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Volumn 22, Issue 9, 1997, Pages 987-993

Pegylated recombinant megakaryocyte growth and development factor. Hematopoietic

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CYCLOPHOSPHAMIDE; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; PACLITAXEL; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR;

EID: 0030781318     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.1997.022.09.421884     Document Type: Review
Times cited : (3)

References (60)
  • 2
    • 0021994152 scopus 로고
    • Purification and partial characterization of a megakaryocyte colony-stimulating factor from human plasma
    • Hoffman, R., Yang, H.H., Bruno, E., Straneva, J.E. Purification and partial characterization of a megakaryocyte colony-stimulating factor from human plasma. J Clin Invest 1985, 75: 1174-82.
    • (1985) J Clin Invest , vol.75 , pp. 1174-1182
    • Hoffman, R.1    Yang, H.H.2    Bruno, E.3    Straneva, J.E.4
  • 3
    • 0022624954 scopus 로고
    • MPLV: A retro-virus complex inducing an acute myeloproliferative leukemia disorder in adult mice
    • Wendling, F., Varlet, P., Charon, M., Tambourin, P. MPLV: A retro-virus complex inducing an acute myeloproliferative leukemia disorder in adult mice. Virology 1986, 149: 242-6.
    • (1986) Virology , vol.149 , pp. 242-246
    • Wendling, F.1    Varlet, P.2    Charon, M.3    Tambourin, P.4
  • 4
    • 0025674093 scopus 로고
    • A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors
    • Souyri, M., Vigon, I., Penciolelli, J.F., Heard, J.M., Tambourin, P., Wendung, F. A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 1990, 63: 1137-47.
    • (1990) Cell , vol.63 , pp. 1137-1147
    • Souyri, M.1    Vigon, I.2    Penciolelli, J.F.3    Heard, J.M.4    Tambourin, P.5    Wendung, F.6
  • 5
    • 0026684707 scopus 로고
    • Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily
    • Vigon, I., Mornon, J.P., Cocault, L., Mitjavila, M.T., Tambourin, P., Gisselbrecht, S., Souyri, M. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily. Proc Natl Acad Sci USA 1992, 89: 5640-4.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5640-5644
    • Vigon, I.1    Mornon, J.P.2    Cocault, L.3    Mitjavila, M.T.4    Tambourin, P.5    Gisselbrecht, S.6    Souyri, M.7
  • 6
    • 0027225872 scopus 로고
    • Oligodeoxynucleotides antisense to the protooncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis
    • Methia, N., Louache, F., Vainchenker, W., Wendling, F. Oligodeoxynucleotides antisense to the protooncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood 1993, 82: 1395-401.
    • (1993) Blood , vol.82 , pp. 1395-1401
    • Methia, N.1    Louache, F.2    Vainchenker, W.3    Wendling, F.4
  • 7
    • 0028985426 scopus 로고
    • The Mpl receptor is expressed in megakaryocytic lineage from late progenitors to platelets
    • Debili, N., Wendling, F., Cosman, D. et al. The Mpl receptor is expressed in megakaryocytic lineage from late progenitors to platelets. Blood 1995, 85: 391-401.
    • (1995) Blood , vol.85 , pp. 391-401
    • Debili, N.1    Wendling, F.2    Cosman, D.3
  • 8
    • 0028302409 scopus 로고
    • Stimulation of megakaryopoiesis and thrombopoiesis by the c-mpl ligand
    • de Sauvage, F.J., Hass, P.E., Spencer, S.D. et al. Stimulation of megakaryopoiesis and thrombopoiesis by the c-mpl ligand. Nature 1994, 369: 533-8.
    • (1994) Nature , vol.369 , pp. 533-538
    • De Sauvage, F.J.1    Hass, P.E.2    Spencer, S.D.3
  • 9
    • 0028343099 scopus 로고
    • Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor mpl
    • Bartley, T.D., Bogenberger, J., Hunt, P. et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor mpl. Cell 1994, 77: 1117-24.
    • (1994) Cell , vol.77 , pp. 1117-1124
    • Bartley, T.D.1    Bogenberger, J.2    Hunt, P.3
  • 10
    • 0028199208 scopus 로고
    • Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
    • Lok, S., Kaushansky, K., Holly, R.D. et al. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 1994, 369: 565-8.
    • (1994) Nature , vol.369 , pp. 565-568
    • Lok, S.1    Kaushansky, K.2    Holly, R.D.3
  • 11
    • 0028117771 scopus 로고
    • The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production
    • Kuter, D.J., Beeler, D.L., Rosenberg, R.D. The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci USA 1994, 91: 11104-8.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11104-11108
    • Kuter, D.J.1    Beeler, D.L.2    Rosenberg, R.D.3
  • 12
    • 0029148579 scopus 로고
    • Purification and characterization of thrombopoietin
    • Tokyo
    • Kato, T., Ogami, K., Shimada, Y. et al. Purification and characterization of thrombopoietin. J Biochem (Tokyo) 1995, 118: 229-36.
    • (1995) J Biochem , vol.118 , pp. 229-236
    • Kato, T.1    Ogami, K.2    Shimada, Y.3
  • 13
    • 0028898571 scopus 로고
    • Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene
    • Chang, M.D., McNinch, J., Basu, R. et al. Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene. J Biol Chem 1995, 270: 511-4.
    • (1995) J Biol Chem , vol.270 , pp. 511-514
    • Chang, M.D.1    McNinch, J.2    Basu, R.3
  • 14
    • 0028899548 scopus 로고
    • Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin
    • Gurney, A.L., Kuang, W.-J., Xie, M.-H., Malloy, B.E., Eaton, D.L., de Sauvage, F.L. Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin. Blood 1995, 85: 981-8.
    • (1995) Blood , vol.85 , pp. 981-988
    • Gurney, A.L.1    Kuang, W.-J.2    Xie, M.-H.3    Malloy, B.E.4    Eaton, D.L.5    De Sauvage, F.L.6
  • 15
    • 0029051730 scopus 로고
    • Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice
    • Ulich, T.R., Del Castillo, J., Yin, S. et al. Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice. Blood 1995, 86: 971-6.
    • (1995) Blood , vol.86 , pp. 971-976
    • Ulich, T.R.1    Del Castillo, J.2    Yin, S.3
  • 16
    • 0028803099 scopus 로고
    • Pegylated megakaryocyte growth and development factor abrogates the lethal thrombocytopenia associated with carboplatin and irradiation in mice
    • Hokom, M.M., Lacey, D., Kinstler, O.B. et al. Pegylated megakaryocyte growth and development factor abrogates the lethal thrombocytopenia associated with carboplatin and irradiation in mice. Blood 1995, 86: 4486-92.
    • (1995) Blood , vol.86 , pp. 4486-4492
    • Hokom, M.M.1    Lacey, D.2    Kinstler, O.B.3
  • 17
    • 0028332474 scopus 로고
    • Promotion of megakaryocyte progenitor expansion and differentiation by the c-mpl ligand thrombopoietin
    • Kaushansky, K., Lok, S., Holly, R.D. et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-mpl ligand thrombopoietin. Nature 1994, 369: 568-71.
    • (1994) Nature , vol.369 , pp. 568-571
    • Kaushansky, K.1    Lok, S.2    Holly, R.D.3
  • 19
    • 0028909690 scopus 로고
    • Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro
    • Broudy, V.C., Lin, N.L., Kaushansky, K. Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 1995, 85: 1719-26.
    • (1995) Blood , vol.85 , pp. 1719-1726
    • Broudy, V.C.1    Lin, N.L.2    Kaushansky, K.3
  • 20
    • 0029977501 scopus 로고    scopus 로고
    • Differential cytokine effects on primitive (CD34+ CD38-) human hematopoietic cells: Novel responses to Flt3-ligand and thrombopoietin
    • Petzer, A.L., Zandstra, P.W., Piret, J.M., Eaves, C.J. Differential cytokine effects on primitive (CD34+ CD38-) human hematopoietic cells: Novel responses to Flt3-ligand and thrombopoietin. J Exp Med 1996, 183: 2551-8.
    • (1996) J Exp Med , vol.183 , pp. 2551-2558
    • Petzer, A.L.1    Zandstra, P.W.2    Piret, J.M.3    Eaves, C.J.4
  • 22
    • 0029027918 scopus 로고
    • Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors
    • Kobayashi, M., Laver, J.H., Kato, T., Miyazaki, H., Ogawa, M. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood 1995, 86: 2494-9.
    • (1995) Blood , vol.86 , pp. 2494-2499
    • Kobayashi, M.1    Laver, J.H.2    Kato, T.3    Miyazaki, H.4    Ogawa, M.5
  • 23
    • 0030968519 scopus 로고    scopus 로고
    • Human platelets display high-affinity receptors for thrombopoietin
    • Broudy, V.C., Lin, N.L., Sabath, D.F. Human platelets display high-affinity receptors for thrombopoietin. Blood 1997, 89: 1896-904.
    • (1997) Blood , vol.89 , pp. 1896-1904
    • Broudy, V.C.1    Lin, N.L.2    Sabath, D.F.3
  • 24
    • 0029037953 scopus 로고
    • The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors
    • Debili, N., Wendling, F., Katz, A., Guichard, J., Breton-Gorius, J., Hunt, P., Vainchenker, W. The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood 1995, 86: 2516-25.
    • (1995) Blood , vol.86 , pp. 2516-2525
    • Debili, N.1    Wendling, F.2    Katz, A.3    Guichard, J.4    Breton-Gorius, J.5    Hunt, P.6    Vainchenker, W.7
  • 25
    • 0024450006 scopus 로고
    • The effect of partially purified thrombopoietin on guinea pig megakaryocyte ploidy in vitro
    • Hill, R.J., Leven, R.M., Levin, F.C., Levin, J. The effect of partially purified thrombopoietin on guinea pig megakaryocyte ploidy in vitro. Exp Hematol 1989, 17: 903-7.
    • (1989) Exp Hematol , vol.17 , pp. 903-907
    • Hill, R.J.1    Leven, R.M.2    Levin, F.C.3    Levin, J.4
  • 27
    • 0029837329 scopus 로고    scopus 로고
    • Effect of thrombopoietin on the development of megakaryocytes and platelets: An ultrastructural analysis
    • Zucker-Franklin, D., Kaushansky, K. Effect of thrombopoietin on the development of megakaryocytes and platelets: An ultrastructural analysis. Blood 1996, 88: 1632-8.
    • (1996) Blood , vol.88 , pp. 1632-1638
    • Zucker-Franklin, D.1    Kaushansky, K.2
  • 28
    • 0029794750 scopus 로고    scopus 로고
    • Thrombopoietin stimulates colony-forming unit megakaryocyte proliferation and megakaryocyte maturation independently of cytokines that signal through the gp130 receptor subunit
    • Broudy, V.C., Lin, N.L., Fox, N., Taga, T., Saito, M., Kaushansky, K. Thrombopoietin stimulates colony-forming unit megakaryocyte proliferation and megakaryocyte maturation independently of cytokines that signal through the gp130 receptor subunit. Blood 1996, 88: 2026-32.
    • (1996) Blood , vol.88 , pp. 2026-2032
    • Broudy, V.C.1    Lin, N.L.2    Fox, N.3    Taga, T.4    Saito, M.5    Kaushansky, K.6
  • 29
    • 0029022246 scopus 로고
    • Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro
    • Choi, E.S., Hokom, M., Bartley, T. et al. Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro. Stem Cells 1995, 13: 317-22.
    • (1995) Stem Cells , vol.13 , pp. 317-322
    • Choi, E.S.1    Hokom, M.2    Bartley, T.3
  • 31
    • 0031057949 scopus 로고    scopus 로고
    • Action of thrombopoietin at the megakaryocyte progenitor level is critical for the subsequent proplatelet production
    • Horie, K., Miyazaki, H., Hagiwara, T., Tahara, E., Matsumoto, A., Kadoya, T., Ogami, K., Kato, T. Action of thrombopoietin at the megakaryocyte progenitor level is critical for the subsequent proplatelet production. Exp Hematol 1997, 25: 169-76.
    • (1997) Exp Hematol , vol.25 , pp. 169-176
    • Horie, K.1    Miyazaki, H.2    Hagiwara, T.3    Tahara, E.4    Matsumoto, A.5    Kadoya, T.6    Ogami, K.7    Kato, T.8
  • 34
    • 0029960265 scopus 로고    scopus 로고
    • Deficiencies in progenitor cells of multiple hemopoietic lineages and defective megakaryopoiesis in mice lacking the thrombopoietin receptor c-mpl
    • Alexander, W.S., Roberts, A.W., Nicola, N.A., Li, R., Metcalf, D. Deficiencies in progenitor cells of multiple hemopoietic lineages and defective megakaryopoiesis in mice lacking the thrombopoietin receptor c-mpl. Blood 1996, 87: 2162-70.
    • (1996) Blood , vol.87 , pp. 2162-2170
    • Alexander, W.S.1    Roberts, A.W.2    Nicola, N.A.3    Li, R.4    Metcalf, D.5
  • 36
    • 0028022980 scopus 로고
    • Appearance of a megakaryocyte growth-promoting activity, megapoietin, during acute thrombocytopenia in the rabbit
    • Kuter, D.J., Rosenberg, R.D. Appearance of a megakaryocyte growth-promoting activity, megapoietin, during acute thrombocytopenia in the rabbit. Blood 1994, 84: 1464-72.
    • (1994) Blood , vol.84 , pp. 1464-1472
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 38
    • 0029030356 scopus 로고
    • The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit
    • Kuter, D.J., Rosenberg, R.D. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood 1995, 85: 2720-30.
    • (1995) Blood , vol.85 , pp. 2720-2730
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 39
    • 0029046966 scopus 로고
    • Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia
    • Nichol, J.L., Hokom, M.M., Hornkohl, A. et al. Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia. J Clin Invest 1995, 95: 2973-8.
    • (1995) J Clin Invest , vol.95 , pp. 2973-2978
    • Nichol, J.L.1    Hokom, M.M.2    Hornkohl, A.3
  • 40
    • 0029062371 scopus 로고
    • Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates
    • Farese, A.M., Hunt, P., Boone, T., MacVittie, T.J. Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates. Blood 1995, 86: 54-9.
    • (1995) Blood , vol.86 , pp. 54-59
    • Farese, A.M.1    Hunt, P.2    Boone, T.3    MacVittie, T.J.4
  • 41
    • 0030068687 scopus 로고    scopus 로고
    • Regulation of platelet production and function by megakaryocyte growth and development factor (MGDF) in nonhuman primates
    • Harker, L.A., Hunt, P., Marzec, U.M., Kelly, A.B., Tomer, A., Hanson, S.R., Stead, R.B. Regulation of platelet production and function by megakaryocyte growth and development factor (MGDF) in nonhuman primates. Blood 1996, 87: 1833-44.
    • (1996) Blood , vol.87 , pp. 1833-1844
    • Harker, L.A.1    Hunt, P.2    Marzec, U.M.3    Kelly, A.B.4    Tomer, A.5    Hanson, S.R.6    Stead, R.B.7
  • 42
    • 0029943307 scopus 로고    scopus 로고
    • Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates
    • Harker, L.A., Marzec, U.M., Hunt, P., Kelly, A.B., Tomer, A., Cheung, E., Hanson, S.R., Stead, R.B. Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates. Blood 1996, 88: 511-21.
    • (1996) Blood , vol.88 , pp. 511-521
    • Harker, L.A.1    Marzec, U.M.2    Hunt, P.3    Kelly, A.B.4    Tomer, A.5    Cheung, E.6    Hanson, S.R.7    Stead, R.B.8
  • 43
    • 0029963122 scopus 로고    scopus 로고
    • Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia
    • Farese, A.M., Hunt, P., Grab, L.B., MacVittie, T.J. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia. J Clin Invest 1996, 97: 2145-51.
    • (1996) J Clin Invest , vol.97 , pp. 2145-2151
    • Farese, A.M.1    Hunt, P.2    Grab, L.B.3    MacVittie, T.J.4
  • 44
    • 0031019748 scopus 로고    scopus 로고
    • Prevention of thrombocytopenia and neutropenia in a nonhuman primate model of marrow suppressive chemotherapy by combining pegylated recombinant human megakaryocyte growth and development factor and recombinant human granulocyte colony-stimulating factor
    • Harker, L.A., Marzec, U.M., Kelly, A.B., Cheung, E., Tomer, A., Nichol, J.L., Hanson, S.R., Stead, R.B. Prevention of thrombocytopenia and neutropenia in a nonhuman primate model of marrow suppressive chemotherapy by combining pegylated recombinant human megakaryocyte growth and development factor and recombinant human granulocyte colony-stimulating factor. Blood 1997, 89: 155-65.
    • (1997) Blood , vol.89 , pp. 155-165
    • Harker, L.A.1    Marzec, U.M.2    Kelly, A.B.3    Cheung, E.4    Tomer, A.5    Nichol, J.L.6    Hanson, S.R.7    Stead, R.B.8
  • 45
    • 0029999474 scopus 로고    scopus 로고
    • Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients
    • Molineux, G., Hartley, C., McElroy, P., McCrea, C., McNiece, I.K. Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients. Blood 1996, 88: 366-76.
    • (1996) Blood , vol.88 , pp. 366-376
    • Molineux, G.1    Hartley, C.2    McElroy, P.3    McCrea, C.4    McNiece, I.K.5
  • 46
    • 0029080417 scopus 로고
    • Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation
    • Toombs, C.F., Young, C.H., Glaspy, J.A., Varnum, B.C. Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation. Thromb Res 1995, 80: 23-33.
    • (1995) Thromb Res , vol.80 , pp. 23-33
    • Toombs, C.F.1    Young, C.H.2    Glaspy, J.A.3    Varnum, B.C.4
  • 47
    • 0029912139 scopus 로고    scopus 로고
    • Effects of recombinant human megakaryocyte growth and development factor on platelet activation
    • Montrucchio, G., Brizzi, M.F., Calosso, G., Marengo, S., Pegoraro, L., Camussi, G. Effects of recombinant human megakaryocyte growth and development factor on platelet activation. Blood 1996, 87: 2762-8.
    • (1996) Blood , vol.87 , pp. 2762-2768
    • Montrucchio, G.1    Brizzi, M.F.2    Calosso, G.3    Marengo, S.4    Pegoraro, L.5    Camussi, G.6
  • 48
    • 0029979883 scopus 로고    scopus 로고
    • Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation
    • Rodríguez-Liñares, B., Watson, S.P. Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation. Biochem J 1996, 316: 93-8.
    • (1996) Biochem J , vol.316 , pp. 93-98
    • Rodríguez-Liñares, B.1    Watson, S.P.2
  • 49
    • 9444287622 scopus 로고    scopus 로고
    • Thrombopoietin modulates platelet activation in vitro through protein-tyrosine phosphorylation
    • Kubota, Y., Arai, T., Tanaka, T. et al. Thrombopoietin modulates platelet activation in vitro through protein-tyrosine phosphorylation. Stem Cells 1996, 14: 439-44.
    • (1996) Stem Cells , vol.14 , pp. 439-444
    • Kubota, Y.1    Arai, T.2    Tanaka, T.3
  • 50
    • 9344225757 scopus 로고    scopus 로고
    • Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists
    • Oda, A., Miyakawa, Y., Druker, B.J. et al. Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists. Blood 1996, 87: 4664-70.
    • (1996) Blood , vol.87 , pp. 4664-4670
    • Oda, A.1    Miyakawa, Y.2    Druker, B.J.3
  • 51
    • 0028843848 scopus 로고
    • Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice
    • Yan, X.Q., Lacey, D., Fletcher, F. et al. Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice. Blood 1995, 86: 4025-33.
    • (1995) Blood , vol.86 , pp. 4025-4033
    • Yan, X.Q.1    Lacey, D.2    Fletcher, F.3
  • 52
    • 0031020240 scopus 로고    scopus 로고
    • Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or antiplatelet serum treatment
    • Zhou, W., Toombs, C.F., Zou, T., Guo, J., Robinson, M.O. Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or antiplatelet serum treatment. Blood 1997, 89: 1551-9.
    • (1997) Blood , vol.89 , pp. 1551-1559
    • Zhou, W.1    Toombs, C.F.2    Zou, T.3    Guo, J.4    Robinson, M.O.5
  • 53
    • 0031035555 scopus 로고    scopus 로고
    • Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization
    • Sungaran, R., Markovic, B., Chong, B.H. Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood 1997, 89: 101-7.
    • (1997) Blood , vol.89 , pp. 101-107
    • Sungaran, R.1    Markovic, B.2    Chong, B.H.3
  • 54
    • 1842295187 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of pegylated recombinant human megakaryocyte growth and development factor in humans
    • submitted
    • de Boer, R.H., Roskos, L.K., Cheung, E., Fox, S., Basser, R.L., Marty, J. et al. Pharmacokinetic analysis of pegylated recombinant human megakaryocyte growth and development factor in humans. Blood 1997, submitted.
    • (1997) Blood
    • De Boer, R.H.1    Roskos, L.K.2    Cheung, E.3    Fox, S.4    Basser, R.L.5    Marty, J.6
  • 55
    • 10344235968 scopus 로고    scopus 로고
    • Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer
    • Basser, R.L, Rasko, J.E.J., Clarke, K. et al. Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet 1996, 348: 1279-81.
    • (1996) Lancet , vol.348 , pp. 1279-1281
    • Basser, R.L.1    Rasko, J.E.J.2    Clarke, K.3
  • 56
    • 8544258752 scopus 로고    scopus 로고
    • Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF
    • Rasko, J.E.J., Basser, R.L., Boyd, J. et al. Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF. Brit J Haematol 1997, 97: 871-80.
    • (1997) Brit J Haematol , vol.97 , pp. 871-880
    • Rasko, J.E.J.1    Basser, R.L.2    Boyd, J.3
  • 57
    • 10344238601 scopus 로고    scopus 로고
    • Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation
    • O'Malley, C.J., Rasko, J.E.J., Basser, R.L. et al. Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation. Blood 1996, 88: 3288-98.
    • (1996) Blood , vol.88 , pp. 3288-3298
    • O'Malley, C.J.1    Rasko, J.E.J.2    Basser, R.L.3
  • 58
    • 17944389931 scopus 로고    scopus 로고
    • Randomised, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) with filgrastim after dose-intensive chemotherapy in patients with advanced cancer
    • Basser, R.L., Rasko, J.E.J., Clarke, K. et al. Randomised, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) with filgrastim after dose-intensive chemotherapy in patients with advanced cancer. Blood 1997, 89: 3118-28.
    • (1997) Blood , vol.89 , pp. 3118-3128
    • Basser, R.L.1    Rasko, J.E.J.2    Clarke, K.3
  • 59
    • 0024359117 scopus 로고
    • Treatment of chemotherapy-induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and duration of therapy
    • Morstyn, G., Campbell, L., Lieschke, G. et al. Treatment of chemotherapy-induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and duration of therapy. J Clin Oncol 1989, 7: 1554-62.
    • (1989) J Clin Oncol , vol.7 , pp. 1554-1562
    • Morstyn, G.1    Campbell, L.2    Lieschke, G.3
  • 60
    • 0031049879 scopus 로고    scopus 로고
    • Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer
    • Fanucchi, M., Glaspy, J., Crawford, J., Garst, J., Figlin, R., Sheridan, W., Menchaca, D., Tomita, Ozer, H., Harker, L. Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer. New Engl J Med 1997, 336: 404-9.
    • (1997) New Engl J Med , vol.336 , pp. 404-409
    • Fanucchi, M.1    Glaspy, J.2    Crawford, J.3    Garst, J.4    Figlin, R.5    Sheridan, W.6    Menchaca, D.7    Tomita8    Ozer, H.9    Harker, L.10


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