Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium

Journal of the American College of Cardiology

Volumn 27, Issue 5, 1996, Pages 1286-1291

  Ichikawa, Ken Ichiro ^a   Hidai, Chiaki ^a,b   Okuda, Chikako ^a   Kimata, Shin Ichi ^a   Matsuoka, Rumiko ^a   Hosoda, Saichi ^a   Quertermous, Thomas ^b   Kawana, Masatoshi ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; MONOCROTALINE; MYOSIN HEAVY CHAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029871898     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0735-1097(95)00568-4     Document Type: Article

References (39)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-5.
2. Masaki T, Kimura S, Yanagisawa M, Goto K. Molecular and cellular mechanism of endothelin regulation. Implications for vascular function [review]. Circulation 1991;84:1457-68.
3. Hilkert R, Lee M, Quertermous T. Genetic regulation of endothelin-1 in vascular endothelial cells. Trends Cardiovasc Med 1992;2:129-33.
4. Ishikawa T, Yanagisawa M, Kimura H, Goto K, Masaki T. Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol 1988;255:H970-3.
5. Suzuki T, Hoshi H, Mitsui Y. Endothelin stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium. FEBS Lett 1990;268:149-51.
6. Shubeita HE, McDonough PM, Harris AN, et al. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. J Biol Chem 1990;265:20555-62,
7. Ito H, Hirata Y, Hiroe M, et al. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res 1991;69:209-15.
8. Wang DL, Chen JJ, Shin NL, et al. Endothelin stimulates cardiac alpha- and beta- myosin heavy chain gene expression. Biochem Biophys Res Commun 1992;183:1260-5.
9. Ito H, Hirata Y, Adachi S, et al. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993;92:398-403.
10. Schwartz K, Boheler KR, de la Bastie D, Lompre AM, Mercadier JJ. Switches in cardiac muscle gene expression as a result of pressure and volume overload [review]. Am J Physiol 1992;262:R364-9.
11. Morkin E. Regulation of myosin heavy chain genes in the heart [review]. Circulation 1993;87:1451-60.
12. Izumo S, Lompre AM, Matsuoka R, et al. Myosin heavy chain messenger RNA and protein isoform transition during cardiac hypertrophy. J Clin Invest 1987;79:970-7.
13. Imamura S, Matsuoka R, Hiratsuka E, et al. Adaptational changes of MHC gene expression and isozyme transition in cardiac overloading. Am J Physiol 1991;260:H73-9.
14. Chassagne C, Wisnewsky C, Schwartz K. Antithetical accumulation of myosin heavy chain but not alpha-actin mRNA isoforms during early stages of pressure-overload-induced rat cardiac hypertrophy. Circ Res 1993;72:857-64.
15. Meyrick B, Gamble W, Reid L. Development of Crotalaria pulmonary hypertension: hemodynamic and structural study. Am J Physiol 1980;239: H692-702.
16. Ghodsi F, Will JA. Changes in pulmonary structure and function induced by monocrotaline intoxication. Am J Physiol 1981;240:H149-55.
17. Bruner LH, Hilliker KS, Roth RA. Pulmonary hypertension and ECG changes from monocrotaline pyrrole in the rat. Am J Physiol H300-6.
18. Wilson DW, Segall HJ, Pan LC, Lame MW, Estep JE, Morin D. Mechanisms and pathology of monocrotaline pulmonary toxicity [review]. Crit Rev Toxicol 1992;22:307-25.
19. Sogabe K, Nirei H, Shoubo M, et al. Pharmacological profile of FR139317, a novel, potent endothelin ETA receptor antagonist. J Pharmacol Exp Ther 1993;262:1040-6.
20. Suzuki N, Matsumoto H, Kitada C, Masaki T, Fujino M. A sensitive sandwich-enzyme immunoassay for human endothelin. J Immunol Methods 1989;118:245-50.
21. Hoh JFY, McGrath PA, Hale HT, Electrophoretic analysis of multiple forms of rat cardiac myosin. Effect of hypophysectomy and thyroxine replacement. J Mol Cell Cardiol 1978;10:1053-76.
22. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-9.
23. Mahdavi V, Izumo S, Nadal GB. Developmental and hormonal regulation of sarcomeric myosin heavy chain gene family. Circ Res 1987;60:804-14.
24. Zar JH. Biostatistical Analysis. 2nd ed. Englewood Cliffs (NJ): Prentice-Hall, 1984:239-41.
25. Miyauchi T, Yorikane R, Sakai S, et al. Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension. Circ Res 1993;73:887-97.
26. Ito H, Hiroe M, Hirata Y, et al. Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload. Circulation 1994; 89:2198-203.
27. Hirata Y, Takagi Y, Fukuda Y, Marumo F. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis 1989;78:225-8.
28. Sadoshima J, Izumo S. Signal transduction pathways of angiotensin II-induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers. Circ Res 1993;73:424-38.
29. Komuro I, Katoh Y, Kaida T, et al. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation. J Biol Chem 1991;266:1265-8.
30. Yamazaki T, Tobe K, Hoh E, et al. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J Biol Chem 1993;268:12069-76.
31. Sadoshima J, Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J 1993;12:1681-92.
32. Sadoshima J, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993;75:977-84.
33. Waspe LE, Ordahl CP, Simpson PC. The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes. J Clin Invest 1990;85:1206-14.
34. Kariya K, Karns LR, Simpson PC. Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene. J Biol Chem 1991;266:10023-6.
35. Kariya K, Karns LR, Simpson PC. An enhancer core element mediates stimulation of the rat beta-myosin heavy chain promoter by an alpha 1-adrenergic agonist and activated beta-protein kinase C in hypertrophy of cardiac myocytes. J Biol Chem 1994;269:3775-82.
36. Dzau VJ, Pratt RE. Cardiac, vascular and intrarenal renin angiotensin system in normal physiology and disease. In: Robertson JIS, Nicholls MG, editors. In the Renin-Angiotensin System. London: Gower Medical Publishing, 1993:42.1-42.8.
37. Pfeffer MA, Lamas GA, Vaughan DE, Parisi AF, Braunwald E. Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction. N Engl J Med 1988;319:80-6.
38. Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992;327:669-77.
39. Dickstein K, Gottlieb S, Reck E, et al. Hemodynamic and neurohumoral effects of the angiotensin II antagonist losartan in patients with heart failure. J Hypertension 1994;12 Suppl:S31-S35.