G protein coupled receptors as modules of interacting proteins: A family meeting

Progress in Drug Research

Volumn 49, Issue , 1997, Pages 173-218

  Valdenaire, Olivier ^a   Vernier, Philippe ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

CONFORMATIONAL TRANSITION; COUPLING FACTOR; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; EFFECTOR CELL; ENZYME SPECIFICITY; LIGAND BINDING; MOLECULAR INTERACTION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTO ONCOGENE; RECEPTOR AFFINITY; REVIEW; RNA TRANSLATION;

EID: 0030737014     PISSN: 0071786X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-0348-8863-9_6     Document Type: Review

References (225)

1. Abeijon, C. and Hirschberg, C.: Trends Biochem Sci 17, 32-36 (1992).
2. Almaula, N., Ebersole, B., Zhang, D., Weinstein, H. and Sealfon, S.: J Biol Chem 271, 14672-14675 (1996).
3. Applebury, M. and Hargrave, P: Vision Res 26, 1881-95 (1986).
4. Arai, H., Hori, S., Aramori, I., Ohkubo, H. and Nakanishi, S.: Nature 348, 730-2 (1990).
5. Arora, K., Sakai, A. and Catt, K.: J Biol Chem 270, 22820-22826 (1995).
6. Arriza, J., Dawson, T., Simerly, R., Martin, L., Caron, M., Snyder, S. and Lefkowitz, R.: J Neurosci 12, 4045-4055 (1992).
7. Attramadal, H., Arriza, J., Aoki, C., Dawson, T., Codina, J., Kwatra, M., Snyder, S., Caron, M. and Lefkowitz, R.: J Biol Chem 267, 17882-17890 (1992).
8. Audigier, Y., Friedlander, M. and Blobel, G.: Proc Natl Acad Sci USA 84, 5783-5787 (1987).
9. Avigan, J., Murtagh, J. J., Stevens, L., Angus, C., Moss, J. and Vaughan, M.: Biochemistry 31, 7736-7740 (1992).
10. Barak, L.,Tiberi, M., Freedman, N., Kwatra, M., Lefkowitz, R. and Caron, M.: J Biol Chem 269, 2790-2795 (1994).
11. Barr, F.A., Leyte, A. and Huttner, W.B.: Trends Cell Biol 2, 91-94 (1992).
12. Bates, M., Senogles, S., Bunzow, J., Liggett, S., Civelli, O. and Caron, M.: Mol Pharmacol 39, 55-63 (1991).
13. Beltzer, J., Fiedler, K., Fuhrer, C., Geffen, I., Handschin, C., Wessels, H. and Spiess, M.: J Biol Chem 266, 973-978 (1991).
14. Benya, R., Fathi, Z., Battey, J. and Jensen, R.: J Biol Chem 268, 20285-20290 (1993).
15. Birnbaumer, L., Ahramowitz, J. and Brown, A.: Biochim Biophys Acta 1031, 163-224 (1990).
16. Bluml, K., Mutschler, E. and Wess, J.: J Biol Chem 269, 18870-18876 (1994).
17. Boman, A. L. and Kahn, R. A.: Trends Biochem Sci 20, 147-150 (1995).
18. Bourne, H. R. and Nicoll, R.: Cell 72, 65-75 (1993).
19. Bouvier, M., Hausdorff, W., De, B.A., O'Dowd, B., Kobilka, B., Caron, M. and Lefkowitz, R.: Nature 333, 370-373 (1988).
20. Bouvier, M., Moffett, S., Loisel, T., Mouillac, B., Hebert, T. and Chidiac, P.: Biochem Soc Trans 23, 116-20 (1995).
21. Burstein, E., Spalding, T. and Brann, M.: J Biol Chem 271, 2882-2885 (1996).
22. Cali, J., Balcueva, E., Rybalkin, I. and Robishaw, J: J Biol Chem 267, 24023-24027 (1992).
23. Campbell, P., Hnatowich, M., O'Dowd, B., Caron, M., Lefkowitz, R. and Hausdorff, W: Mol Pharmacol 39, 192-198 (1991).
24. Cardinaud, B., Sugamori, K.S., Coudouel, S., Vincent, J.D., Niznik, H.B. and Vernier, P.: J Biol Chem 272, 2778-2787 (1997).
25. Carty, D., Padrell, E., Codina, J., Birnbaumer, L., Hildebrandt, J. and Iyengar, R: J Biol Chem 265, 6268-6273 (1990).
26. Cavalli, A., Fanelli, F., Taddei, C., DeBenedetti, P.G. and Cotecchia, S.:FEBS Lett 399, 9-13 (1996).
27. Cerione, R.A., Staniszewski, C., Benovic, J.L., Lefkowitz, R.J., Caron, M.G., Gierschik, P., Somers, R., Spiegel, A.M., Codina, J. and Birnbaumer, L.: J Biol Chem 260, 1493-1500 (1985).
28. Chabre, O., Conklin, B., Brandon, S., Bourne, H. and Limbird, L.: J Biol Chem 269, 5730-5734 (1994).
29. Chen, J., DeVivo, M., Dingus, J., Harry, A., Li, J., Sui, J., Carty, D., Blank, J., Exton, J., Stoffel, R. et al.: Science 268, 1166-1169 (1995).
30. Cheung, A., Huang, R., Graziano, M. and Strader, C: FEBS Lett 279, 277-280 (1991).
31. Chio, C.L., Lajiness, M.E. and Huff, R.M.: Mol Pharmacol 45, 51-60 (1994).
32. Chothia, C. and Finkelstein, A: Annu Rev Biochem 59, 1007-1039 (1990).
33. Chun, M., Lin, H., Henis, Y. and Lodish, H.: J Biol Chem 270, 10855-10860 (1995).
34. Clapham, D., Codina, J. and Birnbaumer, L.: Nature 379, 297-299 (1996).
35. Coleman, D., Berghuis, A., Lee, E., Linder, M., Gilman, A. and Sprang, S.: Science 265, 1405-1412 (1994).
36. Colombo, M.I., Inglese, J., D'Souza-Schorey, C., Beron, W. and Stahl, P. D.: J Biol Chem 270, 24564-24571 (1995).
37. Conklin, B., Chabre, O., Wong, Y., Federman, A. and Bourne, H.: J Biol Chem 267, 31-34 (1992).
38. Cotecchia, S., Exum, S., Caron, M. and Lefkowitz, R.: Proc Natl Acad Sci USA 87, 2896-2900 (1990).
39. Cotecchia, S., Ostrowski, J., Kjelsberg, M., Caron, M. and Lefkowitz, R.: J Biol Chem 267, 1633-1639 (1992).
40. Cox, B., Henningsen, R., Spanoyannis, A., Neve, R. and Neve, K.: J Neurochem 59, 627-635 (1992).
41. Dahl, S., Edvardsen, O. and Sylte, I.: Therapie 46, 453-459 (1991).
42. Dalman, H. and Neubig, R.: J Biol Chem 266, 11025-11029 (1991).
43. Degtyarev, M., Spiegel, A. and Jones, T: J Biol Chem 268, 23769-23772 (1993).
44. Demchyshyn, L.L., Sugamori, K.S., Lee, F.J., Hamadanizadeh, S.A. and Niznik, H.B.: J Biol Chem 270, 4005-4012 (1995).
45. Denker, B.M., Schmidt, C.J. and Neer, E.J.: J Biol Chem 267, 9998-10002 (1992).
46. Dixon, R., Sigal, I., Candelore, M., Register, R., Scattergood, W., Rands, E. and Strader, C.: EMBO J 6, 3269-3275 (1987).
47. Dixon, R., Sigal, I. and Strader, C: Cold Spring Harb Symp Quant Biol 53 Pt 1, 487-97 (1988).
48. Dohlman, H., Bouvier, M., Benovic, J., Caron, M. and Lefkowitz, R.: J Biol Chem 262, 14282-14288 (1987).
49. Dohlman, H., Caron, M., DeBlasi, A., Frielle, T. and Lefkowitz, R.: Biochemistry 29, 2335-2342 (1990).
50. Dohlman, H.,Thorner, J., Caron, M. and Lefkowitz, R: Annu Rev Biochem 60, 653-688 (1991).
51. Donnelly, D., Findlay, J. and Blundell, T.: Receptors Channels 2, 61-78 (1994).
52. Duboule, D., Boncinelli, E., DeRobertis, E., Featherstone, M., Lonai, P., Oliver, G. and Ruddle, F.H.: Genomics 7, 458-459 (1990).
53. Eason, M. and Liggett, S.: J Biol Chem 270, 24753-24760 (1995).
54. Eason, M. and Liggett, S.: J Biol Chem 271, 12826-12832 (1996).
55. Ehrlich, P., In: Readings in Pharmacology (1962), L. Schuster, ed. (Boston: Little Brown & Co), pp. 231-244.
56. Ehrlich, P: Lancet 2, 445-451 (1913).
57. Engelman, D., Steitz, T. and Goldman, A.: Annu Rev Biophys Biophys Chem 15, 321-353 (1986).
58. Felsenstein, J.: Annu Rev Genet 22, 521-565 (1988).
59. Ferguson, S., Downey, W.R., Colapietro, A., Barak, L., Menard, L. and Caron, M.: Science 277, 363-366 (1996).
60. Ferreira, P.A., Nakayama, T.A. and Travis, G.H.: Proc Natl Acad Sci USA 94, 1556-1561 (1997).
61. Fishburn, C.S., Elazar, Z. and Fuchs, S.: J Biol Chem 270, 29819-29824 (1995).
62. Fraser, C., Wang, C., Robinson, D., Gocayne, J. and Venter, J.: Mol Pharmacol 36, 840-847 (1989).
63. Galas, M.C., Helms, J.B., Vitale, N., Thierse, D., Aunis, D. and Bader, M.F.: J Biol Chem 272, 2788-2793 (1997).
64. Gantz, I., DelValle, J., Wang, L., Tashiro, T., Munzert, G., Guo, Y., Konda, Y. and Yamada, T.: J Biol Chem 267, 20840-20843 (1992).
65. Goldman, P., Schlador, M., Shapiro, R. and Nathanson, N: J Biol Chem 271, 4215-4222 (1996).
66. Green, S. and Liggett, S.: J Biol Chem 269, 26215-26219 (1994).
67. Groblewski, T., Maigret, B., Larguier, R., Lombard, C., Bonnafous, J.C. and Marie, J.: J Biol Chem 272, 1822-1826 (1997).
68. Gruenberg, J. and Clague, M.J.: Curr Opin Cell Biol 4, 593-599 (1992).
69. Gudermann, T., Kalkbrenner, F. and Schultz, G: Annu Rev Pharmacol Toxicol 36, 429-459 (1996).
70. Guiramand, J., Montmayeur, J., Ceraline, J., Bhatia, M. and Borrelli, E.: J Biol Chem 270, 7354-7358 (1995).
71. Hasegawa, H., Negishi, M. and Ichikawa, A.: J Biol Chem 271, 1857-1860 (1996).
72. Hausdorff, W., Bouvier, M., O'Dowd, B., Irons, G., Caron, M. and Lefkowitz, R.: J Biol Chem 264, 12657-12665 (1989).
73. Hausdorff, W., Hnatowich, M., O'Dowd, B., Caron, M. and Lefkowitz, R.: J Biol Chem 265, 1388-1393 (1990).
74. Hawes, B., Luttrell, L., Exum, S. and Lefkowitz, R.: J Biol Chem 269, 15776-15785.
75. Hebert, T., Moffett, S., Morello, J., Loisel, T., Bichet, D., Barret, C. and Bouvier, M.: J Biol Chem 271, 16384-16392 (1996).
76. Henderson, R., Baldwin, J., Ceska, T., Zemlin, F., Beckmann, E. and Downing, K.: J Mol Biol 213, 899-929 (1990).
77. Henderson, R. and Unwin, P.: Nature 257, 28-32 (1975).
78. Hermans, E., Octave, J. and Maloteaux, J: Mol Pharmacol 49, 365-372 (1996).
79. Hibert, M., Trumpp-Kallmeyer, S., Bruinvels, A. and Hoflack, J.: Mol Pharmacol 40, 8-15 (1991).
80. Hibert, M., Trumpp-Kallmeyer, S., Hoflack, J. and Bruinvels, A.: Trends Pharmacol Sci 14, 7-12 (1993).
81. Higashijima, T., Uzu, S., Nakajima, T. and Ross, E.: J Biol Chem 263, 6491-6494 (1988).
82. High, S. and Dobberstein, B.: Curr Opin Cell Biol 4, 581-586 (1992).
83. Hill-Eubanks, D., Burstein, E., Spalding, T., Brauner-Osborne, H. and Brann, M.: J Biol Chem 271, 3058-65 (1996).
84. Ho, B.Y., Karschin, A., Branchek, T., Davidson, N. and Lester, H.A.: FEBS Lett 312, 259-262 (1992).
85. Hogger, P., Shockley, M., Lameh, J. and Sadee, W.: J Biol Chem 270, 7405-7410 (1995).
86. Hsu, W., Rudolph, U., Sanford, J., Bertrand, P., Olate, J., Nelson, C., Moss, L., Boyd, A., Codina, J. and Birnbaumer, L: J Biol Chem 265, 11220-11226 (1990).
87. Humphrey, P. P., Hartig, P. and Hoyer, D.: Trends Pharmacol Sci 14, 233-236 (1993).
88. Hwa, J., Graham, R. and Perez, D.: J Biol Chem 270, 23189-23195 (1995).
89. Hwa, J., Graham, R. and Perez. D.: J Biol Chem 277, 7956-7964 (1996a).
90. Hwa,J. and Ferez, D.: J Biol Chem 277, 6322-6327 (1996b).
91. Inglese, J., Freedman, N., Koch, W. and Lefkowitz, R.: J Biol Chem 268, 23735-23738 (1993).
92. Javitch, J., Fu, D. and Chen, J.: Biochemistry 34, 16433-16439 (1995a).
93. Javitch, J., Fu, D., Chen, J. and Karlin, A.: Neuron 14, 825-831 (1995b).
94. Jensen, A.A., Pedersen, U.B., Kiemer, A., Din, N. and Andersen, P.H.: J Neurochem 65, 1325-1331 (1995).
95. Johannes, F., Prestle, J., Dieterich, S., Oberhagemann, P., Link, G. and Pfizenmaier, K.: Eur J Biochem 227, 303-307 (1995).
96. Kahlert, M., Konig, B. and Hofmann, K.: J Biol Chem 265, 18928-18932 (1990).
97. Kawate, N. and Menon, K.: J Biol Chem 269, 30651-30658 (1994).
98. Kenakin, T.R: Trends Pharmacol Sci 4, 291-295 (1983).
99. Kjelsberg, M., Cotecchia, S., Ostrowski, J., Caron, M. and Lefkowitz, R.: J Biol Chem 267, 1430-1433 (1992).
100. Kleuss, C., Hescheler, J., Ewel, C., Rosenthal, W., Schultz, G. and Wittig, B.: Nature 353, 43-48 (1991).
101. Kleuss, C., Scherubl, H., Hescheler, J., Schultz, G. and Wittig, B.: Nature 558, 424-426 (1992).
102. Kleuss, C., Scherubl, H., Hescheler, J., Schultz, G. and Wittig, B.: Science 259, 832-834 (1993).
103. Kobilka, B., Kobilka, T., Daniel, K., Regan, J., Caron, M. and Lefkowitz, R.: Science 240, 1310-1316 (1988).
104. Koenig, J. and Edwardson, J.: Mol Pharmacol 49, 351-359 (1996).
105. Kubo, T., Bujo, H., Akiba, I., Nakai, J., Mishina, M. and Numa, S.: FEBS Lett 241, 119-125 (1988).
106. Kuipers, W., Van, W.I. and Ijzerman, A.: Drug Res Discov 11, 231-249 (1994).
107. Lambright, D., Noel, J., Hamm, H. and Sigler, P.: Nature 569, 621-628 (1994).
108. Lambright, D., Sondek, J., Bohm, A., Skiba, N., Hamm, H. and Sigler, P.: Nature 379, 311-319 (1996).
109. Lameh, J., Philip, M., Sharma, Y., Moro, O., Ramachandran, J. and Sadee,W.: J Biol Chem 207, 13406-13412 (1992).
110. Langley, IN.: J Physiol (London) 55, 374-413 (1905).
111. Lattion, A., Diviani, D. and Cotecchia, S.: J Biol Chem 269, 22887-22893 (1994).
112. Laugwitz, K.L., Allgeier, A., Offermanns, S., Spicher, K., Van Sande, J., Dumont, J.E. and Schultz, G: Proc Natl Acad Sci USA 95, 116-120 (1996).
113. Lechleiter, J., Hellmiss, R., Duerson, K., Ennulat, D., David, N., Clapham, D. and Peralta, E.: EMBO J 9, 4381-4390 (1990).
114. Lee, C.,Katz,A. and Simon, M.: Mol Pharmacol 47, 218-223 (1995).
115. Leyte, A., Barr, F.A., Kehlenbach, R.H. and Huttner, W.B.: EMBO J 11, 4795-4804 (1992).
116. Liggett, S., Ostrowski, J., Chesnut, L., Kurose, H., Raymond, J., Caron, M. and Lefkowitz, R.: J Biol Chem 267, 4740-4746 (1992).
117. Linder, M., Ewald, D., Miller, R. and Oilman, A.: J Biol Chem 265, 8243-8251 (1990).
118. Lisanti, M., Scherer, P.E., Tang, Z.L. and Sargiacomo, M.: Trends Cell Sci 4, 231-235 (1994).
119. Liu, X., Davis, D. and Segaloff, D. L.: J Biol Chem 268, 1513-1516 (1993).
120. Liu, J., Powell, K., Sudhof, T. and Robinson, P.: J Biol Chem 269, 21043-21050 (1994).
121. Liu, J., Blin, N., Conklin, B. and Wess, J: J Biol Chem 277, 6172-6178 (1996).
122. Lledo, P.M., Homburger, V., Bockaert, J., Vincent, J.D., Lledo, P.M., Homburger, V., Bockaert, J. and Vincent, J.D.: Neuron 8, 455-463 (1992).
123. Lledo, P.-M., Vernier, P., Kukstas, L. A., Vincent, J.-D., Homburger, V. and Bockaert, J., In: Dopamine receptors and transporters, H.B. Niznik, ed. (New York: Marcel Dekker Inc.), pp. 59-88 (1994).
124. Logothetis, D., Kurachi, Y., Galper, J., Neer, E. and Clapham, D.: Nature 325, 321-326 (1987).
125. Lohse, M. Andexinger, S., Pitcher, J., Trukawinski, S., Codina, J., Faure, J., Caron, M. and Lefkowitz, R.: J Biol Chem 267, 8558-8564 (1992).
126. Lohse, M., Benovic, J., Caron, M. and Lefkowitz, R.: J Biol Chem 265, 3202-3211 (1990a).
127. Lohse, M., Benovic, J., Codina, J., Caron, M. and Lefkowitz, R.: Science 248, 1547-1550 (1990b).
128. Luttrell, L., Ostrowski, J., Cotecchia, S., Kendall, H. and Lefkowitz, R.: Science 259, 1453-1457 (1993).
129. Luttrell, L.M., Hawes, B.E., van Biesen, T., Luttrell, D.K., Lansing, T.J. and Lefkowitz, R.J.: J Biol Chem 271, 19443-19450 (1996).
130. Maggio, R., Vogel, Z. and Wess, J.: FEBS Lett 319, 195-200 (1993a).
131. Maggio, R., Vogel, Z. and Wess, J.: Proc Natl Acad Sci USA 90, 3103-3107 (1993b).
132. Mansour, A., Meng, F., Meador-Woodruff, J., Taylor, L., Civelli, O. and Akil, H.: Eur J Pharmacol 227, 205-214 (1992).
133. Moffett, S., Mouillac, B., Bonin, H. and Bouvier, M.: EMBO J 12, 349-356 (1993).
134. Montmayeur, J., Guiramand, J. and Borrelli, E.: Mol Endocrinol 7, 161-170 (1993).
135. Moro, O., Lameh, J., Hogger, P. and Sadee, W.: J Biol Chem 268, 22273-22276 (1993a).
136. Moro, O., Lameh, J. and Sadee, W: J Biol Chem 268, 6862-6865 (1993b).
137. Moro, O., Shockley, M., Lameh, J. and Sadee, W.: J Biol Chem 269, 6651-6655 (1994).
138. Munro, S.: EMBO J 10, 3577-3588 (1991).
139. Namba, T., Sugimoto, Y., Negishi, M., Irie, A., Ushikubi, F., Kakizuka, A., Ito, S., Ichikawa, A. and Narumiya, S.: Nature 365, 166-170 (1993).
140. Neer, E.J.: Cell 80, 249-257 (1995).
141. Nicholas, A.P., Hokfelt, T. and Pieribone, V.A.: Trends Pharmacol Sci 17, 245-255 (1996).
142. Nicholas, A.P., Pieribone, V.A. and Hokfelt, T.: Neuroscience 56, 1023-1039 (1993).
143. Noel, J., Hamm, H. and Sigler, P.: Nature 366, 654-663 (1993).
144. O'Dowd, B., Hnatowich, M., Caron, M., Lefkowitz, R. and Bouvier, M.: J Biol Chem 264, 7564-7569 (1989).
145. O'Dowd, B.F., Hnatowich, M., Regan, J.W., Leader, W.M., Caron, M.G. and Lefkowitz, R.J.: J Biol Chem 263, 15985-15992 (1988).
146. Ohta, K., Hayashi, H., Mizuguchi, H., Kagamiyama, H., Fujimoto, K. and Fukui, H.: Biochem Biophys Res Commun 203, 1096-1101 (1994).
147. Okamoto, T., Murayama, Y., Hayashi, Y., Inagaki, M., Ogata, E. and Nishimoto, I.: Cell 67, 723-730 (1991).
148. Parent, J., Le Grouill, C., de Brum-Fernandes, A., Rola-Pleszczynski, M. and Stankova, J.: J Biol Chem 271, 7949-7955 (1996).
149. Parma, J., Duprez, L., Van, S.J., Cochaux, P., Gervy, C., Mockel, J., Dumont, J. and Vassart, G.: Nature 365, 649-651 (1993).
150. Pelham, H.R. and Munro, S.: Cell 75, 603-605 (1993).
151. Perez, D., Hwa, J., Gaivin, R., Mathur, M., Brown, F. and Graham, R.: Mol Pharmacol 49, 112-122 (1996).
152. Perez, D.M., Hwa, J., Gaivin, R., Mathur, M., Brown, F. and Graham, R.M.: Mol Pharmacol 49, 112-122 (1997).
153. Pimplikar, S.W. and Simons, K.: J Cell Sci Suppl 17, 27-32 (1993).
154. Piomelli, D., Pilon, C., Giros, B., Sokoloff, P., Martres, M.P. and Schwartz, J.C.: Nature 353, 164-167 (1991).
155. Pitcher, J.A., Inglese, J., Higgins, J. B., Arriza, J.L., Casey, P. J., Kim, C., Benovic, J.L., Kwatra, M.M., Caron, M.G. and Lefkowitz, R.J.: Science 257, 1264-1267 (1992).
156. Pollock, N., Manelli, A., Hutchins, C., Steffey, M., MacKenzie, R. and Frail, D.: J Biol Chem 267, 17780-17786 (1992).
157. Popot, J. and Engelman, D.: Biochemistry 29, 4031-4037 (1990).
158. Premont, R., Koch, W., Inglese, J. and Lefkowitz, R.: J Biol Chem 269, 6832-6841 (1994).
159. Premont, R., Inglese, J. and Lefkowitz, R.: FASEB J 9, 175-182 (1995).
160. Premont, R., Macrae, A., Stoffel, R., Chung, N., Pitcher, J., Ambrose, C., Inglese, J., MacDonad, M. and Lefkowitz, R: J Biol Chem 277, 6403-6410 (1996).
161. Prezeau, L., Gomeza, J., Ahern, S., Mary, S., Galvez, T., Bockaert, J. and Pin, J.: Mol Pharmacol 49, 422-429 (1996).
162. Pronin, A. and Gautam, K: Proc Natl Acad Sci USA 89, 6220-6224 (1992).
163. Rands, E., Candelore, M.R., Cheung, A.H., Hill, W.S., Strader, C.D. and Dixon, R. A.: J Biol Chem 265,10759-10764 (1990).
164. Raposo, G., Dunia, I., Delavier-Klutchko, C., Kaveri, S., Strosberg, A. and Benedetti, E.: Eur J Cell Biol 50, 340-52 (1989).
165. Ren, Q., Kurose, H., Lefkowitz, R. and Cotecchia, S.: J Biol Chem 265, 16483-16487 (1993).
166. Roth, N., Campbell, P., Caron, M., Lefkowitz, R. and Lohse, M.: Proc Natl Acad Sci USA 55, 6201-6204 (1991).
167. Saitou, N. and Nei, M.: Mol Biol Evol 4, 406-425 (1987).
168. Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K. and Masaki, T.: Nature 348, 732-735 (1990).
169. Samama, P., Cotecchia, S., Costa, T. and Lefkowitz, R.: J Biol Chem 268, 4625-4636 (1993).
170. Schatz, G. and Dobberstein, B.: Science 271, 1519-1526 (1996).
171. Scheer, A., Fanelli, F., Costa, T., De, B.P. and Cotecchia, S.: EMBO J 15, 3566-3578 (1996).
172. Scheer, A., Fanelli, F., Costa, T., DeBenedetti, P.O. and Cotecchia, S.: Proc Natl Acad Sci USA 94, 808-813 (1997).
173. Schertler, G., Villa, C. and Henderson, R.: Nature 362, 770-772 (1993).
174. Schwartz, T.W., Gether, U., Schambye, H.T. and Hjorth, S.A.: Current Pharmaceutical Design 1, 355-372 (1995).
175. Senogles, S.: J Biol Chem 269, 23120-23127 (1994).
176. Senogles, S.E., Spiegel, A.M., Padrell, E., Iyengar, R. and Caron, M.G.: J Biol Chem 265, 4507-4514 (1990).
177. Shapiro, R., Palmer, D. and Cislo, T.: J Biol Chem 268, 21734-21738 (1993).
178. Shaw, G.: Bioessays 18, 35-46 (1996).
179. Shenker, A., Laue, L., Kosugi, S., Merendino, J.J., Minegishi, T. and Cutler, G.J.: Nature 365, 652-654 (1993).
180. Sibley, D., Strasser, R., Benovic, J., Daniel, K. and Lefkowitz, R: Proc Natl Acad Sci USA 83, 9408-9412 (1986).
181. Siderovski, D. P., Hessel, A., Chung, S., Mak, T.W. and Tyers, M.: Curr Biol 6, 211-212 (1996).
182. Simon, M., Strathmann, M. and Gautam, K: Science 252, 802-808 (1991).
183. Smrcka, A.V. and Sternweis, P.C.: J Biol Chem 268, 9667-9674 (1993).
184. Sokoloff,P. and Schwartz, J.C.:Trends Pharmacol Sci 16, 270-275 (1995).
185. Sondek, J., Bohm, A., Lambright, D., Hamm, H. and Sigler, P.: Nature 379, 369-374 (1996).
186. Spalding, T., Burstein, E., Brauner-Osborne, H., Hill-Eubanks, D. and Brann, M.: J Pharmacol Exp Ther 275, 1274-1279 (1995).
187. Spengler, D., Waeber, C., Pantaloni, C., Holsboer, F., Bockaert, J., Seeburg, P. and Journot, L.: Nature 365, 170-175 (1993).
188. Stoffel, R., Randall, R., Premont, R., Lefkowitz, R. and Inglese, J.: J Biol Chem 269, 27791-27794 (1994).
189. Strader, C., Candelore, M., Hill, W., Sigal, I. and Dixon, R.: J Biol Chem 264, 13572-13578 (1989).
190. Strader, C., Dixon, R., Cheung, A., Candelore, M., Blake, A. and Sigal, I.: J Biol Chem 262, 16439-16443 (1987b).
191. Strader, C., Gaffney, T., Sugg, E., Candelore, M., Keys, R., Patchett, A. and Dixon, R.: J Biol Chem 266, 5-8 (1991).
192. Strader, C., Sigal, I., Blake, A., Cheung, A., Register, R., Rands, E., Zemcik, B., Candelore, M. and Dixon, R.: Cell 49, 855-863 (1987a).
193. Strader, C., Sigal, I., Candelore, M., Rands, E., Hill, W. and Dixon, R.: J Biol Chem 263, 10267-10271.
194. Strange, P.G., In: Advances in Drug Research, Vol. 28, B. Testa and U. A. Meyer, eds. (24-28 Oval Road, London, England NW1 7DX: Academic Press Ltd), pp. 313-351 (1996).
195. Sullivan, K.A., Miller, R.T., Masters, S.B., Beiderman, B., Heideman, W. and Bourne, H. R.: Nature 330, 758-760 (1987).
196. Sunahara, R.K., Dessauer, C.W. and Gilman, A.G.: Annu Rev Pharmacol Toxicol 36, 461-480 (1996).
197. Thomas, W., Thekkumkara, T., Motel, T. and Baker, K.: J Biol Chem 270, 207-213 (1995).
198. Tiberi, M. and Caron, M.: J Biol Chem 269, 27925-27931 (1994).
199. Tomic, M., Seeman, P., George, S. and O'Dowd, B.: Biochem Biophys Res Commun 191, 1020-1027 (1993).
200. Touhara, K., Inglese, J., Pitcher, J., Shaw, G. and Lefkowitz, R.: J Biol Chem 269, 10217-10220 (1994).
201. Tsuga, H., Kameyama, K., Haga, T., Kurose, H. and Nagao, T.: J Biol Chem 269, 32522-32527 (1994).
202. Tsukamoto, T., Toyama, R., Itoh, H., Kozasa, T., Matsuoka, M. and Kaziro, Y.: Proc Natl Acad Sci USA 88, 2974-2978 (1991).
203. Vallar, L., Muca, C., Civelli, O. and Meldolesi, J.: Neurochem Int 20, 197S-200S (1992).
204. van Biesen, T., Hawes, B.E., Luttrell, D.K., Krueger, K.M.,Touhara, K.,Porfiri, E., Sakaue, M., Luttrell, L.M. and Lefkowitz, R.J.: Nature 376, 781-784 (1995).
205. Vanhoutte, P.M., Humphrey, P.P. and Spedding, M.: Pharmacol Rev 48, 1-2 (1996).
206. Vernier, P., Cardinaud, B., Valdenaire, O., Philippe, H. and Vincent, ID.: Trends Pharmacol Sci 16, 375-381 (1995).
207. von Heijne, G. and Gavel, Y.: Eur J Biochem 174, 671-678 (1988).
208. von Heijne, G. and Manoil, C.: Protein Eng 4, 109-112 (1990).
209. von Zastrow, M. and Kobilka, B.: J Biol Chem 267, 3530-3538 (1992).
210. Vuong, T. and Chabre, M.: Nature 346, 71-74 (1990).
211. Wall, M., Coleman, D., Lee, E., Iniguez-Lluhi, J., Posner, B., Oilman, A. and Sprang, S.: Cell 83, 1047-1058 (1995).
212. Wang, C, Buck, M. and Fraser, C.: Mol Pharmacol 40, 168-179 (1991).
213. Wang, C., Gallaher, T. and Shih, J: Mol Pharmacol 43, 931-940 (1993).
214. Wang, H., Lipfert, L., Malbon, C. and Bahouth, S.: J Biol Chem 264, 14424-14431 (1989).
215. Watson, A., Katz, A. and Simon, M.: J Biol Chem 269, 22150-22156 (1994).
216. Wess, J., Bonner,T., Dorje, F. and Brann, M.: Mol Pharmacol 38, 517-523 (1990).
217. Wess, J., Gdula, D. and Brann, M.: EMBO J 10, 3729-3734 (1991).
218. Wess, J., Maggio, R., Palmer, J. and Vogel, Z.: J Biol Chem 267, 19313-19319 (1992).
219. Whitehead, I., Kirk, H., Tognon, C., Trigo-Gonzalez, G. and Kay, R.: J Biol Chem 270, 18388-18395 (1995).
220. Wong, S., Parker, E. and Ross, E.: J Biol Chem 265, 6219-6224 (1990).
221. Woodward, R., Coley, C., Daniell, S., Naylor, L. and Strange, P.: J Neurochem 66, 394-402 (1996).
222. Yoon, H., Hajduk, P., Petros, A., Olejniczak, E., Meadows, R. and Fesik, S.: Nature 369, 672-675 (1994).
223. Yu, S., Lefkowitz, R. and Hausdorff, W.: J Biol Chem 268, 337-341 (1993).
224. Zhang, J., Ferguson, S., Barak, L., Menard, L. and Caron, M.: J Biol Chem 271, 18302-18305 (1996).
225. Zuckerkandl, E.: J Mol Evol 39, 661-678 (1994).