The role of ETB receptors in normotensive and hypertensive rats as revealed by the non-peptide selective ETB receptor antagonist Ro 46-8443

FEBS Letters

Volumn 383, Issue 1-2, 1996, Pages 42-45

  Clozel, Martine ^a   Breu, Volker ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Endothelin; Endothelin receptor antagonist; ETB; Hypertensive rat; Nitric oxide; Receptor

Indexed keywords

4 TERT BUTYL N [6 (2,3 DIHYDROXYPROPOXY) 5 (2 METHOXYPHENOXY) 2 (4 METHOXYPHENOXY)PYRIMIDIN 4 YL]BENZENESULFONAMIDE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DEOXYCORTICOSTERONE ACETATE; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; N(G) NITROARGININE; NITRIC OXIDE; RO 46 8443; SARAFOTOXIN S6C; UNCLASSIFIED DRUG; ARGININE; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE; DRUG DERIVATIVE; ENDOTHELIN RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PYRIMIDINE DERIVATIVE; RO 46-8443; SARAFOTOXINS S6; SULFONAMIDE; VIPER VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; HYPERTENSION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; PATHOPHYSIOLOGY; PHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANIMALS; ARGININE; BLOOD PRESSURE; HYPERTENSION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PEPTIDES, CYCLIC; PYRIMIDINES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SULFONAMIDES; VIPER VENOMS;

EID: 0029669946     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00212-8     Document Type: Article

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