Identification of the first retinoid X receptor homodimer antagonist

Journal of Medicinal Chemistry

Volumn 39, Issue 17, 1996, Pages 3229-3234

  Koch, S S C ^a   Dardashti, L J ^a   Hebert, J J ^a   White, S K ^a   Croston, G E ^a   Flatten, K S ^a   Heyman, R A ^a   Nadzan, A M ^a  

^a LIGAND PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYL 7 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 3 PROPOXY 2 NAPHTHYL) 2,4,6 OCTATRIENOIC ACID; 6 [1 (5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHYL)CYCLOPROPYL]NICOTINIC ACID; BEXAROTENE; RECEPTOR BLOCKING AGENT; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; RETINOID X RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HL 60; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG COMPETITION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; RECEPTOR BLOCKING;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; DNA-BINDING PROTEINS; HL-60 CELLS; HUMANS; INDICATORS AND REAGENTS; KINETICS; MOLECULAR STRUCTURE; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RETINOID X RECEPTORS; RETINOIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0029763777     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960311d     Document Type: Article

References (0)