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Volumn 41, Issue 10, 1998, Pages 1679-1687

Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID DERIVATIVE;

EID: 15444345866     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970635h     Document Type: Article
Times cited : (60)

References (39)
  • 1
    • 0028838714 scopus 로고
    • Intracellular Receptors and Signal Transducers and Activators of Transcription Super-families: Novel Targets for Small-Molecule Drug Discovery
    • Rosen, J.; Day, A.; Jones, T. K.; Jones, E. T. T.; Nadzan, A. M.; Stein, R. B. Intracellular Receptors and Signal Transducers and Activators of Transcription Super-families: Novel Targets for Small-Molecule Drug Discovery. J. Med. Chem. 1995, 38, 4855-4874.
    • (1995) J. Med. Chem. , vol.38 , pp. 4855-4874
    • Rosen, J.1    Day, A.2    Jones, T.K.3    Jones, E.T.T.4    Nadzan, A.M.5    Stein, R.B.6
  • 3
    • 0028217849 scopus 로고
    • Retinoids and Vertebrate Development
    • (b) Gudas, L. Retinoids and Vertebrate Development. J. Biol. Chem. 1994, 269, 15399-15402.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15399-15402
    • Gudas, L.1
  • 4
    • 77956805124 scopus 로고
    • Retinoids for the Treatment of Oncological Diseases
    • Nadzan, A. M. Retinoids for the Treatment of Oncological Diseases. Annu. Rep. Med. Chem. 1995, 30, 119-128.
    • (1995) Annu. Rep. Med. Chem. , vol.30 , pp. 119-128
    • Nadzan, A.M.1
  • 7
    • 0030280090 scopus 로고    scopus 로고
    • Juvenile Myelomonocytic Leukemia: Molecular Understanding and Prospects for Therapy
    • Emanuel, P. D.; Shannon, K. M.; Castleberry, R. P. Juvenile Myelomonocytic Leukemia: Molecular Understanding and Prospects for Therapy. Mol. Med. Today 1996, 2, 468-475.
    • (1996) Mol. Med. Today , vol.2 , pp. 468-475
    • Emanuel, P.D.1    Shannon, K.M.2    Castleberry, R.P.3
  • 8
    • 15444343195 scopus 로고    scopus 로고
    • (UAB Research Foundation) Retinoid Compounds. U.S. Patent 5,094,783, March 10, 1992
    • Muccio, D. D.; Brouillette, W. J. (UAB Research Foundation) Retinoid Compounds. U.S. Patent 5,094,783, March 10, 1992.
    • Muccio, D.D.1    Brouillette, W.J.2
  • 9
    • 9544242711 scopus 로고    scopus 로고
    • Conformationally Defined 6-s-transRetinoic Acid Analogues. 3. Structure-Activity Relationships for Nuclear Receptor Binding, Transcriptional Activity, and Cancer Chemoprevention
    • Muccio, D. D.; Brouillette, W. J.; Alam, M.; Vaezi, M.; Sani, B. P.; Venepally, P.; Reddy, L.; Li, E.; Norris, A. W.; SimpsonHerren, L.; Hill, D. L. Conformationally Defined 6-s-transRetinoic Acid Analogues. 3. Structure-Activity Relationships for Nuclear Receptor Binding, Transcriptional Activity, and Cancer Chemoprevention. J. Med. Chem. 1996, 39, 3625-3635.
    • (1996) J. Med. Chem. , vol.39 , pp. 3625-3635
    • Muccio, D.D.1    Brouillette, W.J.2    Alam, M.3    Vaezi, M.4    Sani, B.P.5    Venepally, P.6    Reddy, L.7    Li, E.8    Norris, A.W.9    SimpsonHerren, L.10    Hill, D.L.11
  • 14
    • 0026536522 scopus 로고
    • Retinoid X Receptor is an Auxiliary Protein for Thyroid Hormone and Retinoic Acid Receptors
    • Zhang, X.-k.; Hoffmann, B.; Tran, P.; Graupner, G.; Pfahl, M. Retinoid X Receptor is an Auxiliary Protein for Thyroid Hormone and Retinoic Acid Receptors. Nature (London) 1992, 355, 441-446.
    • (1992) Nature (London) , vol.355 , pp. 441-446
    • Zhang, X.-K.1    Hoffmann, B.2    Tran, P.3    Graupner, G.4    Pfahl, M.5
  • 15
    • 0017647426 scopus 로고
    • Vitamin A Acid (Retinoic Acid), a Potent Inhibitor of 12-O-Tetradecanoylphorbol-13-acetate-induced Ornithine Decarboxylase Activity in Mouse Epidermis
    • Verma, A.; Boutwell, R. Vitamin A Acid (Retinoic Acid), a Potent Inhibitor of 12-O-Tetradecanoylphorbol-13-acetate-induced Ornithine Decarboxylase Activity in Mouse Epidermis. Cancer Res. 1977, 37, 2196-2201.
    • (1977) Cancer Res. , vol.37 , pp. 2196-2201
    • Verma, A.1    Boutwell, R.2
  • 16
    • 0025651334 scopus 로고
    • Growth and Differentiation of Human Myeloid Leukemia Cell Line HL60
    • (a) Breitman, T. R. Growth and Differentiation of Human Myeloid Leukemia Cell Line HL60. Methods Enzymol. 1990, 190, 118-130.
    • (1990) Methods Enzymol. , vol.190 , pp. 118-130
    • Breitman, T.R.1
  • 17
    • 0031561728 scopus 로고    scopus 로고
    • Growth, Differentiation, and Death of Retinoic Acid-Treated Human Acute Promyelocytic Leukemia NB4 Cells
    • (b) Taimi, M.; Breitman, T. R. Growth, Differentiation, and Death of Retinoic Acid-Treated Human Acute Promyelocytic Leukemia NB4 Cells. Exp. Cell Res. 1997, 230, 69-75.
    • (1997) Exp. Cell Res. , vol.230 , pp. 69-75
    • Taimi, M.1    Breitman, T.R.2
  • 18
    • 0026006684 scopus 로고
    • The Role of Monocyte-Derived Hemopoietic Growth Factors in the Regulation of Myeloproliferation in Juvenile Chronic Myelogemous Leukemia
    • (a) Emanuel, P. D.; Bates, L. J.; Zhu, S.-W.; Castleberry, R. P.; Gualtieri, R. J.; Zuckerman, K. S. The Role of Monocyte-Derived Hemopoietic Growth Factors in the Regulation of Myeloproliferation in Juvenile Chronic Myelogemous Leukemia. Exp. Hematol. 1991, 19, 1017-1024.
    • (1991) Exp. Hematol. , vol.19 , pp. 1017-1024
    • Emanuel, P.D.1    Bates, L.J.2    Zhu, S.-W.3    Castleberry, R.P.4    Gualtieri, R.J.5    Zuckerman, K.S.6
  • 19
    • 0026063878 scopus 로고
    • Selective Hypersensitivity to Granulocyte-Macrophage ColonyStimulating Factor by Juvenile Chronic Myeloid Leukemia Hematopoietic Progenitors
    • (b) Emanuel, P. D.; Bates, L. J.; Zhu, S.-W.; Castleberry, R. P.; Gualtieri, R. J.; Zuckerman, K. Selective Hypersensitivity to Granulocyte-Macrophage ColonyStimulating Factor by Juvenile Chronic Myeloid Leukemia Hematopoietic Progenitors. Blood, 1991, 77, 925-929.
    • (1991) Blood , vol.77 , pp. 925-929
    • Emanuel, P.D.1    Bates, L.J.2    Zhu, S.-W.3    Castleberry, R.P.4    Gualtieri, R.J.5    Zuckerman, K.6
  • 20
    • 0031518491 scopus 로고    scopus 로고
    • A Structural Model for a New Class of Conformationally Constrained Retinoid: (2Z,4E)-4-[3′, 4′-dihydro-l′(2′H) naphthalene1′-ylidene]-2-butenoic acid
    • Lake, C. H.; Alam, M. A.; Muccio, D. D.; Brouillette, W. J. A Structural Model for a New Class of Conformationally Constrained Retinoid: (2Z,4E)-4-[3′, 4′-dihydro-l′(2′H) naphthalene1′-ylidene]-2-butenoic acid. J. Chem. Crystallogr. 1997, 27, 231-235.
    • (1997) J. Chem. Crystallogr. , vol.27 , pp. 231-235
    • Lake, C.H.1    Alam, M.A.2    Muccio, D.D.3    Brouillette, W.J.4
  • 21
    • 0017816767 scopus 로고
    • Determination of Binding Affinities of Retinoids to Retinoic Acid-Binding Protein and Serum Albumin
    • (a) Sani, B. P.; Titus, B. C.; Banerjee, C. K. Determination of Binding Affinities of Retinoids to Retinoic Acid-Binding Protein and Serum Albumin. Biochem. J. 1978, 171, 711-717.
    • (1978) Biochem. J. , vol.171 , pp. 711-717
    • Sani, B.P.1    Titus, B.C.2    Banerjee, C.K.3
  • 22
    • 85053089745 scopus 로고
    • Cellular Retinoic Acid-Binding Protein and the Action of Retinoic Acid
    • Dawson, M. I., Okamuar, W. H., Eds.; CRC Press: Boca Raton, FL
    • (b) Sani, B. P. Cellular Retinoic Acid-Binding Protein and the Action of Retinoic Acid. In Chemistry and Biology of Synthetic Retinoids; Dawson, M. I., Okamuar, W. H., Eds.; CRC Press: Boca Raton, FL, 1990; pp 365-384.
    • (1990) Chemistry and Biology of Synthetic Retinoids , pp. 365-384
    • Sani, B.P.1
  • 23
    • 0024385540 scopus 로고
    • Dual Regulatory Role for Thyroid Hormone Receptors Allows Control of Retinoic Acid Receptor Activity
    • Graupner, G.; Wills, K. N.; Tzukerman, M.; Zhang, X.-k.; Pfahl, M. Dual Regulatory Role for Thyroid Hormone Receptors Allows Control of Retinoic Acid Receptor Activity. Nature (London) 1989, 340, 653-656.
    • (1989) Nature (London) , vol.340 , pp. 653-656
    • Graupner, G.1    Wills, K.N.2    Tzukerman, M.3    Zhang, X.-K.4    Pfahl, M.5
  • 25
    • 0028950218 scopus 로고
    • Separation of Transcription and API Antagonism Functions of Retinoic Acid Receptor a
    • (b) Nagpal, S.; Athanikar, J.; Chandraratna, R. A. S. Separation of Transcription and API Antagonism Functions of Retinoic Acid Receptor a. J. Biol. Chem. 1995, 270, 923-927.
    • (1995) J. Biol. Chem. , vol.270 , pp. 923-927
    • Nagpal, S.1    Athanikar, J.2    Chandraratna, R.A.S.3
  • 27
    • 12944270063 scopus 로고
    • Aberrant Growth Properties of Juvenile Chronic Myelogenous Leukemia (JCML) CD34+ Cells in Vitro and in Vivo using SCID Mouse Assays
    • (a) Lapidot, T.; Cohen, A.; Grunberger, T.; Dick, J.; Freedman, M. H. Aberrant Growth Properties of Juvenile Chronic Myelogenous Leukemia (JCML) CD34+ Cells in Vitro and in Vivo using SCID Mouse Assays, Blood 1993, 82 (Suppl. 1), 197a.
    • (1993) Blood , vol.82 , Issue.SUPPL. 1
    • Lapidot, T.1    Cohen, A.2    Grunberger, T.3    Dick, J.4    Freedman, M.H.5
  • 28
    • 4244053499 scopus 로고
    • GM-CSF Hypersensitivity in CD34+ Purified Cells in Juvenile and Adult Chronic Myelomonocytic Leukemia: Effects of Retinoids
    • (b) Cambier, N.; Menot, M. L.; Fenaux, P.; Wattel, E.; Baruchel, A.; Chomienne, C. GM-CSF Hypersensitivity in CD34+ Purified Cells in Juvenile and Adult Chronic Myelomonocytic Leukemia: Effects of Retinoids. Blood 1995, 86 (Suppl 1), 791a.
    • (1995) Blood , vol.86 , Issue.SUPPL. 1
    • Cambier, N.1    Menot, M.L.2    Fenaux, P.3    Wattel, E.4    Baruchel, A.5    Chomienne, C.6
  • 29
    • 15444341810 scopus 로고
    • Characterization of Early Response Gene Expression in Juvenile Myelomonocytic Leukemia Syndrome (JMML)
    • Emanuel, P. D.; Sokol, J. M.; Castleberry, R. P. Characterization of Early Response Gene Expression in Juvenile Myelomonocytic Leukemia Syndrome (JMML). Blood 1995, 86 (Suppl 1), 728a.
    • (1995) Blood , vol.86 , Issue.SUPPL. 1
    • Emanuel, P.D.1    Sokol, J.M.2    Castleberry, R.P.3
  • 30
    • 0026316847 scopus 로고
    • Antagonism between Retinoic Acid Receptors and AP-1: Implications for Tumor Promotion and Inflammation
    • (a) Yang Yen, H.-F.; Zhang, X.-K.; Graupner, G.; Tzukerman, M.; Sakamoto, B.; Karin, M.; Pfahl, M. Antagonism between Retinoic Acid Receptors and AP-1: Implications for Tumor Promotion and Inflammation. New Biol. 1991, 3, 1206-1219.
    • (1991) New Biol. , vol.3 , pp. 1206-1219
    • Yang Yen, H.-F.1    Zhang, X.-K.2    Graupner, G.3    Tzukerman, M.4    Sakamoto, B.5    Karin, M.6    Pfahl, M.7
  • 32
    • 0027521592 scopus 로고
    • Nuclear Receptor/ AP-1 Interactions
    • (c) Pfahl, M. Nuclear Receptor/ AP-1 Interactions. Endocrine Rev. 1993, 14, 651-658.
    • (1993) Endocrine Rev. , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 33
    • 0027521292 scopus 로고
    • Retinoic Acid Receptors and Retinoid X Receptor-α Down-Regulate the Transforming Growth Factor-β1 Promoter by Antagonizing AP-1 Activity
    • Salbert, G.; Fanjul, A.; Piedrafita, F. J.; Lu, X. P.; Kim, S.-J.; Tran, P.; Pfahl, M. Retinoic Acid Receptors and Retinoid X Receptor-α Down-Regulate the Transforming Growth Factor-β1 Promoter by Antagonizing AP-1 Activity. Mol. Endocrinol. 1993, 7, 1347-1356.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1347-1356
    • Salbert, G.1    Fanjul, A.2    Piedrafita, F.J.3    Lu, X.P.4    Kim, S.-J.5    Tran, P.6    Pfahl, M.7
  • 35
    • 0028950218 scopus 로고
    • Separation of Transactivation and API Antagonism Functions of Retinoic Acid Receptor α
    • (b) Nagpal, S.; Athanikar, J.; Chandraratna, R. A. S. Separation of Transactivation and API Antagonism Functions of Retinoic Acid Receptor α. J. Biol. Chem. 1995, 270, 923-927.
    • (1995) J. Biol. Chem. , vol.270 , pp. 923-927
    • Nagpal, S.1    Athanikar, J.2    Chandraratna, R.A.S.3
  • 36
    • 0028362475 scopus 로고
    • Novel Retinoic acid, 9-Cis Retinoic Acid, in Combination with All-Trans Retinoic Acid Is an Effective Inducer of Differentiation of Retinoic AcidResistance HL-60 Cells
    • (a) Kizaki, M.; Nakajima, H.; Mori, S.; Koike, T.; Morikawa, M.; Ohta, M.; Saito, M.; Koeffler, H. R.; Ikeda, Y. Novel Retinoic acid, 9-Cis Retinoic Acid, in Combination with All-Trans Retinoic Acid Is an Effective Inducer of Differentiation of Retinoic AcidResistance HL-60 Cells. Blood 1994, 83, 3289-3297.
    • (1994) Blood , vol.83 , pp. 3289-3297
    • Kizaki, M.1    Nakajima, H.2    Mori, S.3    Koike, T.4    Morikawa, M.5    Ohta, M.6    Saito, M.7    Koeffler, H.R.8    Ikeda, Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.