A new approach to docking in the β2-adrenergic receptor that exploits the domain structure of G-protein-coupled receptors

Journal of Medicinal Chemistry

Volumn 40, Issue 24, 1997, Pages 3871-3886

  Gouldson, Paul R ^a   Snell, Christopher R ^b   Reynolds, Christopher A ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b Novatis Inst for Medical Sciences   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; NORADRENALIN; PINDOLOL; PROPRANOLOL DERIVATIVE; RHODOPSIN;

ARTICLE; BINDING AFFINITY; COMPUTER SIMULATION; HYDROPHOBICITY; LIGAND BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; GTP-BINDING PROTEINS; MEMBRANE PROTEINS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030831364     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960647n     Document Type: Article

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