-
1
-
-
0028929988
-
Replacement of the p16/CDKN2 gene suppresses human glioma cell growth
-
Arap W, Nishikawa R, Furnari F, Cavenee WK, Huang HJ: Replacement of the p16/CDKN2 gene suppresses human glioma cell growth. Cancer Res 55:1351-1355, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1351-1355
-
-
Arap, W.1
Nishikawa, R.2
Furnari, F.3
Cavenee, W.K.4
Huang, H.J.5
-
3
-
-
0028967830
-
Cyclin D1 oncoprotein accumulates in malignancies of diverse histogenesis
-
Bartkova J, Lukas J, Strauss M, Bartek J: Cyclin D1 oncoprotein accumulates in malignancies of diverse histogenesis. Oncogene 10:775-778, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 775-778
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
4
-
-
0029971218
-
Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins
-
Beijersbergen RL, Bernards R: Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins. Biochim Biophys Acta 1287:103-120, 1996.
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 103-120
-
-
Beijersbergen, R.L.1
Bernards, R.2
-
5
-
-
0028928540
-
A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma
-
Bhatia K, Fan S, Spangler G, Weintraub M, O'Connor PM, Judde JG, Magrath I: A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma. Cancer Res 55:1431-1435, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1431-1435
-
-
Bhatia, K.1
Fan, S.2
Spangler, G.3
Weintraub, M.4
O'Connor, P.M.5
Judde, J.G.6
Magrath, I.7
-
6
-
-
0030028947
-
Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates anchorage-dependent expression of cyclin A
-
Bohmer RM, Scharf E, Assoian RK: Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates anchorage-dependent expression of cyclin A. Mol Biol Cell 7:101-111, 1996.
-
(1996)
Mol Biol Cell
, vol.7
, pp. 101-111
-
-
Bohmer, R.M.1
Scharf, E.2
Assoian, R.K.3
-
7
-
-
0024439444
-
The retinoblastoma protein is phosphorylated during specific phases of cell cycle
-
Buchovich K, Duffy LA, Harlow E: The retinoblastoma protein is phosphorylated during specific phases of cell cycle. Cell 58: 1097-1105, 1989.
-
(1989)
Cell
, vol.58
, pp. 1097-1105
-
-
Buchovich, K.1
Duffy, L.A.2
Harlow, E.3
-
8
-
-
0027280084
-
Expression and amplification of cyclin genes in human breast cancer
-
Buckley MF, Sweeney KJ, Hamilton JA, Sini RL, Manning DL, Nicholson RI, deFazio A, Watts CK, Musgrove EA, Sutherland RL: Expression and amplification of cyclin genes in human breast cancer. Oncogene 8:2127-2133, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 2127-2133
-
-
Buckley, M.F.1
Sweeney, K.J.2
Hamilton, J.A.3
Sini, R.L.4
Manning, D.L.5
Nicholson, R.I.6
DeFazio, A.7
Watts, C.K.8
Musgrove, E.A.9
Sutherland, R.L.10
-
9
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the (MTS1) gene in pancreatic adenocarcinoma
-
Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE: Frequent somatic mutations and homozygous deletions of the (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 8:27-32, 1994.
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
10
-
-
0020518746
-
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
-
Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie B, Murphree AL, Strong LC, White RL: Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305:779-784, 1983.
-
(1983)
Nature
, vol.305
, pp. 779-784
-
-
Cavenee, W.K.1
Dryja, T.P.2
Phillips, R.A.3
Benedict, W.F.4
Godbout, R.5
Gallie, B.6
Murphree, A.L.7
Strong, L.C.8
White, R.L.9
-
11
-
-
9444242683
-
Shared role of the pRb-related p130 and p107 proteins in limb development
-
Cobrink D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T: Shared role of the pRb-related p130 and p107 proteins in limb development. Genes Dev 10:1633-1644, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 1633-1644
-
-
Cobrink, D.1
Lee, M.H.2
Hannon, G.3
Mulligan, G.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Beach, D.8
Weinberg, R.A.9
Jacks, T.10
-
12
-
-
0029967152
-
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromosome condensation
-
Costello JF, Berger MS, Huang HJ, Cavenee WK: Silencing of p16/CDKN2 expression in human gliomas by methylation and chromosome condensation. Cancer Res 56:2405-2410, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 2405-2410
-
-
Costello, J.F.1
Berger, M.S.2
Huang, H.J.3
Cavenee, W.K.4
-
13
-
-
0024418207
-
The product of the retinoblastoma gene has properties of a cell cycle regulatory element
-
DeCaprio JA, Ludlow JW, Lynch D, Furukawa Y, Griffin J, Pinwica-Worms H, Huang C, Livingston DM: The product of the retinoblastoma gene has properties of a cell cycle regulatory element. Cell 58:1085-1095, 1989.
-
(1989)
Cell
, vol.58
, pp. 1085-1095
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Lynch, D.3
Furukawa, Y.4
Griffin, J.5
Pinwica-Worms, H.6
Huang, C.7
Livingston, D.M.8
-
15
-
-
0030728496
-
Cyclin and cyclin-dependent kinase expression in human astrocytoma cell lines
-
Dirks PB, Hubbard SL, Murakami M, Rutka JT: Cyclin and cyclin-dependent kinase expression in human astrocytoma cell lines. J Neuropath Exp Neurol 56:291-300, 1997.
-
(1997)
J Neuropath Exp Neurol
, vol.56
, pp. 291-300
-
-
Dirks, P.B.1
Hubbard, S.L.2
Murakami, M.3
Rutka, J.T.4
-
16
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors
-
Donehower LA, Harvey M, Slage BT, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356: 215-221, 1992.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slage, B.T.3
McArthur, M.J.4
Montgomery C.A., Jr.5
Butel, J.S.6
Bradley, A.7
-
17
-
-
0028935143
-
Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization
-
Dreyling MH, Bohlander SK, Adeyanju MO, Olopade OI: Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization. Cancer Res 55:984-988, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 984-988
-
-
Dreyling, M.H.1
Bohlander, S.K.2
Adeyanju, M.O.3
Olopade, O.I.4
-
18
-
-
0028220204
-
1 arrest
-
1 arrest. Cell 76:1013-1023, 1994.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
-
19
-
-
0028980058
-
Cyclins as markers of proliferation: Immunocytochemical studies in breast cancer
-
Dutta A, Chandra R, Leiter LM, Lester S: Cyclins as markers of proliferation: Immunocytochemical studies in breast cancer. Proc Natl Acad Sci U SA 92:5386-5390, 1995.
-
(1995)
Proc Natl Acad Sci U SA
, vol.92
, pp. 5386-5390
-
-
Dutta, A.1
Chandra, R.2
Leiter, L.M.3
Lester, S.4
-
20
-
-
0028294605
-
1 arrest and apoptosis
-
1 arrest and apoptosis. Cancer Res 54:1169-1174, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wand, Y.10
Winman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Elledge, S.J.14
Kinzler, K.W.15
Vogelstein, B.16
-
21
-
-
0027359827
-
WAF 1: A potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer E, Kinzler KW, Vogelstein B: WAF 1: A potential mediator of p53 tumor suppression. Cell 75:817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, E.8
Kinzler, K.W.9
Vogelstein, B.10
-
22
-
-
0028075611
-
CDK inhibitors: On the threshold of checkpoints and development
-
Elledge SJ, Harper JW: CDK inhibitors: On the threshold of checkpoints and development. Curr Opin Cell Biol 6:847-852, 1994.
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 847-852
-
-
Elledge, S.J.1
Harper, J.W.2
-
23
-
-
0028009849
-
The cell cycle and the retinoblastoma protein family
-
Ewen ME: The cell cycle and the retinoblastoma protein family. Cancer Metastasis Rev 13:45-66, 1994.
-
(1994)
Cancer Metastasis Rev
, vol.13
, pp. 45-66
-
-
Ewen, M.E.1
-
25
-
-
15844384256
-
kip1-deficient mice
-
kip1-deficient mice. Cell 85:733-744, 1996.
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.H.8
Broudy, V.9
Perlmutter, R.M.10
Kaushansky, K.11
Roberts, J.M.12
-
26
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG, Livingston DM, Orkin SH, Greenberg ME: E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85:549-561, 1996.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.Y.2
Kuo, F.3
Zubiaga, A.M.4
Kaelin, W.G.5
Livingston, D.M.6
Orkin, S.H.7
Greenberg, M.E.8
-
27
-
-
0027994603
-
A novel cyclin associates with MO15/ CDK7 to form the CDK-activating kinase
-
Fisher RP, Morgan DO: A novel cyclin associates with MO15/ CDK7 to form the CDK-activating kinase. Cell 78:713-724, 1994.
-
(1994)
Cell
, vol.78
, pp. 713-724
-
-
Fisher, R.P.1
Morgan, D.O.2
-
28
-
-
0029995766
-
A license to kill
-
Fraser A, Evan G: A license to kill. Cell 85:781-784, 1996.
-
(1996)
Cell
, vol.85
, pp. 781-784
-
-
Fraser, A.1
Evan, G.2
-
29
-
-
0021212003
-
Cell cycle analysis of a proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
-
Gerdes J, Lemke H, Baish H, Wacker H-H, Schwab U, Stein H: Cell cycle analysis of a proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133:1710-1715, 1984.
-
(1984)
J Immunol
, vol.133
, pp. 1710-1715
-
-
Gerdes, J.1
Lemke, H.2
Baish, H.3
Wacker, H.-H.4
Schwab, U.5
Stein, H.6
-
30
-
-
0020694123
-
Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
-
Gerdes J, Schwab U, Lemke H, Stein H: Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31:13-20, 1983.
-
(1983)
Int J Cancer
, vol.31
, pp. 13-20
-
-
Gerdes, J.1
Schwab, U.2
Lemke, H.3
Stein, H.4
-
31
-
-
0028641184
-
Mutation rate of CDKN2 gene in malignant glioma
-
Giani C, Finocchiaro G: Mutation rate of CDKN2 gene in malignant glioma. Cancer Res 54:6338-6339, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 6338-6339
-
-
Giani, C.1
Finocchiaro, G.2
-
32
-
-
0028331092
-
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
-
Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, Barnes D, Peters G: Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 54:1812-1817, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1812-1817
-
-
Gillett, C.1
Fantl, V.2
Smith, R.3
Fisher, C.4
Bartek, J.5
Dickson, C.6
Barnes, D.7
Peters, G.8
-
33
-
-
0027978970
-
Unscheduled expression of cyclin B1 and cyclin e in several leukemic and solid tumor cell lines
-
Gong J, Ardelt B, Tragnos F, Darzynkiewicz Z: Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. Cancer Res 54:4285-4288, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4285-4288
-
-
Gong, J.1
Ardelt, B.2
Tragnos, F.3
Darzynkiewicz, Z.4
-
34
-
-
0027308761
-
Molecular characterization of the retinoblastoma susceptibility gene
-
Goodrich DW, Lee WH: Molecular characterization of the retinoblastoma susceptibility gene. Biochim Biophys Acta 1155:43-61, 1993.
-
(1993)
Biochim Biophys Acta
, vol.1155
, pp. 43-61
-
-
Goodrich, D.W.1
Lee, W.H.2
-
35
-
-
0025880916
-
1/S control of anchorage-independent growth in the fibroblast cell cycle
-
1/S control of anchorage-independent growth in the fibroblast cell cycle. J Cell Biol 115:1419-1425, 1991.
-
(1991)
J Cell Biol
, vol.115
, pp. 1419-1425
-
-
Guadagno, T.M.1
Assoian, R.K.2
-
36
-
-
0027752979
-
A link between cyclin a expression and adhesion-dependent cell cycle progression
-
Guadagno TM, Ohtsubo M, Roberts JM, Assoian RK: A link between cyclin A expression and adhesion-dependent cell cycle progression. Science 262:1572-1575, 1993.
-
(1993)
Science
, vol.262
, pp. 1572-1575
-
-
Guadagno, T.M.1
Ohtsubo, M.2
Roberts, J.M.3
Assoian, R.K.4
-
37
-
-
0028168242
-
INK4B is a potential effector of TGF-β-induced cell cycle arrest
-
INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261, 1994.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
39
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell LH, Kastan MB: Cell cycle control and cancer. Science 266:1821-1828, 1994.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
40
-
-
0028937476
-
Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin
-
Harvey M, Vogel H, Lee EY, Bradley A, Donehower LA: Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin. Cancer Res 55:1146-1151, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1146-1151
-
-
Harvey, M.1
Vogel, H.2
Lee, E.Y.3
Bradley, A.4
Donehower, L.A.5
-
41
-
-
0028061974
-
CDK4 amplification is an alternative mechanism to p16 homozygous deletion in glioma cell lines
-
He J, Allen JR, Collins VP: CDK4 amplification is an alternative mechanism to p16 homozygous deletion in glioma cell lines. Cancer Res 54:5804-5807, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 5804-5807
-
-
He, J.1
Allen, J.R.2
Collins, V.P.3
-
42
-
-
0028275998
-
A cell cycle regulated inhibitor of cyclin-dependent kinases
-
Hengst L, Dulic V, Slingerland J, Lees E, Reed SI: A cell cycle regulated inhibitor of cyclin-dependent kinases. Proc Natl Acad Sci U S A 91:5291-5295, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 5291-5295
-
-
Hengst, L.1
Dulic, V.2
Slingerland, J.3
Lees, E.4
Reed, S.I.5
-
43
-
-
0027967944
-
Rules to replicate by
-
Heichman KA, Roberts JM: Rules to replicate by. Cell 79:557-562, 1994.
-
(1994)
Cell
, vol.79
, pp. 557-562
-
-
Heichman, K.A.1
Roberts, J.M.2
-
45
-
-
0028153681
-
Function of a human cyclin gene as an oncogene
-
Hinds PW, Dowdy SF, Eaton EN, Arnold A, Weinberg RA: Function of a human cyclin gene as an oncogene. Proc Natl Acad Sci U S A 91:709-713, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 709-713
-
-
Hinds, P.W.1
Dowdy, S.F.2
Eaton, E.N.3
Arnold, A.4
Weinberg, R.A.5
-
46
-
-
0018695644
-
Cell kinetic analyses of human malignant brain tumors (gliomas)
-
Hoshino T, Wilson CB: Cell kinetic analyses of human malignant brain tumors (gliomas). Cancer 44:956-962, 1979.
-
(1979)
Cancer
, vol.44
, pp. 956-962
-
-
Hoshino, T.1
Wilson, C.B.2
-
47
-
-
0019959053
-
Clonogenicity of multiple populations of human glioma cells in vitro sorted by DNA content
-
Hoshino T, Knebel KD, Rosenblum ML, Dougherty DV, Wilson CB: Clonogenicity of multiple populations of human glioma cells in vitro sorted by DNA content. Cancer 50:997-1002, 1982.
-
(1982)
Cancer
, vol.50
, pp. 997-1002
-
-
Hoshino, T.1
Knebel, K.D.2
Rosenblum, M.L.3
Dougherty, D.V.4
Wilson, C.B.5
-
48
-
-
0022486960
-
In situ cell kinetics studies on human neuroectodermal tumors with bromodeoxyuridine labeling
-
Hoshino T, Nagashima T, Murovic JA, Wilson CB, Edwards MSG, Gutin PH, Davis RL, DeArmond SJ: In situ cell kinetics studies on human neuroectodermal tumors with bromodeoxyuridine labeling. J Neurosurg 64:453-459, 1986.
-
(1986)
J Neurosurg
, vol.64
, pp. 453-459
-
-
Hoshino, T.1
Nagashima, T.2
Murovic, J.A.3
Wilson, C.B.4
Msg, E.5
Gutin, P.H.6
Davis, R.L.7
Dearmond, S.J.8
-
49
-
-
0018102985
-
The distribution of nuclear DNA from human brain tumor cells: Flow cytometric studies
-
Hoshino T, Nomura K, Wilson CB, Knebel KD, Gray JW: The distribution of nuclear DNA from human brain tumor cells: Flow cytometric studies. J Neurosurg 49:13-21, 1978.
-
(1978)
J Neurosurg
, vol.49
, pp. 13-21
-
-
Hoshino, T.1
Nomura, K.2
Wilson, C.B.3
Knebel, K.D.4
Gray, J.W.5
-
50
-
-
0028174064
-
Heterozygous Rb-1Δ20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance
-
Hu N, Gutsmann A, Herbert DC, Bradley A, Lee WH, Lee EY: Heterozygous Rb-1Δ20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance. Oncogene 9:1021-1027, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1021-1027
-
-
Hu, N.1
Gutsmann, A.2
Herbert, D.C.3
Bradley, A.4
Lee, W.H.5
Lee, E.Y.6
-
51
-
-
0027938209
-
Cyclins and cancer: II - Cyclin D and CDK inhibitors come of age
-
Hunter T, Pines J: Cyclins and cancer: II - Cyclin D and CDK inhibitors come of age. Cell 79:573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
52
-
-
0028100903
-
Germline p16 mutations in familial melanoma
-
Hussussian CJ, Struewing JP, Golstein AM, Higgins RA, Ally DS, Sheahan MD, Clark WH Jr, Tucker MA, Dracopoli NC: Germline p16 mutations in familial melanoma. Nat Genet 8:15-21, 1994.
-
(1994)
Nat Genet
, vol.8
, pp. 15-21
-
-
Hussussian, C.J.1
Struewing, J.P.2
Golstein, A.M.3
Higgins, R.A.4
Ally, D.S.5
Sheahan, M.D.6
Clark W.H., Jr.7
Tucker, M.A.8
Dracopoli, N.C.9
-
53
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA: Effects of an Rb mutation in the mouse. Nature 359:295-300, 1992.
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
54
-
-
0028169371
-
PRAD1/cyclin D1 gene amplification correlates with mRNA overexpression and tumor progression in human laryngeal carcinomas
-
Jares P, Fernandez PL, Campo E, Nadal A, Bosch F, Aiza G, Nayach I, Traserra J, Cardesa A: PRAD1/cyclin D1 gene amplification correlates with mRNA overexpression and tumor progression in human laryngeal carcinomas. Cancer Res 54:4813-4817, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4813-4817
-
-
Jares, P.1
Fernandez, P.L.2
Campo, E.3
Nadal, A.4
Bosch, F.5
Aiza, G.6
Nayach, I.7
Traserra, J.8
Cardesa, A.9
-
55
-
-
0028618304
-
Deletion of p16 and p15 in brain tumors
-
Jen JJ, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, Wilson JK, Kinzler K, Vogelstein B: Deletion of p16 and p15 in brain tumors. Cancer Res 54:6353-6358, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 6353-6358
-
-
Jen, J.J.1
Harper, J.W.2
Bigner, S.H.3
Bigner, D.D.4
Papadopoulos, N.5
Markowitz, S.6
Wilson, J.K.7
Kinzler, K.8
Vogelstein, B.9
-
56
-
-
0026720446
-
Amplification and expression of human cyclin D gene in esophageal cancer
-
Jiang W, Kahn SM, Tomita N, Zhang YJ, Lu SH, Weinstein IB: Amplification and expression of human cyclin D gene in esophageal cancer. Cancer Res 52:2980-2983, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2980-2983
-
-
Jiang, W.1
Kahn, S.M.2
Tomita, N.3
Zhang, Y.J.4
Lu, S.H.5
Weinstein, I.B.6
-
57
-
-
0027494864
-
Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression, gene expression
-
Jiang W, Kahn SM, Zhou P, Zhang YJ, Cacace AM, Infante AS, Doi S, Santella RM, Weinstein IB: Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression, gene expression. Oncogene 8:3447-3457, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 3447-3457
-
-
Jiang, W.1
Kahn, S.M.2
Zhou, P.3
Zhang, Y.J.4
Cacace, A.M.5
Infante, A.S.6
Doi, S.7
Santella, R.M.8
Weinstein, I.B.9
-
58
-
-
0027429033
-
Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer
-
Jiang W, Zhang YJ, Kahn SM, Hollstein MC, Santella RM, Lu SH, Harris CC, Montesano R, Weinstein IB: Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer. Proc Natl Acad Sci U S A 90:9026-9030, 1993.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9026-9030
-
-
Jiang, W.1
Zhang, Y.J.2
Kahn, S.M.3
Hollstein, M.C.4
Santella, R.M.5
Lu, S.H.6
Harris, C.C.7
Montesano, R.8
Weinstein, I.B.9
-
59
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
Johnson DG, Schwarz JK, Cress WD, Nevins JR: Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365:349-352, 1993.
-
(1993)
Nature
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
60
-
-
0028121279
-
A cell cycle regulator potentially involved in the genesis of many tumor types
-
Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RD, Johnson BE, Skolnick MH: A cell cycle regulator potentially involved in the genesis of many tumor types. Science 264:436-440, 1994.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day, R.D.8
Johnson, B.E.9
Skolnick, M.H.10
-
61
-
-
0028085975
-
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
-
Kamb A, Shattuck-Eidens D, Eeles R, Liu Q, Gruis NA, Ding W, Hussey C, Tran T, Miki Y, Weaver-Feldhaus J: Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat Genet 8:22-26, 1994.
-
(1994)
Nat Genet
, vol.8
, pp. 22-26
-
-
Kamb, A.1
Shattuck-Eidens, D.2
Eeles, R.3
Liu, Q.4
Gruis, N.A.5
Ding, W.6
Hussey, C.7
Tran, T.8
Miki, Y.9
Weaver-Feldhaus, J.10
-
62
-
-
0029007867
-
Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies
-
Kawamata N, Morosetti R, Miller CW, Park D, Spirin KS, Nakamaki T, Takeuchi S, Hatta Y, Simpson J, Wilczynski S, Lee YY, Bartam CR, Koeffler HP: Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res 55:2266-2269, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 2266-2269
-
-
Kawamata, N.1
Morosetti, R.2
Miller, C.W.3
Park, D.4
Spirin, K.S.5
Nakamaki, T.6
Takeuchi, S.7
Hatta, Y.8
Simpson, J.9
Wilczynski, S.10
Lee, Y.Y.11
Bartam, C.R.12
Koeffler, H.P.13
-
63
-
-
0028329172
-
Apoptosis: Its significance in cancer and cancer therapy
-
Kerr JF, Winterford CM, Harmon BV: Apoptosis: Its significance in cancer and cancer therapy. Cancer 73:2013-2026, 1994.
-
(1994)
Cancer
, vol.73
, pp. 2013-2026
-
-
Kerr, J.F.1
Winterford, C.M.2
Harmon, B.V.3
-
64
-
-
0027530449
-
Redundant cyclin overexpression and gene amplification in breast cancer cells
-
Keyomarsi K, Pardee AB: Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci USA 90:1112-1116, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1112-1116
-
-
Keyomarsi, K.1
Pardee, A.B.2
-
65
-
-
0027955197
-
Cyclin E: A potential prognostic marker for breast cancer
-
Keyomarsi K, O'Leary N, Molnar G, Lees E, Fingert HJ, Pardee AB: Cyclin E: A potential prognostic marker for breast cancer. Cancer Res 54:380-385, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 380-385
-
-
Keyomarsi, K.1
O'Leary, N.2
Molnar, G.3
Lees, E.4
Fingert, H.J.5
Pardee, A.B.6
-
66
-
-
0027454445
-
Coamplification of CDK4 gene with MDM2 and GLI in human sarcomas
-
Khatib ZA, Matsushime H, Valentine M, Shapiro DN, Sherr CJ, Look AT: Coamplification of CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res 53:5535-5541, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 5535-5541
-
-
Khatib, Z.A.1
Matsushime, H.2
Valentine, M.3
Shapiro, D.N.4
Sherr, C.J.5
Look, A.T.6
-
68
-
-
15844415946
-
kip1
-
kip1. Cell 85:721-732, 1996.
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
69
-
-
0024847839
-
Proliferation activity in pituitary adenomas: Measurement by monoclonal antibody Ki-67
-
Knosp E, Kitz K, Perneczky A: Proliferation activity in pituitary adenomas: Measurement by monoclonal antibody Ki-67. Neurosurgery 25:927-930, 1989.
-
(1989)
Neurosurgery
, vol.25
, pp. 927-930
-
-
Knosp, E.1
Kitz, K.2
Perneczky, A.3
-
70
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG: Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci U S A 68:820-823, 1971.
-
(1971)
Proc Natl Acad Sci U S A
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
71
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, Prives C: p53: Puzzle and paradigm. Genes Dev 10:1054-1072, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
72
-
-
0028363665
-
Mitosis: Back to basics
-
Koshland D: Mitosis: Back to basics. Cell 77:951-954, 1994.
-
(1994)
Cell
, vol.77
, pp. 951-954
-
-
Koshland, D.1
-
73
-
-
0030032928
-
Mutations in the p16 gene in gliomas
-
Kyritsis AP, Zhang B, Zhang W, Xiao M, Takeshima H, Bondy ML, Cunningham JE, Levin VA, Bruner J: Mutations in the p16 gene in gliomas. Oncogene 12:63-67, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 63-67
-
-
Kyritsis, A.P.1
Zhang, B.2
Zhang, W.3
Xiao, M.4
Takeshima, H.5
Bondy, M.L.6
Cunningham, J.E.7
Levin, V.A.8
Bruner, J.9
-
75
-
-
0027273790
-
Amplification of cyclin genes in colorectal carcinoma
-
Leach FS, Elledge SJ, Sherr CJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B: Amplification of cyclin genes in colorectal carcinoma. Cancer Res 53:1986-1989, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 1986-1989
-
-
Leach, F.S.1
Elledge, S.J.2
Sherr, C.J.3
Willson, J.K.4
Markowitz, S.5
Kinzler, K.W.6
Vogelstein, B.7
-
76
-
-
0023106062
-
Human retinoblastoma susceptibility gene: Cloning, identification, and sequence
-
Lee WH, Bookstein R, Hong F, Young LJ, Shew JY, Lee EY: Human retinoblastoma susceptibility gene: Cloning, identification, and sequence. Science 235:1394-1399, 1987.
-
(1987)
Science
, vol.235
, pp. 1394-1399
-
-
Lee, W.H.1
Bookstein, R.2
Hong, F.3
Young, L.J.4
Shew, J.Y.5
Lee, E.Y.6
-
77
-
-
0029736909
-
Targeted disruption of p107: Functional overlap between p107 and pRb
-
Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T: Targeted disruption of p107: Functional overlap between p107 and pRb. Genes Dev 10:1621-1632, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 1621-1632
-
-
Lee, M.H.1
Williams, B.O.2
Mulligan, G.3
Mukai, S.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Jacks, T.8
-
78
-
-
0028034775
-
Transcriptioital repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product
-
Li Y, Nichols MA, Shay JW, Xiong Y: Transcriptioital repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product. Cancer Res 54:6078-6082, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 6078-6082
-
-
Li, Y.1
Nichols, M.A.2
Shay, J.W.3
Xiong, Y.4
-
79
-
-
0028074603
-
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
-
Li R, Waga S, Hannon GJ, Beach D, Stillman B: Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature 371:534-537, 1994.
-
(1994)
Nature
, vol.371
, pp. 534-537
-
-
Li, R.1
Waga, S.2
Hannon, G.J.3
Beach, D.4
Stillman, B.5
-
80
-
-
0028049592
-
Cyclin D1/ bcl-1 cooperates with myc genes in the generation of B-cell lymphomas in transgenic mice
-
Lovec H, Grzeschiczek A, Kowalski MB, Moreoy T: Cyclin D1/ bcl-1 cooperates with myc genes in the generation of B-cell lymphomas in transgenic mice. EMBO J 13:3487-3495, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 3487-3495
-
-
Lovec, H.1
Grzeschiczek, A.2
Kowalski, M.B.3
Moreoy, T.4
-
81
-
-
0028279059
-
1
-
1. J Cell Biol 125: 625-638, 1994.
-
(1994)
J Cell Biol
, vol.125
, pp. 625-638
-
-
Lukas, J.1
Muller, H.2
Bartkova, J.3
Spitkovsky, D.4
Kjerulff, A.5
Jansen-Durr, P.6
Strauss, M.7
Bartek, J.8
-
82
-
-
0027958344
-
Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumor cell lines
-
Lukas J, Pagano M, Statkova Z, Draetta G, Bartek J: Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumor cell lines. Oncogene 9:707-718, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 707-718
-
-
Lukas, J.1
Pagano, M.2
Statkova, Z.3
Draetta, G.4
Bartek, J.5
-
83
-
-
0026059515
-
Tumor suppressor genes
-
Marshall CJ: Tumor suppressor genes. Cell 64:313-326, 1991.
-
(1991)
Cell
, vol.64
, pp. 313-326
-
-
Marshall, C.J.1
-
84
-
-
0028268284
-
D-type cyclin-dependent kinase activity in mammalian cells
-
Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sheer CJ, Kato JY: D-type cyclin-dependent kinase activity in mammalian cells. Mol Cell Biol 14:2066-2076, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2066-2076
-
-
Matsushime, H.1
De Quelle2
Shurtleff, S.A.3
Shibuya, M.4
Sheer, C.J.5
Kato, J.Y.6
-
86
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D: 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers. Nat Med 1:686-692, 1995.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
87
-
-
0028181760
-
1 kinase activity for CDK6, a novel cyclin D partner
-
1 kinase activity for CDK6, a novel cyclin D partner. Mol Cell Biol 14:2077-2086, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2077-2086
-
-
Meyerson, M.1
Harlow, E.2
-
88
-
-
0028953560
-
Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck
-
Michalides R, van Veelen N, Hart A, Loftus B, Wientjens E, Balm A: Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck. Cancer Res 55:975-978, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 975-978
-
-
Michalides, R.1
Van Veelen, N.2
Hart, A.3
Loftus, B.4
Wientjens, E.5
Balm, A.6
-
89
-
-
0027408679
-
DNA tumor virus transforming proteins and the cell cycle
-
Moran E: DNA tumor virus transforming proteins and the cell cycle. Curr Opin Genet Dev 3:63-70, 1993.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 63-70
-
-
Moran, E.1
-
90
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO: Principles of CDK regulation. Nature 374:131-134, 1995.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
91
-
-
0025806904
-
A novel cyclin encoded by a bcl-1 linked-candidate oncogene
-
Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A: A novel cyclin encoded by a bcl-1 linked-candidate oncogene. Nature 350:512-515, 1991.
-
(1991)
Nature
, vol.350
, pp. 512-515
-
-
Motokura, T.1
Bloom, T.2
Kim, H.G.3
Juppner, H.4
Ruderman, J.V.5
Kronenberg, H.M.6
Arnold, A.7
-
92
-
-
0028930619
-
MTS1/p16/CDKN2 lesions in primary glioblastomas multiforme
-
Moulton T, Samara G, Chung WY, Yuan L, Desai R, Sisti M, Bruce J, Tycko B: MTS1/p16/CDKN2 lesions in primary glioblastomas multiforme. Am J Pathol 146:613-619, 1995.
-
(1995)
Am J Pathol
, vol.146
, pp. 613-619
-
-
Moulton, T.1
Samara, G.2
Chung, W.Y.3
Yuan, L.4
Desai, R.5
Sisti, M.6
Bruce, J.7
Tycko, B.8
-
93
-
-
0026703325
-
Creative blocks: Cell-cycle checkpoints and feedback controls
-
Murray A: Creative blocks: Cell-cycle checkpoints and feedback controls. Nature 359:599-604, 1992.
-
(1992)
Nature
, vol.359
, pp. 599-604
-
-
Murray, A.1
-
95
-
-
0030010591
-
kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720, 1996.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
96
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins JR: E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424-429, 1992.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
97
-
-
0027585031
-
Targets of cyclin-dependent kinases
-
Nigg EA: Targets of cyclin-dependent kinases. Curr Opin Cell Biol 5:187-193, 1993.
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 187-193
-
-
Nigg, E.A.1
-
98
-
-
0029317904
-
Cyclin-dependent protein kinases: Key regulators of the cell cycle
-
Nigg EA: Cyclin-dependent protein kinases: Key regulators of the cell cycle. Bioessays 17:471-480, 1995.
-
(1995)
Bioessays
, vol.17
, pp. 471-480
-
-
Nigg, E.A.1
-
99
-
-
0028292294
-
Amplification and overexpression of the cyclin D1 gene in aggressive human hepatocellular carcinoma
-
Nishida N, Fukuda Y, Komeda T, Kita R, Sando T, Furukawa M, Amenomori M, Shibagaki I, Nakao K, Ikenaga M, Ishizaki K: Amplification and overexpression of the cyclin D1 gene in aggressive human hepatocellular carcinoma. Cancer Res 54:1941-1945, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1941-1945
-
-
Nishida, N.1
Fukuda, Y.2
Komeda, T.3
Kita, R.4
Sando, T.5
Furukawa, M.6
Amenomori, M.7
Shibagaki, I.8
Nakao, K.9
Ikenaga, M.10
Ishizaki, K.11
-
100
-
-
0028986612
-
Loss of p16 expression is frequent in high grade glioma
-
Nishikawa R, Furnari FB, Lin H, Arap W, Berger MS, Cavenee WK, Huang HJ: Loss of p16 expression is frequent in high grade glioma. Cancer Res 55:1941-1945, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1941-1945
-
-
Nishikawa, R.1
Furnari, F.B.2
Lin, H.3
Arap, W.4
Berger, M.S.5
Cavenee, W.K.6
Huang, H.J.7
-
101
-
-
0024513517
-
Flow-cytometric DNA analysis and immunohistochemical measurement of Ki-67 and BUdR labeling indices in human brain tumors
-
Nishizaki T, Orita T, Furutani Y, Ikeyama Y, Aoki H, Sasaki K: Flow-cytometric DNA analysis and immunohistochemical measurement of Ki-67 and BUdR labeling indices in human brain tumors. J Neurosurg 70:379-384, 1989.
-
(1989)
J Neurosurg
, vol.70
, pp. 379-384
-
-
Nishizaki, T.1
Orita, T.2
Furutani, Y.3
Ikeyama, Y.4
Aoki, H.5
Sasaki, K.6
-
102
-
-
0028342664
-
Cloning of senescent-derived inhibitors of DNA synthesis using an expression screen
-
Noda A, Ning Y, Venable SF, Pereira-Smith OM, Smith JR: Cloning of senescent-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211:90-98, 1994.
-
(1994)
Exp Cell Res
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
103
-
-
0027938207
-
Ordering S phase and M phase in the cell cycle
-
Nurse P: Ordering S phase and M phase in the cell cycle. Cell 79:547-550, 1994.
-
(1994)
Cell
, vol.79
, pp. 547-550
-
-
Nurse, P.1
-
106
-
-
0028033270
-
INK4 in human cancer
-
INK4 in human cancer. Proc Natl Acad Sci U S A 91:11045-11049, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11045-11049
-
-
Okamoto, A.1
Demetrick, E.A.2
Spillare, E.A.3
Hagiwara, K.4
Hussain, S.P.5
Bennett, W.P.6
Forrester, B.7
Gerwin, M.8
Serrano, M.9
Beach, D.10
Harris, C.C.11
-
107
-
-
0029878892
-
kip2 in soft tissue sarcomas and Wilms' tumors
-
kip2 in soft tissue sarcomas and Wilms' tumors. Cancer Res 56:1219-1221, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 1219-1221
-
-
Orlow, I.1
Lavarone, A.2
Crider-Miller, S.J.3
Bonilla, F.4
Latres, E.5
Lee, M.H.6
Gerald, W.L.7
Massague, J.8
Weissman, B.E.9
Cordon-Cardo, C.10
-
108
-
-
0028172926
-
Absence of p16 protein is restricted to the subset of lung cancer lines that retains wild-type Rb
-
Otterson GA, Kratzke RA, Coxon A, Kim YW, Kaye FJ: Absence of p16 protein is restricted to the subset of lung cancer lines that retains wild-type Rb. Oncogene 9:3375-3378, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3375-3378
-
-
Otterson, G.A.1
Kratzke, R.A.2
Coxon, A.3
Kim, Y.W.4
Kaye, F.J.5
-
109
-
-
0024473604
-
1 events and regulation of cell proliferation
-
1 events and regulation of cell proliferation. Science 246:603-608, 1989.
-
(1989)
Science
, vol.246
, pp. 603-608
-
-
Pardee, A.B.1
-
112
-
-
0028986931
-
kip1 gene to 12p13 and its analysis in leukemias
-
kip1 gene to 12p13 and its analysis in leukemias. Cancer Res 55:1206-1210, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1206-1210
-
-
Pietenpol, J.A.1
Bohlander, S.K.2
Sato, Y.3
Papadopoulos, N.4
Liu, B.5
Friedman, C.6
Trask, B.J.7
Roberts, J.M.8
Kinzler, K.W.9
Rowley, J.D.10
Vogelstein, B.11
-
113
-
-
0029000579
-
Cyclins and cyclin-dependent kinases: A biochemical view
-
Pines J: Cyclins and cyclin-dependent kinases: A biochemical view. Biochem J 308:697-711, 1995.
-
(1995)
Biochem J
, vol.308
, pp. 697-711
-
-
Pines, J.1
-
114
-
-
0028179669
-
kip1, a cyclin-CDK inhibitor, links transforming growth factor β and contact inhibition to cell cycle arrest
-
kip1, a cyclin-CDK inhibitor, links transforming growth factor β and contact inhibition to cell cycle arrest. Genes Dev 8:9-22, 1994.
-
(1994)
Genes Dev
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.Y.2
Solomon, M.J.3
Sherr, C.J.4
Massague, J.5
Roberts, J.M.6
Koff, A.7
-
115
-
-
0028176483
-
kip1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals
-
kip1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals. Cell 78:59-66, 1994.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
116
-
-
0028986932
-
kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
-
kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 55:1211-1214, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1211-1214
-
-
Ponce-Castaneda, M.V.1
Lee, M.H.2
Latres, E.3
Polyak, K.4
Lacombe, L.5
Montgomery, K.6
Mathew, S.7
Krauter, K.8
Sheinfeld, J.9
Massague, J.10
Cordon-Cardo, C.11
-
117
-
-
0000724804
-
Cell population kinetics in the intestinal epithelium of the mouse
-
Quastler H, Sherman FG: Cell population kinetics in the intestinal epithelium of the mouse. Exp Cell Res 17:420-438, 1959.
-
(1959)
Exp Cell Res
, vol.17
, pp. 420-438
-
-
Quastler, H.1
Sherman, F.G.2
-
119
-
-
0028906986
-
The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor
-
Raffel C, Ueki K, Harsh GR IV, Louis DN: The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor. Neurosurgery 36:971-975, 1995.
-
(1995)
Neurosurgery
, vol.36
, pp. 971-975
-
-
Raffel, C.1
Ueki, K.2
Harsh G.R. IV3
Louis, D.N.4
-
120
-
-
0027978368
-
Amplification of multiple genes from chromosomal region 12q13 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, MDM2
-
Reifenberger G, Reifenberger J, Ichimura K, Meltzer PS, Collins VP: Amplification of multiple genes from chromosomal region 12q13 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, MDM2. Cancer Res 54:4299-4303, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4299-4303
-
-
Reifenberger, G.1
Reifenberger, J.2
Ichimura, K.3
Meltzer, P.S.4
Collins, V.P.5
-
121
-
-
0028173667
-
1/S phase transition by expression of cyclins D1 and e with an inducible system
-
1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol Cell Biol 14:1669-1679, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1669-1679
-
-
Resnitzky, D.1
Gossen, M.2
Bujard, H.3
Reed, S.I.4
-
122
-
-
0014623671
-
The use of tumor growth kinetics in planning "curative" chemotherapy of advanced solid tumors
-
Schabel FM: The use of tumor growth kinetics in planning "curative" chemotherapy of advanced solid tumors. Cancer Res 29:2384-2389, 1969.
-
(1969)
Cancer Res
, vol.29
, pp. 2384-2389
-
-
Schabel, F.M.1
-
123
-
-
0028652269
-
CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
-
Schmidt EE, Ichimura K, Reifenberger G, Collins VP: CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 54:6321-6324, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 6321-6324
-
-
Schmidt, E.E.1
Ichimura, K.2
Reifenberger, G.3
Collins, V.P.4
-
124
-
-
0027769876
-
A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-707, 1994.
-
(1994)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
125
-
-
0029993450
-
Role of the INK4 locus in tumor suppression and cell mortality
-
Serrano M, Lee HW, Chin L, Cordon-Cardo C, Beach D, DePinho RA: Role of the INK4 locus in tumor suppression and cell mortality. Cell 85:27-37, 1996.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.W.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
DePinho, R.A.6
-
126
-
-
0028061670
-
Deregulated expression of E2F-1 induces S phase entry and leads to apoptosis
-
Shan B, Lee WH: Deregulated expression of E2F-1 induces S phase entry and leads to apoptosis. Mol Cell Biol 14:8166-8173, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8166-8173
-
-
Shan, B.1
Lee, W.H.2
-
127
-
-
0027336491
-
1 cyclins
-
1 cyclins. Cell 73:1059-1065, 1993.
-
(1993)
Cell
, vol.73
, pp. 1059-1065
-
-
Sherr, C.J.1
-
128
-
-
0028171292
-
1 phase progression: Cycling on cue
-
1 phase progression: Cycling on cue. Cell 79:551-555, 1994.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
130
-
-
0023571645
-
The use of the monoclonal antibody Ki-67 in determination of the growth fraction in pediatric brain tumors
-
Shibata T, Burger PC: The use of the monoclonal antibody Ki-67 in determination of the growth fraction in pediatric brain tumors. Childs Nerv Syst 2:364-367, 1987.
-
(1987)
Childs Nerv Syst
, vol.2
, pp. 364-367
-
-
Shibata, T.1
Burger, P.C.2
-
131
-
-
0027940495
-
Absence of WAF1 mutations in a variety of human malignancies
-
Shiohara M, El-Deiry WS, Wada M, Nakamaki T, Takeuchi S, Yag R, Chen DL, Vogelstein B, Koeffler HP: Absence of WAF1 mutations in a variety of human malignancies. Blood 84:3781-3784, 1994.
-
(1994)
Blood
, vol.84
, pp. 3781-3784
-
-
Shiohara, M.1
El-Deiry, W.S.2
Wada, M.3
Nakamaki, T.4
Takeuchi, S.5
Yag, R.6
Chen, D.L.7
Vogelstein, B.8
Koeffler, H.P.9
-
132
-
-
0029908550
-
Activity of the retinoblastoma family proteins, pRb, p107, and p130, during cellular proliferation and differentiation
-
Sidle A, Palaty C, Dirks P, Wiggan O, Kiess M, Gill RM, Wong AK, Hamel P: Activity of the retinoblastoma family proteins, pRb, p107, and p130, during cellular proliferation and differentiation. Crit Rev Biochem Mol Biol 31:237-271, 1996.
-
(1996)
Crit Rev Biochem Mol Biol
, vol.31
, pp. 237-271
-
-
Sidle, A.1
Palaty, C.2
Dirks, P.3
Wiggan, O.4
Kiess, M.5
Gill, R.M.6
Wong, A.K.7
Hamel, P.8
-
133
-
-
0024513961
-
The implications of the heterogeneous distribution of Ki-67 labelled cells in meningiomas
-
Siegers HP, Zuber P, Hamou M-F, Van Melle GD, de Tribolet N: The implications of the heterogeneous distribution of Ki-67 labelled cells in meningiomas. Br J Neurosurg 3:101-108, 1989.
-
(1989)
Br J Neurosurg
, vol.3
, pp. 101-108
-
-
Siegers, H.P.1
Zuber, P.2
Hamou, M.-F.3
Van Melle, G.D.4
De Tribolet, N.5
-
134
-
-
0028360766
-
Overexpression of E2F1 in rat embryo fibroblasts leads to neoplastic transformation
-
Singh P, Wong SH, Hong W: Overexpression of E2F1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J 13:3329-3338, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 3329-3338
-
-
Singh, P.1
Wong, S.H.2
Hong, W.3
-
135
-
-
0027587321
-
Activation of the various cyclin/CDC2 protein kinases
-
Solomon MJ: Activation of the various cyclin/CDC2 protein kinases. Curr Opin Cell Biol 5:180-186, 1993.
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 180-186
-
-
Solomon, M.J.1
-
136
-
-
0028879890
-
Homozygous deletion of the MTS1l/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma
-
Sonoda Y, Yoshimoto T, Sekiya T: Homozygous deletion of the MTS1l/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma. Oncogene 11:2145-2149, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 2145-2149
-
-
Sonoda, Y.1
Yoshimoto, T.2
Sekiya, T.3
-
139
-
-
0028929328
-
Mechanisms and genes of cellular suicide
-
Steller H: Mechanisms and genes of cellular suicide. Science 267:1445-1449, 1995.
-
(1995)
Science
, vol.267
, pp. 1445-1449
-
-
Steller, H.1
-
140
-
-
0029069867
-
Qualifying for the license to replicate
-
Su TT, Follette PJ, O'Farrell PH: Qualifying for the license to replicate. Cell 81:825-828, 1995.
-
(1995)
Cell
, vol.81
, pp. 825-828
-
-
Su, T.T.1
Follette, P.J.2
O'Farrell, P.H.3
-
141
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462, 1995.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
142
-
-
0028363519
-
P27, a novel inhibitor of cyclin-CDK protein kinase activity, is related to p21
-
Toyoshima H, Hunter T: p27, a novel inhibitor of cyclin-CDK protein kinase activity, is related to p21. Cell 78:68-74, 1994.
-
(1994)
Cell
, vol.78
, pp. 68-74
-
-
Toyoshima, H.1
Hunter, T.2
-
143
-
-
0030070484
-
CDKN2/p16 or Rb alterations occur in the majority of glioblastomas and are inversely correlated
-
Ueki K, Ono Y, Henson JW, Efird JT, von Deimling A, Louis DN: CDKN2/p16 or Rb alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56:150-153, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 150-153
-
-
Ueki, K.1
Ono, Y.2
Henson, J.W.3
Efird, J.T.4
Von Deimling, A.5
Louis, D.N.6
-
144
-
-
0028897307
-
Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas
-
Walker DG, Duan W, Popovic EA, Kaye AH, Tomlinson FH, Lavin M: Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas. Cancer Res 55:20-23, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 20-23
-
-
Walker, D.G.1
Duan, W.2
Popovic, E.A.3
Kaye, A.H.4
Tomlinson, F.H.5
Lavin, M.6
-
145
-
-
0028243879
-
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
-
Wang TC, Cardiff RD, Zuckerberg L, Lees E, Arnold A, Schmidt EV: Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369:669-671, 1994.
-
(1994)
Nature
, vol.369
, pp. 669-671
-
-
Wang, T.C.1
Cardiff, R.D.2
Zuckerberg, L.3
Lees, E.4
Arnold, A.5
Schmidt, E.V.6
-
146
-
-
0026337295
-
Tumor suppressor genes
-
Weinberg RA: Tumor suppressor genes. Science 254:1138-1146, 1991.
-
(1991)
Science
, vol.254
, pp. 1138-1146
-
-
Weinberg, R.A.1
-
147
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA: The retinoblastoma protein and cell cycle control. Cell 81:323-330, 1995.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
148
-
-
0029977751
-
E2F and cell proliferation: A world turned upside down
-
Weinberg RA: E2F and cell proliferation: A world turned upside down. Cell 85:457-459, 1996.
-
(1996)
Cell
, vol.85
, pp. 457-459
-
-
Weinberg, R.A.1
-
149
-
-
0028136594
-
Cooperative tumorigenic effects of germline mutations in Rb and p53
-
Williams BO, Remington L, Albert DM, Mukai S, Bronson RT, Jacks T: Cooperative tumorigenic effects of germline mutations in Rb and p53. Nat Genet 7:480-484, 1994.
-
(1994)
Nat Genet
, vol.7
, pp. 480-484
-
-
Williams, B.O.1
Remington, L.2
Albert, D.M.3
Mukai, S.4
Bronson, R.T.5
Jacks, T.6
-
150
-
-
0025996773
-
Characterization of a candidate bd-1 gene
-
Withers DA, Harvey RC, Faust JB, Melnyk O, Carey K, Meeker TC: Characterization of a candidate bd-1 gene. Mol Cell Biol 11:4846-4853, 1991.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4846-4853
-
-
Withers, D.A.1
Harvey, R.C.2
Faust, J.B.3
Melnyk, O.4
Carey, K.5
Meeker, T.C.6
-
152
-
-
0029984015
-
Regulating S phase: CDKs, licensing and proteolysis
-
Wuarin J, Nurse P: Regulating S phase: CDKs, licensing and proteolysis. Cell 85:785-787, 1996.
-
(1996)
Cell
, vol.85
, pp. 785-787
-
-
Wuarin, J.1
Nurse, P.2
-
153
-
-
0025824253
-
Human D-type cyclin
-
Xiong Y, Connolly T, Futcher B, Beach D: Human D-type cyclin. Cell 65:691-699, 1991.
-
(1991)
Cell
, vol.65
, pp. 691-699
-
-
Xiong, Y.1
Connolly, T.2
Futcher, B.3
Beach, D.4
-
154
-
-
0027717617
-
P21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D: p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704, 1993.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
155
-
-
0026459047
-
D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
-
Xiong X, Zhang H, Beach D: D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71:505-514, 1992.
-
(1992)
Cell
, vol.71
, pp. 505-514
-
-
Xiong, X.1
Zhang, H.2
Beach, D.3
-
156
-
-
0027301324
-
Subunit arrangement of cyclin-dependent kinases is associated with cellular transformation
-
Xiong Y, Zhang H, Beach D: Subunit arrangement of cyclin-dependent kinases is associated with cellular transformation. Genes Dev 7:1572-1583, 1993.
-
(1993)
Genes Dev
, vol.7
, pp. 1572-1583
-
-
Xiong, Y.1
Zhang, H.2
Beach, D.3
-
157
-
-
0028945789
-
Multiple members of the E2F transcription family are the products of oncogenes
-
Xu G, Livingston DM, Krek W: Multiple members of the E2F transcription family are the products of oncogenes. Proc Natl Acad Sci U S A 92:1357-1361, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 1357-1361
-
-
Xu, G.1
Livingston, D.M.2
Krek, W.3
-
158
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ: Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85:537-548, 1996.
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
Goillot, E.4
Harlow, E.5
Dyson, N.J.6
-
159
-
-
0030053513
-
Mutational analysis of the p16 family cyclin-dependent kinase inhibitors p15 and p18 in tumor-derived cell lines and primary tumors
-
Zariwala M, Liu E, Xiong Y: Mutational analysis of the p16 family cyclin-dependent kinase inhibitors p15 and p18 in tumor-derived cell lines and primary tumors. Oncogene 12:451-455, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 451-455
-
-
Zariwala, M.1
Liu, E.2
Xiong, Y.3
-
160
-
-
0028169236
-
P21 containing cyclin kinases exist in both active and inactive states
-
Zhang H, Hannon GJ, Beach D: p21 containing cyclin kinases exist in both active and inactive states. Genes Dev 8:1750-1758, 1994.
-
(1994)
Genes Dev
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
Hannon, G.J.2
Beach, D.3
-
161
-
-
0028983384
-
Cip1-related domain to bind to cyclin/CDK2 and regulate interactions with E2F
-
Cip1-related domain to bind to cyclin/CDK2 and regulate interactions with E2F. Genes Dev 9:1740-1752, 1995.
-
(1995)
Genes Dev
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
-
162
-
-
0023839245
-
Identification of proliferating cells in human gliomas using the monoclonal antibody Ki-67
-
Zuber P, Hamou M-F, de Tribolet N: Identification of proliferating cells in human gliomas using the monoclonal antibody Ki-67. Neurosurgery 22:364-368, 1988.
-
(1988)
Neurosurgery
, vol.22
, pp. 364-368
-
-
Zuber, P.1
Hamou, M.-F.2
De Tribolet, N.3
|