메뉴 건너뛰기




Volumn 82, Issue 4, 1995, Pages 675-684

Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Author keywords

[No Author keywords available]

Indexed keywords

CIP1 PROTEIN; CYCLINE; DNA; PROTEIN P53; CYCLIN DEPENDENT KINASE; PROTEIN P21; TRANSFERASE INHIBITOR;

EID: 0028978183     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90039-X     Document Type: Article
Times cited : (1968)

References (64)
  • 1
    • 0028946766 scopus 로고
    • Accumulation of wild-type p53 protein upon γ-irradiation induces a G2 arrestdependent immunoglobulin λ light chain gene expression
    • (1995) EMBO J. , vol.14 , pp. 1392-1401
    • Aloni-Grinstein1    Schwartz2    Rotter3
  • 5
    • 0029315510 scopus 로고
    • Tumor suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage
    • (1995) Bioessays , vol.17 , pp. 501-508
    • Cox1    Lane2
  • 16
    • 0026713875 scopus 로고
    • Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15
    • (1992) EMBO J. , vol.11 , pp. 3995-4005
    • Gu1    Rosenblatt2    Morgan3
  • 17
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • (1993) Nature , vol.366 , pp. 707-710
    • Gu1    Turck2    Morgan3
  • 19
    • 0026452949 scopus 로고
    • Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
    • (1992) Cell , vol.71 , pp. 543-546
    • Hartwell1
  • 21
  • 34
    • 0027283604 scopus 로고
    • Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents
    • (1993) Blood , vol.82 , pp. 1092-1096
    • Lotem1    Sachs2
  • 37
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 tumor antigen in non-transformed mouse cells
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1689-1694
    • Maitzman1    Czyzk2
  • 39
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita1    Reed2
  • 43
    • 0027944251 scopus 로고
    • Cyclin G is a transcriptional target of the tumor suppressor protein p53
    • (1994) EMBO J. , vol.13 , pp. 4816-4923
    • Okamoto1    Beach2
  • 48
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr1    Roberts2
  • 53
    • 0027461627 scopus 로고
    • Eubcl2 transgene facilitates spontaneaous transformation of early pre-B and Ig secreting cells but not T cells
    • (1993) Oncogene , vol.8 , pp. 1-9
    • Strasser1    Harris2    Cory3
  • 54
    • 0016242582 scopus 로고
    • N-(hosphonacetyl)l-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture
    • (1974) J. Biol. Chem. , vol.249 , pp. 6945-6950
    • Swyryd1    Seaver2    Stark3
  • 55
  • 56
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima1    Hunter2
  • 58
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interacting with PCNA
    • (1994) Nature , vol.369 , pp. 574-578
    • Wage1    Hannon2    Beach3    Stillman4
  • 59
    • 0018787266 scopus 로고
    • Gene amplification causes overproduction of the first three enzymes of UMP in N-(phosphonacetyl)-l-aspartate resistant hamster cells
    • (1979) J. Biol. Chem. , vol.254 , pp. 8679-8689
    • Wahl1    Padgett2    Stark3
  • 64
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin1    Tainsky2    Bischoff3    Strong4    Wahl5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.