Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells

Journal of Medicinal Chemistry

Volumn 42, Issue 4, 1999, Pages 742-750

  Koch, Stacie S Canan ^a,b   Dardashti, Laura J ^a   Cesario, Rosemary M ^a   Croston, Glenn E ^a,c   Boehm, Marcus F ^a   Heyman, Richard A ^a   Nadzan, Alex M ^a,d  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b AGOURON PHARMACEUTICALS INC   (United States)

^c ACADIA PHARMACEUTICALS INC   (United States)

^d Chugai Biopharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEXAROTENE; LIGAND; OXIME DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOID DERIVATIVE; RETINOID X RECEPTOR; REXINOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN 3T3; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LIPOGENESIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; POLYMERIZATION; PROADIPOCYTE; REACTION ANALYSIS; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ADIPOCYTES; ANIMALS; BENZOIC ACIDS; BINDING, COMPETITIVE; CELL DIFFERENTIATION; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; LIGANDS; MICE; OXIMES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RETINOID X RECEPTORS; TRANSCRIPTION FACTORS; TRANSFECTION; TRIGLYCERIDES;

EID: 0005016202     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980621r     Document Type: Article

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