-
1
-
-
0028350882
-
De la membrane au noyau, un couplage direct entre les récepteurs de cytokines et la machinerie transcriptionnelle
-
Kahn A. De la membrane au noyau, un couplage direct entre les récepteurs de cytokines et la machinerie transcriptionnelle. Med Sci 1994; 10: 202-5.
-
(1994)
Med Sci
, vol.10
, pp. 202-205
-
-
Kahn, A.1
-
3
-
-
0030272581
-
Roles of the JAK-STAT system in signal transduction via cytokine receptors
-
Watanabe S, Arai KI. Roles of the JAK-STAT system in signal transduction via cytokine receptors. Curr Opin Genet Dev 1996; 6: 587-96.
-
(1996)
Curr Opin Genet Dev
, vol.6
, pp. 587-596
-
-
Watanabe, S.1
Arai, K.I.2
-
4
-
-
0030156250
-
Intracellular signalling: Putting JAKs on the kinase MAP
-
Winston LA, Hunter T. Intracellular signalling: putting JAKs on the kinase MAP. Curr Biol 1996; 6: 668-71.
-
(1996)
Curr Biol
, vol.6
, pp. 668-671
-
-
Winston, L.A.1
Hunter, T.2
-
5
-
-
0030765924
-
Jaks, Stats, cytokine signal transduction and immunoregulation: Are we there yet?
-
O'Shea JJ. Jaks, Stats, cytokine signal transduction and immunoregulation: are we there yet? Immunity 1997; 7: 1-11.
-
(1997)
Immunity
, vol.7
, pp. 1-11
-
-
O'Shea, J.J.1
-
6
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell J Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-21.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.1
Kerr, I.M.2
Stark, G.R.3
-
7
-
-
0028922433
-
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6
-
Guschin D, Rogers N, Briscoe J, Witthuhn B, Watling D, Horn F, Pellegrini S, Yasukawa K, Heinrich P, Stark GR, Ihle JN. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. EMBO J 1995; 14: 1421-9.
-
(1995)
EMBO J
, vol.14
, pp. 1421-1429
-
-
Guschin, D.1
Rogers, N.2
Briscoe, J.3
Witthuhn, B.4
Watling, D.5
Horn, F.6
Pellegrini, S.7
Yasukawa, K.8
Heinrich, P.9
Stark, G.R.10
Ihle, J.N.11
-
8
-
-
0029917296
-
Participation of JAK and STAT proteins in growth hormone-induced signaling
-
Han Y, Leaman DW, Watling D, Rogers NC, Groner B, Kerr IM, Wood WI, Stark GR. Participation of JAK and STAT proteins in growth hormone-induced signaling. J Biol Chem 1996; 271: 5947-52.
-
(1996)
J Biol Chem
, vol.271
, pp. 5947-5952
-
-
Han, Y.1
Leaman, D.W.2
Watling, D.3
Rogers, N.C.4
Groner, B.5
Kerr, I.M.6
Wood, W.I.7
Stark, G.R.8
-
9
-
-
0029656001
-
Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor
-
Leaman DW, Pisharody S, Flickinger TW, Commane MA, Schlessinger J, Kerr IM, Levy DE, Stark GR. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Mol Cell Biol 1996; 16: 369-75.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 369-375
-
-
Leaman, D.W.1
Pisharody, S.2
Flickinger, T.W.3
Commane, M.A.4
Schlessinger, J.5
Kerr, I.M.6
Levy, D.E.7
Stark, G.R.8
-
10
-
-
0029966664
-
Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins
-
Vignais ML, Sadowski HB, Watling D, Rogers NC, Gilman MZ. Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 1996; 16: 1759-69.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1759-1769
-
-
Vignais, M.L.1
Sadowski, H.B.2
Watling, D.3
Rogers, N.C.4
Gilman, M.Z.5
-
11
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z, Zhong Z, Darnell JE Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995; 82: 241-50.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
12
-
-
0029936611
-
Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway
-
Beadling C, Ng J, Babbage JW, Cantrell DA. Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway. EMBO J 1996; 15: 1902-13.
-
(1996)
EMBO J
, vol.15
, pp. 1902-1913
-
-
Beadling, C.1
Ng, J.2
Babbage, J.W.3
Cantrell, D.A.4
-
13
-
-
0029887373
-
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp 130
-
Gerhartz C, Heesel B, Sasse I, Hemmann U, Landgraf C, Schneider-Mergener J, Horn F, Heinrich PC, Graeve L. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp 130. J Biol Chem 1996; 271: 12991-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 12991-12998
-
-
Gerhartz, C.1
Heesel, B.2
Sasse, I.3
Hemmann, U.4
Landgraf, C.5
Schneider-Mergener, J.6
Horn, F.7
Heinrich, P.C.8
Graeve, L.9
-
14
-
-
0029903770
-
DNA binding of in vivo activated Stat1α, STAT1β and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
-
Vinkemeier U, Cohen SL, Moarefi I, Chait BT, Kuriyan J, Darnell JE Jr. DNA binding of in vivo activated Stat1α, STAT1β and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J 1996; 15: 5616-26.
-
(1996)
EMBO J
, vol.15
, pp. 5616-5626
-
-
Vinkemeier, U.1
Cohen, S.L.2
Moarefi, I.3
Chait, B.T.4
Kuriyan, J.5
Darnell Jr., J.E.6
-
15
-
-
0029851231
-
Functional interactions between Stat5 and the glucocorticoid receptor
-
Stöcklin E, Wissler M, Gouilleux F, Groner B. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 1996; 383: 726-8.
-
(1996)
Nature
, vol.383
, pp. 726-728
-
-
Stöcklin, E.1
Wissler, M.2
Gouilleux, F.3
Groner, B.4
-
16
-
-
0029767462
-
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α
-
Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α. Nature 1996; 383: 344-7.
-
(1996)
Nature
, vol.383
, pp. 344-347
-
-
Bhattacharya, S.1
Eckner, R.2
Grossman, S.3
Oldread, E.4
Arany, Z.5
D'Andrea, A.6
Livingston, D.M.7
-
17
-
-
0029811474
-
Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells
-
Tagaya Y, Burton JD, Miyamoto Y, Waldmann TA. Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells. EMBO J 1996; 15: 4928-39.
-
(1996)
EMBO J
, vol.15
, pp. 4928-4939
-
-
Tagaya, Y.1
Burton, J.D.2
Miyamoto, Y.3
Waldmann, T.A.4
-
18
-
-
0030024563
-
Targeted disruption of the mouse Statl gene results in compromised innate immunity to viral disease
-
Durbin JE, Hackenmiller R, Simon MC, Levy DE. Targeted disruption of the mouse Statl gene results in compromised innate immunity to viral disease. Cell 1996; 84: 443-50.
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
19
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz MA, White JM, Sheehan KCF, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Campbell D, Carver-Moore K, Dubois RN, Clark R, Aguet M, Schreiber RD. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996; 84: 431-42.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.F.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
Carver-Moore, K.11
Dubois, R.N.12
Clark, R.13
Aguet, M.14
Schreiber, R.D.15
-
20
-
-
0029975904
-
STAT3 activation is a critical step in gp130-medialed terminal differentiation and growth arrest of a myeloid cell line
-
Minami M, Inoue M, Wei S, Takeda K, Matsumoto M, Kishimoto T, Akira S. STAT3 activation is a critical step in gp130-medialed terminal differentiation and growth arrest of a myeloid cell line. Proc Natl Acad Sci USA 1996; 93: 3963-6.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3963-3966
-
-
Minami, M.1
Inoue, M.2
Wei, S.3
Takeda, K.4
Matsumoto, M.5
Kishimoto, T.6
Akira, S.7
-
21
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996; 382: 174-7.
-
(1996)
Nature
, vol.382
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
22
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder WE, van Deursen J, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DAA, Doherty PC, Grosveld G, Ihle JN. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996; 382: 171-4.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
Van Deursen, J.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.A.8
Doherty, P.C.9
Grosveld, G.10
Ihle, J.N.11
-
23
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
-
Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 1996; 4: 313-9.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
24
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DAA, Doherty PC, Grosveld G, Paul WE, Ihle JN. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996; 380: 630-3.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
-
25
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda K, Tanaka T, Shi W, Matsumoto M, Minami M, Kashiwamura SI, Nakanishi K, Yoshida N, Kishimoto T, Akira S. Essential role of Stat6 in IL-4 signalling. Nature 1996; 380: 627-30.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.I.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
26
-
-
0028956353
-
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
-
Klingmüller U, Lorentz U, Cantley LC, Neel BG, Lodish HF. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995; 80: 729-38.
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmüller, U.1
Lorentz, U.2
Cantley, L.C.3
Neel, B.G.4
Lodish, H.F.5
-
27
-
-
0000413462
-
Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway
-
Kim TK, Maniatis T. Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science 1996; 273: 1717-9.
-
(1996)
Science
, vol.273
, pp. 1717-1719
-
-
Kim, T.K.1
Maniatis, T.2
-
28
-
-
0029164841
-
Mutation of Jak-3 gene in patients with autosomal severe combined deficiency (SCID)
-
Macchi M, Villa A, Giliani S, Sacco MG, Frattini A, Porta F, Ugazio AG, Johnston JA, Candotti F, O'Shea JJ, Vezzoni P, Notarangelo LD. Mutation of Jak-3 gene in patients with autosomal severe combined deficiency (SCID). Nature 1995; 377: 65-8.
-
(1995)
Nature
, vol.377
, pp. 65-68
-
-
Macchi, M.1
Villa, A.2
Giliani, S.3
Sacco, M.G.4
Frattini, A.5
Porta, F.6
Ugazio, A.G.7
Johnston, J.A.8
Candotti, F.9
O'Shea, J.J.10
Vezzoni, P.11
Notarangelo, L.D.12
-
29
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russel SM, Tayebi N, Nakajima H, Riedy MC, Roberts JL, Javad Aman M, Migone TS, Noguchi M, Markert ML, Buckley RH, O'Shea JJ, Leonard WJ. Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science 1995; 270: 797-800.
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russel, S.M.1
Tayebi, N.2
Nakajima, H.3
Riedy, M.C.4
Roberts, J.L.5
Javad Aman, M.6
Migone, T.S.7
Noguchi, M.8
Markert, M.L.9
Buckley, R.H.10
O'Shea, J.J.11
Leonard, W.J.12
-
30
-
-
0029005549
-
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-1
-
Migone TS, J-X L, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard WJ. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-1. Science 1995; 269: 79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.S.1
J-X, L.2
Cereseto, A.3
Mulloy, J.C.4
O'Shea, J.J.5
Franchini, G.6
Leonard, W.J.7
-
31
-
-
0029791664
-
Unique signal transduction of Eyk: Constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase
-
Zong C, Yan R, August A, Darnell JE Jr. Unique signal transduction of Eyk: constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase. EMBO J 1996; 15: 4515-25.
-
(1996)
EMBO J
, vol.15
, pp. 4515-4525
-
-
Zong, C.1
Yan, R.2
August, A.3
Darnell Jr., J.E.4
-
32
-
-
0028968949
-
Tyrosine kinase inhibition: An approach to drug development
-
Levitzki A, Gazit A. Tyrosine kinase inhibition: an approach to drug development. Science 1995; 267: 1782-8.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
|