Contribution of cohort studies in understanding HIV pathogenesis: Introduction of the GRIV cohort and preliminary results

Biomedicine and Pharmacotherapy

Volumn 50, Issue 10, 1996, Pages 480-487

  Hendel, H ^a   Cho, Y Y ^a   Gauthier, N ^b   Rappaport, J ^c   Schachter F ^b   Zagury, J F ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b Ctr d'Etud du Polymorphisme Humain 27 Rue Juliette Dodu 75010   (France)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; DISEASE COURSE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

EID: 0030467289     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(97)89278-5     Document Type: Article

References (72)

1. 1 Pantaleo G, Menzo S, Vaccarezza M et al. Studies in subjects with long-term non progressive human immunodeficiency virus infection. N Engl J Med 1995;332:209-16
2. 2 Haynes BF, Pantaleo G, Fauci AS. Toward an understanding of the correlates of protective immunity to HIV infection. Science 1996;271:324-8
3. 3 Cao Y, Qin L, Zhang L, Safrit J, Ho DD. Virologic and immunologic characterisation of long-term survivors of human immunodeficiency virus type 1 infection. N Engl J Med 1995;332:201-8
4. 4 Hogervorst E, Jurriaans S, de Wolf F et al. Predictors for non-slow progression in human immunodeciency virus (HIV) type 1 infection: low viral RNA copy numbers in serum and maintenance of high HIV-1 p24 specific but not V3-specific antibodiy levels. J Infect Dis 1995;171:811-21
5. 5 Veugelers PJ, Page KA, Schechter MT et al. Determination of HIV disease progression among homosexual men registred in the tricontinental seroconverter study. Am J Epidemiol 1994;140:747-58
6. 6 Munoz A, Wang MC, Bass S et al. Acquired immunodeficiency syndrome (AIDS)-free time after human immunodeficiency vims type 1 (HIV-1) seroconversion in homosexual men. Am J Epidemiol 1989;130:530-9
7. 7 Keet IPM, Krol A, Klein MR et al. Caracteristics of long-term asymptomatic infection with human immunodeficiency virus type 1 in men with normal and low CD4+ cell counts. J Infect Dis 1994;169:1236-43
8. 8 Paxton WA, Martin SR, Tse D et al. Relative resistance to HIV-1 of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposures. Nat Med 1996;2:412-17
9. 9 Rowland-Jones S, Sutton J, Dong T et al. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nat Med 1995;1:59-64
10. 10 Buchbinder SP, Katz MH, Hessol NA, OMalley PM, Holmberg SD. Long-term HIV-1 infection without immunologic progression. AIDS 1994;8:1123-8
11. 11 Tersmette M, de Goede REY, Al BJM et al. Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AID S-related complex. J Virol 1988;62:2026-32
12. 12 Tersmette M, Gruters R, de Wolf F et al. Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential isolates. J Virol 1989; 63:2118-25
13. 13 Roos MTL, Lange JMA, de Goede REY et al. Viral phenotype and immune response in primary human immunodeficiency virus type infection. J Infect Dis 1992;165:427-32
14. 14 Schuitemaker H, Koot M, Koostra NA et al. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is asociated with a shift from monocytotropic to T-cell-tropic population. J Virol 1992;66:1354-60
15. 15 Connor RL, Ho DD. Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression. J Virol 1994;68:4400-8
16. 16 Koot M, Keet IP, Vos AH et al. Prognosis value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS. Ann Intern Med 1993;118:681-8
17. 17 Choe H, Farzan M, Sun Y et al. The B-chemokine receptors CCR3 and CCR5 facilate infection by primary HIV-1 isolates. Cell 1996;85:1135-48
18. 18 Deng, H, Liu R, Ellmeier W et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996;381:661-6
19. 19 Watkins BA, Reitz MS, Wilson CA, Aldrich K, Davis AE, Robert-Guroff M. Immune escape by human immunodeficiency virus type 1 from neutralising antibodies: evidence for multiply pathways. J Virol 1993;67:7493-500
20. 20 Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, Desrosiers RC. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 1992;258:1938-41
21. 21 Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL, Desrosiers RC. Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N Engl J Med 1995;332:228-32
22. 22 Learmont J, Tindall B, Evans L et al. Long-term symptomless HIV-1 infection in recipients of blood products from a single donor. Lancet 1992;340:863-7
23. 23 Baba TW, Jeong YS, Penninck D, Bronson R, Greene MF, Ruprecht RM. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 1995;267:1820-5
24. 24 Fauci AS. Multifactorial nature of human immunodeficiency virus disease: Implication for therapy. Science 1993:262:1011-18
25. 25 Saksela K, Stevens C, Rubenstein P, Baltimore D. Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytes. PNAS 1994;91:1104-8
26. 26 Gupta P, Kingsley L, Amstrong J, Ding M, Cottrill M, Rinaldo C. Enhanced expression of human immunodeficiency virus type 1 correlates with development of AIDS. J Virol 1993;196:586-95
27. 27 Wei X, Sajal K, Taylor ME et al. Viral dynamics in human immunodeficiency viris type 1 infection. Nature 1995;373:117-22
28. 28 Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowittz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995;373:123-26
29. 29 Mellors JW, Rinaldo Jr CR, Gupta P, White RM, Todd JA, Kingsley LA. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 1996;272:1167-70
30. 30 Koot M, vant Wout AB, Kootstra NA, de Goede RE, Tersmette M, Schuitemaker H. Relation between changes in cellular load, evolution of viral phenotype, and the clonal composition of virus populations in the course of human immunodeficiency virus type 1 infection. J Infect Dis 1996;173:349-54
31. 31 Margoick JB, Munoz A, Donnenberg AD et al. Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. Nat Med 1995;1:674-8
32. 32 Ho HN, Hultin LE, Mitsuyasu RT et al. Circulating HIV-specific CD8+ cytotoxic T cell express CD38 and HLA-DR antigens. J Immunol 1993;150:3070-9
33. 33 Ramzaoui S, Jouen-Beades F, Gilbert D et al. During HIV infection, CD4+ CD38+ T cells are the predominant circulating CD4+ subset whose HLA-DR positivity increases with disease progression and whose V beta repertoire is similar to that of CD4+ CD38-T-cells. Clin Immunol Immunopathol 1995;77:33-41
34. 34 Caruso A, Licenziati S, Canaris AD et al. CD8 lymphocytosis in HIV-infected patients is sustained primarily by IFN-alpha-producing elements: correlation between the number of INF-alpha+ and CD4+ lymphocytes in patients. AIDS Sciences 1996;3:74-80
35. 35 Landay AL, Mackewicz CE, Levy JA. An activated CD8+ T cell phenotype correlates with anti-HIV activity and asymptomatic clinical status. Clin Immunol Immunopathol 1993;69:106-16
36. 36 Miedema F, Wolthers KC, Wisman B et al. Telomere shortening, a biomarker for T cell replicative capacity and renewal in HIV infection. Institute of Hum Virol Annual Meeting [abstract 32], Oral Communication 1996
37. 37 Clerici M, Shearer GM. A Th1-Th2 swith is a critical step in the etiology of HIV infection. Immunol Today 1993;14:107-11
38. 38 Autran B, Hadida F, Théodorou I et al. HIV-specific CD4 and CD8 T cell responses and immunogenetic studies in the cohort of 90 long term non progressors (LTNP). Institute of Human Virology Annual Meeting [abstract 77], Oral Communication 1996
39. 39 Kaslow RA, Ostrow DG, Detels R, Phair JP, Polk F, Rinaldo CR. The multicenter AIDS cohort study: rationale, organisation, and selected characteristics of the participants. Am J Epidemiol 1987;126:310-18
40. 40 Goedert JJ, Biggar RJ, Winn DM et al. Original contributions: Decreased helper T lymphocytes in homosexual men. Am J Epidemiol 1985;121:629-36
41. 41 Kaslow RA, Carrington M, Apple R et al. Influence of combinations of human major histocompatibility complex genes on the cource of HIV-1 infection. Nat Med 1996;2:405-11
42. 42 Kaplan C, Muller JY, Doinel C et al. HLA-associated susceptobility to acquired immune deficiency sundrome in HIV-1 seropositive subjects. Hum Hered 1990;40:290-8
43. 43 Steel CM, Beaston D, Cuthbert RJG et al. HLA haplotype A1 B8 DR3 as a risk factor for HIV-related disease. Lancet 1988;i:1185-8
44. 44 Just JJ, Abrams E, Louie LG et al. Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. J Pediat 1995;127:544-9
45. 45 Fabio G, Smetaldi RS, Gringeri A, Marchini M, Bonara P, Mannicci PM. Susceptibility to HIV infection and AIDS in Italian haemophiliacs is HLA associated. Br J Haematol 1990;75:531-6
46. 46 Kaslow RA, Duquesnoy R, VanRaden M et al. A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the multicenter AIDS Cohort Study. Lancet 1990;335:927-30
47. 47 Cameron PU, Mallal SA, French MAH, Dawkins RL. Major histocompatibility complex genes influence the outcome of HIV infection: Ancestral haplotypes with C4 null alleles explain diverse HLA associations. Hum Immunol 1990;29:282-95
48. 48 Hentges. F, Hoffmann A, Oliveira de Araujo F, Hemmer R. Prolonged clinically asymptomatic evolution after HIV-1 infection is marked by the absence of complement C4 null alleles at the MHC. Clin Exp Immunol 1992;88:237-42
49. 49 Sahmoud T, Laurian Y, Gazengel C, Sultan Y, Gautreau C, Costagliola D. Progression to AIDS in French haemophiliacs: association with HLA-B35. AIDS 1993;7:497-500
50. 50 Rubenstein P, Stevens CE. A prospective study of HLA-AIDS associations in homosexual men from New York City (abstract). Hum Immunol 1992;34 (suppl):33
51. 51 Mann DL, ODonnell, Carrington M, Goedert JJ. HLA alleles associated with relative rates of disease progression and different AIDS diagnosis in HIV-1-infected individuals (abstract). Hum Immunol 1992;34 (suppl):32
52. 52 Scorza Smeraldi R, Fabio G, Lazzarin A, Eisera N, Uberti Foppa C, Moroni M, Zanussi C. HLA-associated susceptibility to AIDS: HLA B35 is a major risk factor for Italian HIV-infected intravenous drug addicts. Hum Immunol 1988;22:73-9
53. 53 Klein MR, Keet IPM, D'Amaro et al. Association between HLA frequencies and pathologenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam Cohort of homosexual men. J Infect Dis 1994;169:1244-9
54. 54 Iteseu S, Mathur-Wagh U, Skovron ML et al. HLA-B35 is associated with accelerated progression to AIDS. J AIDS 1991;5:37-45
55. 55 Brakin MN, Lewis RE, Brakin BT et al. Progression of HIV infection is associated with HLA-DQ antigens in Caucasians and African Americans. Pathobiologie 1995;63:22-41
56. 56 Kaslow RA, Mann DL. The role of the major histocompatibitity complex in human immunodeficiency virus infection-ever more complex. J Infect Dis 1994;169:1332-3
57. 57 Gozlan, M. Update on HIV transmission and pathogenesis. Lancet 1995;346:1290
58. 58 Cruse JM, Brackin MN, Lewis RE, Meeks W, Nolan R, Brackin B. HLA disease and protection in HIV infection among African Americans and Caucasians. Pathobiologie 1991;59:324-28
59. 59 Mann DL, Murray C, ODowell M, Blattner WA, Goedert JJ. HLA antigen frequencies in HIV-1-related Kaposis sarcoma. J AIDS 1990;3 (suppl):S51-5
60. 60 Cocchi F, DeVico AL, Garzino-demi A, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1A, and MIP-1B as a major HIV-suppressive factors produced by CD8+ T cells. Science 1995;270:1811-15
61. 61 Doranz BJ, Rucker J, Yi Y et al. A dual-tropic primary HIV-1 isolate that uses fusin and the B chemokine receptors CKR 5, CKR 3, and CKR-2b as fusion cofactors. Cell 1996;85:1149-58
62. 62 Dragic H, Litwin V, Allaway GP et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996;381:667-73
63. 63 Alkhatib G, Cambadiere C, Broder CC et al. CC CKR5: a RANTES, MIP-1A, MIP1B receptor as a fusion cofactor for macrophages-tropic HIV-1. Science 1996;272:1955-8
64. 64 Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996;272:872-7
65. 65 Samson. M et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-5
66. 66 Liu R, Paxton WA, Choe S et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996; 86:367-77
67. 67 Dean M, Carrington M, Winkler C et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene; Science 1996;273:1856-62
68. 68 Hilgartner MW, Donfield SM, Willoughby A et al. Hemophilia growth and development study. Am J Pediat Hematol Oncol 1993;15;208-18
69. 69 Goedert JJ, Kessler CM, Aledort LM et al. A prospective study of human immunodeficiency virus type 1 infection and the devlopment of AIDS in subjects with hemophilia. N Eng J Med 1989;321:1141-8
70. 70 Vlahov D. NIDA Research Monograph Series 103. Public Health Service. Alcohol and Drug Abuse Administration, Washington DC, 1991
71. 71 Bleul CC, Farzan M, Choe H et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382:829-32
72. 72 Oberlin E, Amara A, Bachelerie F et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996;382:833-5