1860-1870
-
-
Haynes, W.G.1
Ferro, C.J.2
O'Kane, K.P.J.3
Somerville, D.4
Lomax, C.C.5
Webb, D.J.6
-
15
-
-
0025894082
-
The effect of intra-arterial endothelin on resting blood flow and sympathetically mediated vasoconstriction in the forearm of man
-
Cockcroft JR, Clarke JG, Webb DJ: The effect of intra-arterial endothelin on resting blood flow and sympathetically mediated vasoconstriction in the forearm of man. Br J Clin Pharmacol 1991, 31:521-524.
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 521-524
-
-
Cockcroft, J.R.1
Clarke, J.G.2
Webb, D.J.3
-
16
-
-
0028031563
-
Direct and sympathetically mediated venoconstriction in essential hypertension: Enhanced responses to endothelin
-
Haynes WG, Hand MF, Johnstone HA, Padfield PL, Webb DJ: Direct and sympathetically mediated venoconstriction in essential hypertension: enhanced responses to endothelin. J Clin Invest 1994, 94:1359-1364.
-
(1994)
J Clin Invest
, vol.94
, pp. 1359-1364
-
-
Haynes, W.G.1
Hand, M.F.2
Johnstone, H.A.3
Padfield, P.L.4
Webb, D.J.5
-
17
-
-
0028944736
-
The pharmacology of human blood vessels in vivo
-
Webb DJ: The pharmacology of human blood vessels in vivo. J Vasc Res 1995, 32:215.
-
(1995)
J Vasc Res
, vol.32
, pp. 215
-
-
Webb, D.J.1
-
18
-
-
0025914135
-
The effects of phosphoramidon on the regional haemodynamic responses to human proendothelin [1-38] in conscious rats
-
Gardiner SM, Compton AM, Kemp PA, Bennett T: The effects of phosphoramidon on the regional haemodynamic responses to human proendothelin [1-38] in conscious rats. Br J Pharmacol 1991, 103:2009-2015.
-
(1991)
Br J Pharmacol
, vol.103
, pp. 2009-2015
-
-
Gardiner, S.M.1
Compton, A.M.2
Kemp, P.A.3
Bennett, T.4
-
19
-
-
0026668984
-
A receptor subtype in the anaesthetised rat: Effect of BQ-123 on systemic haemodynamic responses
-
A receptor subtype in the anaesthetised rat: effect of BQ-123 on systemic haemodynamic responses. Eur J Pharmacol 1992, 221:315-324.
-
(1992)
Eur J Pharmacol
, vol.221
, pp. 315-324
-
-
Douglas, S.A.1
Elliot, J.D.2
Ohlstein, E.H.3
-
20
-
-
0026593030
-
A receptor
-
A receptor. Life Sci 1992, 50:247-255.
-
(1992)
Life Sci
, vol.50
, pp. 247-255
-
-
Ihara, M.1
Noguchi, K.2
Saeki, T.3
Fukuroda, T.4
Tsuchida, S.5
Kimura, S.6
Fukami, T.7
Ishikawa, K.8
Nishikibe, M.9
Yano, M.10
-
21
-
-
0028245805
-
B-receptor antagonist, on regional haemodynamic responses to endothelins in conscious rats
-
B-receptor antagonist, on regional haemodynamic responses to endothelins in conscious rats. Br J Pharmacol 1994, 112:823-830.
-
(1994)
Br J Pharmacol
, vol.112
, pp. 823-830
-
-
Gardiner, S.M.1
Kemp, P.A.2
March, J.E.3
Bennett, T.4
-
23
-
-
0027960634
-
Characterization of receptors mediating vascular responses to endothelin-1 in the conscious rat
-
Filep JG, Clozel M, Fournier A, Földes-Filep E: Characterization of receptors mediating vascular responses to endothelin-1 in the conscious rat. Br J Pharmacol 1994, 113:845-852.
-
(1994)
Br J Pharmacol
, vol.113
, pp. 845-852
-
-
Filep, J.G.1
Clozel, M.2
Fournier, A.3
Földes-Filep, E.4
-
25
-
-
0027459416
-
Antihypertensive effect of a newly synthesized endothelin antagonist BQ123, in a genetic hypertensive model
-
Nishikibe M, Tsuchida S, Okada M, Fukuroda T, Shimamoto K, Yano M, Ishikawa K, Ikemoto F: Antihypertensive effect of a newly synthesized endothelin antagonist BQ123, in a genetic hypertensive model. Life Sci 1993, 52:717-724.
-
(1993)
Life Sci
, vol.52
, pp. 717-724
-
-
Nishikibe, M.1
Tsuchida, S.2
Okada, M.3
Fukuroda, T.4
Shimamoto, K.5
Yano, M.6
Ishikawa, K.7
Ikemoto, F.8
-
26
-
-
0026322356
-
Phosphoramidon blocks the pressor activity of big endothelin [1-39] and lowers blood pressure in spontaneously hypertensive rats
-
McMahon EG, Palomo MA, Moore WM: Phosphoramidon blocks the pressor activity of big endothelin [1-39] and lowers blood pressure in spontaneously hypertensive rats. J Cardiovasc Pharmacol 1991, 17(suppl 7):S29-S33.
-
(1991)
J Cardiovasc Pharmacol
, vol.17
, Issue.7 SUPPL.
-
-
McMahon, E.G.1
Palomo, M.A.2
Moore, W.M.3
-
28
-
-
0028283312
-
Endothelin plays a role in the maintenance of blood pressure in normotensive guinea pigs
-
Véniant M, Clozel JP, Hess P, Clozel M: Endothelin plays a role in the maintenance of blood pressure in normotensive guinea pigs. Life Sci 1994, 55:445-454.
-
(1994)
Life Sci
, vol.55
, pp. 445-454
-
-
Véniant, M.1
Clozel, J.P.2
Hess, P.3
Clozel, M.4
-
29
-
-
0027369239
-
Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist
-
Clozel M, Breu V, Burri K, Cassai JM, Fischli W, Gray GA, Hirth G, Löffler BM, Müller M, Neidhart W, Ramuz H: Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature 1993, 365:759-761.
-
(1993)
Nature
, vol.365
, pp. 759-761
-
-
Clozel, M.1
Breu, V.2
Burri, K.3
Cassai, J.M.4
Fischli, W.5
Gray, G.A.6
Hirth, G.7
Löffler, B.M.8
Müller, M.9
Neidhart, W.10
Ramuz, H.11
-
30
-
-
0028261410
-
Diuretic-natriuretic actions and pressor effects of big endothelin (1-39) in phosphoramidon treated rats
-
Hoffman A, Haramati A, Dalal I, Shuranyi E, Winaver J: Diuretic-natriuretic actions and pressor effects of big endothelin (1-39) in phosphoramidon treated rats. Proc Soc Exp Med Biol 1994, 205:168-173.
-
(1994)
Proc Soc Exp Med Biol
, vol.205
, pp. 168-173
-
-
Hoffman, A.1
Haramati, A.2
Dalal, I.3
Shuranyi, E.4
Winaver, J.5
-
31
-
-
0028285505
-
Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065
-
Warner TD, Allcock GH, Vane JR: Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065. Br J Pharmacol. 1994, 112:207-213.
-
(1994)
Br J Pharmacol.
, vol.112
, pp. 207-213
-
-
Warner, T.D.1
Allcock, G.H.2
Vane, J.R.3
-
32
-
-
0029090762
-
An endothelin-1 mediated autocrine growth loop involved in human renal tubular regeneration
-
Ong ACM, Jowett TP, Firth JD, Burton S, Karet FE, Fine LG: An endothelin-1 mediated autocrine growth loop involved in human renal tubular regeneration. Kidney Int 1995, 48:390-401.
-
(1995)
Kidney Int
, vol.48
, pp. 390-401
-
-
Ong, A.C.M.1
Jowett, T.P.2
Firth, J.D.3
Burton, S.4
Karet, F.E.5
Fine, L.G.6
-
33
-
-
0029741347
-
Human pulmonary circulation is an important site for both clearance and production of endothelin-1
-
Depuis J, Stewart DJ, Cernacek P, Gosselin G: Human pulmonary circulation is an important site for both clearance and production of endothelin-1. Circulation 1996, 94:1578-1584. This paper shows that although there is little veno-arterial difference for ET-1 across the lung, there is marked clearance of ET-1 and also, therefore, substantial production in the lung. This organ may a major source of circulating ET-1.
-
(1996)
Circulation
, vol.94
, pp. 1578-1584
-
-
Depuis, J.1
Stewart, D.J.2
Cernacek, P.3
Gosselin, G.4
-
37
-
-
0029087262
-
Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure
-
A/B receptor antagonist, bosentan, in patients with severe heart failure. The pattern of mixed reduction of pre- and after-load, without change in heart rate, is very favourable. There was no healthy control group with which to compare the haemodynamic effects, however, and the patients were studied after withdrawal from angiotensin-converting enzyme inhibitors.
-
(1995)
Lancet
, vol.346
, pp. 732-736
-
-
Kiowski, W.1
Sutsch, G.2
Hunziker, P.3
Muller, P.4
Kim, J.5
Oechlin, E.6
Schmitt, R.7
Jones, R.8
Bertel, O.9
-
38
-
-
0029813755
-
The increase in human plasma immunoreactive endothelin but not big endothelin-1 or its C-terminal fragment induced by systemic administration of the endothelin antagonist TAK-044
-
Plumpton C, Ferro CJ, Haynes WG, Webb DJ, Davenport AP: The increase in human plasma immunoreactive endothelin but not big endothelin-1 or its C-terminal fragment induced by systemic administration of the endothelin antagonist TAK-044. Br J Pharmacol 1996, 119:311-314.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 311-314
-
-
Plumpton, C.1
Ferro, C.J.2
Haynes, W.G.3
Webb, D.J.4
Davenport, A.P.5
-
39
-
-
0027447953
-
Influence of sex hormones on plasma endothelin levels
-
Polderman KH, Stehouwer CDA, Van Kamp GJ, Dekker GA, Verheugt FWA, Gooren LJG: Influence of sex hormones on plasma endothelin levels. Ann Int Med 1993, 118: 429-432.
-
(1993)
Ann Int Med
, vol.118
, pp. 429-432
-
-
Polderman, K.H.1
Stehouwer, C.D.A.2
Van Kamp, G.J.3
Dekker, G.A.4
Verheugt, F.W.A.5
Gooren, L.J.G.6
-
40
-
-
0028846641
-
Postmenopausal hormonal replacement decreases plasma levels of endothelin-1
-
Ylikorkala O, Orpana A, Puolakka J, Pyörälä T, Viinikka L: Postmenopausal hormonal replacement decreases plasma levels of endothelin-1. J Clin Endocrinol Metab 1995, 80:3384-3387.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3384-3387
-
-
Ylikorkala, O.1
Orpana, A.2
Puolakka, J.3
Pyörälä, T.4
Viinikka, L.5
-
41
-
-
0030586958
-
Racial and gender differences in endothelin-1
-
Evans RR, Phillpis BG, Singh G, Bauman JL, Gulati A: Racial and gender differences in endothelin-1. Am J Cardiol 1996, 78:486-487.
-
(1996)
Am J Cardiol
, vol.78
, pp. 486-487
-
-
Evans, R.R.1
Phillpis, B.G.2
Singh, G.3
Bauman, J.L.4
Gulati, A.5
-
42
-
-
0029797408
-
Racial differences in plasma endothelin-1 concentrations in individuals with essential hypertension
-
Ergul S, Parish DC, Puett D, Ergul A: Racial differences in plasma endothelin-1 concentrations in individuals with essential hypertension. Hypertension 1996, 28:652-655.
-
(1996)
Hypertension
, vol.28
, pp. 652-655
-
-
Ergul, S.1
Parish, D.C.2
Puett, D.3
Ergul, A.4
-
43
-
-
0027999145
-
Increased basal concentrations of plasma endothelin in borderline hypertension
-
Lemne CE, Lundeberg T, Theodorsson E, de Faire U: Increased basal concentrations of plasma endothelin in borderline hypertension. J Hypertens 1994, 12:1069-1074.
-
(1994)
J Hypertens
, vol.12
, pp. 1069-1074
-
-
Lemne, C.E.1
Lundeberg, T.2
Theodorsson, E.3
De Faire, U.4
-
44
-
-
0029055357
-
Plasma endothelin and renal endothelin are two distinct systems involved in volume homeostasis
-
Serneri GGN, Modesti PA, Cecioni I, Biagini D, Migliorini A, Costoli A, Colella A, Naldoni A, Paoletti P: Plasma endothelin and renal endothelin are two distinct systems involved in volume homeostasis. Am J Physiol 1995, 268:H1829-H1837. This is a provocative paper concerning a role for ET-1 in maintenance of blood volume. There is a clear need for experiments designed directly to address the issues raised by this work.
-
(1995)
Am J Physiol
, vol.268
-
-
Serneri, G.G.N.1
Modesti, P.A.2
Cecioni, I.3
Biagini, D.4
Migliorini, A.5
Costoli, A.6
Colella, A.7
Naldoni, A.8
Paoletti, P.9
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