Cell cycle: Will the real Cdk-activating kinase please stand up

Current Biology

Volumn 7, Issue 1, 1997, Pages

  Draetta, Giulio F ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031026679     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00020-0     Document Type: Review

References (24)

1. De Bondt HL, Rosenblatt J, Jancarik J, Jones HD, Morgan DO, Kim SH : Crystal structure of human cdk2: implications for the regulation of cyclin-dependent kinases by phosphorylation and cyclin binding. Nature 1993, 363:595-602.
2. Jeffrey PD, Russo AA, Polyak K, Gibbs E, Hurwitz J, Massague J, Pavletich NP: Mechanism of CDK activation revealed by the structure of a cyclin A-CDK2 complex. Nature 1995, 376313-320.
3. Draetta G F: Cdc2 activation: the interplay of cyclin binding and Thr161 phosphorylation. Trends Cell Biol 1993, 3:287-289.
4. Morgan M: Principles of cdk regulation. Nature 1995, 374:131-134.
5. +, a cell cycle control gene of the fission yeast Schizosaccharomyces pombe. Mol Cell Biol 1986, 6:3523-3530.
6. Ducommun B, Brambilla P, Felix M-A, Franza BRJ, Karsenti E, Draetta G: Cdc2 phosphorylation is required for its interaction with cyclin. EMBO J 1991, 11:3311-3319.
7. cdc2 activity: identification of Th161 as an essential in vivo phosphorylation site. New Biol 1992, 4:323-329.
8. cdc2 activation: identification of an activating kinase. Mol Biol Cell 1992, 3:13-27.
9. Fesquet D, Labbe JC, Derancourt J, Capony JP, Galas S, Girard F, Lorca T, Shuttleworth J, Doree M, Cavadore JC: The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of threonine 161 and its homologs. EMBO J 1993, 12:3111-3121.
10. cdk2-activating kinase. EMBO J 1993, 12:3123-3132.
11. cdc2 activating kinase contains a protein related to MO15. EMBO J 1993, 12:3133-3142.
12. Fisher RP, Morgan DO: A novel cyclin associates with MO15/ CDK7 to form the CDK-activating kinase. Cell 1994, 78:713-724.
13. Makela TP, Tassan J, Nigg EA, Frutiger S, Hughes GJ, Weinberg RA: A cyclin associated with the CDK-activating kinase M015. Nature 1994, 371:254-257.
14. Devault A, Martinez AM, Fesquet D, Labbe JC, Morin N, Tassan JP, Nigg EA , Cavadore JC, Doree M: MAT1 ('menage a trois'), a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. EMBO J 1995, 14:5027-5036.
15. Fisher RP, Jin P, Chamberlin HM, Morgan DO: Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. Cell 1995, 83:47-57.
16. Bartkova J, Zemanova M, Bartek J: Expression of CDK7/ CAK in normal and tumor cells of diverse histogenesis, cell-cycle position and differentiation. Int J Cancer 1996, 66:732-737.
17. Seroz T, Hwang JR, Moncollin V, Egly JM: TFIIH: a link between transcription, DNA repair and cell cycle regulation. Curr Opin Genet Dev 1995, 5:217-221.
18. Buck V, Russell P, Millar JB: Identification of a cdk-activating kinase in fission yeast. EMBO J 1995, 14:6173-6183.
19. Damagnez V, Makela TP, Cottarel G: Schizosaccharomyces pombe Mop1-Mcs2 is related to mammalian CAK. EMBO J 1995, 14:6164-72.
20. Molz L, Beach D: Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. EMBO J 1993, 12:1723-32.
21. Molz L, Booher R, Young P, Beach D: Cdc2 and the regulation of mitosis: six interacting mcs genes. Genetics 1989, 122:773-782.
22. Espinoza FE, Farrell A, Erdjument-Bromage H, Tempts P, Morgan DO: A cyclin-dependent kinase-activating kinase in budding yeast unrelated to vertebrate CAK. Science 1996, 273:1714-1716.
23. Kadis P, Sutton A, Solomon MJ:. The Cdk-activating kinase (CAK) from budding yeast. Cell 1996, 86:553-564.
24. Thuret JY, Valay JG, Faye G, Mann C: Civ1 (CAK in vivo), a novel Cdk-activating kinase. Cell 1996, 86:565-576.